• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.37 no.3
• /
• pp.205-212
• /
• 2013

The objective of this study was to investigate the feasibility of replacing a conventional plate fin-tube evaporator with a spiral fin-tube evaporator by comparing the performance of domestic refrigerator-freezers adopting either the plate fin-tube evaporator or spiral fin-tube evaporator. Experiments were conducted for the domestic refrigerator-freezers using either a 2-column and 15-row plate fin-tube evaporator or three spiral fin-tube evaporators with 11, 13, and 15 tube rows (N). The optimum refrigerant charge decreased with a decrease in the number of tube rows. The power consumptions of the domestic refrigerator-freezers using the spiral fin-tube evaporators with N = 11 and 13 were 2.8% and 1.5% lower than those using the plate fin-tube evaporator, respectively. In addition, the cooling capacity of the spiral fin-tube evaporator with N = 13 was 3%-7% higher than that of the plate fin-tube evaporator under the frosting condition. In a cooling speed test, all of the evaporators showed similar performances.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.12 no.8
• /
• pp.3541-3546
• /
• 2011

Autophagy is an evolutionarily conserved lysosomal pathway for degrading cytoplasmic proteins, macromolecules, and organelles in addition to recycling protein and ATP synthesis. Although autophagy is very important during embryogenesis, the mechanism underlying the dynamic development during this process remains largely unknown. In order to obtain insights into autophagy in early embryo development, we analyzed gene expression levels of autophagy-related genes (ATGs) in mouse embryos developing in vitro. Using real time RT-PCR technique, ATGs including Atg2a, Atg3, Atg4b, Atg5, Atg6, Atg7, Atg9a, and Wipi3, as maternal transcripts, were only up-regulated in 1-cell embryo stage before zygotic genomic activation (ZGA), and then expression decreased from 2-cell to blastocyst embryo stage. ATGs including Dram and Atg9b were expressed abundantly in 1-cell embryo state and in blastocyst embryo stage, athough Atg8 and Ulk1 were constantly expressed during preimplantation stage. However, Atg4d were only up-expressed from 4-cell to blastocyst stage. These results suggest that autophagy is related in mouse embryo, which possibly gives an important role for early development.

• Journal of the Korea Concrete Institute
• /
• v.25 no.1
• /
• pp.115-123
• /
• 2013

The steel industry, a representative industry that significantly consumes raw materials and energy, produces steel as well as a large amount of by-product steel slag through the production process. The vast habitat foundation of marine life has been destroyed due to recent reckless marine development and environment pollution, resulting in intensification of the decline of marine resources, and a solution to this issue is imperative. In order to propose a method to recycle large amounts of by-product slag into a material that can serve as an alternative to natural aggregate, the engineering properties and applicability for each mixing factor of environment friendly porous concrete as a material for the composition of marine ranches were evaluated in this study. The test results for percentage of voids per mixing ratio revealed that the margin of error for all conditions was within 2.5%. The compressive strength test results showed that the most outstanding environmental friendly porous concrete can be manufactured when mixing 30% slag aggregate and 10% specially treated granular fertilizer for the optimum volume fraction. As concrete for marine applications, the best seawater resistance was obtained with mixing conditions for high compression strength. An assessment of the ability to provide a marine life habitat foundation of environmentally friendly porous concrete showed that a greater percentage of voids facilitated implantation and inhabitation of marine life, and the mixing of specially treated granular fertilizer led to active initial implantation and activation of inhabitation. The evaluation of harmfulness to marine life depending on the mixture of slag aggregate and specially treated granular fertilizer revealed that the stability of fish is secured.

• Journal of the korean Society of Automotive Engineers
• /
• v.3 no.2
• /
• pp.10-17
• /
• 1981

