• Journal of the Korea Academia-Industrial cooperation Society
• /
• 제14권2호
• /
• pp.804-810
• /
• 2013

The purpose of this study was to apply treadmill training through motor learning to cerebral palsy children and examine its effects on their motor Functions and balance. The subjects of this study were 16 spastic diplegia children who had difficulty in independent gait, and GMFCS level III, IV. The participant's were allocated randomy to 2 groups: a motor learning group(n=8) and the control group(n=8), Both groups received muscle strengthening exercise for 3 session, 30 minutes per week over 7 weeks period. Data collected from the 16 spastic diplegia children the results were as follows. The motor learning group showed significant increase in motor function(p<.05). The motor learning group showed significant increase in balance(p<.05). Between motor learning group and control group, motor functions and balance was a statistically significant difference(p<.05).

• Journal of Korean Society of Forest Science
• /
• 제103권3호
• /
• pp.503-509
• /
• 2014

The purpose of this study was to investigate the effect of Forest-walking exercise on gait pattern in the elderly. The subjects (n=37) were assigned to 2 groups: Forest-walking exercise (FWE) group (n=19, $66.34{\pm}4.31$ years old) and In-door treadmill-walking exercise (ITWE) group (n=18, $67.18{\pm}2.78$ years old). The subjects participated in FWE program or ITWE program (3 times/week, 80 min/day) for 12 weeks. The subjects were tested on functional fitness (strength, endurance, agility/balance, BMI) and gait pattern (cadence, velocity, and stability) at the beginning and the end of the 12-weeks program. For data analysis, mean and standard deviation scores were calculated, and independent t-test and repeated two-way ANOVA were used. The results of this study were as follow: First, FWE group was significantly more improved than ITWE group on functional fitness(lower-body muscular strength, lower-body flexibility, mobility, cardiorespiratory endurance) after 12-weeks exercise program. But both groups showed equally improvements on functional fitness (upper-body muscular strength, upper-body flexibility, BMI). Second, FWE group was significantly more improved than ITWE group on cadence, gait velocity, and gait stability after 12-weeks exercise program. Therefore, this study may suggest that Forest-walking exercise based on sensory-motor functional integration improves efficiently functional fitness and gait pattern in the elderly, and further becomes an effective exercise method that makes more dynamic life, and prevents from falling.

• Journal of Life Science
• /
• 제21권9호
• /
• pp.1259-1265
• /
• 2011

The purpose of this study was to determine whether a single bout of aerobic exercise affects the expression level of toll-like receptor4 (TLR4), IL-6, TNF-${\alpha}$, and suppressor of cytokine signaling-3 (SOCS-3) expression in rat hindlimb muscles depending on fiber types. To accomplish this, thirteen 7-wk Balb/c male mice were randomly assigned to an experimental group or a control group. The exercise protocol consisted of a single bout of treadmill exercise (inclination $10^{\circ}$, speed 17 cm/sec 10 min, 33 cm/sec 10 min, 50 cm/sec) and the animals were killed 24 hr after the exhaustion protocol. The level of TLR4, IL-6, TNF-${\alpha}$, and SOCS-3 mRNA expression was measured by quantitative real-time PCR in soleus and plantaris muscles. A single bout of aerobic treadmill exercise increased TLR4 mRNA expression in the soleus muscle (p<0.05), whereas plantaris TLR4 mRNA expression did not change. Additionally, acute exercise led to a significant increase in IL-6, TNF-${\alpha}$, and SOCS-33 mRNA in the soleus muscle, while transcripts of these genes were not affected by exercise in the plantaris muscle. In conclusion, expression level of several immune-related genes such as TLR4, cytokines, and SOCS-3 is regulated by acute exercise in a fiber type specific manner.

