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The Triple Helix System of Innovation in the Oresund Food Cluster (외레순 식품 클러스터의 트리플 힐릭스 혁신체계)

  • Lee, Jong-Ho;Kim, Tae-Yeon;Lee, Chul-Woo
    • Journal of the Economic Geographical Society of Korea
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    • v.12 no.4
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    • pp.388-405
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    • 2009
  • This paper examines the triple helix innovation system in the Oresund food cluster, considered as one of the most competitive food clusters in the globe. The result of the case study represents that the triple helix system of the Oresund food cluster is composed of three layers of triple helix spaces. Such three triple helix spaces play a crucial role in making the industry-university-government relationships interactive and dynamic. First, knowledge spaces in the Oresund food cluster are very strong and competitive in education and R&D capabilities in related to the food sector. 14 universities in the Oresund region are connected and coordinated by the integrated organization body, called the Oresund University. Second, the Oresund Food Network(OFN), as a central consensus space in the Oresund food cluster, functions as a pivotal organization that facilitates and coordinates cooperations between firms and universities. Third, most important innovation space in the triple helix system of Oresund food cluster can be science parks and business incubators such as Ideon Science Park, which contribute to linking, between research and commercialization, and between firms and universities in the region. In a nutshell, the Oresund food cluster has been evolved as an innovative regional cluster on the basis of well-established three-layered triple helix spaces of regional innovation system.

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Comparative Study on the Clinical Characteristics and Effects of Korean Medical Treatment between the Upper and Lower Lumbar Single Level Disc Herniation (상부요추와 하부요추 단분절 추간판 탈출증 환자의 임상적 특성과 한방치료 효과 비교연구)

  • Lee, Ju-Young;Kim, Yong-Hyeon;Kim, Kwang-Hwi;Kim, Tae-Yeon;Lee, Tae-Geol;Lee, Sang-Woon;Chu, Hui-Yeong;Jung, Hui-Kyeong;Jung, Bum-Hwan
    • Journal of Korean Medicine Rehabilitation
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    • v.28 no.4
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    • pp.43-50
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    • 2018
  • Objectives Upper lumbar disc herniation (LDH) (L1/2, L2/3) has specific anatomical characteristics and different outcome after conventional treatment compared to lower LDH (L3/4, L4/5, L5/S1). The purpose of this study was to compare the clinical features and effects of korean medical treatment of upper LDH between lower LDH. Methods We retrospectively reviewed the clinical data collected from 121 patients who was had admitted at the Haeundae Jaseng Hospital of Korean Medicine from June 1st, 2014 to August 31th, 2018. The patients who had treated at L1/2, L2/3 level LDH were grouped and compared with those treated at the L3/4, L4/5, L5/S1 level. We reviewed the patient characteristics such as age, the positive rate of Straight Leg Raise Test (SLR test), the presence or absence of previous lumbar surgery. Numeric Rating Scale (NRS) and Oswestry Disability Index (ODI) were evaluated at adimission and discharge. Results Mean age was significantly higher at upper LDH group and positive rate of SLR test was higher at lower LDH group. There was no significant difference of gender and previous lumbar surgery between two groups. Each group had a significant improvement of NRS, ODI scores. But between two groups, there was no significant difference of NRS, ODI scores. Conclusions Upper LDH group was older than lower LDH group. SLR test was useful tool to exclude upper LDH. Korean medical treatment was significantly effective to both upper and lower LDH groups. Further well designed prospective comparative studies are needed.

