• Journal of Chest Surgery
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• v.43 no.2
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• pp.217-220
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• 2010

Pleomorphic adenoma is also called a mixed tumor and it most commonly occurs in the salivary gland. This neoplasm has a low grade malignant potential, but it may also show aggressive clinical behavior like recurrence or metastasis. We report here on a case of a tumor that was confirmed to be primary pulmonary carcinoma ex-pleomorphic adenoma by the pathologic examination after complete resection, and it had the characteristics of malignant neoplasms, such as multiple metastases.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.7
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• pp.2515-2521
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• 2010

The aim of this study is to analyze the mortality and potential years of life lost (PYLL) by malignant neoplasm of lung between OECD countries and Korea. Based on the result, we tried to point out a problem on mortality caused malignant neoplasm of lung to make the best strategy for policy and education on public health. Using the ANOVA analysis between Korean and OECD countries, the lung cancer-induced mortality and PYLL in total and gender-specific Korean population were greater after 21th century than before. In particular, the PYLL was sharply elevated than the mortality. Taken together, the present study indicated that the lung cancer-induced PYLL between Korean and OECD countries can be more important parameter.

• Journal of Chest Surgery
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• v.31 no.3
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• pp.315-318
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• 1998

Primary hemangioperiycytoma is quite rare tumor of the lung and arising from pericyte in external layer of capillaries. Most cases are developed in 4th and 5th decade, are asymptomatic, and have malignant otential. On chest radiography, primary pulmonary hemangiopericytoma shows lobulated, well demarcated, homogeneous soft tissue density. Microscopically, it consisits of numerous vascular spaces of variable size and shape separated by aggregates of tightly packed oval to spindle-shaped cells. Treatment of choice is surgical excision. We report a case of primary pulmonary hemangiopericytoma in a 16-year-old man who had well demarcated homogeneous mass in the superior segment of left lower lobe, but had no symptom. He had undergone left lower lobectomy. He has been followed up for 8 months but has no sign of relapse or metastasis yet.

• Journal of Chest Surgery
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• v.36 no.12
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• pp.943-951
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• 2003

We are now detecting an increasing number of solitary pulmonary nodules (SPNs) that are difficult to diagnosis. The purpose of this study was to evaluate the useful radiologic findings for differentiating benign from malignant pulmonary nodules. Material and Method: The high-resolution CT (HRCT) findings of SPNs smaller than 3 cm in largest diameter were evaluated in 134 patients with malignant and benign nodules in regard to internal structures, margin characteristics, and surrounding parenchymal responses. Result: The nodules with the area of ground-glass attenuation (GGA) greater then 50% were noted in adenocarcinoma, inflammatory lesions and some of metastatic tumors, and the lesions greater than 90% were noted only in adenocarcinoma. The area of GGA in non-adenocarcinoma, benign tumors and tuberculomas were less than 50%, and mainly less than 10%. The findings of air bronchogram, spiculation, lobulation, vascular involvement, and pleural indentation were some noted at every types of malignant tumors, but especially high over than 30% in adenocarcinomas. Conclusion: Most peripheral lung adenocarcinomas form a characteristic radiologic findings especially in HRCT. Evaluation of these findings would be helpful in differentiating between lung cancer, especially adenocarcinoma, and other lesions.

• Journal of Chest Surgery
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• v.40 no.2 s.271
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• pp.143-146
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• 2007

A metastasizing pleomorphic adenoma originating from the parotid gland is a rare form of neoplasm. The neoplasm is a histologically benign, but clinically controversial entity. Herein, a case report of a pleuro-pneumonectomy of a metastasizing pleomorphic adenoma in the right lung is described. A 57-year-old man, who underwent resection of parotid gland due to a pleomorphic adenoma, presented with multiple metastases on the right lung, mediastinum, pericardium and intercostal muscle. The metastatic lesions were composed of a benign pleomorphic structure.

• Journal of Chest Surgery
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• v.40 no.11
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• pp.786-788
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• 2007

Primary malignant fibrous histiocytoma of the lung is extremely rare, A 12-year-old child was admitted to the hospital due to an incidentally detected lung mass. A $2.5{\times}2.5 cm$ sized mass located in the right lower lobe was seen on the chest X-ray, the chest computed tomogram and the positron emission tomogram. We resected the mass through a right lateral thoracotomy and the mass was revealed to be a malignant spindle cell neoplasm on the frozen section diagnosis. So, we performed lobectomy of the right lower lobe with systemic dissection of the mediastinal lymph nodes; the final histopathological diagnosis of the mass was malignant fibrous histiocytoma. The patient was discharged on postoperative day 7 and adjuvant chemotherapy was not applied.

• Journal of Chest Surgery
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• v.31 no.2
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• pp.212-215
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• 1998

Pulmonary mucinous cystic tumor of borderline malignancy is very rare and distinguished from bronchogenic cyst or adenocarcinoma of bronchoalveolar type. We present the case of a 63-year-old woman with a right lower lobe mass, found by chest radiographs. The preoperative diagnosis was made as bronchoalveolar cancer by percutaneous needle aspiration of mass. Right lower lobectomy and lymph node dissections were performed. The lobectomy specimen contained variable sized multilocular cystic mucous masses, filled with mucus. Microscopically, the cystic masses are lined with tall columnar mucinous epithelium but some area contains focal cellular atypism and bronchoalveolar cancer like foci. This foci are lack of cellular atypism consistent with bronchoalveolar cancer cell. After lobectomy the patient has remained free from recurrence and distant metastasis for following 12 months period. Pulmonary mucinous cystic tumor of borderline malignancy appears to have a favorable prognosis and should be distinguished from other lung neoplasms.