• 한국체육학회지인문사회과학편
• /
• 제58권4호
• /
• pp.481-492
• /
• 2019

The purpose of this study was to investigate the effects of treadmill exercise on cerebellar astrocyte activation and purkinje cells, neurotrophic factors expression, and motor function in aged rats. Sprague-Dawley (SD) rats were used and divided into three groups; (1) Young Control Group (YCG; 3months aged, n=10); (2) Old Control Group; (OCG; 24months aged, n=10); (3) Old Exercise Group (OEG; 24months aged, n=10). Rats were then subjected to treadmill exercise for 5 days per week for 12 weeks during which time the speed of the treadmill was gradually increased. The results revealed that in the rota-rod test, motor function was significantly increased in the OEG compared to the OCG (p<.05), and similarly YCG. Number of calbindin-positive purkinje cell expression significantly increased in the cerebellar vermis of OEG compared to the OCG (p<.05), and similarly YCG. GFAP-, NMDAR-positive cell expression significantly increased in the OEG (respectively p<.001), GFAP and GLAST protein levels were significantly increased in the cerebellum of OEG compared to the OCG (p<.05, p<.001) and similarly YCG. BDNF and NGF protein levels were highest in the YCG, increased in the OEG compared to OCG (p<.001, p<.05). These result show that regular exercise not only improved astrocyte activation, but also increased purkinje cell expression in the cerebellum and motor function by increasing the neurotrophic factors in aged rats.

• 기계와재료
• /
• 제23권1호
• /
• pp.60-69
• /
• 2011

지면 변화 트레드밀 기기는 경사도 변화가 가능하며 안전사고를 예방하는 안전장치, 노인의 보행속도에 적합한 속도를 구현할 수 있는 자동 속도 구현장치, 기존 트레드밀에서 구현하지 못하는 다양한 지면 조건을 현실화할 수 있는 재질의 바닥 및 가상현실 컨텐츠와 연동하여 속도 조절이 가능한 지능형 조절장치로 구성된다. 때문에 가상의 외부 환경이 3D로 구현된 컨텐츠와 연동하여 노인들이 걷기 운동을 즐길 수 있도록 구현 가능한 것이 특징이다. 본 고에서는 노인 및 장애인들에게 적합한 속도 구현과 안전사고 예방 및 다양한 지면 조건을 구현한다는 장점이 있는 지면 변화 트레드밀 기기에 대해 소개하였다.

• Proceedings of the KIPE Conference
• /
• 전력전자학회 2018년도 전력전자학술대회
• /
• pp.412-413
• /
• 2018

고성능 트레드밀 시스템은 운동부하에 따른 큰 맥동부하 특성을 가지며 저속에서도 안정적인 제어 성능이 요구된다. 본 논문에서는 기존에 연구된 유도전동기 센서리스 제어 알고리즘을 검토하여 저속에서 부하의 변화에 강인한 특성을 갖는 알고리즘에 대하여 논하고 이를 트레드밀 시스템에 적용한 결과에 대하여 기술한다. 슬립제어기반의 속도제어기를 구성하였으며 벡터제어기반의 슬립연산 알고리즘을 도입하여 90rpm의 저속에서도 부하변동에 강인하고 안정적인 속도제어가 가능한 트레드밀 제어시스템을 구축하였다. 연구결과는 PSIM 시뮬레이션을 통하여 검증하였다.

• Journal of Life Science
• /
• 제14권5호
• /
• pp.741-746
• /
• 2004

This study investigated the response of GLUT-4 and GRP-78 protein expression in soleus muscle of Streptozotocin-induced diabetic rats with caffeine oral administration by imposing different exercise intensities. Rats were randomly divided into 5 groups (n=6 in each group): diabetic group (D), diabetic-caffeine group (DC), diabetic-caffeine group with low intensity exercise (DCL), diabetic-caffeine group with moderate intensity exercise (DCM) and diabetic-caffeine group with high intensity exercise (DCH). The rats in DCL, DCM and DCH groups were exercised acutely by treadmill running for 8 meter/m, 16 meter/m and 25 meter/m, respectively. Little difference in GLUT-4 protein expression was shown in DC and DCL compared to D. GLUT-4 protein expression was decreased in DCM and increased in DCH was observed. GRP-78 protein expressions in DCL, DCM and DCH were little lower than that of D. An increase in GRP-78 protein was observed in DC. Improved insulin sensitivity with acute high intensity exercise gives the rats important therapy that lowers insulin requirement. This improvement of insulin sensitivity for glucose transport in skeletal muscle results from translocation of the GLUT-4 protein from the endoplasmic reticilum to the cell surface and increase in total quantity of GLUT-4 protein. It is not clear what mechanism reduced GRP-78 protein level in exercise group. It is merely conjectured that caffeine-induced lipolysis provided cells with energy in abundance and this relieved stress which cells are subjected to receive when performing exercise.

