• Title/Summary/Keyword: 폐전이

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Repeated Pulmonary Metastasectomy in Patients with Osteosarcoma (골육종 환자의 반복적 폐전이 절제술)

  • Lee, Jin-Gu;Shin, Kyoo-Ho;Park, In-Kyu;Chung, Kyung-Young;Song, Seung-Jun;Kim, Dae-Joon
    • Journal of Chest Surgery
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    • v.40 no.9
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    • pp.607-612
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    • 2007
  • Background: Surgical resection is a standard treatment for pulmonary metastases in patients with osteosarcoma, but the role of performing repeated resections is not clear. This study was designed to clarify the feasibility of performing a repeated pulmonary metastasectomy and the prognostic factors for pulmonary metastases in patients with osteosarcoma. Material and Method: Between January 1990 and July 2005, 62 patients with osteosarcoma were diagnosed with pulmonary metastases and 36 patients underwent pulmonary resection. We reviewed the patients retrospectively. Result: The total number of pulmonary metastasectomies was 62 in 30 patients. Among 36 patients, 18 had a second metastasectomy, 7 had a third metastasectomy, and one patient had a fourth metastasectomy. There was no distinctive difference between the first and second metastatectomy in terms of median survival time, and the 3-year and 5-year survival rate (first resection: 20.5 months, 32.0% and 29,4%; second resection: 11.3 months, 34.9% and 34.%). However, the median survival time (7.1 months) was shorter in patients with a third metastatectomy than in patients with one metastatectomy (p=0.01). In long-term survivors, the number of female patients, patients with a disease free time longer than 12 months, patients with a single metastasis and patients with anatomic resection was larger when compared to non-long term survivors, but showed no statistical significance. Conclusion: Repeated pulmonary metastasectomy is expected to prolong survival time in patients with osteosarcoma, and is expected to increase long-term survival in selected cases. Further studies with a large number of patients are necessary.

Surgical Treatment for Metastatic Pulmonary Sarcoma (폐전이 골 연부조직 육종에 대한 외과적 치료)

  • 박재길;이선희
    • Journal of Chest Surgery
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    • v.30 no.12
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    • pp.1214-1218
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    • 1997
  • The therapeutic results of pulmonary resection for metastatic bone and soft tissue sarcomas were analyzed. From 1986 to 1996, 14 patients(11 male and 3 female) underwent 15 pulmonary resections for metastatic sarcomas. One(7.1%) patient had 2 thoracotomies for recurrences. The number of metastatic tumors were from one to five. The primary malignant tumors were from bone in 4 and from soft tissues in 10. Mean survival time after thoracotomy was 29.2 months, and Kaplan-Meier's 5-year survival rate from the first metastasectomy was 33.2%. Three patients who had the tumor free interval period over 3 years were alive(mean survival period 52.6 months), whereas eleven patients of the less than 3 years were dead with disease(mean survival period 17.3 months). These results suggested that pulmonary. metastasectomy in bone and soft tissue sarcoma may prolong the survival rate.

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Spontaneous Regression of Extensive Pulmonary Metastasis of Benign Giant Cell Tumor of Bone - A Case Report - (자연 소실된 거대 세포종의 광범위한 폐전이 - 1예 보고-)

  • Park, Ru-Ppo;Lee, Sang-Hoon;Cho, Whan-Sung;Kim, June-Hyuk;Kim, Han-Soo
    • The Journal of the Korean bone and joint tumor society
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    • v.10 no.1
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    • pp.39-44
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    • 2004
  • A Giant cell tumor of bone has unusual characteristics of pulmonary metastasis as well as local aggressiveness. Clinical courses of pulmonary metastasis of benign giant cell tumor vary including rapid growth, continuously slow growth or spontaneous regression. We report a case of extensive pulmonary metastasis of giant cell tumor of bone, which regressed spontaneouly.

