• Title/Summary/Keyword: 초기상성도

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Strength and Initial Stiffness of Composite Beams with an Egg-Shaped Web-Opening (달걀형 웨브 개구부를 가진 합성보의 강도와 초기강성도)

  • 김원기;박노웅
    • Journal of the Earthquake Engineering Society of Korea
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    • v.4 no.4
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    • pp.27-35
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    • 2000
  • 강한 지진 하에서 효율적으로 거동하도록 유도하는 연구중의 하나로서 개구부를 가진 합성보의 이력거동을 조사하고 있다. 직사각형 개구부를 가진 합성보에 대한 연구를 발전시켜 에너지 소산능력이 보다 큰 달걀형 개구부를 가진 합성보에 대한 연구를 수행하였다. 실험적 연구와 비선형 FEM 해석 연구 모두가 그러한 합성보의 연성도를 입증하였다. 본 연구는 달걀형 개구부를 가진 합성보의 강도와 초기강성도를 산정하는 약산식을 제시하였고, 그 결과를 실험 및 비선형 FEM 해석의 결과와 비교 분석하였다.

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Antitumor metabolites of micro-organisms (미생물의 항종상성 대사산물)

  • 김병각
    • YAKHAK HOEJI
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    • v.17 no.2
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    • pp.71-91
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    • 1973
  • 미생물의 대사산물은 극히 다양함으로 그중에는 암세포에 선택적으로 작용하여 증식을 억제하는 것이 있으리라는 예상하에서 종양을 이식한 동물을 사용하여 항암성 물질을 스크리-닝하기 시작한 것은 1951년경 부터였다. 그리하여 지난 20여년간에 200종 이상의 항종양성 물질이 보고되었고 그 화학구조는 가지 각색이다. 그간의 연구의 추세를 들이켜 본다면 초기에는 항종양작용에 중점을 두었기 때문에 독성이 강한 물질이 다소 보고되었으며 중기에는 조직배양을 이용했기 때문에 세포독 물질이 주축을 이루고 있다. 근래에는 독성이 낮은 물질, 특히, 고분자의 물질이 추구되고 있는 경향이다. 이미 보고된 200여종의 항종양성 항생물질중 실지로 쓰이고 있는 것은 10여종에 불과하다는 사실은 전신요법제로써의 항암제의 독어이 얼마나 중요한 가를 잘 증언해 주고 있다. 항종양성 항생물질은 화학구조, 생성하는 미생물, 작용기전 등에 분류할 수 있다. 그러나 화학구조가 다양하다는 점에서 또 생성하는 미생물은 대개 방성균류이라는 점에서 그리고 작용기전은 대개 핵산에 작용한다는 점에서 볼때 이러한 분류기준을 채택한다는 것이 특별히 유리한 점이 없는 것 같으므로 여기서는 편의상 발견된 연대순으로 나열하여 기재하기로 한다.

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The Usefulness of the Admission Base Deficit as a Marker of Mortality in Severely Injured Patients with Blunt Trauma (둔상성 중증 외상환자에서 내원 초기에 시행한 동맥혈 염기결핍과 예후의 관계)

  • Yu, Byung-Chul;Chung, Min;Lee, Gil-Jae;Lee, Jung-Nam
    • Journal of Trauma and Injury
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    • v.26 no.1
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    • pp.1-5
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    • 2013
  • Purpose: The base deficit (BD) at admission in severely injured patients has been shown to predict the adequacy of resuscitation and outcome, but this relationship is not well established in the Korean experience. The purpose of this study was to define the association between arterial blood gas (ABG) values and the mortality for patients with severe blunt trauma at a developing trauma center in Korea. Methods: A retrospective review of 415 adult patients with severe blunt trauma was conducted using electronic medical records from Jan. 2010 to Dec. 2011. Results: A total of 256 patients had ABG drawn within 1 hour of arrival. Patients who expired displayed a higher lactate level (4.86 vs. 3.31, p<0.0001), a worse BD (-7.99 vs. -5.37, p=0.001), and a lower pH (7.31 vs. 7.34, p=0.011) at arrival compared with those who survived. A statistically significant association was also observed between BD and blood product usage (p=0.001). Conclusion: The base deficit at admission is a useful marker of mortality and outcome in severely injured patients with blunt trauma in Korea.

Improvement in Storabilities of Rice Bran Protein Film Containing Bacteriocin Produced by Pseudomonas putida 21025 (Pseudomonas putida 21025가 생성하는 bacteriocin을 이용한 항균성 미강 단백질 필름의 저장성 향상)

  • 김은정;김경미;배동호
    • Food Science and Preservation
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    • v.10 no.3
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    • pp.411-416
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    • 2003
  • An effort was attempted to utilize an under-utilized protein source, rice bran protein, in coating or wrapping food material for the purpose of protection them from oxidation and bacterial infection. However, the utilization of rice bran protein as a food coating material is limited because the rice bran protein coating material itself can be spoiled by a bacterial infection. Therefore, this study was conducted to produce the economical and antibacterial rice bran protein film by utilizing rice bran and bacteriocin-producing microorganism. Bacteriocin produced by Pseudomonas putida 21025 was partially purified after 33h of shaking incubation at 30$^{\circ}C$. The amount of amino-type nitrogen did not increase in the rice bran protein film containing the bacteriocin any more after gradual increase upto the content of 0.22% for 8 days, while that without the bacteriocin increased continuously, implying that application of the bacteriocin to the rice bran had positive effects on prolonging the shelf-life of not only film itself but also the foods wrapped by this film.

