• Korean Journal of Microbiology
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• v.18 no.4
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• pp.180-187
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• 1980

Cariogenic Strptococcus mutans produces a constitutive extracellular enzyme dextransucrase or glucosyltransferase that is capable of hydrolying sucrose and synthesizing the glucose polymer dextran. In this work we investigated to the dextrans produced by eight strains of Strptococcus mutans. After, 30hours the synthesized polysaccharide is 1.86mg to 4.41mg per ml on sucrose medium, and the polysaccharide is similar. Polysaccharide syntheiezd by enzyme in cell free medium is 11.4 mgto 2.36mg per ml after 10 hours.

• Proceedings of the Korea Information Processing Society Conference
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• 2020.11a
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• pp.501-504
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• 2020

본 프로젝트는 한국 의료 진로 서비스의 문제점을 개선하고자 인공지능 기반의 챗봇을 이용해 환자와 의사 간의 의사소통을 증진시키는 데 목적이 있다. Web UI 를 제공하는 Rasa X 챗봇(Chatbot) Tool 을 이용하여 메시지와 이미지를 송신할 수 있는 챗봇을 구축해냈다. 또한 YOLO model training 으로 충치 Detection 기능 등 인공지능을 접목시켜 더 효율성있는 어플리케이션(Application)을 개발했다. 이는 최근 코로나-19 로 비대면 서비스가 각광받는 가운데 챗봇 모델은 가장 경제적이고 효율적으로 실생활에 적용될 기술이다.

• Proceedings of the Korean Society of Computer Information Conference
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• 2021.07a
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• pp.359-360
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• 2021

디지털 헬스케어는 헬스케어 산업과 ICT 기술이 융합되어 개인 건강 및 질환을 관리하는 분야로서 소비자 중심의 서비스 제공을 위해 관련 산업이 크게 발전하고 있다. 최근 감염병 시대에 디지털 건강기술을 활용한 비대면 진료에 대한 요구가 급격히 증가하고 있다. 본 연구에서 제안하는 디지털 헬스케어 플랫폼은 비대면 치아 진단 및 치료 견적 플랫폼으로서 시간적·공간적 제약 없이 충치 환자에게 편리한 구강검진이 가능하게 하고, 직접 치과를 방문하지 않아도 치과 전문의에게 본인의 치아 상태를 검진받을 수 있다. 또한, 여러 치과 전문의에게 본인의 치아 치료 견적을 받고 가격을 비교하여 본인이 원하는 적절한 가격과 방법으로 치료하여 비용을 절약할 수 있도록 한다.

• Journal of dental hygiene science
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• v.3 no.1
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• pp.23-31
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• 2003

In this research, dental health awareness of 3rd graders of high schools in Icheon-city was investigated in order to use the result of this research as the basic data for school dental health program, education direction, and educational purpose. The research was done from Sep. 23. to Oct. 5 and the followings are the results of survey. (1) 85.0% of the students brush their teeth once or twice a day and more female students brush their teeth 3 times a day than male students. (2) 77% of the students had experienced dental caries and 38.0% of the students have periodontal disease, which has lower percentage than cavity. (3) Most of the students can not go to the dentists because they do not have time and 84.0% of the students have been treated in dental clinics so this tells that most of the students had experienced dental treatment. (4) 46.8% of the students had interests in dental health and male students showed more interests than female students and the difference was statistically significant(p<0.05). (5) Most of the students hear the importance and information of dental health from mass media such as TV and radio or from people around. The research shows that most of the students do not get periodic dental checkups. (6) 80.8% of the students had never taught dental health education for improvement of dental health and 76.2% of the students think that the dental health education is needed. There was no difference according to the gender. (7) Most of the students think that the dental health education is needed to prevent cavity and gingiva disease and it shows that more students tend to attend the dental health education. (8) 69.3% of the students think that brushing your teeth is important to maintain good dental health and there was no difference according to the gender. Most of the students weren't aware that periodic dental checkups, right brushing, and using fluoric toothpaste is effective for cavity protection. (9) After looking into the knowledge of the students on dental health, it shows that the knowledge is low and there is no difference according to the gender.

