• Title/Summary/Keyword: 폐경

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Effects of Porphyra tenera Extracts on Formation of Collagen Cross-link in Ovariectomized Rats (김 추출물이 갱년기 유도 흰쥐의 Collagen 가교형성에 미치는 영향)

  • 한희선;배송자;김미향
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.33 no.2
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    • pp.324-330
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    • 2004
  • The purpose of this study was to investigate the effects of Porphyra tenera (PT) extracts on formation of collagen cross-link in ovariectomized rats. From day 3 until 42 after the ovariectomy, Sprague-Dawley female rats were randomly assigned to the following groups : sham-operated rats (Sham), ovariectomized control rats (OVX-control), ovariectomized rats supplemented with PT at 50 mg/kg bw/day (OVX-PT5O), 200 mg/kgbw/day (OVX-PT200). The PT ethanol extracts were orally administrated 1 mL per day. Body weight gain, food intake and food efficiency ratio were significantly different among the groups. The change of collagen content was studied in lung, bone, cartilage and skin of ovariectomized rats. The effects of PT extracts on the amount of collagen were examined by measuring the hydroxyproline, which is a specific amino acid existing in collagen. Pyridinoline is pyridinium cross-link formed in the mature form of collagen from lysine and hydroxylysine residues. Pyridinoline content was analyzed by HPLC. Pyridinoline content in bone collagen was decreased by ovariectomy but supplementation with the PT extracts was similarly increased to Sham. These results suggest that the PT supplementation could decrease bone loss in postmenopausal women.

Pulmonary Infarction Associated with Fracture of Right Clavicle and Multiple Ribs (우측 쇄골 및 늑골골절과 동반된 폐경식 1례)

  • 김수성;이종임
    • Journal of Chest Surgery
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    • v.30 no.9
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    • pp.941-944
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    • 1997
  • Pulmonary infarction is rarely diagnosed with certainty except at postmortem examination. Part of this uncertainty is because of the inability to distinguish between hemorrhage, congestive a electasis, and necrosis clinically and radiographically. The pathogenesis of pulmonary infarction is poorly understood. It is dif%cult to induce pulmonary infarction in animals by ligation of the arterial supply to the lung. Many factors seem to be important in its pathogenesis, in addition to congestive heart failure, malignant tumor, thrombophlebitis, chronic obstructive lung disease, nephrotic syndrome, and postopeiative state. However, pulmonary infarction have not been reported in association with chest trauma. We report a case of pulmonary infarction associated with fractures of right clavicle and multiple ribs. A 45-year-old male had admitted due to right chest pain and dyspnea, which developed after right chest trauma occurred at about 3 weeks ago. He was treated at local clinics under the diagnosis of fractures of right clavicle and ribs until the admission. Chest CT disclosed a huge mass with central low density in right upper lobe, and small masses were also seen on both l ng fields. Open lung biopsy resulted in negativity for the malignancy. Clinical symptoms and radiological findings were not improved by conservative treatment. Right upper lobectomy was done eventually. The final diagnosis was pulmonary infarction. And, the patient has been well after operation.

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The Menopausal Age and Climacteric Symptoms, and the Related Factors of Korean Women (한국 여성의 폐경연령.갱년기 증상 관련요인)

  • Park, Young-Joo;Koo, Byoung-Sam;Kang, Hyun-Choel;Chun, Sook-Hee;Yoon, Ji-Won
    • Women's Health Nursing
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    • v.7 no.4
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    • pp.473-485
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    • 2001
  • This cross-sectional design was to identify the age at menopause of Korean women and the levels of bothersome menopausal symptoms. In addition, examining relationships between the levels of bothersome menopausal symptoms and sociodemographic factors, body mass index, menopause-related factors, and life-style behavior factors including smoking, alcohol use, physical activity, and diet was done. Two thousand eight hundred seven naturally postmenopausal women aged between 41-65 years were recruited by self-selection from 7 metropolitans and 6 provinces in Korea from Dec. 20, 1998 to April 30, 1999. The age at menopause of Korean women was 49.2 years(mean) and 50.0 years (median). The menopausal age of Korean women has slightly increased compared to a previous study. Based on the demographic factors, residential area and socioeconomic status were associated with the bothersome levels of climacteric symptoms. In the case of the life-style behaviors analysis, only alcohol use and a preference for wheat were associated with the bothersome levels of climacteric symptoms, especially physical symptoms.

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