• Journal of Periodontal and Implant Science
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• v.34 no.3
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• pp.671-681
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• 2004

Genomic Project 이후로 다양한 질환에 있어서 유전적인 영향에 관한 연구가 진행되고 있다. 이 연구의 목적은 한국인 치주질환 환자에서 Fc ${\gamma}R$ 유전자의 유전자다형성과 치주질환 특성과의 관련성을 알아보는 것이다. 치주적으로 건강한 한국인 90명(대조군, 남자64명, 여자26명), 중도 만성 치주염환자 40명(severe chronic periodontitis patients; severe CP, 남자 24명, 여자 16명)을 대상으로 임상지수(치주낭 깊이, 입상부착소실, 치은지수, 치태지수, 탐침 후 출혈지수, 치조골소실)를 측정하였다. 또한 이들의 정맥혈에서 추출한 DNA를 PCR(Polymerase Chain Reaction)법, 전기영동법 등을 이용하여 Fc ${\gamma}RIIIa$ , Fc ${\gamma}RIIIb$의 대립유전자의 존재여부를 확인하였다. 이를 바탕으로 각 유전자의 다형성 및 Fc ${\gamma}R$ 복합유전자형 (Fc ${\gamma}R$ composite genotype)을 확인하여, 각 군 간을 비교하였다. 치주질환의 특성과 유전자 다형성과의 관련성을 알아보기 위하여 Fc ${\gamma}R$ 유전자에 대한 유전자다형성을 조사한 결과 다음과 같은 결과를 얻을 수 있었다. 1. Fc ${\gamma}RIIla$에 대한 유전자다형성 연구결과 대조군과 severe CP, AgP군 사이에서, severe CP와 AgP군 사이에서는 대립유전자분포가 서로 유의성 있는 차이를 나타내었지만(p<0.05), Fc ${\gamma}RIIlb$에서는 유의성 있는 차이를 보이지 않았다(p>0.05). 2. Fc ${\gamma}R$ 복합유전자형간의 비교에서 유의성 있는 차이를 발견할 수 없었다(p>0.05). 이와 같은 결과를 종합하여 볼 때 실험대상 한국인 치주염환자에서 Fc ${\gamma}R$ 유전자에 대한 다형성분석에서 Fc ${\gamma}RIIIa$ 대립유전자가 치주염에 대한 감수성과 관련되어 있다고 생각된다. 이 연구의 결과는 유전자의 차이가 치주질환의 감수성 판단의 자료로 활용할 수 있는 가능성을 보여주고 있다.

• Journal of Periodontal and Implant Science
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• v.36 no.4
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• pp.839-847
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• 2006

The aim of this study is to monitor reporter gene expression under osteocalcin gene promoter, using a real-time molecular imaging system, as tool to investigate osteoblast differentiation. The promoter region of mouse osteocalcin gene 2 (mOG2), the best-characterized osteoblast-specific gene, was inserted in promoterless luciferase reporter vector. Expression of reporter gene was confirmed and relationship between the reporter gene expression and osteoblastic differentiation was evaluated. Gene expression according to osteoblstic differentiation on biomaterials, utilizing a real-time molecular imaging system, was monitored. Luciferase was expressed at the only cells transduced with pGL4/mOGP and the level of expression was statistically higher at cells cultured in mineralization medium than cells in growth medium. CCCD camera detected the luciferase expression and was visible differentiation-dependent intensity of luminescence. The cells produced osteocalcin with time-dependent increment in BMP-2 treated cells and there was difference between BMP-2 treated cells and untreated cells at 14days. There was difference at the level of luciferase expression under pGL4/mOGP between BMP-2 treated cells and untreated cells at 3days. CCCD camera detected the luciferase expression at cells transduced with pGL4/mOGP on Ti disc and was visible differentiation-dependent intensity of luminescence This study shows that 1) expression of luciferase is regulated by the mouse OC promoter, 2) the CCCD detection system is a reliable quantitative gene detection tool for the osteoblast differentiation, 3) the dynamics of mouse OC promoter regulation during osteoblast differentiation is achieved in real time and quantitatively on biomaterial. The present system is a very reliable system for monitoring of osteoblast differentiation in real time and may be used for monitoring the effects of growth factors, drug, cytokines and biomaterials on osteoblast differentiation in animal.

