• Journal of Life Science
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• v.23 no.5
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• pp.650-656
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• 2013

Endothelial protein C receptor (EPCR) plays a pivotal role in augmenting Protein C activation through the thrombin-thrombomodulin complex. EPCR activity is markedly changed by ectodomain cleavage and released as the soluble protein (sEPCR). EPCR shedding is mediated by tumor necrosis factor-${\alpha}$ converting enzyme (TACE). Lycopene found in tomatoes and tomato products has anti-oxidant, anti- cancer and anti-inflammatory effects. However, little is known about the effects of lycopene on EPCR shedding. We investigated this issue by monitoring the effects of lycopene on the phorbol-12-myristate 13-acetate (PMA), tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-$1{\beta}$ and on the cecal ligation and puncture (CLP)-mediated EPCR shedding. Data showed that lycopene potently inhibited the PMA, TNF-${\alpha}$, IL-$1{\beta}$ and CLP-induced EPCR shedding by suppressing TACE expression. Furthermore, lycopene reduced PMA-stimulated phosphorylation of p38, extracellular regulated kinases (ERK) 1/2 and c-Jun N-terminal kinase (JNK). Given these results, lycopene should be viewed as a candidate therapeutic agent for the treatment of various severe vascular inflammatory diseases via inhibition of the EPCR shedding.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.20 no.4
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• pp.187-193
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• 2020

In this study, we wanted to analyze the factors at the national university level that affect college students ' elimination. In addition, national universities, private universities, universities in Seoul and universities outside of Seoul were divided into more college-specific characteristics. Except for leave of absence and departure from school, it was defined as a middle school dropout among changes of students. The data were used for analysis by receiving raw data from "University Alerts," which are operated by the Ministry of Education and the Korean Council for Educational Universities. At the university notification, 222 universities out of the schools classified as "Universities" were utilized for final analysis, and jobs, credits, scholarships, tuition fees, students, independent students, and full-time teachers were secured through multiple education. Overall, the higher the average graduate level and employee-rate the lower the rate of elimination from the middle of college students, the analysis showed. Second, the higher the average tuition fees at private universities, the more negatively affects the rate of elimination of university students. Third, higher tuition fees at universities outside the Seoul metropolitan area have a negative impact on the rate of elimination of students.

• 전기의세계
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• v.20 no.5
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• pp.47-54
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• 1971

전력계통의 주파수변동은 공급력과 수요의 불평형에 의하여 발생되는것으로 이것은 상시 일정속도를 요구하는 제사, 제지, 정밀공업등에 크게 영향을 끼치고 일반 회전부하에서도 효율을 저하시킨다. 한편 사고등으로 인한 주파수의 이상저하는 전력계통의 안정도를 저하시키며 특히 기력발전기의 탈락을 수반할 경우 사고의 파급이 확대되는 경우가 있게 됨으로 이러한 경우가 극력 적을것이 요망된다. 따라서 공급측은 평상시는 시시각각으로 변동하는 수요에 적응해서 공급력을 조정하고 대전원 탈락으로 공급력에 대폭 부족이 발생하는 이상시는 계통주파수를 한도치 이상으로 하여 계통의 안정을 유지하여야 한다. 본 고에서는 전력주파수특성의 개요만을 간단히 설명하고 1968년말 부터 시행한 주파수 특성시험 방법과 그 결과치를 보고코져 한다.

• Proceedings of the KIEE Conference
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• 2003.11a
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• pp.358-360
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• 2003

원자력과 같은 대용량 발전기의 갑작스런 탈락이나 하루 중 아침시간이나 점심시간과 같이 급격한 부하변동이 발생하는 특수 시간대에는 계통의 발전량과 부하량간에 심한 불균형이 발생하게 된다. 이 경우 계통 주파수가 변하여 발전량과 부하량이 자동으로 조절되어 수급의 균형이 이루어지게 되므로 계통이 안정하게 유지된다. 본 논문에서는 실계통 사고사례를 통하여 우리나라 계통에서 대용량 발전기 탈락시 주파수변동에 따른 발전량 및 부하량의 조절특성과 고장당시 계통 발전기들의 응동특성을 소개한다.

