• Title/Summary/Keyword: 직접주사

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RESEARCH ON SPACE ENVIRONMENTAL EFFECT OF ORGANIC COMPOSITE MATERIALS FOR THERMAL MANAGEMENT OF SATELLITES USING MC-50 CYCLOTRON (MC-50 싸이클로트론을 이용한 위성용 열조절 유기복합재료의 우주환경 영향 연구)

  • Kim, Dae-Weon;Kim, Dong-Iel;Huh, Yong-Hak;Yang, Tae-Keun;Lee, Ho-Young;Kim, Yong-Hyup
    • Journal of Astronomy and Space Sciences
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    • v.22 no.4
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    • pp.441-450
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    • 2005
  • The organic material is one of the most popular material for the satellites and the spacecrafts in order to perform the thermal management, and to protect direct exposure from the space environment. The present paper observes material property changes of organic material under the space environment by using ground facilities. One of the representative organic thermal management material of satellites, 2 mil ITO(Indium Tin Oxide) coated aluminized KAPTON was selected for experiments. In order to investigate the single parametric effect of protons in space environment, MC-50 cyclotron system in KIRAMS(Korea Institute of Radiological and Medical Science) was utilized for the ion beam irradiation of protons and ion beam dose was set to the Very Large August 1972 EVENT model, the highest protons occurrence near the earth orbit in history. The energy of ion beam is fixed to 30MeV(mesa electron volt), observed average energy, and the equivalent irradiance time conditions were set to 1-year, 3-year, 5-year and 10-year exposure in space. The procedure of analyses includes the measurement of the ultimate tensile strength for the assessment of quantitative degradation in material properties, and the imaging analyses of crystalline transformation and damages on the exposed surface by FE-SEM(Field Emission Scanning Electron Spectroscopy) etc.

Improving Oxygenation in the Murine Tumors by a perfluorochemical Emulsion (Fluosl-DA $20\%$ (Carbogen 흡입하에서 Fluosol-DA 20%의 투여가 이식동물 종양의 산소분압에 미치는 영향)

  • Lee Intae;Kim Gwi E.;Song Chang W.
    • Radiation Oncology Journal
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    • v.8 no.1
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    • pp.1-6
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    • 1990
  • In the present study, a perfluorchemical emulsion (Fluosol-DA $20\%$) did not alter $D_o\;and\;D_q$ values on cell survival curve, indicating that the lack of a direct effect of Fluosol-DA $20\%$ on cellular radiosensitivity in vitro. The effect of Fluosol-DA $20\%$ injection in combination with carbogen breathing was determined on the hypoxic cell fraction in SCK tumors. The hypoxic cell fraction in control SCK tumors was 0.39. This value decreased to 0.05 when the mice were i.v. injected with 12 ml/kg of Fluosol-DA $20\%$ in a carbogen atomosphere. The measured mean and median $PO_2$ values with a microelectrode in the control tumors was 9 mmHg and 4 mmHg, respectively. The treatment of the SCK tumors in the host mice with injected Fluosol-DA $20\%$ in combination with carbogen breathing increased the mean and median $PO_2$ values to 67 mmHg and 62 mmHg, respectively. Using carbogen breathing alone caused a moderate increase of tumor $PO_2$. But Fluosol-DA $20\%$ injection alone caused little change $PO_2$ in the tumor. It was concluded that the combination of Fluosol-DA injection and carbogen breathing is an effective means to improve oxygenation of tumors.

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Effect of Process Parameters on Quality in Joint for Al/Steel Joining a MPW (전자기 펄스 용접을 이용한 Al/Steel 접합시 접합부 품질에 미치는 공정변수 영향)

