• Title/Summary/Keyword: 철(II)

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Effects of Eucommia Ulmoides Oliver and Treadmill Exercise on the Osteoporosis of Rats Caused by Glucocorticoid Induction (두충 추출물 투여와 트레드밀 운동이 골다공증 유발 백서의 골대사에 미치는 영향)

  • Yoon, Seok-Joo;Kim, Kyung-Yoon;Kim, Gye-Yeop;Nam, Ki-Won;Sim, Ki-Cheol;Kim, Eun-Jung;Chung, Hun-Woo;Kim, Hyung-Woo;Kim, Gi-Do
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.22 no.4
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    • pp.884-890
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    • 2008
  • This study classified 40 of 10 weeks-old male Sprague Dawley rats which have osteoporosis caused by glucocorticoid(GC) induction into four groups of 10 rats and made the subjects medicated them Eucommia ulmoides Oliver and participate in treadmill exercise. Group I was non-treatment after GC induction; Group II was treadmill exercise after GC induction; Group III was Eucommia ulmoides Oliver feeding after GC induction; Group IV was treadmill exercise and Eucommia ulmoides Oliver feeding after GC induction. In the bone mineral density and bone strength test, there was a statistically significant difference between the group I, II, III compared to group IV(p<0.05). In the osteocalcin level as one of bone formation indexes, there was a statistically significant difference between the group I, II, III compared to group IV(p<0.05). In respect to the calcium there was a statistically significant difference between group I, II, III compared to group IV(p<0.05). In respect to histological findings, the group IV showed mild femur disruption and lytic change on femur section. The above results suggests that Eucommia ulmoides Oliver medicated and treadmill exercise is effective to prevention and treatment of osteoporosis.

Purification and Enzymatic Properties of Myrosinase in Korean Mustard Seed(Brassica juncea) (한국산 겨자중 Myrosinase의 정제 및 효소학적 특성)

  • 신창식;서권일;강갑석;안철우;김용관;심기환
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.25 no.4
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    • pp.687-694
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    • 1996
  • Myrosinase was purified from Korean mustard seed(Brassica juncea) by a sequential process of DEAE-cellulose, concanavalin A-sepharose, and Superose 6 chromatography. The molecular weight of puri-fied myrosinase(II-2) determined by SDS-polyacrylamide electrophoresis was 67KD. About a 248-fold purification for myrosinase II-2 was obtained after Superose 6 chromatography. Optimum pH of the myrosinase was 7.0 and optimum temperature of the enzyme was $3^{\circ}C.$ The enzyme was stable at pH 7.0, and below $30^{\circ}C.$ Cu, Hg and Fe ion significantly inhibited the enzyme activity, but ascorbic acid enhanced, resulting in a maximum activity by 1mM ascorbic acid. Among tile ascorbic acid ana-logues, dehydroascorbic acid inhibited the enzyme activity, whereas others showed a little effect. Reducing agents such as 2-mercaptoethanol and dithiothreitol inhibited the enzyme activity, but the reducing agents with ascorbic acid was enhanced enzyme activity.

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Postoperative Pain Control after Cesarean Section with Transdermal Fentanyl Patch (Fentanyl 첩포를 이용한 제왕절개술후 통증 조절)

  • Lee, Jong-Cheol;Kim, Tae-Jung;Han, Jeong-Uk;Lim, Hyun-Kyoung;Song, Jang-Ho;Lee, Hong-Sik;Cha, Young-Deog;Park, Dong-Ho;Lee, Sung-Keun
    • The Korean Journal of Pain
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    • v.12 no.2
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    • pp.211-216
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    • 1999
  • Background: Transdermal fentanyl patch (TDFP) is a simple, noninvasive analgesic with continuous effect. The aim of this study was to evaluate the postoperative analgesic effect of TDFP. Methods: Sixty healthy patients undergoing cesarean section were divided into 3 groups. Postoperative pain was controlled with different methods; Group I: application of TDFP-$25{\mu}g/hr$, Group II: intramuscular injection of ketoprofen; Group III: continuous epidural block. Pain scores (numerical rating scale, NRS), number of patients who needed additive ketoprofen injections and side effects were recorded at 8, 20, 32, 44 hours postoperatively. Results: There was no significanant difference in pain score between Group I and Group II. The numbers of patients who need additive ketoprofen injections were lower in group I than group II. Pruritis (25%), nausea/vomiting (10%), leg numbness (40%) was experienced in group III, but not in Group I & II. Conclusions: TDFP-$25{\mu}g/hr$ for postoperative pain control is simpler and more convinient than intramuscular injection of analgesics.