• Korean Architects
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• no.7 s.160
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• pp.65-67
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• 1982

• Transactions of the Korean Society of Mechanical Engineers A
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• v.39 no.12
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• pp.1297-1303
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• 2015

The internal chromium plating of a long-axis tube is widely used in military and industrial application, with the thick hard plating formed using a mixed solution of Chromium acid and catalytic $H_2SO_4$. A large-caliber gun can endure a high explosive force as a result of the increased stiffness and wear resistance provided by this internal hard chromium surface. The internal chromium layer of a tube is prone to exfoliation caused by the high kinetic energy of the projectile and high pressure of the explosion. Therefore, we reviewed the plating process. Chromium plating comprises many steps, including the removal of Grease, water cleaning, electrolytic abrasion, etching, plating, water cleaning, and hydrogen brittleness removal. The exfoliated chromium plating layer is affected by the adhesion property of the plating. In particular, the Fe concentration of the electrolyte affects the adhesion property. The optimum Fe concentration for effectively suppressing the exfoliation of the plating layer was established by using a scanning electron microscope to determine the surface roughness, and the effectiveness was proved in an adhesion test, etc.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.36 no.2
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• pp.147-153
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• 1991

In order to clarify the varietal differences of grain shedding in 86 rice varieties with the diverse origin, a bundle of 10 panicles was fallen down on the bottom above 2m height, and several characters related to shattering were investigated. The ratio of grain shedding in the varieties from the Tongil types was the greatest (11. 29%), followed by the native and J aponica types (2.56, 0.17%). The breaking tensile and breaking bending strengths of the primary rachis-branch in the Tongil types were weaker than in the native and Japonica types with mean values of 217g and 20.5g, respectively. The fiber cells length of the primary rachis- branch in the Tongil types were shorter in the native and Japonica types. The ratio of grain shedding was significantly correlated with the breaking tensile and bending strengths of the primary rachis- branch, and fiber cell length.

• Restorative Dentistry and Endodontics
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• v.35 no.1
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• pp.20-23
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• 2010

Mouthguards were used to protect boxers from lip lacerations and other soft tissue injuries in the late 19th century. Now they are used various parts of dental treatment, which are sports protective aid, bleaching tray, orthodontic retainer, implant insertion guide tray, splint and so on. Repeated dislodgement of Class V restoration due to habitual clenching stress should be restored with stress control. Mouthguard can be used as stress relief device. This case describes methods that can relieve occlusal force to teeth by using mouthguard. Satisfactory results can be obtained by using mouthguard for retention of repeated dislodgement Class V restorations. If patients suffered from repeated restorations of Class V due to clenching, mouthguard can be used additional device to relieve the occlusal stress in conservative dentistry.

• Development and Reproduction
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• v.2 no.1
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• pp.81-87
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• 1998

A scanning electron microscopic study on the glochidial encystment and excystment during the development of Anodonta arcaeformis flavotincta on Carassius auratus, a common natural host fish, was carried out. The glochidia were attached to the fins, buccal cavity and gills of the host fish within 30 minutes. In this study, the fins of host fish infected with the glochidia were examined in a time series. The attachment rates of the glochidia on the pectoral fins, caudal fin and pelvic fins of the host fish were 30%, 22%, and 17%, respectively. The glochidia which attached to the fish became encysted within 27 hrs. The process of encystment progressed slowly. Ti took 24 to 27 hours in the formation of the primary cyst, and after 5 to 6 days, the larvae was covered completely with the epithelial cels of the host tissues. The process of detachment of juvenile clam was observed on the 8th day after host infection. Most of the juvenile clams have sloughed from the cyst of the host within 15 days. No significant size difference was observed in the glochidia and the juvenile which were found before attachment and after detachment from the cyst of the host fish.

• Journal of Digital Convergence
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• v.14 no.1
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• pp.453-463
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• 2016

This study examined the relationship among dropout, organizational trust, and intention to transfer in the department affiliated with Physical Education. Data were collected from 480 students in the department affiliated with Physical Education from 6 institutions of a 4-year university located in Seoul, Gyeonggi-do, Incheon, and ChungChong-do. For the research model analysis, a structural equation model and bootstrapping were conducted. Results indicated that the academic domain, the social domain, and the environmental domain of dropout had a positive effect on organizational trust. But the only the academic domain in the relationship between dropout and intention to transfer affected intention to transfer positively. The social domain and the environmental domain were not statistically significant on intention to transfer. Moreover, organizational trust had a positive effect on intention to transfer. Finally, organizational trust partially mediated the path between the academic domain and intention to transfer. It fully mediated the paths between the social domain and the environmental domain and intention to transfer.