• Microbiology and Biotechnology Letters
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• v.44 no.3
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• pp.383-390
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• 2016

Mesenchymal stem cells (MSCs) are multipotent stem cells that can be differentiated into a variety of cell types, including adipocytes, osteoblasts, chondrocytes, β-pancreatic islet cells, and neuronal cells. MSCs have been reported to exhibit immunomodulatory effects in many diseases. Many studies have reported that MSCs have distinct roles in modulating inflammatory and immune responses by releasing bioactive molecules. Exosomes are cell-derived vesicles present in biological fluids, including the blood, urine, and cultured medium of cell cultures. In this study, we investigated the immunomodulatory effects of mouse adipose tissue-derived MSCs (mAD-MSCs), cultured medium (MSC-CM) of mAD-MSCs, and mAD-MSC-derived exosomes (MSC-Exo) on lipopolysaccharide (LPS)-induced RAW 264.7 cells. We observed that the expression levels of IL-1β, TNF-α, and IL-10 were significantly increased in LPS-stimulated RAW 264.7 cells compared to those in LPS-unstimulated RAW 264.7 cells. Additionally, these values were significantly (p < 0.05) decreased in mAD-MSCs-RAW 264.7 cell co-culture groups, MSC-CM-treated groups, and MSC-Exo-treated groups. MSCs can modulate the immune system in part by secreting cytokines and growth factors. We observed that immunomodulatory factors such as IL-1β, TNF-α, and IL-10 were secreted by mAD-MSCs under co-culturing conditions of mAD-MSCs with activated RAW 264.7 cells. In addition, mAD-MSC-derived exosomes exhibited similar immunomodulatory effects in activated RAW 264.7 cells. Therefore, our results suggest that mAD-MSCs have an immunomodulatory function through indirect contact.

• Journal of Broadcast Engineering
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• v.10 no.4 s.29
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• pp.548-556
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• 2005

In wireless network environments, wireless channels are characterized by time-varying fading and interference conditions, which may lead to burst packet corruptions and delay variation. This can cause severe quality degradation of streaming media. To guarantee successful transmission of media over the hostile wireless networks, where channel conditions are highly fluctuating, a flexible and network-adaptive transport method is required. Thus, we propose a network-adaptive transport error control consisting of packet-level interleaved FEC and delay-constrained ARQ, which acts as an application-level transport method of streaming media to alleviate burst packet losses while adapting to the changing channel condition in wireless networks. The performances of the proposed network-adaptive transport error control, general error control schemes, and hybrid schemes are evaluated by a developed simulator at the transport-level and video quality of streaming media. Simulation results show that the proposed mechanism provides the best overall performance among compared other schemes in terms of the transport-level performance of error control and the performance of video quality for streaming media.

• Journal of Internet Computing and Services
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• v.13 no.3
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• pp.115-126
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• 2012

Mashups have become very popular over the last few years, and their use also varies for IT convergency services. In spite of their popularity, there are several challenging issues when combining Open APIs into mashups, First, since portal sites may have a large number of APIs available for mashups, manually searching and finding compatible APIs can be a tedious and time-consuming task. Second, none of the existing portal sites provides a way to leverage semantic techniques that have been developed to assist users in locating and integrating APIs like those seen in traditional SOAP-based web services. Third, although suitable APIs have been discovered, the integration of these APIs is required for in-depth programming knowledge. To solve these issues, we first show that existing techniques and algorithms used for finding and matching SOAP-based web services can be reused, with only minor changes. Next, we show how the characteristics of APIs can be syntactically defined and semantically described, and how to use the syntactic and semantic descriptions to aid the easy discovery and composition of Open APIs. Finally, we propose a goal-directed interactive approach for the dynamic composition of APIs, where the final mashup is gradually generated by a forward chaining of APIs. At each step, a new API is added to the composition.

• The Journal of the Korea Contents Association
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• v.16 no.10
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• pp.598-607
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• 2016

The purpose of this study is to suggest necessity of idea expression method suitable for people in our country and deduct Graphic Ideation method by grasping problems of existing idea expression method. The idea expression method (association stimulating method, conceptual shifting method, information combination method) used by many graphic designers is effective in suggesting initial keyword, but has difficulty in the course of deducting the concept. Though deduction of core keyword is important to develop as a concept, the course of separation, combination in keyword connection play an important role, and most of idea expression methods are unavailable for suggesting concrete method for the course. Also as most of idea expression methods were developed and delivered in English-speaking world, it is suitable in English-speaking world culture which has thinking focused on words, but people in our country, which have thinking focusing on narration, cannot consider difference in language thinking due to limitation in idea for each stage. This study deducted idea expression method suitable for emotion of people in our country by proving the value of this idea expression method with style of suggesting and demonstrating 4 hypotheses in order to make the course for easy connection, separation, combination of keyword deducted by existing idea expression method, as well as suggesting idea expression method design based on these hypotheses. This idea expression method used rhetoric so that it is suitable for people our country who are strong for narration expression.

• Journal of Korea Multimedia Society
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• v.1 no.2
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• pp.239-248
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• 1998

Software reengineering is making various research for solutions against problem of maintain existing system. Reengineering has a meaning of development of softwares on existing systems through the reverse-engineering and the forward-engineering. It extracts classes from existing system's softwares to increase the comprehension of the system and enhance the maintenability of softwares. Most of the important concepts used in reengineering is composition that is restructuring of the existing objects from other components. The classes and clusters in storage have structural relationship with system's main components to reuse in the higher level. These are referenced as dynamic informations through structuring an architect for each of them. The classes are created by extractor, searcher and composer through representing existing object-oriented source code. Each of classes and clusters extract refined informations through optimization. New architecture is created from the cluster based on its classes' relationship in storage. This information can be used as an executable code later on. In this paper, we propose the tools, it presented by this thesis presents a new information to users through analysing, based on reengineering, Object-Oriented informations and practicing composition methodology. These composite classes will increase reusability and produce higher comprehension information to consist maintainability for existing codes.

