• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.12 no.2
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• pp.171-176
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• 2009

Purpose: The aim of this study was to evaluate hematologic features in Korean children with inflammatory bowel disease (IBD) in order to determine appropriate management strategies. Methods: We retrospectively analyzed the complete blood count (CBC) profiles and assessed the incidence of anemia in 25 children with IBD (Crohn disease, 16; and ulcerative colitis, 9). The correlation between hemoglobin (Hb) and duration of illness and the activity index of IBD were also investigated. Results: The incidence of anemia was 76% in IBD, 88% in Crohn disease, and 56% in ulcerative colitis. Leukocytosis and thrombocytosis were only found in Crohn disease (56% and 25%, respectively). No statistically significant correlation was observed between Hb and duration of illness in Crohn disease and ulcerative colitis or between Hb and the activity index in Crohn disease and ulcerative colitis. Conclusion: The incidence of anemia found in this study was slightly higher than in previous reports. Additionally, there was no correlation between Hb and the duration of illness or the activity index. Therefore, even if the duration of illness is short, or the activity index is low, appropriate management of children with IBD should include careful evaluation for anemia.

• International Commerce and Information Review
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• v.16 no.2
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• pp.157-183
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• 2014

The aim of this study is to establish a detailed strategic countermeasure for Korean west coast ports(Pyeongtaek Dangjin Port, Incheon Port, and Gwangyang Port) to be developed into core ports in the Pan-Yellow Sea area as the results such as strategic partnership ports analysis through the container volume analysis in Korean ports are comprehensively taken into account between west coast ports and other major ports in the Pan-Yellow Sea area. This study utilized related data which import and export data by Office of Customs Administration and SPIDC by Ministry of Maritime Affairs and Fisheries for analyzing container volume between two ports. Strategic partnership ports were selected based on in-depth analysis on 5 standards such as container volume in 2012, increase rate of trading, occupancy rate, variance rate, and contribution of container volume. As a result of selection strategic partnership port in Pan-Yellow Sea area, Lianyungang, Tianjin, Yantai, Qingdao, Dalian port in Pyeongtaek Dangjin Port, Shidao, Weihai, Qingdao, Tianjin, Dalian port in Incheon, Qingdao, Yantai, Dalian, Lianyungang port in Gwangyang port. Also this study proposed implications of countermeasure to establish strategic partnership ports for each of west coast ports.

• The Southeast Asian review
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• v.28 no.1
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• pp.145-171
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• 2018

Laos' 2017 is a year of political "stagnation" and economic "change". In the political arena, despite the achievements such as the improvement of the corruption perception index (CPI), it is necessary to watch the progress of the reform. Diplomatically, the influence of China is expected to increase further. In particular, since November 2017, Xi Jinping's visit to Laos is expected to strengthen the framework of cooperation between the economic corridor and Lanchang-Mekong Cooperation Meeting. And Laos continued to have friendly relations with other neighboring countries, the ASEAN countries. However, the issue of the Laos-Cambodian border issue following the general election in Cambodia may recur. The economic sector maintained a high growth rate due to capital inflows from the construction of large infrastructures and the favorable tourism industry, but structural problems such as deficits in the fiscal and current account should be resolved. Korea and Laos discussed the comprehensive cooperation between the two countries through the Mekong Senior Officials' Meeting in March 2017 and the Ministerial Meeting of the Korean-Lao Foreign Minister in September 2017. Laos is Korea's eighth ODA aid (grant), and ODA will become an important diplomatic cooperation channel between the two countries in the future. In the economic relationship, the trade sector is on a declining trend, but investment and human exchanges are steadily increasing.

• Journal of Korea Entertainment Industry Association
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• v.15 no.4
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• pp.383-390
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• 2021

Recently, the drone industry is rapidly expanding as it is suggested that it will be used in various fields. As the size of the drone market grows, interest in drone-related certificates is also increasing. However, the current drone-related qualification system and education system are insufficient. Thus this study, analyzed the necessity of drone training, the features of functional games, and the effectiveness of educational training using AR through related technical studies to solve the practical difficulties of drone educational training. Later, drone educational training game contents using AR were divided into practice mode and test mode based on the drone national qualification course practical test, and the result screen was displayed at the end of the curriculum so that players could learn by level and evaluate the results on their own. In addition, constructed a hybrid processing system and network and AR operation system for response rate and response speed, implemented drone training game contents utilizing AR based on the design contents. It is expected that the use of game content using AR presented in this paper for drone training will further alleviate environmental difficulties and improve the sense of immersion in play, which will lead to a more effective drone educational training experience.