연료의 가격이 높아지고 대체연료의 개발이 급속동로 진전되고 있는 오늘날 디이젤기관은 열효율 의향상과 장래연료에의 대응이 중요한 과제로 되어있다. 대체연료로서 유망시되고있는 석탄약화 연료, 알코호르 쉘오일(Shell Oil)등이 앞으로 싱용화되면 제업이나 플랜트의 규모에 따라서는 가격뿐만 아니라 그질에도 큰 차이가 있게되고 정도나 비중의 변화등으로 대표적인 세탄가의 저화가 예상되어서 현상 디이젤기관의 연소방식 그대로는 이에 대응 할 수 없게될 가능성이 높다. 이들에 대응하기의한 하나의 방법으로서 기관을 단열화함으로써 냉각손실을 저장시키고, 높아진 배기에너지를 축출력으로서 다시 회수하는 단열터어보 컴파운드엔진의 개념이 있다. 이 렇게 하면 열효율의 대표적인 개성과 아울러 단열화하여서, 연소실의 벽온이 높아지므로 저세 탄가 연료의 연소도 가능하게 된다. 단열기관의 착상은 1940년대 융커어스사의 2-사이클 수평 대향기관에 이미 일부 채용되었었고, 또 터어보 컴파운드에 의한 배열의 회수도 Lycoming사 R3350 엔진등에서 실용화되었던 예가 있다. 그러나 이들을 동시에 채용하여 대돌적인 연비저 강효과를 추구한 실제의 예로서는 근년 미국 육군의 위탁으로 Cummis사가 연구성과를 발효하고 있는것 뿐이다. 그리고 일본의 Komatsu사가 또한 독자적으로 단열터어보 컴파운드기관의 연 구를 하고 있다. 다음은 그 기관을 소개하고 또한 다종연료성등 단열엔진의 특성에 대하여 설명 한다.

• Journal of radiological science and technology
• /
• v.18 no.2
• /
• pp.75-86
• /
• 1995

Embryos and fetuses are more sensitive to various environmental agents than adults of children biological effects following the exposure, such as intrauterin, malformation, have intimate conception with the prenatal exposure. There have been many studies on radiation and other agent. However, imformation about the ultrasound effects is limited. It is very important to study the effect of ultrasound with these kinds of fatera in consideration of ultrasound protection and safty. In this study, embryonic and fefal effects of ICR mouse embryos irradiated on 24, 48, 12 and 192 hpc of preimplantation and organogenesis period at the intensity of $0.5{\sim}3\;W/cm^2$ were investigated. Many type of external malformation observed in mouse irradiated on 72 hpc and 192 hpc. However, the embryos irradiated on 24 hpc and 48 hpc, at witch embryos had less then 6 cells and were pre-compaction stage, had no sensitivity for external malformation. The threshold doses of external malformation in mouse irradiated on 72 hpc and 192 hpc, at which embryos were consisted of $16{\sim}32$ cells and neural formation stage, were $1\;W/cm^2$ and $0.5\;W/cm^2$.

• Journal of Science and Technology Studies
• /
• v.3 no.2 s.6
• /
• pp.1-27
• /
• 2003

Complexity paradigm is a scientific amalgam that aims to unite a range of theoretical perspectives and research agendas across natural and social sciences. Proponents of complexity paradigm lay claims to an increasing number of areas of study, including artificial life, interpersonal networks, internal/international patterning of organizations, mapping of cyberspace, etc. All of those can be subsumed under the title, 'complexity turn.' Owing to the idea of open system, complexity paradigm has developed a number of new concepts/themes/perspectives that help to account for the complex mechanism of living and non-living creatures. A complex system comprises a number of properties such as disequilibrium, nonlinearity, dissipative structure, self-organization fractal geometry, autopoiesis, coevolution. Following a brief introduction to theoretical development, those properties are succinctly discussed. The complexity turn has provided a wealth of insights that enable to analyze system operations of any kind. It contributes a lot to illuminating the working of social system as well. The most remarkable attempt may be Niklas Luhmann's 'neofunctional system theory.' Merits and shortcomings of complexity paradigm were examined and its future prospect were assessed with the conclusion that complexity paradigm would continue to be useful both as effective transdisciplinary framework and powerful analytical tool.

• Transactions of the Korean Society of Mechanical Engineers B
• /
• v.34 no.5
• /
• pp.515-522
• /
• 2010

The objective of this study is to investigate the air-side heat transfer characteristics of a spirally-coiled circular fin-tube heat exchanger for various geometric parameters under non-frosting conditions. The heat transfer characteristics of the heat exchanger were analyzed with respect to heat exchanger geometries, and then, the characteristics were compared with those of rectangular-plate fin-tube heat exchangers with discrete fins. The heat transfer coefficient increased with a decrease in the number of tube rows and an increase in the fin pitch. The optimum length of the L-foot was 2.7 mm. In addition, the heat transfer rate increased with a decrease in the tube pitch and the tube thickness. The heat transfer coefficient of the spirally-coiled circular fin-tube heat exchanger was 24.3% higher than that of the rectangular-plate fin-tube heat exchanger.

