• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.22 no.12
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• pp.1124-1131
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• 2011

In this paper, image reconstruction algorithm for breast cancer detection using MT(Microwave Tomography) was investigated. The breast cancer detection system under development uses 16 transmit/receive antennas. The signal waveform was a sinusoidal wave at 900 MHz. To solve the 2D inverse scattering problem, we used the 2D FDTD (Finite Difference Time Domain) method for forward calculation and LMA(Levenberg-Marquardt Algorithm) for optimization. The result of the image reconstruction using the numerical phantom by MRI(Magnetic Resonance Imaging) obtained from real patient of breast cancer showed that we can detect the position of the tumor accurately.

• Journal of Veterinary Clinics
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• v.31 no.2
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• pp.112-116
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• 2014

A 2-month-old intact male Pitbull terrier (weighing 1.01 kg) were referred with primary complaints of severe abdominal distension, exercise intolerance, retarded growth, yellow nasal discharge and anorexia. Diagnostic imaging studies found enlarged right atrium partitioned by abnormal membrane, severe pulmonic systolic jets (5.66 m/s of peak velocity) and right-to-left blood shunt at the inter-atrial septum. Based on clinical and diagnostic findings, the case was diagnosed as cor triatriatum dexter complicated with severe pulmonic stenosis and right-to-left shunted patent foramen ovale. Either surgical or interventional therapy has not been attempted, because of unstable patient's condition. Using blood transfusion, oxygen supply and cardiac medications (i.e., sildenafil, spironolactone, enalapril), the dog was recovered.

• Journal of Genetic Medicine
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• v.6 no.1
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• pp.87-90
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• 2009

Cardiofaciocutaneous (CFC) syndrome is characterized by dysmorphic features, cardiac anomalies, and cutaneous abnormalities. CFC syndrome belongs to the class of Noonan-related diseases. CFC syndrome can be clinically differentiated from other Noonan-related diseases by the distinct craniofacial features of sparse hair, a hypoplastic supraorbital ridge, exophthalmos and nystagmus, and skin manifestations such as ichthyosis and hyperkeratosis. However, phenotypes can overlap among Noonan-related syndromes, including CFC syndrome. Recently, several genes in the RAS-MAPK pathway have been identified as disease-causing genes for Noonan-related diseases. Here, we report on a Korean girl diagnosed with CFC syndrome caused by a V-raf murine sarcoma viral oncogene homolog B1 (BRAF) gene mutation, and we discuss the phenotype-genotype heterogeneities in Noonan syndrome and Noonan-related diseases.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.15 no.2
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• pp.93-97
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• 2015

Short-chain acyl-CoA dehydrogenase (SCAD) deficiency is an autosomal recessive hereditary metabolic disorder of mitochondrial fatty acid beta-oxidation. Mutations in the ACADS gene cause short-chain acyl-CoA dehydrogenase deficiency, which is characterized by developmental delay, hypotonia, seizure, and hypoglycemia. Here, we describe one Korean pediatric case of SCAD deficiency, which was diagnosed during newborn screening by tandem mass spectrometry and confirmed by molecular analysis. The level of C4 was typically elevated 5.23 mg/dL (reference range <1.5 mg/dL). This patient had a homozygous mutation [c.1031A>G, p. E344G] in ACADS. Therefore, we present a case of SCAD deficiency in an otherwise healthy neonate and her subsequent development and growth over four years.

• Tuberculosis and Respiratory Diseases
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• v.66 no.3
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• pp.220-224
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• 2009

Coccidioidomycosis is a fungal infection caused by the soil fungus, Coccidioides immitis, which is endemic to the south-western United States. However, the incidence of coccidioidomycosis has recently increased due to the increase in overseas travel to endemic areas. We report a case of pulmonary coccidioidomycosis diagnosed in an immunocompetent person. A 28-year-old female, who had lived in Phoenix, Arizona, USA for 2 years, was admitted for an evaluation of persistent cough with fever lasting for 2 weeks. The chest X-ray and Chest CT revealed multifocal patchy consolidation and ground-glass opacity in both lungs as well as multiple enlarged right hilar and paratracheal lymph nodes. A percutaneous needLe biopsy of the main mass-like consolidation confirmed mature spherules of Coccidioides immitis in lung tissue. Pulmonary coccidioidomycosis should be considered in patients presenting with persistent cough with fever and a history of travel to or immigration from an endemic area.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.49 no.1
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• pp.73-77
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• 2012

In this article, we designed a wide bandpass filter in order to apply microwave reflectometry for KSTAR. The proposed wide bandpass filter consists of a metamaterial structure which is to get a wide band, a lower insertion loss, and a high skirt. This is applied to VCO's output to enhance the linearity. A pass band is 18-28 GHz and the out of pass band is stopped over 20 dB. To confirm of the metamaterial, we suggest a dispersion diagram. The proposed filter in lower band and upper band of pass band is respectively a left handed and right handed characteristics. A group delay is below 0.5 ns.

