• Title/Summary/Keyword: 층화

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Study on Effects of Population Stratification on Haplotype Trend Test in Case-Control Studies (환자-대조군 연구에서 인구집단 층화가 일배체형 경향성 검정에 미치는 영향)

  • Kim, Jin-Heum;Kang, Dae-Ryong;Lim, Hyun-Sun;Nam, Chung-Mo
    • The Korean Journal of Applied Statistics
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    • v.22 no.5
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    • pp.1085-1096
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    • 2009
  • Population stratification can cause spurious associations between genetic markers and disease locus. In order to handle this population stratification in haplotype-based case-control association studies, we added population indicators as covariates to the haplotype trend regression model proposed by Zaykin et al. (2002). We investigated through simulations how both population stratification and measurement error in the estimation of true population of each individual affect type I error probabilities of the association tests based on both Zaykin et al.'s (2002) model and the proposed model. Based on those results, in the situation that there exists population stratification but there is no error in population classification of each individual, our proposed model does satisfy a type I error probability whereas Zaykin et al.'s (2002) model does not. However, as the measurement error increases, a type I error probability of our model correspondingly becomes larger than a nominal significance level. It implies that as long as uncertainty in the estimation of true population of each individual still remains, it is nearly impossible to avoid false positive in case-control association studies based on haplotypes.

Mean Estimation in Two-phase Sampling (이중추출에서 모평균 추정)

  • 김규성;김진석;이선순
    • The Korean Journal of Applied Statistics
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    • v.14 no.1
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    • pp.13-24
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    • 2001
  • In this paper, we investigated mean estimation methods in two-phase sampling. Under the fixed expected cost we reviewed the optimal sample sizes, minimum variances and approximate unbiased variance estimators for usual ratio estimator, stratified sample mean with proportional allocation and Rao's allocation of the second phase sample. Also we proposed combined ratio estimator, which uses both ratio estimation and stratification and derived optimal sample size, minimum variance and unbiased variance estimator. Through a limited simulation study, we compared estimators by design effects and came to know that ratio estimator is more efficient than stratified sample mean in some cases and inefficient in the other cases, but combined ratio estimator is more efficient than others in most cases.

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Determination of the Optimal Cutoff Point using Adjusted Stratum-Specific Likelihood Ratios when Disease Verification is subject to Verification Bias (선택편향이 존재할 때, 수정 층화우도비를 이용한 최적절사점의 결정)

  • Kim, Hu-Nam;Park, Yong-Gyu
    • The Korean Journal of Applied Statistics
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    • v.20 no.3
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    • pp.515-530
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    • 2007
  • Stratum-specific likelihood ratio, which is ratio of the sensitivity to 1-the specificity in each stratum of the test, could be biased if the sensitivity and specificity of diagnostic test are affected by verification bias. Therefore, the optimal cutoff point determined by biased stratum-specific likelihood ratios is incorrect. In this study, we derived adjusted stratum-specific likelihood ratios using the adjusted sensitivity and specificity, and obtained the adjusted optimal cutoff point. The influence of the verification bias on the optimal cutoff point was described through the relation between adjusted and unadjusted stratum-specific likelihood ratios.

A Post Stratification and Calibration under the Unit Nonresponse (단위 무응답 하에서 사후층화와 보정에 관하여)

  • 손창균;홍기학;이기성
    • Proceedings of the Korean Association for Survey Research Conference
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    • 2001.06a
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    • pp.57-70
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    • 2001
  • In this paper we consider a various estimation methods including the post-stratification estimation, regression estimation and calibration estimation or a generalized raking estimation under a unit nonresponse. All of them have a common type of calibration estimation based on the post-stratification for a categorical auxiliary variables.

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A Study on the Multivariate Stratified Random Sampling with Multiplicity (중복수가 있는 다변량 층화임의추출에 관한 연구(층별로 독립인 경우의 배분문제))

  • Kim, Ho-Il
    • Journal of the Korean Data and Information Science Society
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    • v.10 no.1
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    • pp.79-89
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    • 1999
  • A counting rule that allows an element to be linked to more than one enumeration unit is called a multiplicity counting rule. Sample designs that use multiplicity counting rules are called network samples. Defining a network to be a set of observation units with a given linkage pattern, a network may be linked with more than one selection unit, and a single selection unit may be linked with more than one network. This paper considers allocation for multivariate stratified random sampling with multiplicity.

