• Title/Summary/Keyword: 코호트연구

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Design and Development of the Database for the Korean Genome and Health Study (한국인 유전체역학 정보 DB 설계 및 구축)

  • 양은주;박용철;고인송;오범석;김규찬
    • Proceedings of the Korean Information Science Society Conference
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    • 2003.10b
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    • pp.844-846
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    • 2003
  • 국립보건원 유전체연구소는 안산-안성 지역에 거주하는 45세 이상 69세 이하의 성인을 대상으로 고혈압, 당뇨, 골다공증, 천식, 비만 등 한국인의 총 국민의료비용에서 큰 부분을 차지하는 중요 만성질환에 초점을 맞추어 코호트 연구를 수행하고 있다. 이에 검진대상자의 설문 및 임상검사를 통하여 수집되는 개인식별 데이터, 생활습관 데이터 등의 설문정보와 다양한 임상검사정보에 대한 체계적 저장ㆍ관리와 향후 수행될 대규모 정보 분석을 위해 유전체역학 정보 DB를 설계.구축하였다.

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The incidence of metabolic syndrome and its risk factor in who under went medical check-up in a health promotion center (일개 종합병원 건강검진 수진자들의 대사증후군 발생 수준과 위험요인)

  • Cheon, Hae-Kyung;Lee, Tae-Yong;Kwon, In-Sun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.13 no.3
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    • pp.1186-1193
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    • 2012
  • The purpose of the study is to provide the basic data for preventing and caring cardiovascular disease. The study was performed with the data from the same 1,668 persons who had medical checkup three times from 2004 to 2008 at a health promotion center. The related factors were examined with Cohort Study. The result of the study is as followed, The incidence of metabolic syndrome for the subjects from 2004 to 2008 increased; 0% in 2004, 8.3% in 2006 and 12.0% in 2008. Multiple logistic regression analysis showed that the related factors in the occurrence of metabolic syndrome which changed from the non metabolic syndrome group in 2004 to metabolic syndrome were age, smoking, total cholesterol, ALT, and uric acid etc.

Determinants of Household Debt using a Hierarchical Aging-Period-Cohort Model: Baby-boomers with Middle-Aged & Older Adults (위계적 APC모델을 활용한 가계부채결정원인 분석: 베이비부머세대 포함 중·장년·노년층을 중심으로)

  • Kim, Jeungkun
    • The Journal of the Korea Contents Association
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    • v.17 no.9
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    • pp.396-405
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    • 2017
  • Main purpose of this study is to analyze determinants of household debt among middle and old individuals aged between 32 and 76 that include Korean baby-boomers(born between 1955 and 1963), using a HAPC (Hierarchical Age-Period-Cohort) model and Korean Welfare Panel Study 2006-2016. This study includes 86,056 individuals. Research findings indicate that aging and period effects have statistically significant relationships with household debt levels, however, cohort effects including a baby-boomer generation do not. While household debt increases by 3,530,000 Korean won as age increases by one year, the rate of increase in household debt reduces as individual ages. In addition, employment and health status at the individual level have significant effects on household debt levels. The unemployed are more likely than the employed to have high household debt levels while unhealthy people tend than healthy people to have high household debt levels.

Factors affecting the turnover intention of hospital nurses quarantined in cohort due to the outbreak of COVID-19: Focused on a university hospital (코로나19 확진자 발생으로 코호트격리된 병원간호사의 이직의도 영향요인: 일 대학병원을 중심으로)

  • Lee, Soon-Youl;Han, Suk-Jung
    • Journal of the Korea Convergence Society
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    • v.13 no.4
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    • pp.561-572
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    • 2022
  • This study is a descriptive survey study conducted to identify the factors affecting the turnover intention of hospital nurses who were cohort-isolated due to the outbreak of COVID-19. The data collected from 191 university hospital nurses were analyzed using the IBM SPSS Statistics 23 program by descriptive statistics, t-test, Pearson's correlation analysis, ANOVA, and multiple regression analysis. Among the factors affecting the turnover intention, the higher the infection control job stress (𝛽=.40, p<.001), the lower the support of the boss among social support at work (𝛽=-.21, p=.004). The lower the resilience (𝛽=-.16, p=.016) the higher the turnover intention. The explanatory power of these variables was 25% (Adj. R2=.25, F=16.99, p<.001). In particular, the infection control job stress of hospital nurses who had the entire hospital under cohort-isolated due to the outbreak of COVID-19 was above average. It is necessary to find a way to reduce infection control job stress, and to reduce the negative aspects of the organization and work with the support of the superior to lower the turnover intention. In addition, it is necessary to seek to reduce turnover intention as a program to strengthen resilience to improve resilience.

