• Investigative Magnetic Resonance Imaging
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• v.16 no.2
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• pp.136-141
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• 2012

Purpose : To investigate the pharmacologic modulation of motor task-dependent physiologic responses by antiplatelet agent, clopidogrel, during hand motor tasks in healthy subjects. Materials and Methods: Ten healthy, right-handed subjects underwent three functional magnetic resonance (fMRI) sessions: one before drug administration, one after high dose drug administration and one after reaching drug steady state. For the motor task fMRI, finger flexion-extension movements were performed. Blood oxygenation level dependent (BOLD) contrast was collected for each subject using a 3.0 T VHi (GE Healthcare, Milwaukee, USA) scanner. $T2^*$-weighted echo planar imaging was used for fMRI acquisition. The fMRI data processing and statistical analyses were carried out using SPM2. Results: Second-level analysis revealed significant increases in the extent of activation in the contralateral motor cortex including primary motor area (M1) after drug administration. The number of activated voxels in motor cortex was 173 without drug administration and the number increased to 1049 for high dose condition and 673 for steady-state condition respectively. However, there was no significant difference in the magnitude of BOLD signal change in terms of peak T value. Conclusion: The current results suggest that cerebral motor activity can be modulated by clopidogrel in healthy subjects and that fMRI is highly senstive to evidence such changes.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.29 no.5
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• pp.578-585
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• 1996

Cryo-grinding process comprising hammer mill-shattering and colloid mill-grinding without refrigerant was applied to sardine, pollack and squid muscle frozen at $-20^{\circ}C,\;-40^{\circ}C\;and\;-80^{\circ}C$, respectively and its characteristics were investigated. Particle size distribution of shattered product was shown larger in the order of squid, sardine and pollack and particle size of shattered product frozen at $-80^{\circ}C$ was shown smaller than those at $-40^{\circ}C$. Image of shattered product depended on freezing temperatures and fish species, suggesting particle size distribution of rheological properties can be dependent on fish species or freezing temperature. Yield of cryo- grinded product was in the range of $52.5\~62.5\%$ and Ca content of sardine or pollack product was $6\~8$ times higher than its fillet. Emulsion capacity of cryogrinded product was not decreased during processing. Therefore, this method is thought to be applicable to fish precessing, and preparation of fish paste or powaer.

• Journal of Korea Multimedia Society
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• v.15 no.9
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• pp.1075-1085
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• 2012

In clinical research using medical images, the image segmentation is one of the most important processes. Especially, the hippocampal atrophy is helpful for the clinical Alzheimer diagnosis as a specific marker of the progress of Alzheimer. In order to measure hippocampus volume exactly, segmentation of the hippocampus is essential. However, the hippocampus has some features like relatively low contrast, low signal-to-noise ratio, discreted boundary in MRI images, and these features make it difficult to segment hippocampus. To solve this problem, firstly, We selected region of interest from an experiment image, subtracted a original image from the negative image of the original image, enhanced contrast, and applied anisotropic diffusion filtering and gaussian filtering as preprocessing. Finally, We performed an image segmentation using two level set methods. Through a variety of approaches for the validation of proposed hippocampus segmentation method, We confirmed that our proposed method improved the rate and accuracy of the segmentation. Consequently, the proposed method is suitable for segmentation of the area which has similar features with the hippocampus. We believe that our method has great potential if successfully combined with other research findings.

• Journal of the Korean Institute of Intelligent Systems
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• v.24 no.2
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• pp.155-160
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• 2014

There are many image processing based algorithms and applications that fail when illumination change occurs. Therefore, the illumination change has to be detected then the illumination change occurred images need to be enhanced in order to keep the appropriate algorithm processing in a reality. In this paper, a new method for detecting illumination changes efficiently in a real time by using local region information and fuzzy logic is introduced. The effective way for detecting illumination changes in lighting area and the edge of the area was selected to analyze the mean and variance of the histogram of each area and to reflect the changing trends on previous frame's mean and variance for each area of the histogram. The ways are used as an input. The changes of mean and variance make different patterns w hen illumination change occurs. Fuzzy rules were defined based on the patterns of the input for detecting illumination changes. Proposed method was tested with different dataset through the evaluation metrics; in particular, the specificity, recall and precision showed high rates. An automatic parameter selection method was proposed for contrast limited adaptive histogram equalization method by using entropy of image through adaptive neural fuzzy inference system. The results showed that the contrast of images could be enhanced. The proposed algorithm is robust to detect global illumination change, and it is also computationally efficient in real applications.