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Numerical Study on the Thermal Stratification Behavior in Underground Rock Cavern for Thermal Energy Storage (TES) (열에너지 저장을 위한 지하 암반공동 내 열성층화 거동에 대한 수치해석적 연구)

  • Park, Do-Hyun;Kim, Hyung-Mok;Ryu, Dong-Woo;Choi, Byung-Hee;SunWoo, Choon;Han, Kong-Chang
    • Tunnel and Underground Space
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    • v.22 no.3
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    • pp.188-195
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    • 2012
  • Using a computational fluid dynamics (CFD) code, FLUENT, the present study investigated the thermal stratification behavior of Lyckebo storage in Sweden, which is the very first large-scale rock cavern for underground thermal energy storage. Heat transfer analysis was carried out for numerical cases with different temperatures of the surrounding rock mass in order to examine the effect of rock mass heating due to periodic storage and production of thermal energy on thermal stratification and heat loss. The change of thermal stratification with respect to time was quantitatively examined based on an index of the degree of stratification. The results of numerical simulation showed that in the early operational stage where the surrounding rock mass was less heated, the stratification of stored thermal energy was rapidly degraded over time, but the degradation and heat loss tended to reduce as the surrounding rock mass was heated during a long period of operation.

Stratification Method Using κ-Spatial Medians Clustering (κ-공간중위 군집방법을 활용한 층화방법)

  • Son, Soon-Chul;Jhun, Myoung-Shic
    • The Korean Journal of Applied Statistics
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    • v.22 no.4
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    • pp.677-686
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    • 2009
  • Stratification of population is widely used to improve the efficiency of the estimation in a sample survey. However, it causes several problems when there are some variables containing outliers. To overcome these problems, Park and Yun (2008) proposed a rather subjective method, which finds outliers before $\kappa$-means clustering for stratification. In this study, we propose the $\kappa$-spatial medians clustering method which is more robust than $\kappa$-means clustering method and also does not need the process of finding outliers in advance. We investigate the characteristics of the proposed method through a case study used in Park and Yun (2008) and confirm the efficiency of the proposed method.

A Sampling Design of the Non-consignment Fishery Products (수산물 비계통 생산량 조사를 위한 표본설계 연구)

  • 박진우
    • The Korean Journal of Applied Statistics
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    • v.12 no.1
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    • pp.1-15
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    • 1999
  • 수산물 비계통 생산량 조사는 수산물 생산량 조사 중 어가부분에서 비계통 출하된 양에 대한 표본조사이다. 본연구는 1995년 어업 총조사 자료에 근거하여 새로운 표본 설계를 제안하는 것을 목적으로 한다. 표본은 층화 2단 집락 추출방식에 의해 추출되었으며 층화변수로는 어업조사구 내의 일반어류 어가 비율을 사용하였다.

Thermal Stratification and Heat Loss in Underground Thermal Storage Caverns with Different Aspect Ratios and Storage Volumes (지하 열저장 공동의 종횡비와 저장용량에 따른 열성층화 및 열손실)

  • Park, Dohyun;Ryu, Dong-Woo;Choi, Byung-Hee;Sunwoo, Choon;Han, Kong-Chang
    • Tunnel and Underground Space
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    • v.23 no.4
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    • pp.308-318
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    • 2013
  • Thermal stratification in heat stores is essential to improve the efficiency of energy storage systems and deliver more useful energy on demand. It is generally well known that the degree of thermal stratification in heat stores varies depending on the aspect ratio (the height-to-width ratio) and size of the stores. The present study aims to investigate the effect of the aspect ratio and storage volume of rock caverns for storing hot water on thermal stratification in the caverns and heat loss to the surroundings. Heat transfer simulations using a computational fluid dynamics code, FLUENT were performed at different aspect ratios and storage volumes of rock caverns. The variation of thermal stratification with respect to time was examined using an index to quantify the degree of stratification, and the heat loss to the surroundings was evaluated. The results of the numerical simulations demonstrated that the thermal stratification in rock caverns was improved by increasing the aspect ratio, but this effect was not remarkable beyond an aspect ratio of 3-4. When the storage volume of rock caverns was large, a higher thermal stratification was maintained for a relatively longer time compared to caverns with a small storage volume, but the difference in thermal stratification between the two cases tended to decrease as the aspect ratio became larger. In addition, the numerical results showed that the heat loss to the surrounding rock tended to increase with an increase in aspect ratio because the surface area of rock caverns increased as the aspect ratio became larger. The total heat loss from multiple small caverns with a reduced storage volume per cavern was larger compared to a single cavern with the same total storage volume as that of the multiple caverns.

Selection of Stratification Variables Under a New Sampling Frame : A Case Study for the Korea National Tourism Survey (계속조사 표본설계에서 추출틀 변경에 따른 층화변수 선정: 국민여행실태조사 사례연구)

  • Park, Hyeon-Ah;Park, Seung-Hwan;Jeon, Jong-Woo;Park, Jin-Woo
    • Survey Research
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    • v.11 no.3
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    • pp.103-114
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    • 2010
  • It is difficult to obtain the population information of target variables when a new sampling design for successive survey is executed. In a research of the Korea National Tourism Survey, we propose a method for selection of efficient stratification variables which are found in a combination of a existing sample data and a new frame list. At first, if there isn't common identification number between the frame list and the sample data, we find a device to substitute for absence of identification number. At second, we suggest a method to search stratification variables correlated with target variables using statistical methods like regression analysis.

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