  • Shim, Ji-Yeon;Kang, Bong-Yong;Kim, Ill-Soo;Park, Dong-Hwan;Kim, In-Ju;Lee, Kwang-Jin
    • Proceedings of the KWS Conference
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    • 2009.11a
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    • pp.27-27
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    • 2009
  • 드라이브 샤프트는 일반적으로 엔진에서 발생된 회전력을 바퀴에 직접 전달하는 동시에 조향기능을 수행하는 자동차 부품이다. 최근에 경량화를 통한 에너지 절감을 위하여 기존 스틸소재를 알루미늄으로 대체하는 방안에 대한 연구가 집중되고 있다. 그러나 알루미늄 단일소재로 드라이브 샤프트를 제조하는 것은 비경제적이며 또한 기 개발된 자동차 부품들과의 연결을 고려하여 알루미늄 튜브와 스틸 요크의 이종금속 접합기술이 요구된다. 전자기 펄스용접은 전자기력을 이용하여 용접대상물을 고속으로 충돌시켜 용접하는 기술로서 열 발생이 적어 재료의 특성차로 인한 결함 및 변형이 발생하지 않아, 이종금속간 고품질 용접이 가능하며, 전자기 펄스 용접부의 품질과 밀접한 관계를 갖는 공정변수 경우 모재와 접합재의 재질 따라 적정 공정변수 범위가 변화되므로 공정에 따른 데이터의 축적은 대단히 중요하다. 전자기 펄스 용접을 이용한 이종금속 접합시 접합부 품질에 영향을 미치는 공정변수는 충전전압, 모재와 접합재 사이의 간격 및 접합재의 직경과 두께의 비(D/T비)로서 보고되었으며, Al/Steel 이종 금속 접합시 이들 공정변수가 접합부에 미치는 영향 및 최적의 공정변수 도출을 위한 연구는 시도되지 않았다. 따라서 본 연구는 전자기 펄스 용접기술을 이용한 Al/Steel 이종금속 접합 실험을 통하여 전자기 펄스용접의 적정성과 최적의 충전전압, 모재와 접합재 사이의 간격, D/T비를 도출하고자 한다. 전자기 펄스 용접 장치는 한국생산기술연구원과 웰메이트(주)에서 공동으로 개발한 $120{\mu}F$의 캐패시터 6개로 구성된 'W-MPW36'을 사용하였으며 이 장치의 최대충전전압과 최대접합용량은 각각 10kV, 36kJ이다. 접합재는 전기 전도율의 높은 Al 1070 파이프를 사용하였으며 모재는 기존 스틸 요크재인 SM45C 환봉을 사용하였다. 기보고된 연구를 통하여 코일과 접합재 사이의 간격이 좁을수록 높은 전자기력이 접합재에 작용하는 것을 확인하였으나 코일내 접합재와 모재 삽입 편의를 위하여 1mm로 설정하였다. 접합부의 품질 평가를 위하여 수압시험을 실시하였으며, 시험 후 접합부 단면을 주사전자현미경(SEM)을 이용하여 관찰하였다.

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Effect of anticancer drug methortrexate on the biliary excretion kinetics of the reudced folate derivatives in rats (항암제 methotrexate가 랫드 담즙중 환원형엽산유도체의 배설동태에 미치는 영향)

  • Shin, Ho-chul;Cha, Shin-woo;Bae, Ju-hyun;Kim, Hyun-ju;Jeong, Tae-cheon;Park, Jong-il;Yoon, Jong-man;Kim, Gye-woong;Kim, Jin-suk;Han, Sang-seop
    • Korean Journal of Veterinary Research
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    • v.36 no.1
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    • pp.57-63
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    • 1996
  • The biliary excretion kinetics of the active folate derivatives were examined after an intravenous injection of methotrexate at doses of 0.3 and 10mg/kg to clarify the mechanism of the acute decrease in the plasma folate by the dihydrofolate reductase inhibitors. Even at a higher dose than used in the clinical therapy, methotrexate did not cause any acute depletion of folate denvatives in the excreted bile. Therefore, the decrease in the plasma folate appeared not to be related with the biliary excretion process of folates. A factor responsible for the plasma folate depletion by DHFR inhibitors may be due to the malabsorption of folate derivatives excreted into the small intestine.