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Surgical Treatment of Atrial Septal Defect in Adult Patients (성인의 심방중격 결손의 외과적 치료)

  • Lee, Dong-Hyup;Lee, Jung-Cheul;Han, Sung-Sae
    • Journal of Yeungnam Medical Science
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    • v.9 no.2
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    • pp.321-326
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    • 1992
  • The study consisted of all patients over 35years old undergoing surgical repair of atrial septal defect for the period from June 1985, to August 1992. The following results were observed. 1. ASD was closed with patch in 11(73%) patients. 2. The relationship of pulmonary artery systolic pressure to Qp/Qs ratio was not significant. 3. Before operation 6 patients were in NYHA functional class II, 8 were in class III, After operation 8 patients were in class I, 6 were in class II. 4. Atrial fibrillation has persisted in 3 patients and returned regular rhythm in 1 patient after surgery. 5. There was no operative mortality and we had good surgical results regardless of patient's age.

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Effects of Soybean Sprouts Extract Isoflavone In the Osteoporosis of Rats Caused by Ovariectomy (콩나물 추출 이소플라본이 난소적출로 유발된 골다공증 백서의 골대사에 미치는 영향)

  • Kim, Gye-Yeop;Cho, Gun-Sik;Chung, Hun-Woo;Kim, Gi-Do;Sim, Ki-Cheol;Kim, Kyung-Yoon
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.23 no.2
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    • pp.426-432
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    • 2009
  • The overall purpose of this study was to investigate the effects of level of isoflavones supplementation on bone metabolism in osteoporosis rats. The effects of level of isoflavones supplementation on calcium and osteocalcin blood level, femur/body weight, bone mineral density(BMD) and bone strength were inspected in this study. This study classified 28 of 12 weeks-old male Sprague Dawley rats which have osteoporosis caused by ovariectomy into four groups of 7 rats and made the subjects medicated them isoflavone. Group I was non-treatment after osteoporosis(control); Group II was low-dose isoflavone(20 mg/kg) feeding after osteoporosis; Group III was middle-dose isoflavone(40 mg/kg) feeding after osteoporosis; Group IV was high-dose isoflavone(80 mg/kg) feeding after osteoporosis; In the calcium and osteocalcin level as one of bone formation indexes, there was a statistically significant difference between the group II, III, IV compared to group I. In respect to the femur/body weight, there was a statistically significant difference between the group II, III, IV compared to group I. In the bone mineral density and bone strength test, there was a statistically significant difference between the group II, III, IV compared to group I. The above results suggests that isoflavone medicated is effective to prevention and treatment of osteoporosis.

Catalytic Activity of Metal-phthalocyanine Bonded on Polymer for Decomposition of Hydrogen Peroxide (고분자에 결합된 금속-프탈로시아닌의 과산화수소수 분해반응에 대한 촉매활성)

  • KimKong Soo 김공수;Yong Chul Chun;Young Woo Lee;Sang Ho Lee
    • Journal of the Korean Chemical Society
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    • v.33 no.6
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    • pp.662-668
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    • 1989
  • The decomposition reaction of hydrogen peroxide was carried out by using metal-4,4',4",4"'-tetraaminophthalocyanine [Mt-$PcNH_2$, Mt = Fe(III), Co(II)] supported on poly (styrene-co-methacrylic acid), in heterogeneous aqueous system. These catalysts showed a catalse-like activity and Fe(III)-$PcNH_2$ supported on the copolymer was particularly effective for the decomposition of hydrogen peroxide. It was found that the rate of decomposition increased smoothly in the higher pH region and catalytic reaction was interfered by adding $CN^-,\;CNS^-,\;{C_2O_4}^{-2},\;I^-$ ions. The kinetics of the catalytic reaction was also investigated and the reaction proceeds according to the Michaelis-Menten type mechanism.

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Design of Spontaneous Acoustic Field Reproducing System (II) (능동형 음장조성시스템의 설계(II))

  • Kook, Chan;Jang, Gil-Soo;Chon, Ji-Hyun;Shin, Yong-Gyu;Min, Byoung-Chul
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2006.05a
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    • pp.964-969
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    • 2006
  • The soundscape is a novel attempt to offer comfortable sound environments at the urban public spaces by adding pleasant sounds and removing unagreeable ones. Most important factors to be considered therein are to determine what kind of sounds to offer and how to adjust them to the changing circumstances. But nowadays, the audio system provided in the almost every urban public spaces is just only a PA system with CD player or radio broadcasting music, the provided sound is only intended by the operator. Furthermore, providing the soundscape which fits to the situation and the atmospheric conditions needs enormous effort and time, it is almost impossible with the existing PA systems which installed in the public spaces nowadays. Thus, the new sounds cape reproduction system was developed on the basis of the prior VAFSS(Virtual Acoustic Field Simulation System) systems, which has the artificial intelligence to read out the mood of the field and select the appropriate soundscape to reproduce. In this new system, various environmental sensors with standard voltage, current or resistance output are available simultaneously, and the monitoring with video and sound became available via the TCP/IP communication protocol. The update and control of this system can be very convenient, so the money, time and the effort of maintaining and providing soundscape on the public spaces can be enormously saved. This new soundscape reproducing system was named as Virtual Acoustic Field Simulation System II (V AFSS II).