• The Journal of the Korea Contents Association
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• v.12 no.12
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• pp.321-328
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• 2012

The purpose of this study was to examine the toothbrushing behavior of the citizens, their use of dentifrice, awareness of the importance of dentifrice purchase and consciousness of dentifrice containing the extract of Chamaecyparis obtusa in the city of Gwangju. It's basically meant to provide some informations on the development of oral health supplies involving dentifrice containing the extract of Chamaecyparis obtusa in that city in an effort to help the city serve as a hub of the dental industry. The subjects in this study were the selected citizens in the city of Gwangju. As a result of analyzing their awareness of the importance of the considerations for the purchase and use of dentifrice, they gave 68.2% overall. They gave the highest marks of 83.3% to the importance of effect. As for the importance of each item, they gave the highest marks of 85.1% to the importance of the prevention of dental caries. Concerning differences in awareness of the importance of the external purchase factors according to age, every age group placed the most importance on inspection by the certification authorities except for those who were in their 40s and 60s, and the respondents who were in their 40s and 60s attached more importance to price than the other items. Regarding differences in awareness of the importance of effectiveness according to age, those who were under the age of 20 gave the highest marks of 79.8% to the importance of dental-caries prevention and whitening effects. As a result of asking them whether they had an intention to use dentifrice containing the extract of Chamaecyparis obtusa if this dentifrice would be developed, 54.6% replied they had the intention. When they were asked another question whether they thought this dentifrice would have an effect on oral health, 55.1% answered they thought so. 33.8% expected this dentifrice to have a primary effect on the prevention of dental caries. Given the findings of the study, full-scale R&D efforts should be directed into the development of dentifrice containing the extract of chamaecyparis obtusa in the future.

• Journal of dental hygiene science
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• v.13 no.4
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• pp.501-509
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• 2013

The purpose of the study is to confirm the effect of the oral health management program in exemplary kindergartens for prevent the dental caries. The study performs the survey on the parents about the changes in the oral health behaviors after the oral health education in April 2012 and measures the patient hygiene performance (PHP) index before the education, after the education and 3 weeks after the education to assess the removal capability to plaque on the teeth surface for the children. The analysis is performed on 130 people who join the program and respond the survey. There is no change in the behavior related to the tooth brushing of children after the oral health education. No change is found from the interest in the oral health education (p>0.05) but the recognition in the importance of the tooth positively change, as well as recognition of the tooth brushing method and the reaction to recommending to tooth brushing. The PHP index of children is significantly improved from 3.87 before the education through 2.71 after the education and 3.27 3 weeks after the education (p<0.001). The observation from the patents shows that their children have interest in preventing the cavities including 33.1% after having xylitol and 60.7% after the oral health education. In conclusion, the study confirms the effect of the oral health management program in exemplary kindergartens to prevent the cavities, meaning that it is required to activate the programs and keep implementing the programs including providing xylitol and education for teachers, parents and children to habituate the oral health behavior of the children and completely learn toothbrushing method under continuous management and reeducation.

• Journal of Life Science
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• v.15 no.5 s.72
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• pp.715-725
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• 2005

Oral streptococci are major constituents of dental plaques, and their prevalence is closely linked with various pathologic symptoms, such as dental caries. To develop natural anticaries agent, we prepared 309 kinds of plant extracts from 215 species of edible or medical plants, and antibacterial activity of the extracts against Streptococcus mutans JC-2 were evaluated based on 96 well microtiter plate assay and disk paper method, subsequently. Among the tested plant extracts, Ailanthus altissima, Paeonia lactiflora, Rubus phoenicolasius, Aralia continentalis, Quercus acutissima, Persicaria hydropiper and Agrimonia pilosa extracts showed strong antimicrobial activity. Determination of minimal inhibitory concentration (MIC) of the selected seven plant extracts showed that Ailanthus altissima, Persicaria hydropiper and Quercus acutissima extracts ($MIC=25\∼30[\mu}g/ml$) has potential as a source of natural anticaries agents.