• Journal of Periodontal and Implant Science
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• v.39 no.4
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• pp.407-412
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• 2009

Purpose: This study was performed to evaluate the effect of powered toothbrush with a wireless remote display on the subjective and objective oral hygiene improvement. Methods: One hundred and fifteen subjects in healthy or mild gingivitis status between the ages of 20 and 90 were recruited and reviewed for study inclusion criteria. At first visit, 115 pre-screened subjects filled in the questionnaire form which consisted of demographic factors, behavioral factors (smoking, alcohol consumption), toothbrushing habits (brushing time and frequency), self-reported oral health status, and self-satisfaction. Baseline clinical indices (Plaque index, Gingival index) were also recorded by a periodontist. Subjects were instructed how to use powered toothbrush with a wireless remote display, and were provided with it. Thirty days after first visit, 90 subjects returned for the second assessment by self-reported questionnaire form and professional clinical checkup. Statistical analysis was performed using paired t-test for the difference between baseline and second visit data. The relationship among variables was examined with chi-square test and Fisher' s exact test. Results: Significant differences were not found on self-reported satisfaction related with sex, smoking, alcohol consumption (P<0.05). Self-reported tooth brushing habit was improved in the aspect of brushing time and frequency. Significant differences were found on the self-reported oral health status, self-satisfaction, and clinical indices between the baseline and second visit data (P<0.01). Clinical indices were significantly reduced after using powered toothbrush with a wireless remote display (P<0.01). No adverse reactions were reported during the study period. Conclusions: Powered toothbrush with a wireless remote display successfully promoted oral hygiene from the subjective and objective viewpoint after 30 days of home usage.

• Journal of Periodontal and Implant Science
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• v.38 no.2
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• pp.135-142
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• 2008

Purpose: Numerous studies have shown that crestal bone resorption around the implant was related to the location of the implant abutment junction(IAJ). Recently it was hypothesized that platform switching termed the inward horizontal repositioning of the IAJ might limit bone resorption around the implants. The purpose of this clinical study was to evaluate the effect of platform switching on crestal bone resorption. Materials and Methods: The crestal bone loss of 65 external hex implants in 26 patients were radiographically measured at crown placement and follow-up examinations. 23 standard implants(non-platform switching group, NP) were connected with the matching abutments and 42 wide implants(platform switching group, PS) were connected with the 1 mm smaller diameter abutments. Results: There was significant difference of crestal bone loss between NP group and PS group. For implants in the NP group, mean crestal bone loss was $1.18{\pm}0.68\;mm$ at crown placement and $1.42{\pm}0.41\;mm$ at follow-up. The meal bone loss in PS group was $0.47{\pm}0.52\;mm$ at crown placement and $0.60{\pm}0.65\;mm$ at follow-up. When the crestal bone changes according to placement depths of implants were compared, subcrestal position of IAJ had a significantly less bone loss in PS group, but it was not in NP group. Conclusion: Within the limits of the present study, it was concluded that platform switching technique might decrease crestal bone loss around the implants. Additionally, when the IAJ of implant was placed 1 mm deeper in the alveolar bone, the effect of platform switching on bone loss was enhanced.

• Journal of the korean academy of Pediatric Dentistry
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• v.30 no.4
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• pp.678-683
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• 2003

Preschool children in Iksan city, 3-5 years old, were examined for their prevalence of severe early childhood caries. The case definition was 1 or more cavitated, filled, or missing (due to caries) smooth surfaces in primary maxillary anterior teeth. Feeding behavior and oral hygiene behavior were investigated by a questionnaire. The prevalence was 20.8% for 36-47 months, 23.6% for 48-59 months, and 30.8% for 60-71 months. Going to sleep with bottle beyond 1 year (P<0.05), immediate removal of bottle after child fell on sleep (P<0.01), beginning time of toothbrushing (P<0.01) had significant relationship with the prevalence of severe early childhood caries. Toothbrushing frequency of primary care provider and use of oral cleaning aids by primary care provider had a tendency to be related with the prevalence(P<0.10).

• Journal of Korean Society of Forest Science
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• v.88 no.1
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• pp.117-123
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• 1999

Consumer surplus is to be a value concerning a time horizon. Especially it is very important how long time horizon would be chosen in contingent market. This study aimed to provide causes of difference recreation benefits through discount rate in many aspects. The data were collected by personal interviews with visitors in Songnisan National Park. The respondents answered yes or no, dichotomous choice, on recreation benefits according to a chosen time horizon, one year or five years. The probit model was used in the analysis. In order to avoid the truncation bias of upper bound, the median was chosen as the recreation benefits of visitor. As the result, the value was evaluated to be 16,569 Won for one year and 27,111 Won for five years. The discount rate is estimated 153% annually to coincide different recreation benefits. The reasons of the high discount rate were to be interpreted as following five types : (1)uncertainty of future consumption (2)increasing of probability of the substitution owing to increasing of time horizon (3)recognization of different time horizons (4) effect by the price ratio of goods and utility function (5) overestimation of the recreation benefits owing to a basic premium of payment vehicle.

