Surgical Treatment for Metastatic Pulmonary Sarcoma

폐전이 골 연부조직 육종에 대한 외과적 치료

  • 박재길 (가톨릭대학교 의과대학 흉부외과학교실) ;
  • 이선희 (가톨릭대학교 의과대학 흉부외과학교실)
  • Published : 1997.12.01

Abstract

The therapeutic results of pulmonary resection for metastatic bone and soft tissue sarcomas were analyzed. From 1986 to 1996, 14 patients(11 male and 3 female) underwent 15 pulmonary resections for metastatic sarcomas. One(7.1%) patient had 2 thoracotomies for recurrences. The number of metastatic tumors were from one to five. The primary malignant tumors were from bone in 4 and from soft tissues in 10. Mean survival time after thoracotomy was 29.2 months, and Kaplan-Meier's 5-year survival rate from the first metastasectomy was 33.2%. Three patients who had the tumor free interval period over 3 years were alive(mean survival period 52.6 months), whereas eleven patients of the less than 3 years were dead with disease(mean survival period 17.3 months). These results suggested that pulmonary. metastasectomy in bone and soft tissue sarcoma may prolong the survival rate.

폐전이 골 연부조직 육종에 대한 폐절제 및 합병치료의 성적을 분석하였다. 1986년부터 1996년까지 14례 (남자 11례, 여자 3례)에서 15회의 폐절제술을 시행하였는데, 1례에서는 폐전이 육종의 재발로 2회의 폐절제술을 시행하였다. 절제된 폐전이 육종의 수는 1∼5개였다. 폐전이 육종의 병리조직학적 소견상 4례는 골육종 이었으며, 10례는 연부조직 육종이었다 폐절제술후 평균 생존기간은 29.2개월이었으며, Kaplan-Meier식에 의 한 5년생존율은 33.2%였다. 14례중 3례의 종양 자유기간이 3년이상으로 평균 생존기간은 52.6개월이었으며, 3년 이하의 11례는 추적기간중 모두 사망하여 이들의 평균 생존기간은 17.3개월이었다. 결론적으로 폐전이 육종에 대한 폐절제술은 뚜렷한 수명 연장 효과가 있을 것으로 생각된다.

Keywords

References

  1. J Surg Oncol v.47 no.1 Efficacy of pulmonary metastasectomy for recurrent soft tissue sarcoma Casson AG;Putnam JB;Natarajan G;Johnston DA;Mountain CF;McMurtrey M
  2. Cancer, Principle & practice of oncology(5th ed.) Metastatic cancer to the lung Pass HI;Donington JS;Devita VT(ed.);Hellman S(ed.);Rdsenberg SA(ed.)
  3. Cancer v.59 Thoracotomy for pulmonary metastatic osteosarcoma. An analysis of prognostic indicators of survival Meyer WH;Schell MJ;Kumar APM;Rao BN;Green AA;Champion J;Pratt CB
  4. Cancer v.55 Differing determinants of prognosis following resection of pulmonary metastases from osteogenic and soft-tissue sarcoma Putnam JB Jr;Roth JA;Wesley MN;Johnston MR;Rosenberg SA
  5. 대한정형외과학회지 v.30-4 악성 골 연부종양의 폐전이에 대한 수술적 치료 이수용;전대근;이종석;심영목;조재일;강용혁;정동환
  6. J Thorac Cardiovasc Surg v.87 Analysis of prognostic factors in patients undergoing resection of pulmonary metastases from soft tissue sarcomas Putnam JB Jr;Roth JA;Wesley MN;Johnston MR;Rosenberg SA
  7. Cancer v.72 Aggressive pulmonary metastasectomy for soft tissue sarcomas Ueda T;Uchida A;Komatsubara Y;Ono K
  8. Acta Orthop Scand v.66 no.6 Survival after pulmonary metastasectomy in soft tissue sarcoma Choong PFM;Pitchard DJ;Rock MG;Sim FH;Frassica FJ
  9. J Thorac Cardiovasc Surg v.97 no.5 Metastasectomy for soft tissue sarcoma. Further evidence for efficacy and prognostic indicators Jablons D;Steinberg SM;Roth J;Pittaluga S;Rosenberg SA;Pass HI
  10. Soft tissue sarcoma. Diagnosis and Treatment Surgical treatment of soft tissue sarcoma pulmonary metastasis Mountain CF;Raaf JH(ed.)
  11. J Surg Oncol v.56 Surgical treatment of pulmonary metastases from soft tissue sarcomas. A retrospective study in the Netherlands Van Geel A;Van Coevorden F;Blankenstein JD;Hoekstra HJ;Schuurman B;Bruggink EDM;Taat CW;Theunissen EB