• Title/Summary/Keyword: 편도 하부 영역

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Characteristics of Intrinsic Functional Connectivity of Amygdalar Subregions in Social Anxiety Disorder (사회불안장애에서 편도 하위영역의 내재 기능적 연결성의 특성)

  • Kim, Jinseong;Yoon, Hyung-Jun;Park, Sunyoung;Shin, Yu-Bin;Kim, Jae-Jin
    • Anxiety and mood
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    • v.10 no.1
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    • pp.44-51
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    • 2014
  • Objective : The amygdala has been considered to be a critical region in the pathophysiology of social anxiety disorder, but subregional connectivity pattern has not been examined yet despite lots of previous functional neuroimaging studies. Methods : Resting-state functional magnetic resonance imaging data was obtained in 19 patients with social anxiety disorder and 20 normal controls, and default mode functional connectivity with each of basolateral, centromedial and superficial areas of the amygdala was measured and compared between the two groups. Results : Differential amygdala-based networks between the two groups were distributed to all over the brain. In particular, however, a bias on the amygdala-cingulate pathway was observed in the superficial amygdala only. Connectivity strengths between the superficial amygdala and perigenual anterior cingulate cortex were correlated with scores of social interaction and avoidance. Conclusion : Our findings provide new insights into understanding of the intrinsic cognitive bias model of social anxiety disorder. An abnormality in superficial amygdala-anterior cingulate connectivity may influence on cognitive processing of socially-relevant information in social anxiety disorder.

AN EXPERIMENTAL STUDY ON TRACHEAL RECONSTRUCTION USING RIB CARTILAGE AND PERICHONDRIUM IN RABBITS (가토의 자가 늑연골 및 늑연골막을 이용한 기관재건술에 대한 실험적 연구)

  • 채우석;김경래;이형석;안경성;김선곤
    • Proceedings of the KOR-BRONCHOESO Conference
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    • 1991.06a
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    • pp.24-24
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    • 1991
  • 기관협착증은 이비인후과 영역에 있어서 치료가 어려운 질환중의 하나로 이의 재건에는 여러가지 자가조직이 각각의 장점에 따라 사용되어 왔지만 완전하고 만족할만한 결과를 얻지 못하는 실정이다. 저자들은 가토의 자가 늑연골 (1군) 및 늑연골막 (2군)을 이용한 기관 재건술을 시행하여 다음과 같은 결과를 얻었다. 1) 이식편은 술후 10주 (1군) 및 12주 (2군)에 흡수나 섬유조직으로의 대치는 없었으며, 기관강의 크기는 직상 하부의 정상기관과 큰 차이가 없었다. 2) 늑연골을 이식한 부위는 연골막의 내세포층에서 연골세포가 분화, 이동되어 절단된 연골사이로 이동하여 새로운 연골을 형성하였다. 3) 늑연골막을 이식한 부위는 연골막에서 형성된 연골세포 및 연골기질이 절단된 연골사이로 이동하여 새로운 연골을 형성하였다. 4)) 이식한 부위의 점막층은 점막재생이 이루어져 원주상피로 피복되었다. 5) 기관 전벽의 결손부위는 늑연골 및 늑연골막을 이용하여 성공적으로 재건되었다.

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Relationship between Preschool Child-Mother Interaction, Child's Health Status, Health-Related Quality of Life, and Social Development (학령전기 아동과 어머니의 상호작용, 아동 건강 상태, 건강 관련 삶의 질 및 사회적 발달 간의 관계)

  • Park, Sunghee
    • Child Health Nursing Research
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    • v.20 no.4
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    • pp.255-263
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    • 2014
  • Purpose: The purpose of this study was to examine relationship of preschool child and mother interaction, child's health status, health-related quality of life and social development. Also, it was intended to provide a basis for development of mother-child interaction programs. Methods: The present study was a descriptive research. Participants in this study were a convenience sample of 230 preschool children and their mothers. For the final analysis 209 questionnaires were used after eliminating questionnaires with incomplete responses. Data were analyzed using the SPSS 18.0 program. Results: The mean score for interaction between preschool child and mother was $3.96{\pm}0.55$ out of 5 points, for child health status, $3.75{\pm}0.62$ out of 5 points, for child's health-related quality of life, $83.89{\pm}10.20$ out of 100 points and for child's social development, $19.66{\pm}3.57$ out of 24 points. Positive correlations were found between interaction of preschool child and mother, child's health status, health-related quality of life, and social development. Conclusion: The results demonstrate the importance of the quality of the relationship between mother, the child's primary caregiver, and her child for the healthy growth and development of preschool children. It is suggested that intervention programs for preschool child-mother interaction should be developed using evidence based data.