• Journal of Chest Surgery
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• v.37 no.11
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• pp.959-962
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• 2004

Pleuropulmonary blastoma is a rare malignant neoplasm which originates from either the lungs or pleura. Pleuropulmonary blastoma usually develops in the first decade of life, mostly younger than 5 years old and shows aggressive biological behavior. Pleuropulmonary blastoma is discriminated from classic pulmonary blastoma of adulthood by its morphological features like primitive mesenchymal and sarcomatous component without carcinomatous portions. To our knowledge, report of pleuropulmonary blastoma in adulthood is very rare. Our case support the possibility that primitive neoplasm recognized as pediatric tumors can develop in adulthood. We report a case of surgical experience of pleuropulmonary blastoma which developed in 21 years old man with literature review.

• Journal of Chest Surgery
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• v.34 no.5
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• pp.386-392
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• 2001

배경: 기관지에 광범위한 협착을 가지고 있는 환자들에게서 협착된 기관지 이하 부위에 있는 폐를 절제하지 않고 기관지 협착 부위를 교정하여 폐환기를 원할하게 하고자 하는 다양한 술식의 기관지 성형술이 고안시도되어 왔지만 만족할만한 술기는 아직 정립되어 있지 않다. 저자들은 이러한 기관지 협착을 교정하기 위한 술식의 하나로서 기관지 대치물을 이용한 기관 성형술의 효과를 조사하기 위하여 본 실험을 시행하였다. 대상 및 방법: 기관지 대치물로 사용한 두 종류의 첨포에 따라 성숙견을 실험 동물로 하여 두 군으로 분류하였으며 A군(5예)에서는 좌측 주기관지 전측방 부위를 0.5$\times$0.5cm 크기의 직사각형으로 절제한 후 늑연골에 자가 심낭편을 댄 동일한 크기의 첨포를 절제 부위에 부착하였고 B군(5예)에서는 동일한 크기의 기관지 절제 부위에 glutaraldehyde로 처리된 우심낭편을 부착하였다. 첨포를 이용한 기관지 성형술 12주후에 실험견을 도살하고 육안적 및 현미경적으로 관찰하였다. 결과: A군이 기관지 성형술 부위에서는 첨포의 외면은 주위의 결합조직과 막상유착을 이루고 있었으며 첨포의 가장자리는 자가 기관지에 잘 부착되어 있었다. 기관지 내면은 내경의 협착이 없이 윤기 있는 점막으로 잘 유지되어 있었고 자가 기관지와 첨호와의 경계면은 신생육아조직이 일부 차지하고 있었으며 새로운 이행 상피가 가교를 이루고 있는 현미경적 소견을 보았다. B군의 기관지 성형술 부위에서는 첨포의 와부는 암갈색으로 변화된 부분적 괴사의 양상을 보였다. 기관지 내면은 첨포와 가자기관지 경계부위에서 염증성 육아조직과 부분적 출현 양상을 보고 기관지 내경의 일부가 수축되었으며 자가 기관지로부터 첨포내로의 새로운 상피 형성은 되어 있지 않았다. 결론: 늑연골에 자가 심낭편을 댄 첨포는는 자가 기관지와 상피 가교를 형성하고 기관지 내강의 협착이 없이 구조를 유지하므로 기관지 협착 및 결손의 치료를 위한 기관지 성형술시에 기관지 대치물로 사용될수 있는 것으로 사료된다.

• Journal of Chest Surgery
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• v.29 no.5
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• pp.517-523
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• 1996

From May 1988 to June 1994, )73 patients underwent exploratory thoracotomy for resection of non- small cell lung cancer, and 48 patients staged pathologically as lIIB were analyzed. 74 lesions were involvement of great vessel (n=26), heart (n=5), ipsilateral lung metastasis(n=4), esophagus (n=4), carina(n=3), mediastinum (n=2), trachea(n=1), spine (n=1) and 13lourO seeding(A=15). N3 lesions were involved in 6 patients. Extended pulmonary resection with radical mediastinal node dissection was possible in 25 patients, and exploration only was performed in 23 patients. The most frequent cause of unresectability was pleural seeding. Postoperative morbidity was )2 % (8125) and mortality was 16 % (41 25) in resected group. The adjutant therapy was given to 37 patients. The 1 year and 3 year survival for resected group ncluding operative deaths was 57.2%, and 2).8 % (median 15 months), but 48.4%, and 0 % (median 7 months) for exploration only group (Log-Rank test, p : 0.17). Our results suggest that extended pulmonary resection might be helpful for carefully selected patients with 74 non-small cell lung cancer, but meticulous preoperative work-up for staging, especially to detect pleural seeding and Invasion to the irlediastinal structures is a prerequisite to avoid unnecessary thoracotomy.