• Progress in Medical Physics
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• v.24 no.3
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• pp.183-190
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• 2013

Recently, the photoacoustic imaging system has been widely and intensively developed, and has been shown the possibility of diagnosis for early stage cancer. In this study, we developed a photoacoustic tomography imaging system with a commercial ultra sound device and a linear array probe. A tube phantom and a chicken breast phantom was made for the possibility of a system as a breast cancer detection. A moving average filter and a band pass filter with 3~6 MHz bandwidth were developed for background noise elimination before delay-and-sum beamforming algorithm was used for image reconstruction. As a result, we showed that some signal processing procedure before beamforming was effective for the photoacoustic image reconstruction.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.39 no.5
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• pp.391-395
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• 2015

A 15-Lead ECG has been developed to diagnose posterior wall diseases of the heart that a 12-Lead ECG cannot diagnose. However, 15-Lead ECG data for developing heart-diseases-detecting algorithm are limited, and previous ECG simulators cannot predict the ECG waveform according to the changes in electrode. To solve these problems, the lumped parameter model (LPM), which divides the heart into 15 sections with varying electrical capacitance and electrical resistance. To imitate the electrical conduction in the heart, each node was connected to a current source and delivered the specific current considering the positions and time delay. The purpose of this study is to acquire the waveform that can be used in an ECG by delivering the specific current to LPM.

• Proceedings of the Korea Water Resources Association Conference
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• 2016.05a
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• pp.322-322
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• 2016

국내 1, 2종 댐 시설물은 "시설물의 안전관리에 관한 특별법(이하 시특법)" 제7조에 의해 주기적으로 정밀안전진단을 실시하여 상태평가 및 안전성평가에 의한 종합평가 등급을 부여하고 있다. 정밀안전진단 중 안전성 평가의 수문학적 안전성 평가는 댐의 구조형식과 현장진단 결과에 의한 댐의 상태평가에 따라 1차적으로 수행된다. 여유고 부족 또는 월류 발생 등의 1차적인 조건을 만족시키지 못할 경우 그에 따른 댐체의 구조적 안전을 검토(콘크리트댐)하고, 최종적으로 댐 붕괴 발생 시 하류에 미치는 인적, 경제적 위험요인 등을 기준으로 평가하는 3단계 평가가 수행된다. 본 논문에서는 위 단계적 평가가 수행된 기존댐의 수문학적 안전성 평가 및 상태평가 결과를 사용하여, 1종 기존댐에 대한 수문학적 안전성 취약 순위를 선정하고자 한다. 취약 순위를 선정하기 위하여 다기준의사결정기법(Multi-Criteria Decision Making: 이하 MCDM)을 적용하였고, MC DM의 Payoff Matrix 설정을 위하여 수문학적 안전성 평가 지표를 기준으로 설정하였으며, 이 외의 기준으로는 대상 댐의 연최대 강수량 값을 사용하였다. 연최대강수량값을 산정하기 위하여 기상관측소별 연최대 강수량 30년치의 평균값을 kriging 기법에 적용하여 대상댐에 대한 연최대강수량 값을 도출하여 수문학적 안전성 평가 지표 및 기존댐의 기상 관측값에 따른 댐별 수문학적 안전성 취약 순위 선정에 관한 연구를 수행하였다. 위 결과를 활용하여 수문학적 안전성 평가등급에 대한 검토 및 기후변화 적응 댐 수문학적 안전성 평가 프레임워크 개발을 위한 기초 자료로 활용될 것으로 기대된다.

• Journal of the Korean Society of Radiology
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• v.84 no.6
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• pp.1257-1265
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• 2023

Cystic fibrosis (CF) is a fatal hereditary disorder that primarily affects Caucasians and is rare in Asian populations, including Koreans. Diagnosing CF is often challenging and delayed owing to its rarity and its overlapping features with non-CF diseases, ultimately affecting the patient prognosis. Radiologists can provide initial clues for clinically unsuspected cases and play a crucial role in establishing an early childhood diagnosis. This pictorial essay reviews the clinical and imaging features of genetically confirmed CF in Korean children and increases awareness of this rare disease, thereby facilitating early diagnosis.