Activation of Limbic Area due to Oxygen Administration during Visuospatial Task (공간 과제 수행 시 고농도 산소 공급에 의한 변연계 활성화에 관한 연구)

  • Choi, Mi-Hyun;Lee, Su-Jeong;Yang, Jae-Woong;Kim, Ji-Hye;Choi, Jin-Seung;Tack, Gye-Rae;Chung, Soon-Cheol;Kim, Hyun-Jun
    • Science of Emotion and Sensibility
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    • v.12 no.4
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    • pp.443-450
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    • 2009
  • The purpose of this study is to observe activation of limbic system during performing visuospatial tasks by 21% and 30% oxygen administration. Eight right handed male college students were selected as the subjects for this study. A visuospatial task was presented while brain images were scanned by a 3T fMRI system. The experiment consisted of two runs: one was a visuospatial task under normal air(21% oxygen) condition and the other under hyperoxic air(30% oxygen) condition. The neural activations were observed at the limbic system which is seperated 8 regions such as cingulate gyrus, thalamus, limbic lobe, hypothalamus, hippocampus, parahippocampa gyrus, amygdala, and mammiilary body. By two oxygen levels, activation areas of limbic system are almost identical. Increased neural activations were observed in the cingulate gyrus and thalamus with 30% oxygen administration compared to 21% oxygen. During 30% oxygen administration, improvement of visuospatial task performance has a relation to increase of neural activation of subcortical structures such as thalamus and cingulate gyrus as well as cerebral cortex.

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A Development of Seepage Analysis Model for Unsaturated Soil during Rainfall (강우시 불포화지반의 침투해석모형 개발)

  • Lee, Jung-Sik;Han, Heui-Soo;Jang, Jin-Uk
    • Proceedings of the Korea Water Resources Association Conference
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    • 2009.05a
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    • pp.796-800
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    • 2009
  • 토목구조물 및 사면의 붕괴는 집중호우가 내리는 경우 많이 발생하고 있으며, 특히 사면에서는 붕괴까지의 변형이 급속히 진행되어 이를 사전에 예방하기는 매우 어려운 현실이다. 침투 및 배수과정에서의 사면 붕괴는 강우침투로 인한 지반의 물리적 특성변화가 직접적으로 사면의 안전계수 변화에 영향을 주는 것으로 판단되며, 이때 발생하는 물리적 특성변화로는 침투시 사면 내 지반의 단위 중량은 증가하여 전단응력의 증가 및 전단강도 감소현상이 발생하며, 이와 반대로 사면 내 배수로 인하여 전단응력의 감소 및 전단강도의 증가현상이 발생한다. 따라서 본 연구에서는 강우침투로 발생하는 지반의 포화도 변화를 지반 내 투수계수의 함수로 설명하여 강우로 인한 지반의 침투 및 배수과정을 규명하고자 한다. 일반적으로 지반 내 지하수의 침투과정은 라플라스 공식을 적용한다. 그러나 라플라스 공식은 정상 상태(Steady State)일 경우에만 사용할 수 있고, 강우 등으로 인한 지하수의 수두 변화가 발생한 비정상 상태(Unsteady State)의 경우에는 부적합하므로 사면과 옹벽 등의 토질구조물에서는 안전성 변화를 계산할 수 없다. 이를 위해 사면 내 지반의 침투 및 배수과정을 투수계수의 함수로 나타내어, 강우의 침투과정을 Fourier Series, 변수분리법 및 섭동함수를 사용하여 식으로 유도함으로서 강우에 의한 지반의 침투 및 배수과정에 따른 사면 내 지하수의 분포를 예측한다. 침투과정 해석을 위하여 지표에서 포화대까지의 깊이 10m의 모델사면 및 지표부터 포화대까지의 포화도는 직선으로 비례한다는 가정을 적용한다. 먼저 푸리에 급수를 이용, 시간에 따른 온도를 열전달에 관하여 편미분하여 발생하는 열확산계수를 투수계수로 변환함에 따라 지하수의 시간과 수직방향거리에 대한 지반의 포화도를 산정한다. 변수분리법은 산정된 포화도에 지반의 초기조건과 경계조건를 고려하기 위해 적용하며, 변수분리법에 의해 산정된 지하수 분포를 섭동함수법으로 과도 및 정상상태로 분류한다. 본 연구의 수행으로 인해 얻어진 결과를 요약하면 다음과 같다. 첫째, Fourier Series와 변수분리법, 섭동함수를 이용하여 강우에 의한 지반의 포화도 변화를 수식적으로 나타낼 수 있으며 둘째, 지반에서의 강우침투과정을 식으로 표현함으로서, 깊이별 시간에 따른 포화도의 영역이 상부로부터 하부로 전이되는 과정을 알 수 있다. 셋째, 푸리에 급수를 이용한 지반의 침투계산으로 강우로 인한 지반의 포화영역 및 불포화영역을 명확히 구분할 수 있으며, 각 깊이별 포화도를 계산하여 각 구간에서 불포화구간의 전단강도에 대한 보다 정확한 계산이 가능하리라 판단된다.