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Effects of Drought Stress on Photosynthetic Capacity and Photosystem II Activity in Oplopanax elatus (수분스트레스가 땃두릅나무의 광합성 능력 및 광계 II의 활성에 미치는 영향)

  • Lee, Kyeong Cheol;Kim, Sun Hee;Park, Wan Geun;Kim, Young Seol
    • Korean Journal of Medicinal Crop Science
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    • v.22 no.1
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    • pp.38-45
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    • 2014
  • This study was performed to investigate the physiological responses of Oplopanax elatus by water condition. Drought stress was induced by withholding water for 26 days. The results show that $P_{N\;max}$, SPAD, gs, E and Ci were significantly decreased with decreasing of soil moisture contents. However, AQY and WUE were decreased slightly only at 26 day. This implies that photosynthetic rate is reduced due to an inability to regulate water and $CO_2$ exchange through the stomatal. According to JIP analysis, ${\Phi}_{PO}$, ${\Psi}_O$, ${\Phi}_{EO}$ and $PI_{ABS}$ were dramatically decreased at 21 day and 26 day, which reflects the relative reduction state of the photosystem II. On the other hand, the relative activities per reaction center such as ABS/RC, TRo/RC were significantly increased at 26 day. Particularly, Dio/RC and DIo/CS increased substantially under drought stress, indicating that excessive energy was consumed by heat dissipation. These results of chlorophyll a fluorescence show that the sensitivity changes photosystem II activity. Thus, according to the results, O. elatus was exhibited a strong reduction of photosynthetic activity to approximately 10% soil moisture contents, and JIP parameters could be useful indicator to monitor the physiological states of O. elatus under drought stress.

Enantioselective Epoxide Synthesis on the Chiral Salen Catalyst having a Transitional Metal Salt (전이금속염 함유 키랄 살렌 촉매에 의한 광학선택적 에폭사이드의 합성)

  • Guo, Xiao-Feng;Kawthekar, Rahul B.;Kim, Geon-Joong
    • Korean Chemical Engineering Research
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    • v.46 no.4
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    • pp.769-776
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    • 2008
  • The stereoselective synthesis of chiral terminal epoxide is of immense interest due to their utility as versatile starting materials as well as chiral intermediates. In this study, new chiral Co(salen) complexes bearing cobalt(II) chloride, iron(III) chloride and zinc(II) nitrate have been synthesized and characterized. The mass and EXAFS spectra provided the direct evidence of formation of complex. Their catalytic activity and selectivity have been demonstrated for the asymmetric ring opening of terminal epoxides such as styrene oxide and phenylglycidylether by hydrolytic kinetic resolution technology and for the synthesis of glycidyl buthylate. The easily prepared complexes exhibited very high enantioselectivity for the asymmetric ring opening of epoxides with $H_2O$ nucleophile, providing enantiomerically enriched terminal epoxides (>99% ee). The newly synthesized chiral salen showed remakablely enhanced reactivity with substantially low loadings. The system described in this work is very efficient for the sinthesis of chiral epoxide and 1,2-diol intermediates.

Analysis and Prediction of Prosodic Phrage Boundary (운율구 경계현상 분석 및 텍스트에서의 운율구 추출)

  • Kim, Sang-Hun;Seong, Cheol-Jae;Lee, Jung-Chul
    • The Journal of the Acoustical Society of Korea
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    • v.16 no.1
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    • pp.24-32
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    • 1997
  • This study aims to describe, at one aspect, the relativity between syntactic structure and prosodic phrasing, and at the other, to establish a suitable phrasing pattern to produce more natural synthetic speech. To get meaningful results, all the word boundaries in the prosodic database were statistically analyzed, and assigned by the proper boundary type. The resulting 10 types of prosodic boundaries were classified into 3 types according to the strength of the breaks, which are zero, minor, and major break respectively. We have found out that the durational information was a main cue to determine the major prosodic boundary. Using the bigram and trigram of syntactic information, we predicted major and minor classification of boundary types. With brigram model, we obtained the correct major break prediction rates of 4.60%, 38.2%, the insertion error rates of 22.8%, 8.4% on each Test-I and Test-II text database respectively. With trigram mode, we also obtained the correct major break prediction rates of 58.3%, 42.8%, the insertion error rates of 30.8%, 42.8%, the insertion error rates of 30.8%, 11.8% on Test-I and Test-II text database respectively.

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