• Title/Summary/Keyword: 특발성

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Surgical Treatments and Clinical Outcomes for Idiopathic Osteoarthritis of the Tarsometatarsal Joints (족근 중족 관절의 특발성 골관절염에 대한 수술적 치료 및 임상적 결과에 대한 분석)

  • Jung, Hong-Geun;Byun, Woo-Sup;Myerson, Mark S.;Schon, Lew C.
    • Journal of Korean Foot and Ankle Society
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    • v.8 no.1
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    • pp.31-38
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    • 2004
  • Purpose: The purpose of the study was to identify the subtypes of idiopathic osteoarthritis of the tarsometatarsal joints based on accompanying hindfoot, midfoot, or foot deformities and their corresponding surgical options and also to evaluate the overall clinical results. Materials and Methods: The study included 59 patients (67 feet) with idiopathic tarsometatarsal joint osteoarthritis. Tarsometatarsal fusion was performed for tarsometatarsal joint and accompanied secondary change was divided into subtypes and various bony reconstruction was carried out. The patients were evaluated with the AOFAS midfoot score and FFI. The average patient age was 60.2 years with 40.6 months follow-up. Fifty-four feet (80.6%) had been treated with realignment fusion. Twenty-six feet had first and second tarsometatarsal joint fusion, and 20 feet had first tarsometatarsal fusion only. Six subtypes were identified based on associated foot deformities: 1) in-situ without deformities (18%), 2) pes planovalgus (45%), 3) rockerbottom (15%), 4) cavus foot (1%), 5) hallux valgus (12%), and 6) hallux valgus with pes planovalgus or rockerbottom (9%). Plantar-medial closing-wedge resection was used in 10 feet to correct rockerbottom. For pes planovalgus, a medial sliding calcaneal osteotomy was done. Lateral column lengthening with medial sliding calcaneal osteotomy was done for severe pes planovalgus, and triple arthrodesis was done for rigid pes planovalgus. Hallux valgus was corrected with the Lapidus procedure (85.7%). Results: AOFAS midfoot scores improved from preoperative 34.1 points to postoperative 83.9 points (p<0.05). The Foot Function Index postoperatively also showed significant improvement (p<0.05), with a high satisfaction rate (86.6%). There were 29 complications, most commonly sesamoid pain. Conclusion: Idiopathic tarsometatarsal OA feet can be classified into six categories. Pes planovalgus feet should be treated with medial sliding calcaneal osteotomy, lateral column lengthening, or triple arthrodesis in addition to tarsometatarsal joint realignment fusion. Rockerbottom and hallux valgus deformities should also be addressed.

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Lung Cancer Presented as Painful Swelling of Lower Legs (하지의 통증 및 부종을 주소로 내원한 환자에서 발견된 폐암1예)

  • An, Jin Young;Lee, Jang Eun;Park, Hyung Wook;Lee, Jeong hwa;Yang, Seung Ah;Park, Young Kun;Lee, Sang Rok
    • Tuberculosis and Respiratory Diseases
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    • v.61 no.4
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    • pp.398-402
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    • 2006
  • Trousseau's syndrome comsists of migratory thrombophlebitis and thromboembolic disorders of the venous and arterial systems in a malignancy or occult cancer. The overall incidence has been reported to vary from 1 to 11%. Pancreatic, lung, prostate, and stomach cancer is associated with the greatest risk of thromboembolic events. We encountered a 49-year-old man who presented with painful swelling of his lower legs. The chest radiograph showed increased opacity of the Left middle lung fields and Doppler sonography showed a thrombus in the left superficial femoral vein. Chest Computed Tomography showed a 5cm sized left hilar mass invading the pericardium with lymphadenopathy. The bronchoscope biopsy demonstrated an adenocarcinoma of the lung. Platinum based chemotherapy and anticoagulant therapy with warfarin was carried out. The patient was later discharged with an improvement in the painful swelling of his lower legs.