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The Effect of Transarterial Chemoembolization(TAE) on Lung Metastasis of Hepatocellular Carcinoma (간동맥 색전술이 간세포함의 폐 전이에 미치는 영향)

  • Lee, Heon-Ju;Eun, Jong-Ryul;Song, Young-Doo;Park, Chan-Won
    • Journal of Yeungnam Medical Science
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    • v.17 no.1
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    • pp.66-74
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    • 2000
  • Background: During the follow up period after transarterial embolization(TAE), cases of pulmonary metastasis were more prevalent in TAE-treated patients than in TAE-untreated patients. Therefore, a study was conducted to evaluate whether TAE increases the incidence of pulmonary metastasis of hepatocellular carcinoma and to clarify the risk factors for pulmonary metastasis. Methods: From March 1991 to March 1995, 156 patients who had been diagnosed with hepatocellular carcinoma by serology, and radiographic and histologic methods at Yeungnam University hospital were involved in this study. We excluded 12 patients with lung metastasis on initial diagnosis and the others. The remaining 144 patients had been followed up for at least 5 months and, divided into four groups according to lung metastasis and trans-arterial embolization treatment, and evaluated for age, sex, child-pugh score, liver cirrhosis, and level of AFP. Results: Pulmonary metastasis was found in 18.0% (26/144), of which 92.3%(24/26) and 7.7%(2/26) of the patients with and without transarterial chemoembolization, respectively. Of the patients, 23.5% (24/102) with TAE had lung metastais during follow-up periods and 4.7% (2/42) without TAE had lung metastasis. There was more likelihood for lung metastasis after TAE. but there was no difference between two groups in age, sex, child-pugh class, the presence of liver cirrhosis, and AFP. Conclusions: The incidence of pulmonary metastasis of hepatocellular carcinoma after TAE was higher. Child-pugh class was the only related clinical preciptating factors for pulmonary metastasis in TAE in our study. Our results suggest that regular chest X-ray check-ups may be more frequently needed by patients who had TAE treatment for hepatocellular carcinoma.

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Primary Leiomyosarcoma of the Left Lower Posterior Chest wall with Lung Metastasis - One Case Report - (폐 전이를 동반한 원발성 흉벽 평활근육종 - 1례 보고 -)

  • 김대현;김범식;박주철;조규석
    • Journal of Chest Surgery
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    • v.35 no.10
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    • pp.764-767
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    • 2002
  • An unusual case of primary leiomyosarcoma at the left lower posterior chest wall with metastasis to the right lung parenchyme is presented. The patient was a 43-year-old man who was asymptomatic but a slow growing hard mass was noted at the left lower posterior chest wall. The chest computed tomography showed a tumor at the left lower posterior chest wall with multiple metastasis to the right lung. The left lower posterior chest wall mass was examined by percutaneous needle aspiration and it was revealed as rhabdomyosarcoma histologically. En bloc resection to the left lower posterior chest wall tumor and metastasectomy to the multiple nodules in the right lung were done and pathological examination finally revealed primary leiomyosarcoma at the left lower posterior chest wall with multiple metastasis to the right lung. Chemotherapy was scheduled as adjunctive measure.

Solitary Pulmonary Metastasis of Gestational Choriocarcinoma -Three Cases of Different Types- (임신성 융모상피암의 고립성 폐전이 -3가지 유형-)

  • Yoo, Se-Hwa;Yoo, Zin-Mock;Cho, Jae-Yeon;In, Kwang-Ho
    • Tuberculosis and Respiratory Diseases
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    • v.39 no.1
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    • pp.79-82
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    • 1992
  • Gestational choriocarcinoma is a highly malignant tumor which arises from the trophoblast of human pregnancy. This tumor develops early pulmonary metastasis and the most common pattern of pulmonary metastasis is discrete multiple nodules. But occasionally solitary pulmonary metastasis occurs. Authors presented three cases of choriocarcinoma presented with different types of solitary pulmonary metastases with review of literatures. We emphasize the importance of careful obstetric history taking and screening of serum gonadotropin level in differential diagnosis of solitary pulmonary lesion especially among women who are from areas of high prevalence of trophoblastic neoplasia.

