• Title/Summary/Keyword: 폐 부피

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CComparative evaluation of the methods of producing planar image results by using Q-Metrix method of SPECT/CT in Lung Perfusion Scan (Lung Perfusion scan에서 SPECT-CT의 Q-Metrix방법과 평면영상 결과 산출방법에 대한 비교평가)

  • Ha, Tae Hwan;Lim, Jung Jin;Do, Yong Ho;Cho, Sung Wook;Noh, Gyeong Woon
    • The Korean Journal of Nuclear Medicine Technology
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    • v.22 no.1
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    • pp.90-97
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    • 2018
  • Purpose The lung segment ratio which is obtained through quantitative analyses of lung perfusion scan images is calculated to evaluate the lung function pre and post surgery. In this Study, the planar image production methods by using Q-Metrix (GE Healthcare, USA) program capable of not only quantitative analysis but also computation of the segment ratio after having performed SPECT/CT are comparatively evaluated. Materials and Methods Lung perfusion scan and SPECT/CT were performed on 50 lung cancer patients prior to surgery who visited our hospital from May 1, 2015 to September 13, 2016 by using Discovery 670(GE Healthcare, USA) equipment. AP(Anterior Posterior)method that uses planar image divided the frontal and rear images into three rectangular portions by means of ROI tool while PO(Posterior Oblique)method computed the segment ratio by dividing the right lobe into three parts and the left lobe into two parts on the oblique image. Segment ratio was computed by setting the ROI and VOI in the CT image by using Q-Metrix program and statistically analysis was performed with SPSS Ver. 23. Results Regarding the correlation concordance rate of Q-Metrix and AP methods, RUL(Right upper lobe), RML(Right middle lobe) and RLL(Right lower lobe) were 0.224, 0.035 and 0.447. LUL(Left upper lobe) and LLL(Left lower lobe) were found to be 0.643 and 0.456, respectively. In the PO method, the right lobe were 0.663, 0.623 and 0.702, respectively, while the left lobe were 0.754 and 0.823. When comparison was made by using the Paired sample T-test, Right lobe were $11.6{\pm}4.5$, $26.9{\pm}6.2$ and $17.8{\pm}4.2$, respectively in the AP method. Left lobe were $28.4{\pm}4.8$ and $15.4{\pm}5.6$. The right lobe of PO had values of $17.4{\pm}5.0$, $10.5{\pm}3.6$ and $27.3{\pm}6.0$, while the left lobe had values of $21.6{\pm}4.8$ and $23.1{\pm}6.6$, thereby having statistically significant difference in comparison to the Q-Metrix method for each of the lobes (P<0.05). However, there was no statistically significant difference in Right middle lobe (P>0.05). Conclusion The AP method showed low concordance rate in correlation with the Q-Metrix method. However, PO method displayed high concordance rate overall. although AP method had significant differences in all lobes, there was no significant difference in Right middle lobe of PO method. Therefore, at the time of production of lung perfusion scan results, utilization of Q-Metrix method of SPECT/CT would be useful in computation of accurate resultant values. Moreover, it is deemed possible to expect obtain more practical sectional computation result values by using PO method at the time of planar image acquisition.

Production of Silver Impregnated Bamboo Activated Carbon and Reactivity with NO Gases (은첨착 대나무 활성탄의 제조와 NO 가스 반응 특성)

  • Bak, Young-Cheol;Choi, Joo-Hong;Lee, Geun-Lim
    • Korean Chemical Engineering Research
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    • v.52 no.6
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    • pp.807-813
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    • 2014
  • The Ag-impregnated activated carbon was produced from bamboo activated carbon by soaking method of silver nitrate solution. The carbonization and activation of raw material was conducted at $900^{\circ}C$. Soaking conditions are the variation of silver nitrate solution concentration (0.002~0.1 mol/L) and soaking time (maximum 24 h). The specific surface area and pore size distribution of the prepared activated carbons were measured. Also, NO and activated carbon reaction were conducted in a thermogravimetric analyzer in order to use for de-NOx agents of used activated carbon. Carbon-NO reactions were carried out with respect to reaction temperature ($20{\sim}850^{\circ}C$) and NO gas partial pressure (0.1~1.8 kPa). As results, Ag amounts are saturated within 2h, Ag amounts increased 1.95 mg Ag/g (0.2%)~ 88.70 mg Ag/g (8.87%) with the concentration of silver nitrate solution in the range of 0.002~0.1 mol/L. The specific volume and surface area of bamboo activated carbon of impregnated with 0.2% silver were maximum, but decreased with increasing Ag amounts of activated carbon due to pore blocking. In NO reaction, the reaction rate of impregnated bamboo activated carbon was retarded as compare with that of bamboo activated carbon. Measured reaction orders of NO concentration and activation energy were 0.63[BA], 0.69l[BA(Ag)] and 80.5 kJ/mol[BA], 66.4 kJ/mol[BA(Ag)], respectively.