• Journal of the Korean Geographical Society
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• v.51 no.3
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• pp.441-454
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• 2016

This study deals with the contemporary rural housing with special reference to the roof types/materials and the outer wall materials in Ulleungdo Mountains. The most frequent roof type of rural housing is the hip-and-gable roof type(42.1%); and the next, the gable roof type(25.8%). For the roof materials, the precoated steel plate(69.1%), the asphalt shingle(11.8%), and the cement(10.7%) are the most frequent but the roofing tile and the artificial slate are not used. And for the outer wall materials, the cement(27.5%), the siding(21.3%), the corrugated galvanized iron(16.8%), and the lumber sheet(6.7%) are the most frequent. It is the hip-and-gable roof housing type with the precoated steel plate(roof materials)(41%), or the hip-and-gable roof housing type with the precoated steel plate(roof materials) and the cement(outer wall material) (18.0%) that is the most frequent type of rural housing in Ulleungdo Mountains. For the roof/wall materials, the ratio of the corrugated galvanized iron is high probably due to the relatively low cost of transport, and the ratio of the roofing tile, the artificial slate, the red brick, and the building stone is very low probably due to the relatively high cost of transport.

• Journal of Korean Home Economics Education Association
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• v.19 no.4
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• pp.257-271
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• 2007

This study examined students' satisfaction with cyber education focused on the sections of consumer education in the University. The sample of this study was 94 students taking a 'Consumer Policy & Education' cyber course. The data were collected using structured questionnaires and analysed by descriptive statistics, frequency, percent, mean, SD, t-test and one-way ANOVA with Duncan test. The results of this study were as follows: First, the reason students took a cyber course was that it was easy to manage the course under "self-control". Second, they studied an average 1-2 hours for a one unit lecture at home on weekdays between 9 p.m. and midnight. Third, the students' satisfaction with cyber education showed a slight preference for the web based environment as opposed to the online lessons. Fourth, the biggest problem with taking a cyber course was that the students found it difficult to concentrate well on the lecture.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2018.10a
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• pp.590-592
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• 2018

Taxis that are illegally parked on the road to catch customer can cause traffic congestion and sometimes cause traffic accidents. Stop position of taxis is determined by the long term experience of taxi drivers. In this study, We provide information to taxi drivers and customer who visit in first time through finding stop position of taxis by time. To do this, we used the Internet of Vehicle (IoV) data collected from sensors installed in 40 taxis. Previous studies attempted by forming a cluster around a taxi. Since this method is centered on a taxi, the position of the cluster changes depending on the location of the taxi. In this study, we use a road segmentation algorithm to solve these problems. Unlike the previous studies, since the cluster is formed around the road, the position of the cluster is fixed and it is not affected by the number of taxis, so it is possible to grasp the stop position in real time. The road segmentation is made up of 30m units, and map the taxi location data divided into hourly, weekday, and weekend to the nearest point. As a result of the mapping, it was difficult to see a big difference in the time of week because there were few taxis to operate on weekends, but in case of weekdays, the difference of stop position between the commute time zone and the night time zone was confirmed. The results of this study suggest that it will be possible to propose the prevention of taxi illegally driving taxi and the location of the taxi stand.

• Korean Journal of Environment and Ecology
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• v.31 no.1
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• pp.104-111
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• 2017

The construction of road tunnels and bridges have delivered driving efficiency and stability based on developed engineering technology. Tunnels have the advantage of reducing the deforested area compared with other road construction methods. Since a tunnel is an underground passageway dug through the surrounding soil/earth/rock and enclosed except for the entrance and exit, commonly at each end, it does not cause a large amount of deforestation. This study surveyed the deforested areas at each end of the tunnel by the design of the tunnel entrance and exit and forest topography to minimize the amount of deforestation caused by road construction. A survey was done on a total of 150 tunnels (300 entrances and exits) on several main roads in Korea. The deforested area of each tunnel was collected by a breakdown of the entrance area and the upper area of the tunnel. According to the results of Kruskal-Wallis analysis, it was found that there was statistically a significant relation between the location of tunnels and the amount of deforestation by the topographical access type of the tunnels. The tunnel with 'facing orthogonal to incline' type access caused the smallest deforestation while the the tunnel with 'facing to valley' and 'parallel with incline' type accesses caused large deforestation during tunnel construction. Tunnel positioning in the light of topography can reduce the deforested area by up to 1.5ha at each tunnel.