Shock Thyroid in a Patient with Septic Shock: A Case Report and Literature Review (패혈성 쇼크 환자에서 동반된 쇼크 갑상샘: 증례 보고 및 문헌 고찰)

  • Wang Hyon Kim;Min Seon Kim;Jun Ho Kim;Kyung Hee Lee;Jung Hwan Lee
    • Journal of the Korean Society of Radiology
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    • v.82 no.5
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    • pp.1328-1333
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    • 2021
  • Shock thyroid is a rare manifestation of the CT hypotension complex and can be diagnosed when thyroid and perithyroidal edemas are observed on CT during the onset of shock. Shock thyroid can be a useful CT sign for decompensated shock. This condition is reversible and recovers rapidly with adequate treatment. We present the case of an 84-year-old female with septic shock, exhibiting CT features consistent with a shock thyroid. We also reviewed the clinical and radiological findings reported in the literature. The present case emphasizes that shock thyroid can be an early indicator of impending hemodynamic instability and has important prognostic and therapeutic implications.

Treatment of Traumatic DislocationofMetacarpophalangeal Joint of the Thumb (무지 중수지 관절의 외상성 탈구 치료)

  • Rhee Seung-Koo;Song Seok-Whan;Lee Hwa-Sung;Chung Jin-Wha;Chung Do-Hyun;Lee Won-Hee
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.1 no.2
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    • pp.143-148
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    • 2002
  • Purpose: We examined patients to evaluate the clinical results of traumatic metacarpophalangeal(M-P) dislocations of the thumb, uncommon and irreducible. Materials and Methods: In 11 traumatic M-P dislocations of the thumb, the types of dislocations were 10 dorsal and 1 volar dislocations resulted from the impacted and hyperextended forces on thumb. Authors evaluated the possibility of closed reduction, the anatomical structures interfering with closed reduction, and the surgical approaches. Results: Eight cases were treated with open reduction through volar approach and two cases were treated with closed reduction. Joint fusion was done with a plate in a chronic case. Initial closed reduction was attempted in all cases, but succeeded in only 2 cases because the interposed ruptured volar plate, the flexor pollicis brevis tendon and ulnar sesamoid bone at the volar side of the M-Pjoint were the obstacles to reduce. The metacarpal head was caught in button-hole slit between theflexor pollicis brevis and the ruptured volar joint capsule in all cases. Conclusion: Similar with the M-P joint dislocations of other fingers, the dorsal complex M-P dislocations of the thumb due to hyper extension are unusual and can't easily be reduced by closed manipulation. It is necessary to pay attention to the ruptured volar plate, capsule, the subluxated portion ofthe sesamoid and flexor pollicis brevis as interfering structures.

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Properties of Engineering and Durability Concrete with Fly-ash and Blast Furnace Slag in Normal Strength Level (플라이애시 및 고로슬래그 첨가율에 따른 일반강도영역 콘크리트의 공학적 특성 및 내구성)

  • Kim, Gyu-Yong;Shin, Kyoung-Su;Lim, Chang-Hyuk;Nam, Jeong-Soo;Kim, Moo-Han
    • Journal of the Korean Recycled Construction Resources Institute
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    • v.5 no.1
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    • pp.103-110
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    • 2010
  • Recently, reducing usage of cement and using by-product of industry such as blast furnace slag and fly-ash have been increased to reduce $CO_2$ gas emission. That apply to construction. As a result, reduction of environmental stress and recycling of resources are expected. In this study, as basic study to the reuse of resources and reduce Environmental Load, comparing and analyzing hardening characteristics and durability as using the blast furnace slag and fly-ash, examining concrete characteristics substituted the three elements for the blast furnace slag and fly-ash and evaluating the relationship as binder. Through this, it want to provide the basic data for mass utilization. Blast furnace slag powder and replaced at fly-ash compressive strength of concrete in the strength of the initial seven days material age lower level of expression significantly compared to the concrete, but, 28 days after the similar or higher compressive strength than the concrete expression of the was. In addition, the reserves replacement of blast furnace slag powder salt injury increasing resistance are seen improvements, according to the conventional blast furnace slag powder study by the chloride ions on the surface of the concrete are improved being fixation salt injury resistance is considered.

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Effects of Taeumin, Soeumin and Soyangin Prescriptions on the Adipocyte Induced by Gold Thioglucose in the Rat (태(太)·소음인(少陰人), 소양인(少陽人)의 처방(處方)이 Gold thioglucose로 유발(誘發)된 백서(白鼠)의 비만병(肥滿病)에 미치는 효과(效果))

  • Kim, Kyung-Yo
    • Journal of Sasang Constitutional Medicine
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    • v.8 no.1
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    • pp.295-317
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    • 1996
  • It is researched to elucidate the effects of Taeumjowuitang(TE,太陰調胃湯), Sibimikwanjungtang(SE, 十二味寬中湯) and Yangkeogsanwhatang(SY,凉膈散火湯) on the obesity induced by gold thioglucose and the differentiation and growth of preadipocyte 3T3-L1 in the mouse. The result were as follows: 1. TE,SE and SY extracts improved the blood level of transaminase in the obese mouse induced by gold thioglucose. 2. TE,SE and SY extracts inhibited the increase of liver fat and body fat in the obese mouse induced by gold thioglucose. 3. TE,SE and SY extracts inhibited the increase of body weight in the obese mouse induced by gold thioglucose. 4. TE,SE and SY extracts inhibited the growth of undifferentiate preadipocyte 3T3-L1. 5. TE,SE and SY extracts showed inhibitory effect on the differentiation of preadipocyte 3T3-L1. The above results suggest that the TE,SE and SY extracts may be used on the obesity induced by the overgrowth and differentiation of adipocyte, and the accumulation of fat in liver and body.

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