• The Monthly Diabetes
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• s.289
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• pp.53-56
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• 2013

당뇨병과 췌장암은 어떠한 관계가 있을까? 제2형 당뇨병의 경우 췌장암의 발생 위험은 1.8배 높다. 우리나라 췌장암 환자의 당뇨병 유병률은 28~30%로 일반인의 당뇨병 유병률이 7~9%에 비하여 3배 이상 높다(중앙암등록본부, 2012). 또한 일반인의 췌장암 유병률이 10만명 당 7명(0.007%)인데 비하여 당뇨병 환자의 췌장암 유병률은 1.6%이고, 췌장암 환자에서 당뇨병이 있을 확률은 40.6%라 한다(대한소화기학회지, 2009).

• Journal of Digestive Cancer Research
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• v.1 no.1
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• pp.43-47
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• 2013

There have been very few reports related to pancreatic cancer developing in the remnant pancreas after a resection for pancreatic cancer. We report two cases of repeated pancreatectomy for second primary pancreatic cancer. A 58-year-old man with a 2.3 cm sized low attenuated pancreatic tail mass on abdomen CT scan, received a distal pancreatectomy (adenosquamous carcinoma, stage IIB) and adjuvant chemoradiotherapy. A follow-up abdomen CT scan revealed a 2.0 cm sized pancreatic head mass in the remnant pancreas at 35 months after the distal pancreatectomy. He received a pancreaticoduodenectomy and diagnosed as ductal adenocarcinoma (stage IIA). Another 62-year-old female was declared pancreatic head mass on a regular health examination. An abdomen CT scan revealed a 3.6 cm sized mixed solid and cystic mass. She received a pylorus-preserving pancreaticoduodenectomy (ductal adenocarcinoma, stage IB) and adjuvant chemoradiation therapy. At 20 months after the resection, a 1.8 cm sized ill-defined low attenuated mass developing in the tail of remnant pancreas was detected on a follow-up abdomen CT scan. The patient received a distal pancreatectomy and diagnosed as ductal adenocarcinoma (stage IIA).

• Proceedings of the KAIS Fall Conference
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• 2009.12a
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• pp.759-763
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• 2009

본 연구의 목적은 도심지역 주민들의 건강생활습관과 췌장암과의 연관성을 파악하는데 있다. 이를 위해 2008년 6월 20일부터 7월 20일까지 종합병원에 내원한 췌장암 환자군 51명, 대조군 116명을 대상으로 설문 및 면접조사를 실시하였다. 연구결과 첫째, 음주량이 증가함에 따라 췌장암발생 위험은 유의하게 증가되었다(P<0.05). 둘째, 췌장암 발생위험에 대한 식사속도, 자극성 음식선호여부, 뜨거운 음료선호여부, 채식선호 정도 등은 환자군과 대조군간에 유의한 차이를 보이지 않았으나 교육수준이 낮을수록 수입이 낮을수록 도시보다는 농 어촌에 거주할수록 췌장암 발생위험도가 유의하게 증가함을 보였다(P<0.01). 셋째, 췌장암 발생에 대한 흡연과 음주의 상협효과 결과 흡연과 음주를 동시에 이용하였을 때 췌장암 발생위험도는 흡연 또는 음주만 이용할 때보다 상협적인 증가를 보였으며 통계적으로 유의하였다(P<0.05). 이상에서 볼 때 췌장암 진단을 위한 정기적인 검사가 보편화되지 않고 대상자의 판단에 의해서만 실시되고 있는 국내 상황을 고려할 때 본 연구에서 유의하게 나타난 위험요인들을 기초로 췌장암 위험 사정 도구의 개발이 필요하다.

• Journal of the Korean Society of Radiology
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• v.10 no.5
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• pp.299-305
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• 2016

Despite of the development of medical equipments and technology. Pancreatic cancer has maked high false positive rate and low survival rate compared to other cancers. Therefore, early catch of pancreatic cancer is the only way to enhance the viability. It is important to find the exact location of the pancreas cancer in early stage. The method of optimum scan for early detection of pancreatic cancer on PET/CT exam is proposed. Examined the anatomical region that potentially can be missing from the supine position of ordinary pet/ct exam. The characteristics and usefulness of angle variation ($0^{\circ}$, $30^{\circ}$, $45^{\circ}$, $60^{\circ}$, $90^{\circ}$) of patients scan position is analyzed. The proposed scan method (named JJ-projection) is bringing advantage of anatomical discrimination by separating stomach, liver, gallbladder duodenum and pancreas. ROC curve analysis is shows to advantage of the JJ-Projection method. The sensitivity has increased 4.6% than the supine delay scan method, the results sensitivity has increased from 91% to 95.2%. The specificity has increased from 75.1% to 84%. Compared with the results observed in cancer by biological biopsy, The accuracy has increased from 86.8% to 94.1%.