Kinetics of NO Reduction with Copper Containing Bamboo Activated Carbon (구리 촉매 담지 대나무 활성탄의 NO 가스 반응 특성)

  • Bak, Young-Cheol;Choi, Joo-Hong
    • Journal of Korean Society of Environmental Engineers
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    • v.38 no.3
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    • pp.144-149
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    • 2016
  • The metal-impregnated activated carbon was produced from bamboo activated carbon by soaking method of metal nitrate solution. The carbonization and activation of raw material was conducted at $900^{\circ}C$. The specific surface area and pore size distribution of the prepared activated carbons were measured. Also, NO and activated carbon reaction were conducted in a thermogravimetric analyzer in order to use as de-NOx agents of used activated carbon. Carbon-NO reactions were carried out with respect to reaction temperature ($20^{\circ}C{\sim}850^{\circ}C$) and NO gas partial pressure (0.1 kPa~1.8 kPa). As results, the specific volume and surface area of bamboo activated carbon impregnated with copper were decreased with increasing Cu amounts of activated carbon. In NO reaction, the reaction rate of Cu impregnated bamboo activated carbon[BA(Cu)] was promoted to compare with that of bamboo activated carbon[BA]. But the reaction rate of Ag impregnated bamboo activated carbon[BA(Ag)] was retarded. Measured reaction orders of NO concentration and activation energy were 0.63[BA], 0.92[BA(Cu)], and 80.5 kJ/mol[BA], 48.5 kJ/mol[BA(Cu)], 66.4 kJ/mol[BA(Ag)], respectively.

Stabilization/Solidification of Radioactive LiCl-KCl Waste Salt by Using SiO2-Al2O3-P2O5 (SAP) Inorganic Composite: Part 2. The Effect of SAP Composition on Stabilization/Solidification (SiO2-Al2O3-P2O5 (SAP) 무기복합체를 이용한 LiCl-KCl 방사성 폐기물의 안정화/고형화: Part 2. SAP조성에 따른 안정화/고형화특성 변화)

  • Ahn, Soo-Na;Park, Hwan-Seo;Cho, In-Hak;Kim, In-Tae;Cho, Yong-Zun
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.10 no.1
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    • pp.27-36
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    • 2012
  • Metal chloride waste is generated as a main waste streams in a series of electrolytic processes of a pyrochemical process. Different from carbonate or nitrate salt, metal chloride is not decomposed into oxide and chlorine but it is just vaporized. Also, it has low compatibility with conventional silicate glasses. Our research group adapted the dechlorination approach for the immobilization of waste salt. In this study, the composition of SAP ($SiO_2-Al_2O_3-P_2O_5$) was adjusted to enhance the reactivity and to simplify the solidification process as a subsequent research. The addition of $Fe_2O_3$ into the basic SAP decreased the SAP/Salt ratio in weight from 3 for SAP 1071 to 2.25 for M-SAP( Fe=0.1). The experimental results indicated that the addition of $Fe_2O_3$ increased the reactivity of M-SAP with LiCl-KCl but the reactivity gradually decreased above Fe=0.1. Also, introducing $B_2O_3$ into M-SAP requires no glass binder for the consolidation of reaction products. U-SAP ($SiO_2-Al_2O_3-Fe_2O_3-P_2O_5-B_2O_3$) could effectively dechlorinate the LiCl-KCl waste and its reaction product could be consolidated as a monolithic form without a glass binder. The leaching test result indicated that U-SAP 1071 was more durable than other SAPs wasteform. By using U-SAP, 1 g of waste salt could generated 3~4 g of wasteform for final disposal. The final volume would be about 3~4 times lower than the glass-bonded sodalite. From these results, it could be concluded that the dechlorination approach using U-SAP would be one of prospective methods to manage the volatile waste salt.

