• Journal of Biomedical Engineering Research
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• v.41 no.1
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• pp.62-66
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• 2020

Controlled drug release is important for effective treatment of cancer. Poly(DL-lactide-co-glycolide) acid (PLGA) is a Food and Drug Administration (FDA) approved polymer and have been extensively studied as drug delivery carriers with biodegradable and biocompatible properties. However, PLGA drug delivery carriers are limited due to the initial burst release of drug. Certain drugs require an early rapid release, but in many cases the initial rapid release can be inefficient, reducing therapeutic effects and also increasing side effects. Therefore, sustained release is important for effective treatment. Poly Lactic Acid stereo complex (PLA SC) is resistant to hydrolysis and has high stability in aqueous solutions. Therefore, in this work, PLGA based discoidal polymeric particles are modified by Poly Lactic Acid stereocomplex (PLAsc DPPs). PLAsc DPPs are 3 ㎛ in diameter, also showing a relatively sustained release profile. Fluorescein 5(6)-isothiocyanate (FITC) released from PLAsc DPPs was continuously observed until 38 days, which showed the initial release of FITC from PLAsc DPPs was about 3.9-fold reduced as compared to PLGA based DPPs at 1 hour.

• Journal of Institute of Control, Robotics and Systems
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• v.1 no.1
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• pp.63-70
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• 1995

퍼지논리제어기는 산업응용에 광범위하게 연구되고 있으며, 계속적으로 사용되고 있다. 그러나 퍼지집합의 조정을 통해 최적규칙을 구축하기 위하여, 시행착오에 의한 매우 능숙한 기술이 요구된다. 이 논문에서는 첫째로, 퍼지논리제어기와 기존의 PID 제어기로 구성된 하이브리드 퍼지제어기를 제안한다. 즉, 시스템의 제어 입력은 퍼지변수로서, 과도상태에서의 FLC출력과 정상상태에서의 PID 출력의 컨벡스(convex) 결합이다. 둘째로, 간략추론법과 개선된 컴플렉스방법을 이용한 강력한 자동동조알고리즘이 퍼지논리제어기의 성능을 자동적으로 개선하기 위하여 사용된다. 이방법은 오차변화율및 제어출력의 제한조건에 의하여, 언어제어규칙, 퍼지계수(scaling factor), PID계수, 하이브리드 퍼지논리제어기의 하중계수의 최적값을 자동적으로 추정한다. 시뮬레이션은 시간지연 플랜트및 하수처리시스템의 활성오니공정과 같은 비선형 플랜트에서 실행되고, 시스템의 성능은 평가지수 ITAE로 평가된다.

• Journal of Korea Water Resources Association
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• v.36 no.5
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• pp.851-861
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• 2003

Snow accumulation and snow melt was simulated and included in the computation of the watershed runoff for Soyanggang Dam and Chungju Dam. A modified Tank Model was used for the simulation, which has three serial tanks and a pulse response function. The model parameters were estimated through the global optimization method of Shuffled Complex Evolution-University of Arizona (SCE-UA). A watershed was divided into four zones of elevation. The temperature decrease of the zones was a rate of -0.6$^{\circ}C$/100m. Almost all precipitation from December to February become accumulated as snow, and then the snow melts and runs off from March to April. The average runoff with snow melt was greater than the average runoff without snow melt during the period from March to April. The improved amount from snow melt simulation was about one fifth of the observed one for Soyanggang Dam. The increased amount for Chungju Dam was about one fourth of the observed average runoff during the same period. Although the watershed runoff was simulated including snow melt, it was less than the observed one for both of the dams.

• Journal of the Korean Institute of Intelligent Systems
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• v.5 no.4
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• pp.41-55
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• 1995

In this paper, an optimal idenfication method using fuzzy-neural networks is proposed for modeling of nonlinear complex systems. The proposed fuzzy-neural modeling implements system structure and parameter identification using the intelligent schemes together wlth optimization theory, linguistic fuzzy implication rules, and neural networks(NNs) from input and output data of processes. Inference type for this fuzzy-neural modeling is presented as simplified inference. To obtain optimal model, the learning rates and momentum coefficients of fuzzy-neural networks(FNNs) are tuned automatically using improved modified complex method and modified learning algorithm. For the purpose of its application to nonlinear processes, data for route choice of traffic problems and those for activateti sluge process of sewage treatment system are used for the purpose of evaluating the performance of the proposed fuzzy-neural network modeling. The results show that the proposed method can produce the intelligence model with higher accuracy than other works achieved previously.