A Case of Idiopathic Pulmonary Alveolar Proteinosis Treated with Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) after Partial Response to Whole Lung Lavage (전폐 세척술로 부분 관해 후 GM-CSF 투여로 치료된 특발성 폐포단백증 1예)

  • Song, Jun Whi;Park, Sun Hyo;Kang, Kyung Woo
    • Tuberculosis and Respiratory Diseases
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    • v.67 no.6
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    • pp.569-573
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    • 2009
  • Idiopathic pulmonary alveolar proteinosis (PAP) is a rare disorder characterized by surfactant component accumulation in the alveolar space. Idiopathic PAP has recently been recognized as a autoimmune disease of impaired alveolar macrophage function caused by autoantibodies against granulocyte-macrophage colony-stimulating factor (GM-CSF). While whole lung lavage has been the standard treatment, not every patient shows a complete response. Subcutaneous injection or inhalation of GM-CSF is another promising treatment option for PAP. A 45-year-old patient visited our hospital for dyspnea, he was diagnosed as PAP and underwent whole lung lavage. Eighteen months later, the patient had not achieved complete remission in despite of initial response. After then he was administered with GM-CSF (5 ${mu}g/kg/day$, subcutaneous injection) for fivetimes a week during 2 months. Nine months later, the abnormal shadows in high-resolution computed tomography (HRCT) decreased and the patient fully recovered in forced vital capacity. After 60 months, the HRCT scan showed complete remission of PAP.

The Effect of Steroid Therapy for Idiopathic Unilateral Vocal Cord Palsy (특발성 일측성 성대마비에서 경구 스테로이드 요법의 효과)

  • Bae, Jong-Won;Lee, GilJoon
    • Journal of the Korean Society of Laryngology, Phoniatrics and Logopedics
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    • v.30 no.2
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    • pp.107-111
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    • 2019
  • Background and Objectives Idiopathic unilateral vocal fold paralysis (IVFP) is believed to be due to inflammation and edema of the recurrent laryngeal nerve caused by viral diseases such as upper respiratory tract infections. Corticosteroid has a potent anti-inflammatory action which should minimize nerve damage. The purpose of this study was to investigate the effect of oral steroid therapy on IVFP. Materials and Method Study was performed for the IVFP patient from January 2012 to August 2017. Patient's dermography, direction and location of paralyzed vocal cords, history of hypertension, diabetes, cerebrovascular disease, and other underlying disease, smoking history, alcohol consumption and upper respiratory tract infection, and symptoms were investigated. Treatment was divided into three groups: the observation group, low-dose group, and high-dose group, and the recovery rate and time of vocal cord paralysis were analyzed in each group. Results Thirty-seven patients were enrolled in this study. There was no relationship between oral steroid use, dosage and recovery of vocal cord paralysis. Oral steroids showed a rapid recovery of vocal cord paralysis, but there was no statistically significant difference in the time of recovery of vocal palsy with or without steroids (p=0.673). In addition, there was no statistically significant difference in recovery rate between the period to start of treatment, presence of diabetes mellitus, and treatment modality, but the recovery rate was high in the group with upper respiratory tract infection history (p=0.041). Conclusion In IVFP, oral steroid therapy has no significant difference in time and extent of recovery compared to the case of spontaneous recovery.

Clinical Study of Acupuncture Theraphy of Gastrointestinal Side Effect of Levodopa: Focused on Idiopathic Pakinson's Disease Patients (레보도파제제의 위장관계 부작용에 대한 침치료 효과 연구-특발성 파킨슨병 환자를 대상으로-)

  • Yang, Dong-Ho;Lee, Kyung-Yun;Shin, Hyun-Seung;Jo, Song-Hyun;Lim, Chang-Sun;Lim, Jun-Hyuk;Yun, Suk-Hoon;Lee, Han;Kang, Myoung-Jin
    • Journal of Acupuncture Research
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    • v.27 no.6
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    • pp.11-21
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    • 2010
  • Objective : This study was aimed at investigating the therapeutic effects of acupuncture on gastrointestinal side effect of Levodopa on idiopathic Pakinson's disease patients. Methods : The subjects of this study were 42 patients with idiopathic Parkinson's disease. We divided them into two groups; acupuncture treatment group, no treatment group. We treated the former group with acupuncture therapy focusing on gastrointestinal side effect of Levodopa while administering Levodopa as well. And the latter group was also dosed up with Levodopa without acupuncture therapy. To see the effect of acupuncture treatment clearly, we used gastrointestinal syndrome rating scale (GSRS) and visual analog scale (VAS) and compared the GSRS grade and VAS score of two groups statistically, after 1, 2, 3, 4 weeks since they have been under the treatment. Results : This study suggests that the group who has been treated with acupuncture on gastrointestinal side effect of Levodopa on idiopathic pakinson's disease patients showed higher GSRS grade and VAS score than the one that has not. But, We could't find statistical significance between the two groups on improvement of GSRS grade and VAS score. Conclusions : These results proved that acupucture theraphy might be available for re lieving symptoms related with gastrointestinal side effect of Levodopa than the one that has not. But further studies are necessary.