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Engineering Properties of Uncemented Mudrock from Yeoju Area, Gyeonggi-Do (경기도 여주지역 미고결 이암의 공학적 특성)

  • Ban, Hoki;Lee, Huiyoun;Bae, Kyujin;Cho, Wanjei
    • Journal of the Korean GEO-environmental Society
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    • v.16 no.12
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    • pp.53-58
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    • 2015
  • Engineers should take great care of characterizing the engineering properties of mudrock, because the uncemented mudrock can be considered as a hard rock in appearance. Therefore, the mudrock samples obtained from the cut slope in Gyeongki-do were tested to evaluate the strength characteristics of uncemented mudrock in this study. The performed tests are index properties, slake durability, and swelling tests for the classification of the mudrock for engineering practice. To evaluate the effect of water on the engineering properties of the uncemented mudrock, resonant column, triaxial compression and direct shear tests with various water contents were performed. With the increasing water contents, stiffness at very small to small strain region and the cohesion value of the strength parameters decrease. Based on the test results, engineers should take great care of evaluating the engineering properties of uncemented mudrock.

Osteoarthritis of the Temporomandibular Joint (측두하악관절의 골관절염)

  • Lee, Jeong-Yun
    • Journal of Oral Medicine and Pain
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    • v.38 no.1
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    • pp.87-95
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    • 2013
  • Osteoarthritis (OA) of the temporomandibular joint (TMJ) is a severe form of temporomandibular disorders (TMDs), presenting gradual breakdown of articular cartilage and subchondral bone by the functional load sustained to exceed the physiologic tolerance of the joint. In such a joint loaded, offensive bioactive materials such as matrix degrading proteins, cytokines, and free radicals increase in concentration to shift the tissue response in the joint to degeneration from regeneration or remodeling. Recently, it has been issued that obesity can play an offensive role in pathogenesis of OA in a metabolic way. Adipokines released by adipose cells are present at higher concentration in the arthritic joint and joints of obese individuals. However, because of conflicting data reported, further scientific study should be performed to elucidate the practical role of adipokines in pathogenesis of TMJ OA. As far as the clinical signs and symptoms of TMJ OA are not much different from those of other forms of TMD and any definitive treatment modality to control directly the bone resorptive activity is not available yet, the treatment of TMJ OA should be directed to reduce the physical load and enhance the physiologic tolerance of the joint by means of conservative treatment such as physical therapy, medication, and occlusal splint therapy for sufficient period and, if needed after that, supplementary surgical procedure such as intra-articular injection, arthrocenthesis, and arthroscopic surgery that have turned out to be effective to control OA signs and symtpoms. Enthusiastic reassurance and motivation for patients to control behaviors for themselves to reduce unnecessary functional load in daily life is very important for the joint to reach to more favorable orthopedic stability of the TMJ more quickly, guaranteeing more successful management TMJ OA.

Characterization of immobilized laccase and its catalytic activities (고정된 laccase의 특성 및 촉매효과)

  • Hyung Kyung Hee;Shin Woonsup
    • Journal of the Korean Electrochemical Society
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    • v.2 no.1
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    • pp.31-37
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    • 1999
  • Copper-containig enzyme, laccase (Rhus vernicifera) was immobilized onto gold electrode using self-assembly technique and its surface properties and catalytic activities were examined. Laccase is an oxidoreductase capable to oxidize diphenols or diamines by 4-electron reduction of molecular oxygen without superoxide or peroxide intermediates. The electrode surface were modified by $\beta-mercaptopropionate$ to have a net negative charge in neutral solution and positively charged laccase (pI=9) was immobilized by electrostatic interaction. The successful immobilization was confirmed by cyclic voltammograms which showed typical surface-confined shapes and behaviors. The amount of charge to reduce the surface was similar to the charge calculated assuming the surface being covered by monolayer. The activity of the immobilized enzyme was tested by the capbility of oxidizing a substrate, ABTS (2,2-azine-bis-(3-ethylbenzthioline-6-sulfonic acid) and it was maintained for $2\~3$ days at $4^{\circ}C$. The immobilzed laccase showed about $10\~15\%$ activity compared to that in solution. The laccase-modified electrode showed the activity of elefoocatalytic reduction of oxygen in the presence of mediator, $Fe(CN)_6^{3-}$ The addtion of azide which is an inhibitor of laccase compeletly eliminated the catalytic current.

