• 한국융합학회논문지
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• 제10권9호
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• pp.167-172
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• 2019

본 연구는 초기 치매환자를 대상으로 전산화 인지재활프로그램이 전두엽 집행기능 중 생성 이름대기에 미치는 효과를 파악하고, 치매 환자의 조기 언어중재에 관한 기초자료를 제공하였다. 분석 대상은 경증치매환자 29명으로서 전산화 인지재활프로그램(CoTras)을 중재하는 실험군 21명과 지필과 테이블활동 등 전통적인 면대면 언어재활을 중재하는 대조군 8명으로 분류되었다. 실험집단과 대조집단은 모두 12주 동안 순차적 언어 회상 기억훈련, 연합회상 기억훈련, 언어 범주화 기억훈련, 언어통합 기억훈련을 진행하였다. 의미유창성과 음소유창성의 사전검사점수를 공변량으로 통제한 Welch's robust ANCOVA분석 결과, 실험집단과 대조집단은 의미유창성과 MMSE-K의 변화에서 유의미한 차이가 있었다(p<0.05). 반면에, 음소유창성은 실험군과 대조군 모두 기초선단계에 비해서 12주간의 치료 후 유의미하게 증가하였지만 통계적으로 치료방법에 따른 유의미한 차이는 없었다. 본 연구의 결과는 전산화 인지재활프로그램이 전통적인 인지재활에 비해서 의미유창성의 향상에 효과적일 가능성을 시사한다.

• 생물정신의학
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• 제8권2호
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• pp.258-265
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• 2001

Objectives : Chronic alcohol consumption has been known to result in various neurocognitive deficits. Many neuropsychological studies revealed that the major disturbances occurred in the executive function, learning and short-term memory, visuospatial performance function, perceptuo-motor skills, and abstraction and problem solving abilities. This study was done to identify which cognitive areas might be mainly affected. Methods : The cognitive disturbance was evaluated using the Korean Version of the Mini Mental State Examination(MMSEK) and the 7 Minute Screen(7MS) in male inpatients with alcohol dependence(N=3 : as well as in age and education level matched healthy male controls(N=30). Four individual tests of the 7MS were consisted of the Benton Temporal Orientation Test, the Enhanced Cued Recall, the Clock Drawing and the Category Fluency. Results : 1) The average scores of four individual test of the 7MS for the alcoholics were $2.77{\pm}4.38$ for the Benton Temporal Orientation Test, $13.90{\pm}2.02$ for the Memory Test(the Cued Recall $6.77{\pm}1.94$, the Uncued Recall $7.10{\pm}2.45$), $5.84{\pm}1.86$ for the Clock Drawing, and $12.58{\pm}3.29$ for the Category Fluency. Except the Benton Temporal Orientation Test, there were statistically significant differences between test scores of alcoholics and those of controls(p<0.01). 2) The alcoholics who had MMSE-K score <24 were 9.68%. The average(${\pm}S.D.$) score of the MMSE-K for the patient group($27.23{\pm}2.62$) was significantly(p<0.001) lower than that of the healthy controls($29.20{\pm}1.24$). There were no statistically significant differences between four individual test scores of the 7MS of alcoholics with the MMSE-K score <24(N=3) and those of alcoholics with the MMSE-K score ${\geq}24$(N=28). 3) Four individual test scores of the 7MS seemed to have statistically significant association with such variables as MMSE-K, duration of alcohol drinking, blood magnesium concentration, liver function and thyroid function. Conclusion : Mild deficits of cognitive areas such as orientation, memory, visuospatial abilities and verbal fluency could be found in alcohol dependence.