Comparative Analysis on Disc Resorption Rate of Lumbar Disc Herniation Patients after Korean Medicine Treatment and Predictive Factors Associated with Disc Resorption (요추 추간판 탈출증 환자의 한의치료 후 디스크 흡수율 비교 및 흡수에 영향을 주는 요인 분석 연구)

  • Kim, Yong-Hyeon;Lee, Ju-Young;Kim, Kwang-Hwi;Kim, Tae-Yeon;Lee, Tae-Geol;Lee, Sang-Woon;Chu, Hui-Yeong;Jeong, Hui-Gyeong
    • Journal of Korean Medicine Rehabilitation
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    • v.28 no.4
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    • pp.33-41
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    • 2018
  • Objectives The purpose of this study is to analyze the effects of Korean Medicine treatment on lumbar disc herniation (LDH) and predictive factors associated with disc resorption by magnetic resonance imaging (MRI). Methods A retrospective study was carried out in 79 lumbar disc herniation patients who had visited Haeundae Jaseng Hospital of Korean Medicine. Patients' diagnosis was based on MRI. MRI was performed on two or more occasions and patients were received Korean Medicine treatment within the period. The volume of each herniated disc was measured three-dimensionally and patient characteristics, interval between MRIs, herniated disc level, disc herniation type, disc migration, intactness of posterior longitudinal ligament (PLL), initial volume of herniated disc, modic change, disc resorption rate were statistically analyzed. Results The mean volumes of herniated discs before Korean Medicine treatment and after Korean Medicine treatment were $1,547.81{\pm}598.15mm^3$ and $947.06{\pm}335.28mm^3$, respectively. The mean resorption rate was $35.7{\pm}16.3%$. Disc extent, intactness of PLL and initial volume of herniated discs were significantly correlated with resorption rate (p=0.003, p=0.001 and p=0.024, respectively). Conclusions Korean Medicine treatment is an effective conservative treatment for lumbar disc herniation. Factors such as disc migration, intactness of PLL, initial volume of herniated disc have a significant association with disc resorption rate.

Analysis for Water Vapour Adsorption and Desorption Performance of Waste Paper-Mulberry according to Particle Size Control (폐닥나무의 입도제어에 따른 흡·방습 특성 분석)

  • Jo, Ki-Sic;Kim, Tae-Yeon;Seo, Sung-Kwan;Lee, Oh-Kyu;Chu, Yong-Sik
    • Resources Recycling
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    • v.29 no.2
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    • pp.8-17
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    • 2020
  • In this study, adsorption and desorption characteristics of pulverized waste paper-mulberry pellet and bast fiber were measured to confirm the applicability to humidity control products. Paper-mulberry powder was classified by 710-355㎛, 355-100㎛, 100-45㎛ and less than 45㎛ and used in experiment. Specific surface area increased from 1.02㎡/g to 1.35㎡/g as the particle size decreased from 710㎛ to under 45㎛. Adsorption and desorption performance decreased in the order of 355-100㎛, 710-355㎛, 100-45㎛, less than 45㎛ and bast fiber, adsorption content on each particle sizes were 141.1g/㎡, 147.1g/㎡, 135.7g/㎡, 129.0g/㎡ and desorption content were 117.2g/㎡, 123.6g/㎡, 110.2g/㎡, 93.3g/㎡. As a result, adsorption and desorption performance of paper-mulberry powder were superior to those of the bast fiber and these phenomenon can be considered that it caused by pore distribution in pellet and damage of fiber.

A Study on Risk Analysis and Acident Prevention Heater Interlock By-pass (Heater interlock by-pass로 인한 위험분석 및 사고방지에 대한 연구)

  • Son Jae-geun;Park Kyo-Shik;Kang Tae-Yeon;Yeo Yeong-Koo
    • Journal of the Korean Institute of Gas
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    • v.7 no.1 s.18
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    • pp.24-27
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    • 2003
  • In this paper it was investigated 15 heaters of CDU plant heater, NCC plant heater, CO plant heater, Aromatic plant heater and so on while running in our country. It was also analysed the standard of operation procedure, the action in alarm, the interlock system, the operating situation of the interlock by-pass and major accident about the heater and so on. This paper presents the installation of the on-line monitoring, the additional installation of the local pressure gauge and temperature gauge, the check in starting operation,'the management of the interlock by-pass, the change of manufacturer causing the disorder of instrument sensor, the management method of DCS alarm for methods of the interlock prevention and facilities improvement. It was few information about the heater interlock in the inside and outside of the country We mainly have studied with reflecting the opinion of the operator and manager on site, the sheet of process trouble and operation procedure and so on. we think that the accident relating to the interlock will significantly reduce if the companies apply the conclusion of this study(i.e. methods of the interlock prevention and facilities improvement).

