• Journal of the Korean Society of Radiology
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• v.17 no.5
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• pp.717-723
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• 2023

Liver disease is highly associated with death, and other abdominal diseases are also important causes affecting a person's lifespan, and a CT scan is essential when treating abdominal diseases. High radiation exposure is essential to create images that are good for reading, but managing the patient's radiation exposure is also essential. In this study, a post-processing wavelet algorithm was proposed to improve the image quality of abdominal CT images. Wavelets have the disadvantage of having to set a threshold value depending on the type of input image. Therefore, we experimentally proposed the threshold value of the wavelet and evaluated whether the image quality was effective. As a result of the experiment, the optimal threshold value for abdominal CT images was calculated to be 50. In the case of image 1, noise was improved by 49% and in the case of image 2, by 29%, and the contrast also increased. if the results of this study are applied for post-processing after abdominal CT, image quality can be improved and it will be helpful in disease diagnosis.

• Proceedings of the KOSOMBE Conference
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• v.1995 no.11
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• pp.154-156
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• 1995

• Progress in Medical Physics
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• v.21 no.2
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• pp.209-217
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• 2010

Retinal prostheses are being developed to restore vision for the blind with retinal diseases such as retinitis pigmentosa (RP) or age-related macular degeneration (AMD). Since retinal prostheses depend upon electrical stimulation to control neural activity, optimal stimulation parameters for successful encoding of visual information are one of the most important requirements to enable visual perception. Therefore, in this paper, we focused on retinal ganglion cell (RGC) responses to different voltage stimulation parameters and compared threshold charge densities in normal and rd1 mice. For this purpose, we used in vitro preparation for the retina of normal and rd1 mice on micro-electrode arrays. When the neural network of rd1 mouse retinas is stimulated with voltage-controlled pulses, RGCs in degenerated retina also respond to voltage amplitude or voltage duration modulation as well in wild-type RGCs. But the temporal pattern of RGCs response is very different; in wild-type RGCs, single peak within 100 ms appears while in RGCs in degenerated retina multiple peaks (~4 peaks) with ~10 Hz rhythm within 400 ms appear. The thresholds for electrical activation of RGCs are overall more elevated in rd1 mouse retinas compared to wild-type mouse retinas: The thresholds for activation of RGCs in rd1 mouse retinas were on average two times higher ($70.50{\sim}99.87\;{\mu}C/cm^2$ vs. $37.23{\sim}61.65\;{\mu}C/cm^2$) in the experiment of voltage amplitude modulation and five times higher ($120.5{\sim}170.6\;{\mu}C/cm^2$ vs. $22.69{\sim}37.57\;{\mu}C/cm^2$) in the experiment of voltage duration modulation than those in wild-type mouse retinas. This is compatible with the findings from human studies that the currents required for evoking visual percepts in RP patients is much higher than those needed in healthy individuals. These results will be used as a guideline for optimal stimulation parameters for upcoming Korean-type retinal prosthesis.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.36 no.3
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• pp.195-201
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• 2000

This paper discusses methods for the stable bottom detection and the optimum bottom offset which enable to separate the fish echoes from the bottom echoes with echo integration of demersal fish. In preprocessing of the echo signal, the bottom detection has to be done stably against the fluctuation of echo level and the bottom offset has to be set to a minimum height such that near bottom fish echoes are included Two methods of bottom detection, namely echo level threshold method and maximum echo slope method were compared and analyzed. The echo level method works well if the ideal threshold level was given but it sometimes misses the bottom because of the fluctuation of the echo. Another method to detect the bottom which uses maximum echo slope indicates the simple and stable bottom detection. In addition, the bottom offset has to be set near to the bottom but not to include the bottom echo. Optimum bottom offset should be set a few samples before the detected bottom echo which relates the beginning of pulse shape and acoustic beam pattern to the bottom feature.

• Proceedings of the Acoustical Society of Korea Conference
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• spring
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• pp.367-372
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• 2004

디지탈 보청기의 DSP 칩 파라미터들은 보청기 사용자에게 가장 최적의 파라미터들로 구성되어져야 한다. Gennum GB3211과 같은 디지탈 보청기용 DSP 칩은 전용 전자 칩으로써 약 90 여개의 제한된 파라미터들을 조합하여 약 47억여개 이상의 거의 무한한 정도의 다양한 경우 수를 대응하도록 제작되었다. 보청기 사용자의 전기-음향 효과를 극대화하기 위해 가장 최적화된 파라미터 피팅 프로그램을 개발하였다. 컴퓨터 입력이 가능한 오디오그램 청력 역치로부터 여러 다른 Formula를 사용할 뿐 만 아니라, 마이크로폰과 리시버의 보정 효과를 모두 포함하는 최적 보청기 피팅 프로그램을 개발하였으며 몇 가지 사례를 적용해 보였다.

• Journal of Food Hygiene and Safety
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• v.14 no.4
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• pp.319-326
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• 1999