Impact of the Planning CT Scan Time on the Reflection of the Lung Tumor Motion (전산화단층촬영 주사시간(Scan Time)이 폐종양운동의 재현성에 미치는 영향 분석)

  • Kim Su Ssan;Ha Sung Whan;Choi Eun Kyung;Yi Byong Yong
    • Radiation Oncology Journal
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    • v.22 no.1
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    • pp.55-63
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    • 2004
  • Purpose : To evaluate the reflection of tumor motion according to the planning CT scan time. Material and Methods : A model of N-shape, which moved aiong the longitudinal axis during the ventilation caused by a mechanical ventilator, was produced. The model was scanned by planning CT, while setting the relative CT scan time (T: CT scan time/ventilatory period) to 0.33, 0.50, 0.67, 0.75, 1.00, 1.337, and 1.537. In addition, three patients with non-small cell lung cancer who received stereotactic radiosurgery In the Department of Radiation Oncology, Asan Medical Center from 03/19/2002 to 05/21/2002 were scanned. Slow (10 Premier, Picker, scan time 2.0 seconds per slice) and fast CT scans (Lightspeed, GE Medical Systems, with a scan time of 0.8 second per slice) were peformed for each patient. The magnitude of reflected movement of the N-shaped model was evaluated by measuring the transverse length, which reflected the movement of the declined bar of the model at each slice. For patients' scans, all CT data sets were registered using a stereotactic body frame scale with the gross tumor volumes delineated in one CT image set. The volume and three-dimensional diameter of the gross tumor volume were measured and analyzed between the slow and fast CT scans. Results : The reflection degree of longitudinal movement of the model increased in proportion to the relative CT scan times below 1.00 7, but remained constant above 1.00 T Assuming the mean value of scanned transverse lengths with CT scan time 1.00 T to be $100\%$, CT scans with scan times of 0.33, 0.50, 0.57, and 0.75 T missed the tumor motion by 30, 27, 20, and $7.0\%$ respectively, Slow (scan time 2.0 sec) and Fast (scan time 0.8 sec) CT scans of three patients with longitudinal movement of 3, 5, and 10 mm measured by fluoroscopy revealed the increases in the diameter along the longitudinal axis Increased by 6.3, 17, and $23\%$ in the slow CT scans. Conculsion : As the relative CT scan time increased, the reflection of the respiratory tumor movement on planning CT also Increased, but remained constant with relative CT scan times above 1.00 T When setting the planning CT scan time above one respiration period (>1.00 T), only the set-up margin is needed to delineate the planning target volume. Therefore, therapeutic ratio can be increased by reducing the radiation dose delivered to normal lung tissue.

Effects of Anti-thyroglobulin Antibody on the Measurement of Thyroglobulin : Differences Between Immunoradiometric Assay Kits Available (면역방사계수법을 이용한 Thyroglobulin 측정시 항 Thyroglobulin 항체의 존재가 미치는 영향: Thyroglobulin 측정 키트에 따른 차이)

  • Ahn, Byeong-Cheol;Seo, Ji-Hyeong;Bae, Jin-Ho;Jeong, Shin-Young;Yoo, Jeong-Soo;Jung, Jin-Hyang;Park, Ho-Yong;Kim, Jung-Guk;Ha, Sung-Woo;Sohn, Jin-Ho;Lee, In-Kyu;Lee, Jae-Tae;Kim, Bo-Wan
    • The Korean Journal of Nuclear Medicine
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    • v.39 no.4
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    • pp.252-256
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    • 2005
  • Purpose: Thyroglobulin (Tg) is a valuable and sensitive tool as a marker for diagnosis and follow-up for several thyroid disorders, especially, in the follow-up of patients with differentiated thyroid cancer (DTC). Often, clinical decisions rely entirely on the serum Tg concentration. But the Tg assay is one of the most challenging laboratory measurements to perform accurately owing to antithyroglobulin antibody (Anti-Tg). In this study, we have compared the degree of Anti-Tg effects on the measurement of Tg between availale Tg measuring kits. Materials and Methods: Measurement of Tg levels for standard Tg solution was performed with two different kits commercially available (A/B kits) using immunoradiometric assay technique either with absence or presence of three different concentrations of Anti-Tg. Measurement of Tg for patient's serum was also performed with the same kits. Patient's serum samples were prepared with mixtures of a serum containing high Tg levels and a serum containg high Anti-Tg concentrations. Results: In the measurements of standard Tg solution, presence of Anti-Tg resulted in falsely lower Tg level by both A and B kits. Degree of Tg underestimation by h kit was more prominent than B kit. The degree of underestimation by B kit was trivial therefore clinically insignificant, but statistically significant. Addition of Anti-Tg to patient serum resulted in falsely lower Tg levels with only A kit. Conclusion: Tg level could be underestimated in the presence of anti-Tg. Anti-Tg effect on Tg measurement was variable according to assay kit used. Therefore, accuracy test must be performed for individual Tg-assay kit.

