• The Korean Journal of Pharmacology
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• v.30 no.1
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• pp.59-65
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• 1994

The experiments were performed to determine whether lidocaine interferes with the utilization of lipid as source of energy fuel for the contractile process by the isolated rat atria. Rats were starved for two days in order to inerease the lipid content of the heart. Atria from starved rats were better able to maintain their contractility in the absence of exgenous substrate, and also were more resistant to depression by lidocaine than atria from fed rats. Starvation results in a marked loss of body weight in rats. In contrast to the starved rats, the body weight of fed rats inereased with time. The smaller reduction in contractile activity of atria from the starved rats may suggest that endogenous lipid accumulates during starvation period and is used as an energy source for the contractile process in the face of a lidocaine-induced blockade in glycolysis.

• The korean journal of orthodontics
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• v.5 no.1
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• pp.43-50
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• 1975

항암화학요법제인 5-FUR이 백서의 구개발육에 미치는 영향을 연구코자 20수의 신생백서를 반씩 나누어 실험군에는 체중kg당 25mg의 동 약제를 2회 복강내 주사하고 대조군에는 생리적 식염수만을 주사한 후 제 1, 3, 7, 14 및 21일에 각각 2수씩 도살하였다. 또한 도살 2시간전에 체중 gm당 $5{\mu}Ci$의 $H^3-TDR$을 주사하여 자기방사법적으로 처리 관찰하였다. 결과는 다음과 같다. 1. labeling index는 실험일자의 경과에 따라 점차 감소하였다. 2. 5-FUR의 억제작용이 골아세포층과 경구개의 상피층에서 제 7일에 가장 강하게 나타났고 제 14일부터는 감소되는 경향을 나타내었다. 3. 연구개의상피층과 glandular gene에서는 5-FUH의 억제효과가 제 3일에 가장 심히 나타났으며 제 7일부터는 감소되었다. 4. 5-FUR의 억제효과는 점차 감소되어 제21일에는 대조군과의 차이가 현저히 감소하였다. 5. 골아세포층이 5-FUR의 영향을 가장 심하게 받는 반면에 그 회복도 가장 빨랐다.

• Journal of the Korean Society of Food Science and Nutrition
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• v.42 no.6
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• pp.904-910
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• 2013

The aim of this study was to investigate the eating behavior and nutritional status of subjects according to their purpose of exercise. A total of 214 subjects, 20 to 30 years of age, who visited fitness centers in Seoul were enrolled. Anthropometrics, exercise habits, nutritional knowledge, and eating behaviors were analyzed using a questionnaire. Nutritional status was assessed by serial 24 h recalls. The subjects were divided into two groups based on their purpose of exercise: increasing muscle (Muscle growth, n=107) or losing body weight (Weight loss, n=107). The Muscle growth group contained a higher percentage of men, whereas the Weight loss group contained a higher percentage of women. The Muscle growth group showed significantly higher scores of nutritional knowledge and eating behaviors compared to the Weight loss group. The Muscle growth group also had a significantly higher intake of energy and protein compared to the Weight loss group. In fact, the intake of energy in the Weight loss group was lower than the estimated energy requirement (EER) for both men and women subjects. The intake of protein in the Muscle growth group was twice as much as the recommended nutrient intake (RNI). The intake of calcium in both groups was less than the RNI. In conclusion, those who exercised with the aim of increasing muscle took excess dietary protein and those who exercised with the aim of weight loss had a lower energy intake than the EER.

• Journal of the East Asian Society of Dietary Life
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• v.25 no.1
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• pp.30-38
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• 2015