Predictors of Postpartum Depression: Prospective Cohort Study (산후우울증 관련요인: 전향적 코호트 연구)

  • Youn, Ji Hyang;Jeong, Ihn Sook
    • Journal of Korean Academy of Nursing
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    • v.43 no.2
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    • pp.225-235
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    • 2013
  • Purpose: This prospective cohort study was done to investigate recall bias to antepartum variables measured at postpartum periods and predictors of postpartum depression. Methods: Participants were 215 women who answered a self-administered questionnaire which included demographics, Postpartum Depression Predictors Inventory-Revised and Korean version of Edinburgh Postpartum Depression Scale at antepartum 36-40 weeks and postpartum 2 weeks and 6 weeks. Data were analyzed using kappa, and hierarchical multiple logistic regression. Results: Agreement between antepartum variables at both antepartum and two postpartum periods was relatively high (${\kappa}$=.55- .95). Postpartum depression rates were 36.3% and 36.7% at two follow-up points. In hierarchical multiple logistic regression analysis, prenatal depression (OR=4.32, 95% CI: 1.41-13.19; OR=5.19, 95% CI: 1.41-19.08), social support (OR=1.40, 95% CI: 1.18-1.66; OR=1.27, 95% CI: 1.06-1.53) and maternity blues (OR=4.75, 95% CI: 1.89-11.98; OR=4.22, 95% CI: 1.60-11.12) were commonly associated with postpartum depression at two follow-up points. Child care stress (OR=1.85, 95% CI: 1.01-3.37) was only associated with postpartum depression at 2 weeks postpartum and pregnancy intendedness (OR=1.57, 95% CI: 1.09-2.27) was only associated with postpartum depression at 6 weeks postpartum. Conclusions: The results indicate a need to apply nursing interventions such as prenatal education and counseling with families from antenatal period.

Cohort Study on Age at Menopause and Mortality - Kangwha Cohort Study - (폐경 연령과 사망력과의 관계에 대한 코호트 연구 - 강화 코호트 연구 -)

  • Hong, Jae-Seok;Yi, Sang-Wook;Jee, Sun-Ha;Sohn, Tae-Yong;Ohrr, Hee-Choul
    • Journal of Preventive Medicine and Public Health
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    • v.34 no.4
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    • pp.323-330
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    • 2001
  • Objective : To examine the association between age at menopause and mortality in a population-based sample of women in Kangwha, Korea. Methods : From the Kangwha Cohort, followed-up from 1985 to 1999, the data of the over 55 year old female group(n=3,596) was used in this study to examine the association between age at menopause and mortality. We calculated the all causes mortality risk ratio and the cancer mortality risk ratio by age at menopause grouping using the Cox Proportional Hazards Model with adjustments for age, BMI, smoking, education, chronic disease, self-rated health status, alcohol consumption and age at first birth. Result and conclusion : Compared to women who had menopause at 45-49 years, the all causes mortality risk ratio was 1.24 for women with menopause at less than 40 years(95% CI=1.01-1.53) and 1.05 for women with menopause at over 50 years(95% CI=0.92-1.20). Also, compared to women who had menopause at 45-49 years, the cancer mortality risk ratio was 1.53 for women with menopause at less than 40 years(95% CI=0.78-2.98) and 1.17 for women with menopause at over 50 years(95% CI=0.77-1.80).

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Estimating a Precautionary Saving Motive under Consumption Uncertainty (소비의 불확실성에 따른 예비적 저축 동기 추정)

  • Hwang, Jin-tae;Kim, Sung-min
    • Economic Analysis
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    • v.26 no.3
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    • pp.48-70
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    • 2020
  • Using data from the Household Income and Expenditure Survey over the period 1994-2016, we estimate the coefficient of relative prudence in order to capture precautionary saving motive. To do this, we adopt a cohort approach, where we transform such microdata into sample cohort means. Together with initial income involving liquidity constraint, we estimate the relative prudence derived from the Euler equation. The two-stage least-squares (2SLS) between estimate of it obtained from the cohort panel data analysis is too small for the existence of precautionary saving motive, as in previous studies, while the 2SLS random effects estimate is so reasonable. Moreover, the liquidity-constrained cohorts tend to be more sensitive to uncertainty, relative to the unconstrained ones.

The Comorbidity of Anxiety Disorder in Depressed Patients : A CRESCEND(Clinical Research Center for Depression in Korea) Cohort Study (우울증 환자에서 불안장애의 동반이환 : 우울증 임상연구센터 코호트연구)

  • Sakong, Jeong-Kyu;Lee, Do-Yun;Suh, Ho-Suk;Sung, Hyung-Mo;Kim, Jung-Bum;Jung, Young-Eun;Lee, Min-Soo;Kim, Jae-Min;Jo, Sunjin
    • Mood & Emotion
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    • v.9 no.1
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    • pp.30-36
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    • 2011
  • Purpose : Anxiety disorder and depressive disorder are often comorbid with each other, and the comorbidity is associated with poorer psychiatric outcome, resistance to treatment, increased risk for suicide, greater chance for recurrence. We aimed to investigate the comorbidity of anxiety disorder in Korea. Method : Subjects were total of 867 depressed patients recruited CRESCEND-K multicenter trial. We used SCID (Structured Clinical Interview for DSM - IV) to find comorbidity of anxiety disorders in depressed patient. Results : Of 867 patients, total 8.2% had anxiety disorder. Proportion of anxiety disorder Not Otherwise Specified was 3.5%, panic disorder was 1.7%, generalized anxiety disorder was 1.1%, post traumatic stress disorder was 0.9%, obsessive compulsive disorder was 0.6%, social phobia was 0.4%. Conclusion : In this study, anxiety disorder in depression were measured at a low comorbidity rate in compare to previous studies. Selection bias, use of antidepressants at registration, severity of depression symptoms, and point of SICD administration seems to have affected these results. It is probable that comorbidity evaluation would be more precise if shorter, structured interviews such as M. I.N.I.-Plus were used during first clinical interview for depression diagnosis.