• Journal of Life Science
• /
• 제20권3호
• /
• pp.444-452
• /
• 2010

The purpose of this study was to investigate the effects of treadmill exercise on $A{\beta}$-42, cytochrome c, SOD-1, 2 and Sirt-3 protein expressions in brain cytosol and mitochondria in mutant (N141I) presenilin-2 transgenic mice with Alzheimer's disease (AD). The mice were divided into four groups (Non-Tg-sedentary, n=5; Non-Tg treadmill exercise, n=5; Tg-sedentary, n=5; Tg treadmill exercise, n=5). To evaluate the neuroprotective effect of treadmill exercise, Non-Tg and Tg mice were subjected to exercise training on a treadmill for 12 wk, after which their brain cytosol and mitochondria were evaluated to determine whether any changes in the cognitive performance, $A{\beta}$-42 protein, cytochrome c protein, anti-oxidant enzymes (SOD-1, SOD-2) and Sirt-3 protein had occurred. The results indicated that treadmill exercise resulted in amelioration in cognitive deficits of Tg mice. In addition, the expressions of mitochondrial $A{\beta}$-42 and cytosolic cytochrome c protein were decreased in the brains of Tg mice after treadmill exercise, whereas antioxidant enzymes, SOD-l and SOD-2 were significantly increased in response to treadmill exercise. Furthermore, treadmill exercise significantly increased the expression of Sirt-3 protein in Non-Tg and Tg mice. Taken together, these results suggest that treadmill exercise is a simple behavioral intervention which can sufficiently improve cognitive performance and inhibit $A{\beta}$-induced oxidative stress in AD.

• The Journal of the Korea Contents Association
• /
• 제9권12호
• /
• pp.656-664
• /
• 2009

The purposes of this study were to examine whether aquatic exercise has influence on the neuroplasticity and vestibulo-motor function in diffuse brain injury rats. 80 Sprague-Dawley rats were assigned to four groups; Group I: control group (n=20), Group II: aquatic exercise (n=20), Group III: treadmill exercise with change of velocity and inclination (n=20), Group IV: simple treadmill exercise (n=20). And we applied exercise each groups for 3 weeks except Group I. Before the rats were sacrificed to identify immunohistochemistry study at each time of measurement day, Rota-Rod test was given to assess changes in vestibulomotor function. then, the immunohistochemistry study of GAP-43 in discrete regions of the rat brain was performed to measure changes in neuroplasticity. The results demonstrate that aquatic exercise group is more effective than other groups. expression of GAP-43 and vestibulo-motor function were increased most in aquatic exercise group. Therefore, this study suggest that aquatic exercise may effective therapeutic approach to increase neuroplasticity and vestibulo-motor function in traumatic brain injury.

• Journal of Life Science
• /
• 제17권11호
• /
• pp.1464-1471
• /
• 2007

Diabetes mellitus is a chronic metabolic disorder, leading to many complications including cognitive deficit. Regular exercise has often been recommended as a therapeutic maneuver to the diabetic patients for the prevention of secondary complications. In the present study, the effects of treadmill exercise on memory and brain-derived neurotrophic factor (BDNF) in the hippocampus of streptozotocin (STZ)-induced diabetic rats were investigated. Male SD rats, aged 6 weeks, were randomly assigned to the following three groups: control group(n=8), STZ-induced diabetic group(n=8), and STZ-induced diabetes and exercise group(n=8). Diabetes was induced by a single injection of STZ (50 mg/kg body weight). Treadmill running was conducted with duration and frequency of 30 minutes and 5 times per week, respectively, for 8 weeks. Memories were tested in the Morris water maze. Western blotting was performed to detect BDNF expression in the hippocampus. In this study, we found that compared to the control group, the STZ-induced diabetes group had a significantly impaired cognitive performance along with suppressed BDNF expression in the hippocampus and the exercise group had a higher cognitive function in diabetic rats. Therefore, the current findings of the study show that a treadmill running exercise can improve diabetes-induced impairment of cognitive function. And the improved cognitive function appears to be related to an alleviation in diabetes-induced BDNF expression in hippocampus.