Kinetics of Nitric Oxide Reduction with Alkali Metal and Alkali Earth Metal Impregnated Bamboo Activated Carbon (알칼리금속과 알칼리 토금속 촉매 담지 대나무 활성탄의 NO 가스 반응 특성)

  • Bak, Young-Cheol;Choi, Joo-Hong
    • Korean Chemical Engineering Research
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    • v.54 no.5
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    • pp.671-677
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    • 2016
  • The impregnated alkali metal (Na, K), and the alkali earth metal (Ca, Mg) activated carbons were produced from the bamboo activated carbon by soaking method of alkali metals and alkali earth metals solution. The carbonization and activation of raw material was conducted at $900^{\circ}C$. The specific surface area and the pore size distribution of the prepared activated carbons were measured. Also, NO and activated carbon reaction were conducted in a thermogravimetric analyzer in order to use for de-NOx agents of the used activated carbon. Carbon-NO reactions were carried out in the nonisothermal condition (the reaction temperature $20{\sim}850^{\circ}C$, NO 1 kPa) and the isothermal condition (the reaction temperature 600, 650, 700, 750, 800, $850^{\circ}C$, NO 0.1~1.8 kPa). As results, the specific volume and the surface area of the impregnated alkali bamboo activated carbons were decreased with increasing amounts of the alkali. In the NO reaction, the reaction rate of the impregnated alkali bamboo activated carbons was promoted to compare with that of the bamboo activated carbon [BA] in the order of BA(Ca)> BA(Na)> BA(K)> BA(Mg) > BA. Measured the reaction orders of NO concentration and the activation energy were 0.76[BA], 0.63[BA(Na)], 0.77[BA(K)], 0.42[BA(Ca)], 0.30 [BA(Mg)], and 82.87 kJ/mol[BA], 37.85 kJ/mol[BA(Na)], 69.98 kJ/mol[BA(K)], 33.43 kJ/mol[BA(Ca)], 88.90 kJ/mol [BA(Mg)], respectively.

The Application of B-Type Natriuretic Peptide Level of the Dyspneic Patients : Differentiation Between Cor Pulmonale and Left Ventricular Dysfunction (호흡곤란을 주소로 내원한 환자에서 혈청 B-type Natriuretic Peptide 검사의 유용성 : 폐성심과 좌심부전의 감별에 대하여)

  • Park, Hong-Hoon;Kim, Sehyun;Choi, Jeongeun;Kim, Kang-Ho;Cheon, Seok-Cheol;Lee, Jihyun;Lee, Yong-Gu;Kim, In-Jae;Cha, Dong-Hoon;Hong, Sang-Bum;Lee, Ji-Hyun
    • Tuberculosis and Respiratory Diseases
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    • v.54 no.3
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    • pp.320-329
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    • 2003
  • Background : The serum B-type natriuretic peptide (BNP) is released from the ventricles as a response to volume or pressure overload of the ventricles. A few studies have reported that the BNP measurements are useful in differentiating between heart failure and pulmonary causes in patients who visited the emergency department with dyspnea as the chief complaint. It is difficult to differentiate a right heart failure from a left heart failure in the emergency room. However, there is no report on the application of a BNP assay to differentiate in right heart failure from left heart failure. In this study, the BNP levels were measured from dyspneic patients in the emergency department to determine whether or not the BNP level would be useful in differentiating the cause of the dyspnea from right ventricular failure and left ventricular failure. Method : 89 patients who visited emergency department of the Bundang Cha Hospital with dyspnea from June 2002 to March 2003 were selected. The 29 patients from the outpatient clinics and inpatients were randomly selected as the control. Results : The BNP levels of patients in the left heart failure group were significantly different from that of the patients in the right heart failure group ($682{\pm}314$ pg/mL vs. $149{\pm}94$ pg/mL, p=0.000). When the BNP cut-off level was designated as 219 pg/mL using the receiver operating characteristic curve, the sensitivity was 94.3%, and specificity was 92.9%. In addition, the positive predictive value was 97% and the negative predictive value was 86.7% in differentiating right heart failure from left heart failure. Conclusion : Measurements of the serum BNP levels is an accurate and rapid method that can aid in distinguishing between right heart failure and left heart failure.