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Development of Automated Nondestructive Inspection System for BMI Nozzles in Nuclear Vessel (원자로 BMI 노즐 검사를 위한 자동화 비파괴검사 시스템 개발)

  • Park, Joon Soo;Lee, Won Kun;Han, Won Jin;Lee, Sun Ho;Seong, Un Hak
    • Journal of the Korean Society for Nondestructive Testing
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    • v.33 no.1
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    • pp.26-33
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    • 2013
  • BMI nozzles in bottom head of the nuclear vessel are one of major components in nuclear power plants. The BMI nozzles have high possibility to generate PWSCC(primary water stress corrosion crack) according to recent foreign case although operation temperature is lower then the upper head of the nuclear vessel. Thus, nondestructive inspection of the BMI nozzles is required. But, inspection of BMI nozzles is not easy since the BMI nozzles placed in high radiated area and inside the nozzles filled with boric acid. Thus, in this study, a TOFD transducer for inspection of BMI and automated scanner system with water were developed. Also, validation of performance of the developed transducer and system are performed using specimens with artificial defects.

Neurobiology of Leptin : Neuroendocrine Regulation of Food Intake (Leptin의 신경생물학 : 섭식의 신경내분비 조절)

  • Kim, Seung-Hyun;Joe, Sook-Haeng
    • Korean Journal of Psychosomatic Medicine
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    • v.7 no.2
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    • pp.149-157
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    • 1999
  • Food intake and body weight are determined by a complex interaction of regulatory pathways. Leptin, the product of the ob gene, is a recently discovered hormone secreted by adipocytes, that signals the amount of adipose tissue energy stores to the brain and exerts major effects on energy homeostasis and neuroendocrine function. In addition, leptin has recently been shown to affect reproductive function in rodents and humans. The study of leptin and its effectors in the hypothalamus may provide important insights with respect to the interplay of several hypothalamic neuropeptides in regulating feeding as well as the interaction of genetics and environment in the regulation of energy homeostasis. In this review we summarise the action of leptin in the regulation of food intake and highlight a working model of the effects of environmental factors on the leptin system.

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Health Literacy in the Korean Elderly and Influencing Factors (한국 노인의 건강 문해(Health Literacy)실태와 영향 요인 -인구사회학적 특성을 중심으로-)

  • Lee, Tae Wha;Kang, Soo Jin
    • 한국노년학
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    • v.28 no.4
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    • pp.847-863
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    • 2008
  • This study aimed to measure the health literacy among Korean elderly living in the community, and to explore the factors influencing health literacy of the elderly. A descriptive correlational research design was used. The sample consisted of 411 elders who were conveniently selected from the community welfare center users in Seoul and Gyeong-gi province. Data were collected from face-to-face interviews by trained interviewers between January, 7 and February, 4, in 2008. Health literacy was measured by Korean Health Literacy Scale developed by Lee(2008). Descriptive statistics, ANOVA, t-test, and multiple regression were used to analyse the data. In result, the mean score of health literacy was 17.46(${\pm}5.73$) with a range of 0 to 25, 42.8% of elderly had limited health literacy problems. Multiple regression showed that 26.5% of variance in health literacy was accounted for by the combination of education, age, living arrangement, and income. In conclusion, various strategies to improve health literacy in elderly population in the areas of health education and disease management should be needed to reduce health disparities among elderly.