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Metastasising Recurrent Giant Cell Tumor - A Case Report - (폐 전이를 일으킨 재발성 거대세포종 - 증례 보고 -)

  • Kim, Tae-Seung;Park, Jun-Sic
    • The Journal of the Korean bone and joint tumor society
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    • v.7 no.2
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    • pp.73-79
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    • 2001
  • Giant cell tumor is usually found around the knee joint, especially in the distal femur or proximal tibia. Despite being classified as benign, it has unusual biological behavior of local aggressiveness and tend to have severely destructive lesion and develop rare pulmonary metastasis. Therefore, when the patient is presented to the physician with an expansile lytic lesion of challenging clinicopathologic entity extending to subchondral bone, the physician faces up to difficulties in treatment. We report a case of 25 years old patient having recurrent giant cell tumor in the right distal femur which developed metastasis to lung. The primary bone lesion was treated with local curettage and fillings with methylmethacrylate, but when he returned to the hospital two years later, the recurrence had developed with lung metastasis.

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Analysis of Surgical Results for the Patients with Pulmonary Metastasis from Colorectal Carcinoma (대장암의 전이성 폐암의 수술 결과에 대한 분석)

  • Sim, Hyung-Tae;Kim, Yong-Hee;Shin, Hong-Ju;Chun, Mi-Sun;Bae, Chi-Hoon;Lee, Eung-Sirk;Park, Seung-Il;Kim, Dong-Kwan
    • Journal of Chest Surgery
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    • v.39 no.11 s.268
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    • pp.838-843
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    • 2006
  • Background: The lung is the most common site of metastatic colorectal cancer comprising 10% of all curative resection of colorectal cancer. The reported 5 year survival rate varies among institutions. The purpose of the present study was to present the retrospective analysis of colorectal metastatic lung cancer surgery at our institution. Material and Method: A total of 61 patients undergoing surgery for metastatic colorectal lung cancer between July 1996 and December 2003 were included in the present study. The stage of the primary colorectal cancer, site of pulmonary metastasis, method of lung resection, the number and size of the metastatic nodules, the recurrence rate, and survival were assessed. Result: The 3 and 5 year survival rates were 66% and 41%, respectively. No significant risk factors were identified among the studied variables by either univariate or multivariate analysis. The mean disease free survival rate was 17 months. The most common recurrent site was lung, and among these patients, 3 underwent a second operation and two are still alive. Conclusion: The results of the above data suggest that pulmonary resection of metastatic lung cancer in select patients after curative resection of colon cancer may be a good therapeutic option with the potential for excellent results.

Benign Metastasizing Leiomyoma of Lung (폐로 전이된 양성 전이성 근종)

  • Cho Suk-Ki;Ryu Kyong-Min;Sung Sook-Whan;Chung Jin-Haeng;Lee Jae-Ho;Kim Young-Bum;Jheon Sang-Hoon
    • Journal of Chest Surgery
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    • v.39 no.4 s.261
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    • pp.335-339
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    • 2006
  • Benign metastasizing leiomyoma (BML) is a rare entity, characterized by the occurrence of multiple smooth muscle nodules in the lung with histologically benign leiomyoma, Both the uterine and pulmonary tumors have been found to express estrogen and progesterone receptors, which suggest that the pulmonary lesions represented metastases from leiomyoma. We experienced a 41-year-old female patient with BML and report here with the literature review.

Pulmonary Metastasectomy from Testicular Germ Cell Tumor - A case report- (고환에서 발생한 종자세포암의 폐전이 절제 - 1예 보고 -)

  • Cho, Jun-Woo;Park, Ki-Sung
    • Journal of Chest Surgery
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    • v.43 no.6
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    • pp.833-837
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    • 2010
  • This is a report of successful management for pulmonary metastasis following chemotherapy in patient with testicular germ cell tumor. Postchemotherapy PET-CT was not uptake FDG in metastatic lesion. Pulmonary metastasectomy was performed, which is important to manage a residual postchemotherapy lung mass in testicular germ cell tumor for histological correlation with primary testicular lesion to select the patients who require subsequent chemotherapy. Our patient was well 6 months after operation, not carried out chemotherapy because of no viable tumor.