The purpose of this study was to compare energy intake according to expected body mass index (BMI) in adolescents. A total of 280 middle school students were divided into current or/and expected obesity groups (underweight group; UWG, normal weight group; NWG, and overweight group; OWG) by BMI to compare energy intake and perception on body shape and weight control. The average age of total subjects was 15 years, and the distributions of boys and girls were 52.5% and 47.5%, respectively. The distribution of boys and girls was not significantly different among current obesity groups but was among expected obesity groups (15% and 82% in UWG vs. 71.4% and 16.5% NWG vs. 13.6% and 1.5% in OWG; P<0.001), indicating that girls wanted to lose weight more than boys. For body shape, most subjects in current obesity groups responded "fitness" in UWG (38.7%), "fitness" and "slightly chubby" in NWG (45.5% and 39%), and "slightly chubby" in OWG (65.2%), showing a significant difference (P<0.001). For interest in weight control, most subjects responded "average" in current UWcinterested" in current OWG (52.2%), whereas they responded "very interested" in expected UWG (55.7%), "average" in expected NWG (51.2%), and "not interested" in expected OWG (45.5%), showing a significant difference (P<0.001). The percentage of subjects with experience with weight control was significantly high in current OWG (71.7%), NWG (51.2%) and UWG (34.2%) as well as in expected UWG (57.3%), NWG (40.2%) and OWG (36.4%) in descending order (P<0.001). The daily energy intake of total subjects was 2,057.1 kcal without any significant difference among current obesity groups. However, it was significantly lower in expected UWG than expected NWG and OWG (1,943.1 kcal vs. 2,165.0 kcal or/and 2,152.1 kcal; P<0.001). To sum up these results, girls wanted to lose weight more than boys. The more students wanted to lose weight, the greater their experience and interest in weight control and the lower their energy intake.

• Journal of the Korean Society of Food Science and Nutrition
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• v.22 no.1
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• pp.19-26
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• 1993

In this study rats in fasting or fed protein free restricted diet including only fat showed much lowered level of serum cholesterol and triglyceride accompanied by utmost weight loss and high level of blood urea nitrogen indicated the tissue degradation, especially in liver with signs of damage or necrosis of hepatic parenchymal cell leading to elevated glutamic pyruvate transaminase value and to death. Rats fed only perilla oil in starvation or as fat source in normal diet dropped down the level of serum cholesterol and triglyceride compared to beef tallow fed rat. But with evidence of glutamic pyruvate transaminase values which was significantly elevated long term ingestion of perilla oil is likely to cause the lesion or any damage of hepatic function.

• Journal of the Korean Society of Food Science and Nutrition
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• v.35 no.4
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• pp.416-421
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• 2006

Among the oriental medicine compounds, sulfur is known as a heat-generation material in a human body. Heat-generation reaction results in the consumption of energy source. Some oriental herbs are used to treat obesity and blood lipid composition. Therefore, we hypothesized that a sulfur containing oriental medicine compound, called as Hangbisan, could help weight loss of experimental rats. This study was designed to observe the change of weight of Sprague-Dawley (SD) rats that had been fed with high-fat diet containing 10% cellulose or Hangbisan for 9 weeks. Hangbisan affected the weight loss of rats as reducing the level of plasma cholesterol and triglyceride and increasing the level of HDL-cholesterol. Thus, this study revealed Hangbisan have an anti-obesity effect and a potential role for anti-obesity agent in the application of oriental medicine compounds.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.6
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• pp.893-898
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• 2003

This study was carried out to investigate the effect of body weight reduction of noddle contained glucomannan in high fat diets-induced obese rats. Male Spraque-Dawley rats were randomly assigned to control and high fat diets groups for 4 weeks. Four weeks later, the control and high fat diet grpups were rearranged into 4 groups by different levels of nuddle containing glucomannan. After 5 weeks of feeding, serum and whole blood was analyzed. Obesity index was significantly lower in the group fed nuddle contained glucomannan than that of high fat diet groups. The status of white blood cells in hematological examination was significantly higher in rats fed high fat diet and was not significantly different by fed nuddle. Serum albumin levels were not significantly different although glucose levels in serum was significantly different among groups. Serum triglyceride and Total cholesterol levels were the highest levels in rats fed high fat diets and showed the lowest levels in rats fed nuddle.

• Proceedings of the KSCN Conference
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• 2003.05a
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• pp.119-119
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• 2003

최근 체형에 대한 인식의 변화로 국내에서는 체중조절이 사회적인 문제로 다루어질 만큼 커다란 관심의 대상이 되고 있으며, 체중조절을 시도하는 사람들도 급속히 증가하고 있다. 이에 저열량식단과 특수영양식품 등을 이용한 다양한 형태의 비만관리프로그램과 영양교육프로그램이 등장하면서 이들 프로그램의 체중감량효과에 대한 연구가 활발하게 진행되어져 오고 있다. (중략)

• The Monthly Diabetes
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• s.134
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• pp.38-39
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• 2001

• 대한위암학회:학술대회논문집
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• 2001.11a
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• pp.39-39
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• 2001