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A Study on the Analysis of Energy Voucher Effects Using Micro-household Data (가구부문 미시자료를 활용한 에너지바우처 효과 추정에 관한 연구)

  • Lee, Eun Sol;Park, Kwang Soo;Lee, Yoon;Yoon, Tae Yeon
    • Environmental and Resource Economics Review
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    • v.28 no.4
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    • pp.527-556
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    • 2019
  • In Korea, nearly 100 billion won is spent annually under the name of energy voucher on 600,000 households for the last five years, and this is a unique case and hard to monitor worldwide. Therefore, no studies have been conducted to assess impacts of the energy voucher on energy consumption and cost burden alleviation for beneficiaries. This paper aims to demonstrate the effectiveness of energy vouchers in terms of energy expense. The propensity score matching was conducted on samples of low-income households based on the Korea Welfare Panel. Then, simple Difference-In-Differences and Fixed-Effect Difference-In-Differences models were applied to estimate the effect of energy vouchers. In results, the beneficiaries of energy vouchers would spend an additional 4,371~4,870 won per month on energy consumption. The ratio is equivalent to 51.9~57.7 percent of the aid, which is also the highest when compared with 23~56 percent of U.S. Food Stamp. In terms of energy welfare, voucher payment could become one of the best management practices. However, identifying the blind spots as non-reciprocal households and expanding the differential support mechanism that reflects the energy consumption environment should be solved in the future.

Exploring the Triple Helix Innovation System in the Dutch Food Cluster(Food Valley) (네덜란드 라흐닝언 식품산업 클리스터(푸드밸리)의 트리플 힐릭스 혁신체계)

  • Lee, Chul-Woo;Kim, Tae-Yeon;Lee, Jong-Ho
    • Journal of the Korean association of regional geographers
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    • v.15 no.5
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    • pp.554-571
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    • 2009
  • This paper explores the triple helix innovation system in Food Valley in the Netherlands which is considered one of the most innovative food clusters in the world. The triple helix approach has been so far little tackled in the literature on innovation system and cluster. However, tills approach can be a useful tool for understanding the dynamic characters and knowledge transfer mechanism of industrial cluster. On the basis of an in-depth case study, we argue that Food Valley has evolved through four circles of growth in the triple helix innovation system. From the mid-2000s onward, it is seen that Food Valley has been on the stabilized circle in the triple helix system of innovation. Centered upon Wageningen UR, local universities and research centers play a pivotal role in building the triple helix innovation system. To cope with radical changes in markets and technology since the late 1980s, local firms have made a great deal of effort to reinforce the university-industry partnership. On the other hand, government agencies have played a critical role for establishing institutional milieu that facilitate university-industry partnerships and local knowledge transfer and spillover.

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Silybin Synergizes with Wnt3a in Activation of the Wnt/${\beta}$-catenin Signaling Pathway through Stabilization of Intracellular ${\beta}$-Catenin Protein (Silybin에 의한 Wnt/${\beta}$-catenin 신호전달체계의 활성화)