• The Journal of Society for e-Business Studies
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• v.22 no.4
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• pp.71-101
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• 2017

Since late 2016, protectionism has been a major trend in world trade with the Great Britain exiting the European Union and the United States electing Donald Trump as the 45th president. Consequently, there has been a huge public outcry regarding the negative prospects of heavy industry firms in Korea, which are highly dependent upon international trade with Western countries including the United States. In light of such trend and concerns, we have tried to predict business performance of heavy industry firms in Korea with data regarding trade policy of the United States. United States International Trade Commission (USITC) levies countervailing duties and anti-dumping duties to firms that violate its fair-trade regulations. In this study, we have performed data analysis with past records of countervailing duties and anti-dumping duties. With results from clustering analysis, it could be concluded that trade policy trends of the Unites States significantly affects the business performance of heavy industry firms in Korea. Furthermore, we have attempted to quantify such effects by employing long short-term memory (LSTM), a popular neural networks model that is well-suited to deal with sequential data. Our major contribution is that we have succeeded in empirically validating the intuitive argument and also predicting the future trend with rigorous data mining techniques. With some improvements, our results are expected to be highly relevant to designing regulations regarding heavy industry in Korea.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.10
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• pp.2491-2499
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• 2015

Recently, the most popular technique to determine the Genotype, genetic features of individual organisms, is the GBS based on SNP from sequences determined by NGS. As analyzing the sequences by the GBS, TASSEL is the most used program to identify the genotypes. But, TASSEL has limitation that it uses only the partial sequences that is obtained by NGS. We tried to improve the efficiency in use of the sequences in order to solve the limitation. So, we constructed new data sets by quality checking, filtering the unused sequences with error rate below 0.1% and clipping the sequences considering the location of barcode and enzyme. As a result, approximately over 17% of the SNP detection efficiency was increased. In this paper, we suggest the method and the applied programs in order to detect more SNPs by using the disused sequences.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.10
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• pp.2389-2395
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• 2015

An accurate feedback about customer satisfaction is a very important factor to efficiently manage achievements in the service industry. However, Korea is lack of quantitative and standardized system of customer satisfaction measurement. This paper suggests standardized survey system with more in-depth and various methods of questionnaire survey as well as analysis which is able to efficiently evaluate customer satisfaction. This system is that investigates customer satisfaction of process based services, which uses various methods including simply designed questionnaires, customer satisfaction survey via mobile, and an investigation on follow-up satisfaction rate. In addition, we adopted scoring system to digitize a degree of satisfaction rate, so the suggested system provides an opportunity to improve specific objects those need to be improved by clearly evaluating a degree of satisfaction rate and applying various analysis techniques, such as IPA (Importance Performance Analysis), process analysis, and expectation analysis etc. This study substantiates suggested system through applying it to travel agency which is a representative enterprise of tour service.

• Progress in Medical Physics
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• v.16 no.1
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• pp.32-38
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• 2005

Impaired processing of facial information is one of the broad ranges of cognitive deficits seen in patients with schizophrenia. The purpose of this study was to elucidate the differences in brain activities involved in the process of facial working memory between schizophrenic patients and healthy comparison subjects. Ten patients with schizophrenia were recruited along with matched healthy volunteers as a comparison group. Functional magnetic resonance imaging (fMRI) was used to assess cortical activities during the performance of a 1-back working memory paradigm using images of neutral faces as mnemonic content. The patient group performed the tasks with reduced accuracy. Group analysis revealed that left fusiform gyrus, right superior frontal gyrus, bilateral middle frontal gyri/insula, left middle temporal gyrus, precuneus and vermis of cerebellum and showed decreased cortical activities in the patient group. On the other hand, an increased level of activation in lateral prefrontal cortex and parietal lobule was observed from the patient group, all in the right hemisphere. A decreased level of activity in the left fusiform gyrus among the patient group implicates inefficient processing of facial information. An increased level of activation in prefrontal and parietal neural networks from the patient group confirms earlier findings on the impaired working memory of patients with schizophrenia.

• Investigative Magnetic Resonance Imaging
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• v.11 no.1
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• pp.10-19
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• 2007

Conventional MRI methods using T1-, T2-, diffusion-, perfusion-weighting, and functional imaging rely on characterizing the physical and functional properties of the tissue. In this review, we introduce an imaging modality based on measured the mechanical properties of soft tissue, namely magnetic resonance elastography (MRE). The use of palpation to identify the stiffness of tissue remains a fundamental diagnostic tool. MRE can quantify the stiffness of the tissue thereby providing a objective means to measure the mechanical properties. To accomplish a successful clinical setting using MRE, hardware and software techniques in the area of transducer, pulse sequence, and imaging processing algorithm need to be developed. Transducer, a mechanical vibrator, is the core of MRE application to make wave propagate invivo. For this reason, considerations of the frame of human body, pressure and friction of the interface, and high magnetic field of a MRI system needs to be taken into account when designing a transducer. Given that the wave propagates through human body effectively, developing an appropriate pulse sequence is another important issue in obtaining an optimal image. In this review paper, we introduce the technical aspects needed for MRE experiments and introduce several applications of this new field.

• Journal of Korea Water Resources Association
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• v.42 no.9
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• pp.715-724
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• 2009

In case of inclined crest groyne, flow constriction with water is different. Therefore, it is proper to apply to narrow channel or there is a risk of overflow with water level rising caused by installation of groynes. This study were conducted experiments on inclined crest groyne. Main factors of inclined crest groyne are angles of crests slope and changes of water level. Velocity profile around groyne was measured by LSPIV (Large Scale Particle Image Velocimetry). Flow fields around groyne were analyzed focused on main channel and recirculation area. From the results, Thalweg change has little an effect on rate length and height of recirculation rises on increasing rate length. Length of recirculation area was about 12$\sim$16 times of rate length of groyne. Maximum velocity in main channel area was measured about 1.45$\sim$2.1 times of approach velocity and has little an effect on crest angle of groyne. Back water velocity recirculation area was decreased on approach velocity. This result presents to make stable flow to bank protection.