• Korean Journal of Food Science and Technology
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• v.23 no.4
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• pp.503-509
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• 1991

Action of a cyclodextrin glycosyltransferase (CGTase) produced from alkalophilic Bacillus sp. No.4 was studied in a solution containing starch and sucrose to prepare glycosyl sucrose syrup with good sweetness and antidecaying properties of teeth. In the initial stage of the reaction the CGTase produced cyclodextrin, however, the cyclodextrin disappeared and glycosyl sucrose was formed with the lapse of reaction time. The best proportion of sucrose to starch for prodution of glycosyl sucrose was about 1 : 1. The optimum pH and temperature of the coupling reaction was pH 6.0 and $60^{\circ}C$, respectively. Main composition of glycosyl sucrose syrup prepared with 20% starch and 20% sucrose was sucrose 18%, glucosyl sucrose ($G_{2}F$) 15.3% and maltosyl sucorse ($G_{3}F$) 11.3%. And glucose, maltose and maltotriose were produced very little. Smaller amounts of acid and insoluble glucan were formed in the syrup by Streptococcus mtans OMZ176 than in the sucrose. Therefore, the prepared glycosyl sucrose sucrose syrup is expected to prevent teeth from decaying.

• Korean Journal of Food Science and Technology
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• v.39 no.3
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• pp.336-341
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• 2007

To investigate anticariogenic effects of extracts from pine needles and twigs, we measured the extracts' antimicrobial activities against Streptococcus mutans, their glucosyltransferase (GTase) inhibitory effects and their stabilities under various conditions of heat and pH. The 70% ethanol extracts of pine needles and twigs showed greater antimicrobial activities against S. mutans than the hot water extracts, and the pine twig extracts showed greater antimicrobial activity than the pine needle extracts. More specifically, the n-hexane fractions of the pine needles and twigs had the greatest effects against S. mutans, and their minimal inhibition concentration (MIC) was 0.6 mg/mL. The results of the extracts' GTase inhibitory effects indicated that the 70% ethanol extracts had greater effects than hot water extracts, and the pine twig extracts showed greater effects than the pine needle extracts. The antimicrobial activity against S. mutans for the pine needle n-hexane traction was greatly reduced as temperature increased, and was also largely affected by changes in pH. These results suggest that extracts from pine needles and twigs have anticariogenic effects and could be used as anticariogenic food additives.

• Journal of Oral Medicine and Pain
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• v.38 no.4
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• pp.299-312
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• 2013

Even though there exist a lot of study about antibacterial effects and reactions of extracted materials from plant, few study exist about oral pathogenic bacteria. Therefore we tried to recognize about the suppression effect to the periodontal pathogenic bacteria and halitosis, when add some kinds of plant extracted materials, myrrh, rhatany, chamomolilla to saliva. We used Crude drug : Myrrh tincture (100mg/ml), Ratanhia tincture (100mg/ml), Chamomile tincture(100mg/ml). We inspected about the cariogenic bateriae, S. mutans GS5 and S. sobrinus 6715, periodontal pathogenic bacteria, P. gingivalis 2561, P. intermedia ATCC 25611, Candida albicans ATCC 18804, and E. feacalis ATCC 4083, then the result follow. The plant extracted material, myrrh, rhatany, chamomomilla, which have convergence effect, bacteriocidal effect and anti-inflammation effect, show an antibacterial effect and reaction to the oral pathogenic bacteria. And with treating rhatany that have the most strong antibacterial effect, through transmission electron microscopy we could see a severe morphologic change of bacteria. This means with the plant extracted material, we can suppress the oral harmful bacteria and prevent periodontal diseases, caries, halitosis and oral inflammations. And within the future studies for the improvement of oral hygiene, our result might be a clinical evidence.