  • Kim, Tae-Yeoun;Oh, Sang-Taek
    • Microbiology and Biotechnology Letters
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    • v.40 no.1
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    • pp.50-56
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    • 2012
  • The Wnt/${\beta}$-catenin signaling pathway regulates diverse developmental processes and adult tissue homeostasis. Inappropriate regulation of this pathway has been associated with human diseases, such as cancers, osteoporosis, and Alzheimer's disease. Using a cell-based chemical screening with natural compounds, we discovered silybin, a plant flavonoid isolated from the Silybum marianum, which activated the Wnt/${\beta}$-catenin signaling pathway in a synergy with Wnt3a-conditioned medium (Wnt3a-CM). In the presence of Wnt3a-CM, silybin up-regulated ${\beta}$-catenin response transcription (CRT) in HEK293-FL reporter cells and 3T3-L1 preadipocytes through stabilization of intracellular ${\beta}$-catenin protein. Silybin and Wnt3a-CM synergistically reduced expression of important adipocyte marker genes including peroxisome-proliferator-activated $receptor{\gamma}$ ($PPAR{\gamma}$) and CAATT enhancer-binding protein ${\alpha}$ (C/$EBP{\alpha}$) in 3T3-L1 preadipocytes, accompanied by the activation of Wnt/${\beta}$-catenin signaling pathway. Taken together, our findings indicate that silybin is a small-molecule synergist of the Wnt/${\beta}$-catenin signaling pathway and can be used as a controllable reagent for investigating biological processes that involve the Wnt/${\beta}$-catenin signaling pathway.

3D-QSARs Analysis on the Fungicidal Activity with N-phenylbenzenesulfonamide Analogues against Fusarium wilt (Fusarium oxysporum) (N-phenylbenzenesulfonamide 유도체들에 의한 시들음병균(Fusarium oxysporum)의 살균활성에 관한 3D-QSARs 분석)

  • Soung, Min-Gyu;Hwang, Tae-Yeon;Kang, Kyu-Young;Sung, Nack-Do
    • Applied Biological Chemistry
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    • v.51 no.1
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    • pp.38-43
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    • 2008
  • 3D-QSARs on the fungicidal activity with N-phenylbenzenesulfonamide and N-phenyl-2-thienylsul-fonamide analogues (1-34) against Fusarium wilt (Fusarium oxysporum) were discussed quantitatively using CoMFA (comparative molecular field analysis) and CoMSIA (comparative molecular similarity indices analysis) methods, respectively. Generally, the CoMFA models have better predictability and fitness than the CoMSIA models. The fungicidal activities, according to the information of the optimized CoMF A 2 model $(r^2\;_{cv.}=0.523\;&\;r^2\;_{ncv.}=0.956)$, were dependent on the electrostatic field of the N-phenylbenzenesulfonamide analogues. Therefore, from the results of graphical analyses on the contour maps with the optimized CoMFA 2 model, it is expected that the characters of $R_4-substituents$ on the N-phenyl ring as steric and positive charge favor will contribute to the fungicidal activity against Fusarium wilt.

The Turning towards Neo-Endogenous Rural Development of the Farmers Network : The Case of the Regional Agricultural Cluster Scheme in Asan City (농민단체 주도의 신내생적 농촌개발에 관한 연구 -아산시 지역농업 클러스터 정책 사례-)

  • Kim, Tae-Yeon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.15 no.2
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    • pp.902-913
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    • 2014
  • This paper deals with the novel concept of neo-endogenous rural development which has been applied to explain the contemporary features of the European rural development. The notion of neo-endogenous rural development has been emerged in Europe because the pervious dichotomous concepts of exogenous and endogenous development are no longer useful for explaining the relationship between the local actors and the central or regional administrative organisations. The concept argues that the changing situation of rural regions at the initial stages of endogenous development could only be identified by the concept of neo-endogenous perspectives. Therefore, it tries to apply the concept for the Korean rural development policy which is called Regional Agricultural Cluster scheme. Explaining the development processes and the problems of the farmers group which carried out the project in a local level, this paper argues that the severe conflict between the farmers group and the City Office may be a typical incident of the neo-endogenous development. It expresses the power relations between the local groups and the political managing authority. With the case of the Prundle, it concludes that the neo-endogenous development is the essential stage for all the endogenous development to go through as an transitional one.