• Journal of the Korean Ceramic Society
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• v.51 no.4
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• pp.295-299
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• 2014

Electrical conductivities of complex perovskites, layered perovskite and Sr doped layered perovskite oxides were measured and analyzed for cathode materials of Intermediate Temperature-operating Solid Oxide Fuel Cells (IT-SOFCs). The electrical conductivities of $Sm_{1-x}Sr_xCoO_{3-\delta}$ (x = 0.3 and 0.7) exhibit a metal-insulator transition (MIT) behavior as a function of temperature. However, $Sm_{0.5}Sr_{0.5}CoO_{3-\delta}$ (SSC55) shows metallic conductivity characteristics and the maximum electrical conductivity value compared to the values of $Pr_{0.5}Sr_{0.5}CoO_{3-\delta}$ (PSC55) and $Nd_{0.5}Sr_{0.5}CoO_{3-\delta}$ (NSC55). The electrical conductivity of $SmBaCo_2O_{5+\delta}$ (SBCO) exhibits a MIT at about $250^{\circ}C$. The maximum conductivity is 570 S/cm at $200^{\circ}C$ and its value is higher than 170 S/cm over the whole temperature range tested. $SmBa_{0.5}Sr_{0.5}Co_2O_{5+\delta}$ (SBSCO), 0.5 mol% Sr and Ba substituted at the layered perovskite shows a typically metallic conductivity that is very similar to the behavior of the SSC55 cathode, and the maximum and minimum electrical conductivity in the SBSCO are 1280 S/cm at $50^{\circ}C$ and 280 S/cm at $900^{\circ}C$.

• Journal of the Korean Institute of Intelligent Systems
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• v.6 no.2
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• pp.81-89
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• 1996

A design method of fuzzy modeling is presented for the model identification of route choice of traffic problems.The proposed fuzzy modeling implements system structure and parameter identification in the eficient form of""IF..., THEN-.."", using the theories of optimization theory, linguistic fuzzy implication rules. Three kinds ofmethod for fuzzy modeling presented in this paper include simplified inference (type I), linear inference (type 21,and proposed modified-linear inference (type 3). The fuzzy inference method are utilized to develop the routechoice model in terms of accurate estimation and precise description of human travel behavior. In order to identifypremise structure and parameter of fuzzy implication rules, improved complex method is used and the least squaremethod is utilized for the identification of optimum consequence parameters. Data for route choice of trafficproblems are used to evaluate the performance of the proposed fuzzy modeling. The results show that the proposedmethod can produce the fuzzy model with higher accuracy than previous other studies -BL(binary logic) model,B(production system) model, FL(fuzzy logic) model, NN(neura1 network) model, and FNNs (fuzzy-neuralnetworks) model -.fuzzy-neural networks) model -.

• Cross-Cultural Studies
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• v.27
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• pp.167-195
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• 2012

A Chinese female writer Linhaiyin(林海音) and Chengnanjiushi(城南舊事), her representative work, have never been studied in Korea before although she and her literary works stand high and are well known in the history of the modern Chinese literature. Thus, in this paper, I analyze her and her novels included in Chengnanjiushi and study their literary value and meaning. To analyze and study them, I mainly consider novels Anhuiguan, Womenkanhaiqu, Lanyiniang, $L{\acute{\ddot{u}}}dagunr$, and Babadehuarluole included in Chengnanjiushi. Firstly, I look into her attitude and mode to observe children and women's life as a writer. Such attitude and mode succeeded to the spirit of the '5.4 literature'. Secondly, I evaluate Linhaiyin's 'Both sides complex' and its value in the history of literature. From this evaluation, the meaning of Linhaiyin's literature is highlighted. She was free from 'Both sides complex' occurred due to the circumstance of the times and played a role of a bridge so as not to break off literature of China and Taiwan. When her and her works are evaluated, this is one of the most important values. The characteristic of her writing mode is that she did not seek a compelling climax, a surprising reversal, or an exclusive plot or character in her works. In her works, plain description or unwitting conversation and story often imply deep meanings. Thus, at unexpected moment after reading her novels, readers truly listen to deep resonance for her attitude and mode to observe people's life. This is exactly her potential energy that makes readers sink into her literary world regardless of time and space.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.10 no.11
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• pp.3500-3505
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• 2009