Study of Ryodoraku Parameters for Diagnosing Idiopathic Facial Paralysis Patients (특발성 안면신경마비 환자의 진단도구로서의 양도락 지표 연구)

  • Yoo, Seung-Yeon;Kwon, Hyo-Jung;Kim, Young-Jin;Lee, Seung-Hoon;Chung, Jie-Youn;Kwak, Hyun-Young;Kim, Ji-Hye;Seon, Jong-In;Lim, Sung-Keun;Park, Young-Bae
    • Journal of Acupuncture Research
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    • v.27 no.6
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    • pp.95-100
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    • 2010
  • Objectives : The aim of this study was to investigate the characteristics of Ryodoraku and association of Ryodoraku in Idiopathic Facial Paralysis Patients Methods : Subjects were 53 patients with Facial palsy patients and 28 normal people. We calculated the average Ryodoraku score(RS, ${\mu}A$) and each variation from physiologic range of 12 Ryodoraku points, and investigated the incidence when left and right points were simultaneously below(bilateral deficiency) or above(bilateral excess) physiologic range. Results : The electric current value of several meridian of normal group was more higher in idiopathic facial palsy group than in normal group. The measurement value of Ryodoraku followed sex was not significant statistically. Conclusions : These findings suggest that the measurement value of several Meridians of Ryodoraku is more higher in idiopathic facial palsy group than in normal group, because Ryodoraku has low correlation with Parasympathetic nerve.

The Study on the Effect of Acupuncture on UPDRS and Heart Rate Variability in the Patients with Idiopathic Parkinson's Disease (태충(太衝) 양릉천(陽陵泉)의 침(針)자극이 특발성 파킨슨 환자의 UPDRS 및 HRV Parameter에 미치는 영향)

  • Jung, Ji-Chul;Kim, Kun-Hyung;Park, Yeon-Chul;Kim, Haeng-Bum;Lee, Sang-Hoon;Chang, Dae-Il;Lee, Yun-Ho
    • Journal of Acupuncture Research
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    • v.23 no.3
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    • pp.143-153
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    • 2006
  • Introduction : This study was designed to evaluate the effect of acupuncture on Unified Parkinson's Disease Rating Scale (UPDRS) and Heart Rate Variability (HRV) of patients with Parkinson's disease Methods: Subjects were voluntarily recruited through newspaper and internet advertisement. All the subjects were confirmed as idiopathic parkinson's disease by a neurologist. Acupuncture was applied 2 times a week for four weeks by oriental medical doctor at Kyung-hee University hospital. Acupuncture points used were GB34 and LR3. The patient's symptoms were assessed before and after 4 weeks of treatment by UPDRS and HRV. HRV was measured for 5 minutes before and after 4 weeks of treatment. Results : The results were as follows; 1. In both groups, UPDRS scores were significantly improved after 4 weeks compared to the pre-treatment 2. After 4 weeks of treatment UPDRS score differences between the two groups were insignificant 3. After 4 weeks of treatment HRV parameter scores showed statistically insignificant differences between the two groups. SDNN parameters of the Experimental group were significantly increased. Conclusion : This study suggests that acupuncture treatments can be applicable to improve symptoms in the patients with idiopathic Parkinson's disease. Further study on the acupuncture and HRV in the patients with Parkinson's disease is recommended.

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Comparison of Movement of Rapid Alternating Movements of Hands in Idiopathic Parkinson's Disease Patients and Normal Subjects using Angular Velocity Measurement System (각속도 측정시스템을 이용한 특발성 파킨슨병 환자와 정상인의 빠른 손놀림 동작의 비교)