• Journal of the Korean Society of Radiology
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• v.13 no.2
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• pp.305-311
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• 2019

In this study, present the most useful delay scan time by statistical analysis of SUVm data for 30 suspected pancreatic cancer patients. Two statistical analysis and a mathematical model was applied to the theoretical formula by glucose and insulin mechanics, and a mathematical model was created. Statistical analysis was performed via Metlab p/g. Optimal delay scan time was suggested by Metlab p/g for the change of SUV value over time.In this study, for diagnosis pancreatic cancer by dual time point PET/CT, propose optimal delay scan time 131.5 minuts. The proposed delay scan time showed statistical reliability applicable to the diagnosis of pancreatic cancer (p<0.05). Delayed scanning with the suggested delay scan time of 131.5 minutes is considered to be useful for the diagnosis of pancreatic cancer compared to general PET / CT scan.hen the delayed test is performed with the proposed delay scan time 131.5 minuts, Compared with general PET/CT scans.

• The Journal of the Korea Contents Association
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• v.17 no.10
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• pp.567-575
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• 2017

In this study, when diagnosis pancreatic cancer by dual time point PET/CT, we propose SUVm 2.52 as the threshold value for performing the dual time point PET/CT exam. The hypothesis of normal distribution was adopted through data conversion of 60 pancreatic diseases. The proposed SUVm2.52 boundary value showed a significance level that could be applied to both 120 and 180 minutes of delay time scan for pancreatic cancer determination (p<0.05). C-value variation shows that delay time 2 hour test is more useful than delay time 3 hour test. When the SUVm 2.52 is set to the boundary value and the double-time point PET/CT exam is performed, the probability of distinguishing cancer from inflammation in the delayed image is 95%. When the delayed test is performed with the proposed boundary value SUVm 2.52, Compared with general PET / CT scans, it is thought that it may be helpful to distinguish pancreatic cancer.

• Journal of Digestive Cancer Research
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• v.3 no.1
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• pp.17-20
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• 2015

Pancreatic cancer is an aggressive tumor and only 10-20% patients are considered candidates for curative resection at diagnosis. While surgery remains the only chance for cure, prognosis is poor even after surgery due to high rate of recurrence. A complementary chemotherapy and radiotherapy in a multimodal approach has been attempted to improved prognosis after surgery. Since adjuvant chemotherapy has yielded an only modest outcome improvement, various neoadjuvant approaches with chemotherapy, chemoradiation, or chemotherapy followed by chemoradiation have been attempted. In this article, current knowledge of the various neoadjuvant approaches for pancreatic cancer will be reviewed and the role of the neoadjuvant strategies will be discussed.

• The Monthly Diabetes
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• s.203
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• pp.22-43
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• 2006

지난 18일 통계청이 발표한 2005년 사망원인통계결과에 의하면 2005년에 각종 암으로 사망한 사람은 총65만명으로 사망원인 중 1위를 차지했다.(전체 사망자의 26.7%), 그 다음으로는 뇌혈관 질환,심장질환,자살,당뇨병 순으로 통계 됐다. 2005년에 가장 많이 사망한 암은 폐암으로 전체 사망자의 28.4%인 13,805명이였으며, 다음으로는 위암(22.6%), 간암(22.5%), 데장암(12.5%), 췌장암(7%)의 순으로 나타났다. 사망률이 가장 많이 증가한 암은 2004년과 같이 폐암이며, 그 다음으로는 대장암,췌장암,전립선암이다. 반면 사망률이 가장 많이 감소한 암은 위암이고, 그 다음이 자궁암이다. 이렇듯 암은 한국인에게서 가장 많이 발견되는 질병 중에 하나이며, 이로 인해 많은 사람들이 사망하고 있다. 10월호에서는 과연 암이란 어떤 질병이고, 어떻게 우리의 생명을 위협하는지 알아보고자 한다.

• 건강소식
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• v.30 no.5 s.330
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• pp.16-17
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• 2006

모든 암 사망률의 30%가 흡연으로 밝혀졌다. 담배 연기가 직접 접촉하는 부위에 생기는 암인 구강암, 혀암, 식도암, 기관지암, 폐암은 흡연이 원인의 90%를 차지한다. 담배 연기가 직접 접촉하지 않는 부위에 생기는 암인 자궁경부암, 췌장암, 방광암, 신장암, 위암, 혈액암의 위험은 흡연으로 인하여 1.5~3.0배 정도 증가하게 된다.

• The Science & Technology
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• v.15 no.1 s.152
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• pp.51-53
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• 1982