Adsorption Removal of Sr by Barium Impregnated 4A Zeolite (BaA) From High Radioactive Seawater Waste (Barium이 함침된 4A 제올라이트 (BaA)에 의한 고방사성해수폐액에서 Sr의 흡착 제거)

  • Lee, Eil-Hee;Lee, Keun-Young;Kim, Kwang-Wook;Kim, Ik-Soo;Chung, Dong-Yong;Moon, Jei-Kwon;Choi, Jong-Won
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.14 no.2
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    • pp.101-112
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    • 2016
  • This study investigated the removal of Sr, which was one of the high radioactive nuclides, by adsorption with Barium (Ba) impregnated 4A zeolite (BaA) from high-radioactive seawater waste (HSW). Adsorption of Sr by BaA (BaA-Sr), in the impregnated Ba concentration of above 20.2wt%, was decreased by increasing the impregnated Ba concentration, and the impregnated Ba concentration was suitable at 20.2wt%. The BaA-Sr adsorption was added to the co-precipitation of Sr with $BaSO_4$ precipitation in the adsorption of Sr by 4A (4A-Sr) within BaA. Thus, it was possible to remove Sr more than 99% at m/V (adsorbent weight/solution volume)=5 g/L for BaA and m/V >20 g/L for 4A, respectively, in the Sr concentration of less than 0.2 mg/L (actual concentration level of Sr in HSW). It shows that BaA-Sr adsorption is better than 4A-Sr adsorption in for the removal capacity of Sr per unit gram of adsorbent, and the reduction of the secondary solid waste generation (spent adsorbent etc.). Also, BaA-Sr adsorption was more excellent removal capacity of Sr in the seawater waste than distilled water. Therefore, it seems to be effective for the direct removal of Sr from HSW. On the other hand, the adsorption of Cs by BaA (BaA-Cs) was mainly performed by 4A within BaA. Accordingly, it seems to be little effect of impregnated Ba into BaA. Meanwhile, BaA-Sr adsorption kinetics could be expressed the pseudo-second order rate equation. By increasing the initial Sr concentrations and the ratios of V/m, the adsorption rate constants ($k_2$) were decreased, but the equilibrium adsorption capacities ($q_e$) were increasing. However, with increasing the temperature of solution, $k_2$ was conversely increased, and $q_e$ was decreased. The activation energy of BaA-Sr adsorption was 38 kJ/mol. Thus, the chemical adsorption seems to be dominant rather than physical adsorption, although it is not a chemisorption with strong bonding form.

Composting of Compostable Wet Household Wastes Using Waste Newspapers as Humidity Amendment (수분개선제로 폐신문지를 이용한 가정쓰레기의 퇴비화)

  • Yun, Eun-Jin;Park, Ju-Won;Seo, Jeoung-Yoon
    • Korean Journal of Environmental Agriculture
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    • v.19 no.1
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    • pp.32-37
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    • 2000
  • Because the household garbage had high water contents, it is difficult to compost it without an additive. Therefore, this study was performed to investigate possibility of using the waste newspapers as a humidity conditioner for the household garbage composting. The maximum temperature was $66.0^{\circ}C$ in spring, $69.2^{\circ}C$ in summer, $60.9^{\circ}C$ in fall and $56.0^{\circ}C$ in winter for composting periods. The seasonal pH value reached around 8.5 after 1 week and then repeated fluctuation at the narrow range in spring and fall, while it was stabilized at the range of $8{\sim}9$ after increasing to 8.5 after 1 week in winter. The water content was reduced little in winter, while decreased significantly in the other seasons. The water content after 8 weeks was 22.2% in spring, 47.6% in summer, 25.5% in fall and 72.5% in winter. The mass was reduced rapidly during the first week of each season, but it did not show much decrease. The volume reduced after 8 weeks to 59%, 32%, 27%, and 34% in spring, summer, fall and winter respectively. Organic matter content decreased over the four seasons. Nitrogen contents were in the range of 0.7% to 2.2% during the four seasons. The contents of inorganic compounds based on dry matyter were in the range of $0.94{\sim}2.59%\;P_2O_5$, $1.23{\sim}1.87%\;CaO$, $0.37{\sim}0.46%\;MgO$, $0.55{\sim}1.98%\;K_2O$. Concentration of heavy metals(Hg, Cd, Pb, Cu, Cr, Zn, As) based on dry matter were less than the limiting value of the by-product compost.

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