Superconductivity of High $T_c$ Superconductor $(Y_{1-x}Eu_x)Ba_2Cu_3O_{7-{\delta}}$ (고온초전도체 $(Y_{1-x}Eu_x)Ba_2Cu_3O_{7-{\delta}}$의 초전도성)

  • Chung Won Yang;Kweon Jung Ohk;Cho Eun Kyung;Kim Keyung Nam;Han, Sang Mok
    • Journal of the Korean Chemical Society
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    • v.36 no.1
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    • pp.16-23
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    • 1992
  • High $T_c$, superconductor $(Y_{1-x}Eu_x)Ba_2Cu_3O_{7-{\delta}}$ (x = 0.0, 0.2, 0.4, 0.6, 0.8, 1.0) were prepared and the physical properties were observed. XRD analysis showed that the structures of all the specimen were orthorhombic and the lattice parameters a, b and c increased with the increasing x value. Electrical resistivity and magnetization measurements revealed that pure high $T_c$, superconducting phases were formed at above 90 K. The critical temperatures increased with increasing the amount of Eu. From the measurement of magnetization and the size of the grains using SEM micrographs, volume diamagnetic susceptibilities for each specimen were calculated. These values decreased with the increasing x value. The composition of Ba in the lattice site decreased as the concentration of Eu increased, and this was confirmed by EPMA. It was found out that the volume diamagnetic susceptibility of each specimen was directly influenced by the composition of Ba in the lattice site.

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Preparation and Flame Retardancy of Poly(benzoxazole imide) Having Trifluoromethyl Group in the Main Chain (주사슬에 Trifluoromethyl 그룹을 갖는 Poly(benzoxazole imide)의 제조 및 난연 특성)

  • Yeom, Jin-Seok;Choi, Jae-Kon;Lee, Chang-Hoon
    • Elastomers and Composites
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    • v.47 no.4
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    • pp.355-363
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    • 2012
  • A series of poly(hydroxyamide)s (PHAs) having trifluoromethyl group were prepared by direct polycondensation of aromatic diimide-dicarboxylic acids with 2,2-bis(3-amino-4-hydroxyphenyl)hexafluoropropane by thionyl chloride and triethyl amine in N-methyl-2-pyrrolidinone (NMP). The PHAs exhibited inherent viscosity in the range of 0.54-0.96 dL/g at $35^{\circ}C$ in DMAc solution. All PHAs were readily soluble in a variety of organic solvents, whereas the polybenzoxazoles (PBOs) were quite insoluble except partially soluble in sulfuric acid. PHAs were converted to PBOs by thermal cycling reaction with heat of endotherm. The maximum weight loss temperature of the PHAs occurred in the range of $559-567^{\circ}C$. The PBOs showed relatively high char yields in the range of 47-59%. Pyrolysis Combustion Flow Calorimeter (PCFC) results of the PBOs showed 12-19 W/g heat release rate (HRR), and 2.7-3.6 kJ/g total heat release (total HR). The HRR of PBO 1 showed the lowest value of 12 W/g, which was 37% lower than that of PBO 3 (19 W/g).

Characterization of Composite Membranes Made from Sulfonated Poly(arylene ether sulfone) and Vermiculite with High Cation Exchange Capacity for DMFC Applications (높은 이온교환능력을 가지는 버미큘라이트와 술폰화된 폴리아릴렌에테르술폰으로 제조된 복합막의 연료전지 적용을 위한 특성평가)

  • Kim, Deuk-Ju;Hwang, Hae-Young;Nam, Sang-Yong
    • Membrane Journal
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    • v.21 no.4
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    • pp.389-397
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    • 2011
  • In this study, polymer composite membranes based on sulfonated poly(arylene ether sulfone) (SPAES) were prepared using a solution casting method with different amount of vermiculite (VMT) content. The dispersion of VMT particles in the SPAES matrix was confirmed by means of a scanning electron microscopy observation. The composite membrane containing less than 1 wt% of VMT has a smooth skin on the top and bottom, which means there is a good dispersion of VMT in the matrix. The water uptake of the composite membranes gradually increases as the temperature increases, and the results confirm that all the adsorbed water is bound water because VMT has a strong water affinity on account of its high cation exchange value. A composite membrane with a VMT content of less than 1 wt% increases the proton conductivity and reduces the methanol permeability. Of all the composite membranes, the membrane SPAES/VMT 1.0 has the best fuel cell performance in terms of membrane selectivity. The performance value of SPAES/VMT 1.0 is double that of Nafion 112, which suggests that SPAES/VMT1.0 could be an excellent candidate for direct methanol fuel cells.