• Korean Journal of Food Science and Technology
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• v.53 no.3
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• pp.278-289
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• 2021

The rapid aging of society has led to a surge in cognitive dysfunction in the elderly. As there is limited evidence for the development of dementia in medicine, a shift in focus on prevention strategies using bioactive compounds in food is required. This systematic review evaluated the effects of various bioactive compounds on age-associated cognitive decline. The literature was searched for terms related to bioactive compounds in cognitive decline and article selection was limited to clinical randomized controlled trials for a single bioactive compound. We identified 21 studies that evaluated the strength of the evidence. ω-3 fatty acids and vitamin B presented a strong evidence level, whereas vitamin D and E, anserine/carnosine, and chromium were defined as having moderate levels of evidence. ω-3 fatty acids relieved cognitive decline and reduced amyloid β-related protein accumulation. Vitamin B decreased homocysteine levels, which is accompanied by alleviation of cognitive function. In conclusion, ω-3 and vitamin B have the potential to improve age-associated cognitive decline.

• The Korean Journal of Applied Statistics
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• v.33 no.5
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• pp.555-567
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• 2020

Hypertension has a steadily increasing incidence rate as well as represents a risk factors for secondary diseases such as cardiovascular disease. Therefore, it is important to predict the incidence rate of the disease. In this study, we constructed nomograms that can predict the incidence rate of hypertension. We use data from the Korean National Health and Nutrition Examination Survey (KNHANES) for 2013-2016. The complex sampling data required the use of a Rao-Scott chi-squared test to identify 10 risk factors for hypertension. Smoking and exercise variables were not statistically significant in the Logistic regression; therefore, eight effects were selected as risk factors for hypertension. Logistic and Bayesian nomograms constructed from the selected risk factors were proposed and compared. The constructed nomograms were then verified using a receiver operating characteristics curve and calibration plot.

• Journal of Yeungnam Medical Science
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• v.27 no.1
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• pp.27-36
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• 2010

Purpose : The purpose of this study was to find out cognitive function of the patients with subjective memory complaint. Material and Methods : From March 1st 2005 to May 31st 2009, 155 normal individuals without any medical illness who visited Yeungnam University Hospital to undergo medical checkup with neurocognitive test was enrolled, and checked by using Cognitive Assessment & Reference Diagnostic System. Results : 107 of the patients had normal cognitive function, 21 patients (about 15%) were diagnosed with dementia, and 10 patients (about 7%) were diagnosed with considerable psychiatric illness, such as depression, anxiety disorder, adjustment disorder. In amnesia, agnosia, aphasia, attention, calculation, dysexecution, Dementia group and Psychiatric illness group has worse score than Normal individuals group. But, in apraxia, Dementia group has worse score than Psychiatric illness group and Normal individual group. Conclusion : Because the patients with subjective memory complaint can be diagnosed as any psychiatric illness as well as dementia, sensitive screening test and early psychiatric approach is needed.

• Journal of Oriental Neuropsychiatry
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• v.12 no.2
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• pp.185-191
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• 2001

Objectives: This study aimed to evaluate the usefulness as a screening test of Clock Drawing Test(CDT) compared with the standard K-DRS in probably dementia. Methods: The subjects for this study consisted of 19 elderly persons who visited to the outpatient department of Oriental Neuropsychiatry of the Kyunghee Oriental hospital. They received the K-DRS and the Clock Drawing Test. Three observers evaluated them with circle, numbers, hands. Inter-rater reliability of scores from Clock Drawing Test was assessed and Pearson correlation coefficients were used to examined the relationships between scores from Clock Drawing Test and K-DRS. Results: Correlations between individual raters was highly significant (r= .957, .974, and .970, respectively: p<.001). There was stastically significant correlations between K-DRS and CDT scores (r= 0.849, p<.001). Conclusions: The CDT can be rated reliably by observers and correlations between CDT and K-DRS is significantly high. We confirmed the usefulness of CDT as simple, easily administered, low cost, and reliable general screening test for dementia.

• Research in Community and Public Health Nursing
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• v.23 no.4
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• pp.446-450
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• 2012

Purpose: This study is exploratory research to check the survey instrument KDSQ-C used to measure cognition for agreement between the elderly and their caregivers. Methods: Elderly persons from 170 families, who are aged over 65, have never been diagnosed with dementia, and who have caregivers in S City and K City were randomly selected by their nurses. A survey was conducted in the time from September to November, 2009 through personal interviews using a questionnaire. Results: In terms of consistency among items, there was high consistency (0.813) in the responses regarding complex task competence for the statement 'it is hard to reach a destination alone with public transportation'. There was relatively low consistency (0.63) in the responses regard memory for the statement 'they forget an appointment'. When the subject elderly and caregiver live together, as when their children or spouses responded, consistency was greater than when the caregiver lived in a different home. Conclusion: KDSQ-C showed high agreement in measurement between the subject elderly and their caregivers, demonstrating that it can be used as a measurement scale for cognition which can be directly applied to the subject elderly.