• Journal of the Korean Association of Geographic Information Studies
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• v.10 no.1
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• pp.10-21
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• 2007

The Doam-dam watershed, located at Kangwon Province, Korea, has been experiencing significant changes in land uses, conversion from forest to agricultural/urban areas, with human involvements. However, no thorough investigation of the landscape impacts of land use changes was performed at this watershed using the scientific analytical tool. Thus, the FRAGSTATS model was utilized to quantitatively analyze the landscape impacts of forest fragmentation in this study. To provide the detailed explanations for 11 landscape indices considered in this study, two artificial and simplified landscapes, before and after fragmentations, were constructed. Using these 11 indices, the landscape impacts of forest fragmentation in 19 subwatersheds of the Doam-dam watershed were analyzed. The S1 subwatershed, one of 19 subwatersheds of the Doam-dam watershed, was found to have experienced the significant forest fragmentation from 1985 to 2000 based on landscape analysis using the FRAGSTATS model. The results obtained in this study can be used to evaluate the water quality impacts of forest fragmentations/land use changes at watershed scale level, and establish environment-friendly land use planning based on the results obtained using landscape analytical tool, FRAGSTATS.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.27 no.4
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• pp.212-219
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• 2017

To become a person that is suitable to the 'High-Touch' generation where emotion takes over, we can focus on 6 skill including design, story, harmony, empathy, play, and meaning. Among these skills, harmony with design was chosen as the most important skill. Design can be seen as the basic element of all business, but it will be difficult to match the flow of the future Sensibility and intuitive generation with just the modern design that has been made based on reasonable and objective information and knowledge. This study suggests system and standardization of Sensibility surface processing design that satisfies great quality, attractive quality and Sensibility quality by applying surface processing design of product and Sensibility cognitive factors felt by the consumer by setting differentiated strategy and CMF (Color, Material, Finishing) understanding along with the importance of design materials in primary aspect. By considering the efficacy/characteristic of new surface processing characteristic/differentiation/possibility of implementation according to setting direction of differentiated CMF strategy per type of parts applied to the product, visual surface processing sample was implemented. Through this, it is expected that practical communication connected tool and Sensibility surface processing design's strategic access framework can be applied by understanding and sharing comprehensive elements such as target product, part type, applied material, applied surface processing, surface color, surface texture, and implementing feeling to environments such as designers, CMF designers, surface processing experts, and engineers in IT, electronics, and other areas. when developing a product.

• Journal of the Korean Institute of Telematics and Electronics T
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• v.36T no.4
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• pp.71-81
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• 1999

We propose a new CPLD(Complexity Programmable Logic Device) technology mapping algorithm improving run-time under time constraint. In our technology mapping algorithm, a given logic equation is constructed as the DAG(Directed Acyclic Graph) type, then the DAG is reconstructed by replicating the node that outdegree is more than or equal to 2. As a result, it makes delay time and the number of CLBs, run-time to be minimized. Also, after the number of multi-level is defined and cost of each nodes is calculated, the graph is partitioned in order to fit to k that is the number of OR term within CLB. The partitioned nodes are merged through collapsing and bin packing is performed in order to fit to the number of OR term within CLB(Configurable Logic Block). In the results of experiments to MCNC circuits for logic synthesis benchmark, we can shows that proposed technology mapping algorithm reduces run-time and the number of CLBs much more than the TEMPLA.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.19 no.2
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• pp.121-129
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• 2008

In this paper, we present a fast analysis of multilayer microstrip fractal structure by using the fast multipole method (FMM). In the analysis, accurate spatial green's functions from the real-axis integration method(RAIM) are employed to solve the mixed potential integral equation(MPIE) with FMM algorithm. MoM's iteration and memory requirement is $O(N^2)$ in case of calculation using the green function. the problem is the unknown number N can be extremely large for calculation of large scale objects and high accuracy. To improve these problem is fast algorithm FMM. FMM use the addition theorem of green function. So, it reduce the complexity of a matrix-vector multiplication and reduce the cost of calculation to the order of $O(N^{1.5})$, The efficiency is proved from comparing calculation results of the moment method and Fast algorithm.

• The Journal of the Korea Contents Association
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• v.10 no.11
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• pp.20-29
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• 2010

The typical Kinetic Family Drawing (KFD) Web database system, a form of prototype system, has been developed, relying on the suggestions from family art therapists, with an aim to handle large amounts of assessment data and to facilitate effective implement of assessment activities. However, unfortunately such a system has an intrinsic problem that it fails to collect clients' behaviors, attitudes, facial expressions, voices, and other critical information observed while they are drawing. Accordingly we propose the ontology based video event analysis and video retrieval system in this paper, in order to enhance the function of a KFD Web database system by using a web camera and drawing tool. More specifically, a newly proposed system is designed to deliver two kinds of services: the client video retrieval service and the sketch video retrieval service, accompanied by a summary report of occurred events and dynamic behaviors relative to each family member object, respectively. The proposed system can support the reinforced KFD assessments by providing quantitative and subjective information on clients' working attitudes and behaviors, and KFD preparation processes.