Relationship of Nutritional Knowledge, Dietary Self Efficacy and Change of Dietary Behavior of Nutrition Professional (영양전공자의 영양지식, 식이 효능감, 식행동 변화간의 관련성)

  • Kwon, Seon-Young;Han, Jang-Il;Chung, Young-Jin
    • Journal of Nutrition and Health
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    • v.41 no.6
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    • pp.550-560
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    • 2008
  • The purpose of this study is to investigate the relationship of nutritional knowledge, dietary self-efficacy and dietary behavior of nutritionist. Total 190 dieticians of middle and high schools in Daejeon metropolitan city(44.2%) and Chungnam area(55.8%) were surveyed by questionnaires. The change of dietary intakes was used as an index of dietary behavioral change, and dietary self-efficacy are categorized into 4 sub groups of general dietary habit, choice of food, environmental stimulus and emotional conditions. Overall nutritionl knowledge of school dieticians was relatively high as 80.3 score, but specific and detail knowledge about food and nutrition yet have to be strengthened. Dietary self-efficacy of 'choice of food' was the highest with 85.4 and self-efficacy of 'environmental stimulus' was the lowest with 69.7 in the subjects. There was no influence between nutrition knowledge and dietary self-efficacy of school dieticians. According to the level of dietary self-efficacy, the intake of desirable food showed no significant difference, but the intake of undesirable foods decreased as dietary self-efficacy increased(p<0.001). In the analysis of correlation of change in intake of desirable and undesirable foods with nutrition knowledge and 4 different variables of dietary self-efficacy, a nutrition knowledge variable did not show any correlation with other variables. While, total dietary self-efficacy or each 4 sub items showed negative correlation with the intake of undesirable foods. And all 4 sub items of dietary self-efficacy could be the principal factors to constrain the intake of undesirable foods, but 2 items of dietary habits and emotional condition of 4 sub items are the factors to increase the intake of desirable food. Accordingly, it is suggested that dietary self-efficacy could be a powerful factor to induce the behavioral change of professional dieticians.

The effect of rearing, health and nutrition intervention services on grandparents-grandchildren families in a rural Korean area (농촌 조손가정의 양육, 건강 및 영양중재서비스의 효과)

  • Cho, Young-Hyang;Park, Yoon-Chang
    • Journal of agricultural medicine and community health
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    • v.35 no.3
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    • pp.274-286
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    • 2010
  • Objectives: The purpose of this study was to examine the effects of the rearing, health and nutrition services through intervention in GP-GC (grandparents-grandchildren) families. Methods: A structured questionnaire was administered in January 2008 and January 2009 to 55(70) grandparents of GP-GC families who received intervention services also GP-GC families that did not receive services. The study area was the city of Chunnam Province, South Korea. The intervention services were provided by electronic voucher one day per week. The questionnaire assessed the general characteristics of the grandparents, childcare stress and burden, health status (ADL, IADL, depression, subjective health status and fall index) and mini nutritional assessment(MNA). The data were analyzed using SPSS software and an F-test, Chi-squared test and t-test. Results: The stress of grandparents resulting from childcare was high, but depression in grandparents perceived by grandchildren was significantly lower in served GP-GC families than in non-served GP-GC families. Differences in scores of affection (t=2.12, df=116, p<.05), automatics (t=2.92, df=116, p<.01), realistic(t=2.24, df=116, p<.05), and level of depression(t=2.90, df=116, p<.01) were significant. Incidences of acute disease, IADL cognitive fuction and depression of grandparents were slightly higher. Intervention services for GP-GC families had an impact on the childcare attitude and health status of grandparents. The intervention services of nutrition for grandparents were not promoted, but the scoring for subjective nutrition status were statistically higher for the served group (t=18.230, p<.0001). Conclusions: This study found that intervention programs of childcare services and health and nutrition management are effective for grandparents of GP-GC families. Intervention services for GP-GC family should establish the political issue.