• Journal of the Korea Convergence Society
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• v.12 no.11
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• pp.53-67
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• 2021

According to statistics, the number of mobile payment users in China shows an increasing trend year by year. However, less than half of people over 60 years old use mobile payment. The purpose of this study is to explore the reasons for the low usage rate of mobile payment platforms among the elderly in China. Through literature research, questionnaires and interviews, the author found that the main obstacle for the elderly in China to use mobile payment platforms is acceptance barrier. Then, the user experience research method and technology acceptance model (TAM) were combined to construct a new research model and five hypotheses affecting acceptance behavior in the model were summarized. Finally, the Analysis of Covariance(ANCOVA) was used to test the hypotheses and found that satisfaction (SA), perceived usefulness (PU) and job relevance (JR) had significant coefficients of 0.001, 0.000 and 0.004 respectively, all of which were less than 0.05 and therefore had a significant effect on acceptability. The other two elements, perceived ease of use (PE) and self-efficacy (SE), did not have a significant effect on acceptability. Ultimately, a new user experience acceptability model was constructed to provide theoretical support for mobile payment platform developers and designers to develop products from the acceptability perspective, so as to develop more mobile payment methods suitable for elderly users and improve the acceptance of mobile payment by the elderly.

• Journal of the Korea Institute of Building Construction
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• v.22 no.4
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• pp.391-402
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• 2022

With the number of social overhead capital(SOC) projects that introduce private capital on the rise, overseas construction global companies today need to establish and advance their overseas order strategies. In this context, the purpose of this study is to develop the public private partnership(PPP) capacity evaluation model for developing countries and use it for domestic overseas construction companies to establish strategies for overseas expansion. The PPP competency evaluation model analyzes the importance of PPP competency evaluation items and infrastructure environment competency evaluation items through a review of previous studies and an interview survey with overseas construction experts. Through the above analysis results and expert surveys, problems that may occur when overseas construction companies enter the PPP market were derived, and improvement measures were proposed. Countries with a high probability of overseas construction companies entering the PPP market were determined to be those that have a mature PPP system, low risk in construction, and a good entry environment with a high infrastructure market size and growth rate. In addition, a lack of PPP investment experience, the absence of information on the infrastructure environment, and a shortage of PPP experts were identified as problems when entering the overseas construction PPP market. As an improvement measure, it was suggested to enter in cooperation with domestic and foreign companies. In addition, a plan was proposed to develop a curriculum to secure experts in areas such as PPP finance and contracts and to provide PPP information for each country. These findings are expected to contribute to overseas construction companies proposing strategies for entering the overseas construction market and using them for overseas expansion strategies and policy establishment.

• Proceedings of the Korea Water Resources Association Conference
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• 2021.06a
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• pp.62-62
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• 2021

산업 고도화로 인하여 복잡하고 다양한 유기물의 사용량이 증가하였으며, 공공수역 내 새로운 오염물질이 유입됨에 따라 생화학적 산소요구량(BOD) 중심의 수질평가에 한계를 나타내었다. 이후 난분해성 물질을 고려한 유기물관리 정책과 총량관리의 필요성이 제기되었고 국내 하천과 호소에서는 총 유기탄소(TOC)를 유기물 관리지표로 설정하였다. 그러나 부영양 하천과 호소에서 TOC는 외부 부하뿐만아니라 식물플랑크톤의 과잉성장에 의해 증가할 수 있는 항목이므로 TOC 관리정책 추진을 위해서는 유기물의 기원에 대한 파악이 필요하다. 특히, 국내 하천에서 나타나고 있는 난분해성 유기물 오염도의 증가 추세에 대응한 실효성 있는 유기물 오염관리 정책을 수립하기 위해서는 다양한 유기물의 근원을 정확하게 파악하는 것이 매우 중요하다. 본 연구의 목적은 금강 수계 최대 상수원인 대청호를 대상으로 3차원 수리-수질 모델을 적용하여 유기탄소 성분 별 유입과 유출, 내부생성 및 소멸량을 평가하고 저수지시스템에서의 유기탄소 물질수지를 해석하는 데 있다. 유기탄소 물질수지 해석을 위해 AEM3D 모델을 사용하였으며 2017년을 대상으로 입력자료를 구축한 후 보정을 수행하였고 2018년을 대상으로 모델을 검정하였다. 모델은 유기탄소를 입자성, 용존성, 그리고 난분해성과 생분해성으로 구분하여 모의하며 유기물질 성상별 실험결과를 이용하여 입력자료를 구축하였다. 유기탄소 물질수지 해석을 위해 4가지의 탄소성분과 조류 세포 내 탄소의 질량 변화율을 계산하였다. 이를 위해 외부 유입·유출부하율, 수체 내 생성(일차생산, 재부상, 퇴적물과 수체 간 확산) 및 소멸률(POC 및 조류 침강, DOC 무기화, 탈질)을 고려하였다. 모델은 2017년과 2018년의 물수지를 적절히 재현하였으며 저수지의 성층구조를 잘 재현해내면서 전반적인 수온, 수질을 적절하게 모의하였다. 연간 TOC 부하량 중 내부기원 부하량은 2017년 68.4 %, 2018년은 높은 강우량의 영향으로 55.0%로 산정되었다. 내부 소멸 기작 중 침전으로 인한 손실이 가장 높은 것으로 나타났으며, 2017년과 2018년 각각 31.3%, 29.0%로 나타났다. TOC의 공간분포는 Chl-a 농도 분포와 유사하게 나타났으며, 댐 설치로 형성된 정체수역은 유역의 유기물 순환에 많은 영향을 미치는 것으로 평가되었다. TOC 관리 정책 기초자료 확보를 위해서는 향후 유역-저수지 시스템을 연계한 유기물 물질순환 심층 연구가 필요하다.