• Korean Journal of Food Science and Technology
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• v.52 no.5
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• pp.450-458
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• 2020

The purpose of this study was to conduct a systematic review of the current published research related to improvement in cognitive function. A systematic search was performed in three bibliographic databases (PubMed, Cochrane Library, and EMBASE) using "dementia", "memory", "food", "diet", and "nutrition" as keywords. Meal management intervention, including Dietary Approaches to Stop Hypertension (DASH) diet, Mediterranean (Med) diet, Diet Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet, and other studies, was also included in the analysis. Through extensive screening, 21 articles, out of 2101 papers retrieved, were used for the final systematic review. The methodological quality of the randomized controlled clinical trials (RCTs) was assessed using the Cochrane Risk of Bias tool. These articles recommended vegetables, fruits, whole grains, olive oil, fish, berries, nuts, and beans. In conclusion, this study suggests the potential use of meal management to improve cognitive function.

• Journal of the Korean Orthopaedic Association
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• v.56 no.4
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• pp.305-309
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• 2021

Purpose: This study analyzed the increase in disposal rate of femoral heads in the bone bank of a single hospital from medical disease and drug history, as assessed by the Korean health insurance review and assessment service. Materials and Methods: The disposal rate and cause of 340 femoral heads were analyzed according to the regulations of the bone bank based on the standard model of the Ministry of food and drug safety. Results: One hundred and seven (33%) of 323 femoral heads collected from 2009 to 2018, and 65 (46%) of 142 femoral heads collected from 2015 to 2018 were discarded. The most common causes were related to the history of dementia and the administration of radioisotope for nuclear medicine. Conclusion: The current methods and screening tools can lead to errors in disposing of the available tissues in a bone bank. Thus, improved standards and screening methods are needed.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.10 no.1
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• pp.100-111
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• 2011

u-City(ubiquitous city) pursuing competitiveness of city and improvement the quality of life needs high cost to build and operate it. But not all people get a benefit by u-City. It is important that low-income people have experienced information divide gain practical benefits in u-City. In this paper, first we selected suitable item of u-service for low-income people and then drew a order of priority using AHP method about legal and institutional conditions, possibility of technical realization, and the generalization. As a result, we prioritize to u-service for low-income people, that is the order is prevention for missing a dotard, safety of street, and information providing about job and employment.

• Journal of the Korea Convergence Society
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• v.11 no.6
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• pp.203-208
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• 2020

This study examined whether Mild Cognitive Impairment (MCI) is related to the reduction of specific memory among linguistic memory and visuospatial memory, and to identify the most predictive index for discriminating MCI from normal elderly. The subjects were analyzed for 189 elderly (103 healthy elderly, 86 MCI). The verbal memory was used by the Seoul Verbal Learning Test. visuospatial memory was measured using the Rey Complex Figure Test. As a result of multiple logistic regression, verbal memory and visuospatial memory showed significant predictive performance in discriminating MCI from normal elderly. On the other hand, when all the confounding variables were corrected, including the results of each memory test, the predictive power was significant in distinguishing MCI from normal aging only in the immediate recall of verbal memory, and the predictive power was not significant in the immediate recall of visuospatial memory. This result suggests that delayed recall of visuospatial memory and immediate recall of verbal memory are the best combinations to discriminate memory ability of MCI.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.9
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• pp.3973-3982
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• 2012

The purpose of this study was to identify cognitive impairment and it's related factors of the elderly in long term care facilities. The participants of this study were 229 residents of five nursing homes. Data were analyzed using two sample t-test, ${\chi}^2$-test, and logistic regression. The results revealed eight factors related to cognitive impairment: gender(OR=2.41, p=.035), age(75-84: OR=3.26, p=.002, Over 85: OR=4.46, p<.001), living with family before admission(OR=2.17, p=.015), hearing(OR=8.88, p=.004), family history of dementia(OR=4.39, p=.009), ADL(OR=0.82, p<.001), hypertension(OR=4.07, p<.001), and diabetes(OR=3.42, p=.001). Based on the findings of this study, continuous nursing intervention focused on adjustable factors would be helpful in order to improve nursing home elderly people's quality of life.