• Title/Summary/Keyword: 체외수정 시술

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Age or Basal Serum FSH Levels; Which One is Better for Prediction of IVF Outcomes in Patients with Decreased Ovarian Reserve? (난소의 기능이 저하된 불임 환자에서 연령 및 기저 혈중 FSH 수치가 체외수정시술의 예후에 미치는 영향에 관한 연구)

  • Yu, Young;Kim, Min-Ji;Cho, Yeon-Jean;Yeon, Myeong-Jin;Ahn, Young-Sun;Cha, Sun-Hwa;Kim, Hye-Ok;Park, Chan-Woo;Kim, Jin-Young;Song, In-Ok;Koong, Mi-Kyoung;Kang, Inn-Soo;Jun, Jong-Young;Yang, Kwang-Moon
    • Clinical and Experimental Reproductive Medicine
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    • v.34 no.3
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    • pp.189-196
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    • 2007
  • Objectives: The purpose of this study is to investigate the clinical significance of age and basal serum FSH in predicting the outcomes of in vitro fertilization (IVF) in patients with poor-ovarian response. Methods: From January 2000 to December 2004, 85 second IVF cycles of 85 poor-ovarian response patients under the age of 42 with a back-ground of the first IVF cycles at our infertility center and 5 or less oocytes were retrieved and their basal serum FSH levels of 15$\sim$25 mIU/ml were enrolled in this study. Exclusion criteria were patients with a male factor for the etiology of infertility and undergoing genetic diagnosis of embryo such as PGD. Flare-up protocol was used for ovarian stimulation in all cases. Results: When we stratified the study groups by patient's age, the younger age group (age<35, n=35) showed significantly higher implantation rate (19.0% versus 4.0%, p<0.05) and higher ongoing pregnancy rate (100% versus 14.3%, p<0.05) than the older age group (age$\geq$35, n=50). And then, when we stratified the study populations by basal serum FSH level, the lower FSH group (basal serum FSH<20 mIU/ml, n=58) showed significantly higher number of retrieved oocytes (4.6$\pm$0.7 versus 2.2$\pm$0.5, p<0.05) and lower cancellation rate (19.0% versus 55.6%, p<0.05) than higher FSH group (basal serum FSH$\geq$20 mIU/ml, n=27). Conclusions: In conclusion, it was suggested that the patient's age could predict the IVF outcomes in respect to its potency of pregnancy and ongoing pregnancy. Serum basal FSH levels could predict more accurately the ovarian response of cycle, but not clinical outcomes.

Two Cases of Combined Pregnancy Following IVF-ET (체외수정 시술 후 발생된 병합임신 2례)

  • Lee, Kyung-Ah;Kwak, Yang-Soo;Han, Kuk-Sun;Koh, Min-Whan;Lee, Tae-Hyung
    • Journal of Yeungnam Medical Science
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    • v.14 no.1
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    • pp.262-268
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    • 1997
  • Combined intrauterine and ectopic (heterotopic) pregnancy occurs in approximately 1 in 30,000 spontaneous gestations. Heterotopic gestations are increased in women who have had reconstructive pelvic surgery, pelvic inflammatory disease and artificial ovarian hyperstimulation. Patients who require assisted reproductive technologies, such as in vitro fertilization / embryo transfer and gamete intrafallopian transfer, also have an increased risk of a heterotopic pregnancy. We experienced two cases of combined pregnancy following IVF-ET. Following is a report of these cases with a brief review of references.

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Pregnancy following IVF-ET in an Immunologic Infertility Woman (면역학적 불임환자에서 체외수정 시술에 의한 임신 1예)

  • Pang, Myung-Geol;Oh, Sun-Kyung;Kim, Seok-Hyun;Shin, Chang-Jae;Kim, Jung-Gu;Moon, Shin-Yong;Lee, Jin-Yong;Chang, Yoon-Seok
    • Clinical and Experimental Reproductive Medicine
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    • v.19 no.2
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    • pp.189-192
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    • 1992
  • In vitro fertilization and embryo transfer was performed in a patient with immunologic infertility. This patient delivered at preterm a normal healthy male infant.

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A Observation of IVF-ET Program in the Reproductive Center of the Ohio State University Hospital (체외수정 및 배아이식:Ohio State University의 시술과정을 중심으로)

  • Kang, Kil-Chun
    • Clinical and Experimental Reproductive Medicine
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    • v.16 no.2
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    • pp.187-204
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    • 1989
  • This is a report concerning IVF-ET program and its outcomes of the reproductive center of the Ohio State University(OSU). The pregnancy rate/laparascopy in the OSU reproductive center was average 12.2%. However, the fertilization rate was lower than other reporters. The other problem of the OSU reproductive center was that there was no success in the field of cryopreserved embryo and donor embryo. Therefore, many aspects such as hyperstimulation protocol, culture systems, and embryo transfer technique should have to be reevaluated in order to enhance the outcome of IVF-ET program in the OSU reproductive center.

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