• The Korean Journal of Franchise Management
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• v.3 no.2
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• pp.39-54
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• 2012

Franchise system in Korea has been developed in different way compared with American way of franchising based on mutual contract and intellectual property context. Korean franchising is mostly based on product distribution franchise concept rather than business format franchise in which franchisor makes revenue sources from providing their products as much as possible thru group purchasing and logistics rather than receiving royalty. Many franchise enterprises from Korea drive to enter into global franchise market based on the successful performance of Korean way of franchising. Korean enterprises are required to prepare completely for research and survey regarding local culture, custom, way of life and legal matters etc. when entering into global franchise market to gain a substantial performance. CaffeBene recently entered into American franchise business with success, and many other Korean franchise enterprises have a deep interest in proceeding with global franchise business modeling CaffeBene case. There is no Korean franchise enterprise in United Kingdom in which service franchise area in particular with personal service is considered to become a promising and potential franchise business and many people show a great interest in Oriental foods and beverages with well-being trend. Korean franchise enterprises have now access to United Kingdom easier because IT industry including internet of the country have been developed by leaps and bounds since London Olympic in 2012. The purpose of this study is to suggest key success factors and basic strategy such as situation analysis, selecting business format, and marketing strategy for successful launching of franchise business in United Kingdom.

• Tuberculosis and Respiratory Diseases
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• v.45 no.5
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• pp.962-974
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• 1998

Background: Alteration of p53 tumor suppressor genes is most frequently identified in human neoplasms, including lung carcinoma. It is well known that bcl-2 oncoprotein protects cells from apoptosis. Recent studies have demonstrated that bcl-2 expression is associated with favorable prognosis for patients with non-small cell lung carcinoma. However, the precise biologic role of bcl-2 in the development of these tumors is still obscure. p53 and bcl-2 have important regulatory influence in the apoptotic pathway and thus their relationship is of interest in tumorigenesis, especially lung cancer. Purpose: The author investigated to know the prognostic significance of the expression of p53 and bcl-2 in radically resected non-small cell lung cancer. Method: 84 cases of formalin-fixed paraffin-embedded blocks from resected primary non-small cell lung cancer from 1980 to 1994 at Hanyang University Hospital were available for both clinical follow-up and immunohistochemical staining using monoclonal antibodies for p53 and bcl-2. Results : The histologic classification of the tumor was based on WHO criteria., and the specimens included 45 squamous cell carcinomas(53.6%), 28 adeonocarcinomas(33.3%) and 11 large cell carcinomas(13.1 %). p53 immunoreactivity was noted in 47 cases of 84 cases(56.0%). bcl-2 immunoreactivity was noted in 15 cases of 84 cases(17.9%). The mean survival duration was $64.23{\pm}10.73$ months in bcl-2 positive group and $35.28{\pm}4$. 39 months in bcl-2 negative group. The bcl-2 expression was significantly correlated with survival in radically resected non-small cell lung cancer patients(p=0.03). The mean survival duration was $34.71{\pm}6.12$ months in p53 positive group and $45.35{\pm}6.30$ months in p53 negative group(p=0.21). The p53 expression was not predictive for survival. There was no correlation between combination of the different status of p53 and bcl-2 expression in our study. Conclusions : The interaction and the regulation of new biologic markers, such as those involved in the apoptotic pathway, are complex. bcl-2 overexpression is a good prognostic factor in non-small cell lung cancer and p53 expression is not significantly associated with the prognostic factor in non-small cell lung cancer.

• Food Science and Industry
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• v.53 no.1
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• pp.2-32
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• 2020

In recent years, significant importance has been given to chitooligosaccharides (COS) due to its potent notable biological applications. COS can be derived from chitosan which is commonly produced by partially hydrolyzed products from crustacean shells. In order to produce COS, there are several approaches including chemical and enzymatic methods which are the two most common choices. In this regard, several new methods were intended to be promoted which use the enzymatic hydrolysis with a lower cost and desired properties. Hence, the dual reactor system has gained more attention than other newly developed technologies. Enzymatic hydrolysis derived COS possesses important biological activities such as anticancer, antioxidant, anti-hypersentive, anti-dementia (Altzheimer's disease), anti-diabeties, anti-allergy, anti-inflammatory, etc. Results strongly suggest that properties of COS can be potential materials for nutraceutical, pharmaceutical, and cosmeceutical product development.