Recently, it is continuously rising to concern about the health risk being induced by microorganisms in food such as Escherichia coli O157:H7 and Listeria monocytogenes. Various organizations and regulatory agencies including U.S.FPA, U.S.DA and FAO/WHO are preparing the methodology building to apply microbial quantitative risk assessment to risk-based food safety program. Microbial risks are primarily the result of single exposure and its health impacts are immediate and serious. Therefore, the methodology of risk assessment differs from that of chemical risk assessment. Microbial quantitative risk assessment consists of tow steps; hazard identification, exposure assessment, dose-response assessment and risk characterization. Hazard identification is accomplished by observing and defining the types of adverse health effects in humans associated with exposure to foodborne agents. Epidemiological evidence which links the various disease with the particular exposure route is an important component of this identification. Exposure assessment includes the quantification of microbial exposure regarding the dynamics of microbial growth in food processing, transport, packaging and specific time-temperature conditions at various points from animal production to consumption. Dose-response assessment is the process characterizing dose-response correlation between microbial exposure and disease incidence. Unlike chemical carcinogens, the dose-response assessment for microbial pathogens has not focused on animal models for extrapolation to humans. Risk characterization links the exposure assessment and dose-response assessment and involve uncertainty analysis. The methodology of microbial dose-response assessment is classified as nonthreshold and thresh-old approach. The nonthreshold model have assumption that one organism is capable of producing an infection if it arrives at an appropriate site and organism have independence. Recently, the Exponential, Beta-poission, Gompertz, and Gamma-weibull models are using as nonthreshold model. The Log-normal and Log-logistic models are using as threshold model. The threshold has the assumption that a toxicant is produce by interaction of organisms. In this study, it was reviewed detailed process including risk value using model parameter and microbial exposure dose. Also this study suggested model application methodology in field of exposure assessment using assumed food microbial data(NaCl, water activity, temperature, pH, etc.) and the commercially used Food MicroModel. We recognized that human volunteer data to the healthy man are preferred rather than epidemiological data fur obtaining exact dose-response data. But, the foreign agencies are studying the characterization of correlation between human and animal. For the comparison of differences to the population sensitivity: it must be executed domestic study such as the establishment of dose-response data to the Korean volunteer by each microbial and microbial exposure assessment in food.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.39 no.11
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• pp.897-903
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• 2015

In this paper, the contrast therapy of skin was numerically investigated by solving the conjugate heat transfer problem. A finite volume method based on the SIMPLE algorithm was adopted to solve the axisymmetric incompressible Navier-Stokes equations, coupled with an energy equation. These equations are strongly coupled with the Pennes bio-heat equation in order to consider the effect of blood perfusion rate. We investigated the thermal response of skin at some selected depths for various input temperature profiles of a stimulator for contrast therapy. From the numerical simulations, the regions with cold/hot threshold temperatures were found for five input temperature profiles. It was shown that the temperature varies mildly for different input profiles as the depth increases, owing to the Pennes effect. The input temperatures for effective hot/cold stimulation of dermis layer were found to be $47^{\circ}C$ and $7^{\circ}C$, respectively. The present numerical results will be used for finding an optimal temperature profile of a stimulator for contrast therapy.

• Journal of Nutrition and Health
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• v.27 no.2
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• pp.181-191
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• 1994

This study was designed to evaluate anthropometric measurement, blood pressure, salt threshold and salt preference of children living at orphan home in Seoul and Kangnung. Anthropometric data of the subjects were slightly lower than the Korean standards, and those of children in Seoul were slightly higher than those of children in Kangnung. There were no differences in salt threshold and salt preference between Seoul and Kangnung. Blood pressure had positive correlation that partialled out of age with various anthropometric measurements(body weight, mid-arm circumference, girth of chest, BMI and body surface area), but did not correlated to salt threshold and salt preference.

• Progress in Medical Physics
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• v.16 no.4
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• pp.183-191
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• 2005

The utilization of PET has been increased so fast since the usefulness of the PET has been proved in various clinical and research fields. Among the many applications, the PET Is especially useful in oncology and most of the clinical PET scans are peformed for the oncologic examination Including the different diagnosis of malignant and benign tumors and assessment of the treatment effects and recurrent tumors. As the PET-CT scanners are widely available, there is Increasing interest in the application of the PET Images to the radiation treatment planning. Although the CT images are conventionally used for the target volume determination in the radiation treatment planning, there are fundamental limitation In use of only the anatomical information. Therefore, the volume determination of the functionally active tumor region using the PET would be important for the treatment planning. However, the accurate determination of the tumor boundary is not simple in PET due to the relatively low spatial resolution of the currently available PET scanners. In this study, computer simulations were peformed to study the relationship between the lesion size, PET resolution, lesion to background ratio and the threshold of Image Intensity to determine the true tumor volume.

• Journal of Preventive Medicine and Public Health
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• v.29 no.3 s.54
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• pp.539-553
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• 1996

The study was conducted from May to September in 1994 to investigate applicability of the Hearing Handicap Inventory for the Elderly-Screening version(HHIE-S) in parallel with the pure-tone audiometer to the initial screening test of noise-induced hearing loss(NIHL) in some noise-exposed workers. Subjects were selected by systemic sampling that took every 10th person from 6, 700 workers taking the annual occupational health examination by the department of Health Maintenance of Dongsan Hospital Keimyung University in Taegu. The authors administered the pure-tone audiometric test and self-reported questionnaire of HHIE-S including items of sociodemographic and job-related variables concurrently. The final subjects analysed were 1,019(488 males and 531 females) excluding fourteen persons who had many missing values in their questionnaires. The reliability coefficients of HHIE-S scale by Cronbach's alpha were 0.84. In the univariate analysis of hearing handicap measured by the HHIE-S, work duration, military service and the hearing threshold loss at 1KHz and 4KHz by the initial audiometer were significant in males while age, work duration and hearing threshold loss at 1KHz and 4KHz were significant in females. In the stepwise linear regression analysis, hearing threshold loss at 1KHz and 4KHz, was the only selected variable explaining the hearing handicap in males and hearing threshold loss at 1KHz and 4KHz, age, and work duration were selected in females. In ROC curves for HHIE-S scores against NIHL as gold standard which was defined by the follow-up audiogram as more than 30dB of the average of 0.5/1/2KHz and 50dB at 4KHz, the optimal cutoff for the parallel HHIE-S appeared to be 8. The results suggest that HHIE-S appeared to have some reliability and validity in this data and might be used in screening NIHL in parallel with pure-tone audiometer in noise-exposed workers.