Sixteen moderate atopic dermatitis patients were treated with applying toner and cream using estern medical herbs[Estern medical complex(Radix Glycyrrhizae, Radix Angelicae Dahuricae, Rhizoma Ligustici Chuanxiong, Fructus ponciri Seu Aurantii Immaturus, Radix Rehmanniae Praeparata, Radix Puerariae, Rhizoma Corydalis), Cypress, Green tea, Radix Astragali, Red ginseng, Syrup ferment, Apple ferment filtrate] on the atopic area 2-3 times per day for 6 weeks. After 6 weeks of study, the result was a decrease in SCORAD index($26.9{\pm}11.8$ to $14.9{\pm}9.7$(p<0.05)), IgE($641.9{\pm}1294.6$ to $565.8{\pm}1076.8$), Eosinophil count($246.7{\pm}203.5$ to $203.3{\pm}130.7$(p<0.05)) and TEWL($16.7{\pm}5.1$ to $15.4{\pm}8.7$(p<0.05)). And skin hydration was increased($36.6{\pm}10.0$ to $44.0{\pm}10.3$(p<0.01)) maintaining skin pH level. The patient;s and physician's global assessment also improved. Therefore, estern medical herbs may play a role in treatment of atopic dermatitis.

• Journal of Popular Narrative
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• v.26 no.4
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• pp.9-41
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• 2020

Park Jong-won's debut film "Guro Arirang," based on a short story of the same title by Lee Moon-yeol, is the first commercial film to deal with labor struggles from a worker's point of view in the wake of the 1987 democratic movement, and a pioneering work in terms of representing female workers the Korean cinema has traditionally turned away from. In this film Park Jong-won tried to win the sympathy of the middle class for labor movement in spite of the red scare which still stood firm in the Korean society at that time. To convey its progressive message in a form acceptable to the middle class public, the film portrays labor issues in the light of universal humanity and ethics, not in terms of class hostility or struggle. Park Jong-won calls this point of view "common sense of normal people" and emphasizes its universality and objectivity. This study critically examines the cinematic strategies to deal with labor issues in a form acceptable to the public in a conventional and commercial film and the ideological implications of the "common sense of normal people" reflected in such strategies. The first chapter of the study reveals that the film destroys the irony of the original story and reduces the complex constellation of the characters to the conflict between pure good and evil, creating a melodramatic composition in which the good falls victim to evil. The tragedies suffered by the workers in the film are of course intended to arouse the audience's strong sympathy and solidarity with them. The second chapter shows that the film's various scenes and episodes converge on the them of compassion and grief, and are mostly based on cultural and real experiences and events that caused great public sensations at that time. Especially in the last decisive scene of the movie, the memory of the June 1987 uprising is strongly recalled. So "Guro Arirang" can be seen as a patchwork of proven cases of compassion and grief. The third chapter examines the implications of the scene where the workers turn back demands for wages and put the issues of human treatment and trust to the forefront at the crucial moment of their struggle. It appeals to universal moral values and sentiments that everyone has to acknowledge and removes the political dimension from the workers' campaign. While the film tends to become a pure story of humanity marginalizing irreconcilable conflicts of class interest, the workers fall to the position of passive victims who can be deeply sympathetic on the one hand, and on the other, are idealized as leaders with noble attitude keeping themselves aloof from the hard reality. As a result, the movie loses its realistic ground and weakens its narrative probability. The scenes reminiscent of the 1987 uprising which evoke the solidarity between working and middle class fail to integrate harmoniously into the whole story of the film and remain only as fragmentary parts of the patchwork of compassion and grief.

• Korean Journal of Culture and Arts Education Studies
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• v.5 no.1
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• pp.97-147
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• 2010

Under the recent trend of globalization, a new proposal on education has not been able to avoid the request for multi-cultural trend. Furthermore, education has been exposed to circumstances which are far different from the previous situations in which global cooperation and intercultural understanding have been more emphasized. 'Educational Nomadism'is a metaphor of creating new value and significance of education. In fact, transnational education which could be a crisis and opportunity at the same time has recently been the mainstream throughout the world. In terms of education, Korea has encountered base hollowing-out in which excessive dependence on the US education and autonomous education coexist. In fact, the world has spent a lot of time and money to have better educational background on a resume through redundant expense by the government and parents. Under this critical situation, it's urgent to change Korea's modern education into a creative educational system in connection with an advanced foreign educational system and further develop the advantage of Korea's education. A parent's investment in his/her child is a support to create new culture as well as an assistance for hope and better future of Korean education. A new direction of parents' education fever that has opened a door to global communitas can stir up infinite potential through which the flow of education fever can be changed to the resources of new civilization. The global cooperation and efforts for communitas means the communication with this world. Through this communication, the culture in which people are forced to zero-sum competition can leap into the education for change of civilization which creates pleasure of self sufficiency and donation.