  • Kim, Ji-Won;Kwon, Yu-Ri;Eom, Gwang-Moon;Jun, Jae-Hoon;Yi, Jeong-Han;Lee, Jeong-Whan;Kwon, Do-Young;Koh, Seong-Beom;Park, Byung-Kyu
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.59 no.3
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    • pp.674-677
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    • 2010
  • The purpose of this study was to analyze bradykinesia of forearm movement in patients with Parkinson's disease (PD) as compared to those of normal subjects. A gyrosensor was selected for the measurement of forearm movement, because it can provide angular velocity signal which is free from the gravitational artifact and also because it can be conveniently used during clinical test of bradykinesia. Forty PD patients (age: $65.7\pm11.1$ yrs, H&Y stage:$2.3\pm0.5$), 14 age-matched elderly subjects ($65\pm3.9$ yrs) and 17 healthy young subjects ($24\pm2.1$ yrs) participated in this study. Angular velocity during forearm movement of pronation/supination was measured in both arms. Suggested quantitative measures of bradykinesia were root-mean-squared (RMS) angular velocity, RMS angle, peak power and total power which were derived from the angular velocity. ANOVA showed that all measures were significantly different among three groups (p<0.001). Subsequent post-hoc test revealed that all measures in PD patients were significantly smaller than in healthy elderly and healthy young subjects (p<0.05). This results suggest that PD patients can be differentiated from normal subjects using suggested measures.

Effect of Moxibustion Treatment on UPDRS and Heart Rate Variability in Idiopathic Parkinson's Disease Patients (특발성 파킨슨병 환자에 대한 뜸치료가 UPDRS 및 심박변이도에 미치는 영향)

  • Park Sang-Min;Lee Sang-Hoon;Jung Ji-cheol;Kim Kun-Hyun;Park Hi-Joon;Lim Sabina;Chang Dae-Il;Lee Yun-ho
    • The Journal of Korean Medicine
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    • v.26 no.2 s.62
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    • pp.176-181
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    • 2005
  • Objectives: This study was designed to evaluate the effect of moxibustion on UPDRS and heart rate variability of patients with Parkinson's disease. Methods: Subjects were voluntarily recruited through newspapers and internet. All subjects were confirmed as showing idiopathic Parkinson's disease by a neurologist. Moxibustion therapy was performed 5 times a week by the patient's family at home and once a week by an oriental medical doctor in hospital. Moxibustion points were GV20, CV12, ST36, BL18, and BL20. Intensity was up to pain threshold to prevent patients getting burned. The patient's symptoms were assessed before and after 8 weeks of treatment by unified Parkinson's disease rating scale (UPDRS). Heart rate variability was measured for 5 minutes before and after the treatments. Results: Total UPDRS scores were significantly improved after 8 weeks compared to pre-treatment (p<0.05). There were significant decrease of mean heart rates (p<0.05) and increase of SDNN and TP (p<0.05) after 8 weeks' moxibustion treatments. There were no significant changes in other components of heart rate variability. Conclusions: This study suggests that moxibustion treatments can be applicable to improve not only symptoms but also heart rate variability in the patients with idiopathic Parkinson's disease.

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The Effects of Short Term Schroth Exercise on the Cobb Angle, Angle of Trunk Rotation, Cosmetic Appearance, and Quality of Life in Idiopathic Scoliosis (단기간 슈로스(Schroth) 운동이 특발성 척추측만증 환자의 척추측만각도(Cobb Angle), 몸통회전도, 외형 그리고 삶의 질에 미치는 영향)

  • Kim, Ji-Seon;Lee, Sook;Lim, Dong-Hwan;Cho, Eun-Woo;Seo, Dong-Kwon
    • Journal of the Korean Society of Physical Medicine
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    • v.12 no.1
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    • pp.93-101
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    • 2017
  • PURPOSE: The purpose of this study was to describe the effects of short term Schroth exercise on the Cobb angle, angle of trunk rotation (ATR), cosmetic appearance, and quality of life (QOL) in idiopathic scoliosis patients. METHODS: Five subjects with idiopathic scoliosis, (female, 3; male, 2) curvature type: thoracic, 2; lumbar, 3 underwent short term Schroth exercise for seven days. The exercise was performed for 3 h long sessions per day. The Cobb angle and QOL were measured before and after the intervention. ATR and cosmetic appearance were measured once. Sessions consisted of one baseline, seven intervention and three follow-up phases. The sessions were conducted with a one day interval. RESULTS: After the intervention, the Cobb angle was found to be significantly improve (p <.05), while the QOL did not differ (p>.05). The ATR showed decreased trends in the intervention phase. Data points during the intervention and follow-up phases showed a decrease in comparison with data points at the baseline, indicating that Schroth exercise might be effective in reducing the ATR and that these effects can be maintained after the intervention. Cosmetic appearance did not showed changed trends during the Schroth exercise intervention phase. CONCLUSION: Our results suggest that short term Schroth exercise may be valuable in improving the Cobb angle and ATR in patients with idiopathic scoliosis.