• Clinical and Experimental Reproductive Medicine
• /
• v.33 no.1
• /
• pp.25-33
• /
• 2006

Objective: The aim of this study was to investigate whether embryonic stem (ES) cells can be established from isolated blastomeres of mouse embryos. Methods: Blastomeres were separated from mouse (C57Bl/6J) 2- or 4-cell embryos. Isolated blastomeres or whole 4-cell embryos were co-cultured with mitosis-arrested STO feeder cells in DMEM supplemented with recombinant murine leukemia inhibitory factor and ES-qualified fetal bovine serum. After the tentative ES cell lines were maintained from isolated blastomeres or whole embryos, some of them were frozen and the others were sub-cultured continually. Characteristics of tentative ES cell lines as were evaluated for specific genes expressions with immunocytochemistry and RT-PCR. Results: One ES cell line (3.0%) was established from isolated blastomere of 2-cell embryo and one cell line (4.0%) from isolated two blastomeres of 4-cell embryo. And five cell lines (16.7%) were established from whole 4-cell embryos. Both cell lines from isolated blastomere and whole embryo expressed mouse ES cell specific markers such as SSEA-1, Oct-4 and alkaline phosphatase. Marker genes of three germ layers were expressed from embryoid bodies of both cell lines. Conclusion: This study suggests that mouse ES cells could be established from isolated blastomeres, although the efficiency is lower than whole embryos. This animal model could be applied to establishment of autologous human ES cells from biopsied blastomeres of preimplantation embryos in human IVF-ET program.

• Clinical and Experimental Reproductive Medicine
• /
• v.37 no.2
• /
• pp.143-151
• /
• 2010

Objective: The aim of this study was to compare day 3 embryo transfer (D3ET) with day 5 ET (D5ET) in fresh in vitro fertilization (IVF) cycle on pregnancy outcomes. Methods: We conducted a retrospective matched case control study that included 90 women with D3ET and 90 women with D5ET from January 2007 to June 2009. Subjects were matched for reproductive profiles and IVF cycle characteristics. Two good quality embryos were transferred in both groups. Pregnancy rates (PR), implantation rate, and multiple PR were compared. Results: Demographics, stimulation parameters and embryological data were comparable in both groups. Main pregnancy outcomes with D3ET and D5ET groups were not statistically different: implantation rate (39.4% vs. 32.8%), positive PR (57.8% vs. 46.7%), clinical PR (53.3% vs. 45.6%), ongoing PR (50.0% vs. 42.2%), respectively. Both groups showed high multiple PR (37.5% vs. 34.1). Conclusion: D5ET may not be beneficial and necessary in comparison with D3ET on pregnancy outcomes, and elective single ET should be considered to decrease multiple pregnancies in women with favorable conditions and good quality embryos undergoing IVF.

• Clinical and Experimental Reproductive Medicine
• /
• v.37 no.1
• /
• pp.65-72
• /
• 2010

Objective: To compare the respective pregnancy outcomes of cycles undergoing elective two cleavage-stage embryos transfer (2ET) and three cleavage-stage embryos transfer (3ET) in fresh in vitro fertilization and embryo transfer (IVF-ET) program. Methods: We conducted a retrospective matched case control study that included 100 women with 2ET and 100 women with 3ET from January 2007 to June 2009. Subjects were matched for reproductive profiles and cycle characteristics. All of transferred embryos in both groups had good qualities. Pregnancy rates (PR), implantation rate, and multiple PR were compared. Results: Demographics, stimulation parameters and embryological data were comparable in both groups. Main pregnancy outcomes with 2ET and 3ET groups were not statistically different; implantation rate (41.0% vs. 35.3%), positive pregnancy rate (58.0% vs. 60.0%), clinical PR (55.0% vs. 59.0%), ongoing PR (51.0% vs. 55.0%), respectively. However, the 3ET group showed significantly higher multiple pregnancy and triplet pregnancy rates (30.9% vs. 50.8%, p=0.031; 1.8% vs. 11.9%, p=0.036, respectively). Conclusion: In women with favorable conditions and good quality embryos undergoing IVF, 2ET can get pregnancy outcomes comparable to those of 3ET and reduce multiple pregnancy (especially, triplet pregnancy).