• Title/Summary/Keyword: 지질성분

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Hypoglycemic and antioxidant effects of jaceosidin in streptozotocin-induced diabetic mice (Jaceosidin이 streptozotocin으로 유도된 당뇨 쥐의 혈당강하 및 항산화능에 미치는 영향)

  • Park, Eunkyo;Kwon, Byoung-Mog;Jung, In-Kyung;Kim, Jung-Hyun
    • Journal of Nutrition and Health
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    • v.47 no.5
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    • pp.313-320
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    • 2014
  • Purpose: In this study, we investigated the effects of jaceosidin on blood glucose regulation in type 1 diabetic mice. Methods: C57BL/6 mice were divided into four groups; normal control (Normal), diabetes control (D-Control), diabetes low-jaceosidin (D-0.005%), and diabetes high-jaceosidin (D-0.02%). Type 1 diabetes was induced by streptozotocin and mice were then fed a diet containing jaceosidin for eight weeks. Fasting blood glucose, oral glucose tolerance test, insulin tolerance test, lipid peroxidation, and antioxidant enzyme activities were assessed. Results: Jaceosidin supplementation for eight weeks had no effect on body weight, organ weight, and blood lipid profiles. However, jaceosidin supplementation significantly lowered fasting blood glucose level and reduced insulin resistance. We also found that jaceosidin supplementation increased antioxidant capacity by enhancement of catalase and GSH-px activities. Conclusion: These results suggest that jaceosidin could be a therapeutic candidate to ameliorate hyperglycemia through increase of antioxidant enzyme activity.

Inhibition Effects of Zanthoxylum schinifolium and Its Active Principle on Lipid Peroxidation and Liver Damage in Carbon Tetrachloride-treated Mice (산초 및 그 활성성분이 사염화탄소를 부여한 Mouse에 있어서 지질과산화 및 간손상 억제에 미치는 영향)

  • 문숙임;류홍수;최재수
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.26 no.5
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    • pp.943-951
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    • 1997
  • The present study was undertaken to investigate the inhibition effects of sancho(Zanthoxylum schinifolium) on lipid peroxidation and liver damage in carbon tetrachloride tetracloride-treated mice. Mice aged 3 weeks old were fed diets containing either dry sancho powder, methanol extract or hyperoside isolated from sancho at the various levels for 2 weeks(sancho, methanol extract from sancho) or 3 days (hyperoside) before $CCl_{4}$ treatments. Seed coats of sancho added to diet with the levels from 1.25 to 5.0% significantly reduced(p<0.001) thiobarbituric acid reactive substances(TBARS) formation in liver and serum of mice treated with carbon tetrachloride. $CCl_{4}$ treatments significantly increased (p<0.001) in liver TBARS comparing with those of the untreated control, while methanol extract from the seed coat of sancho added to diet with the levels from 0.5 to 1.0% significantly reduced (p<0.01) to 20mg per kg of body weight showed significant reduction(p<0.01, p<0.001) of liver TBARS in mice treated with $CCl_{4}$. $CCl_{4}$ treatments significantly increased(p<0.05) in serum TBARS comparing with those the levels from 0.5 to 1.0% significantly reduced(p<0.01) serum TBARS in mice treated with $CCl_{4}$, and administration of hyperoside with the levels from 10 to 20mg per kg of body weight showed significant reduction(p<0.01, p<0.001) of serum TBARS in mice treated with $CCl_{4}$. $CCl_{4}$ significantly increased(p<0.001) in serum AST activities comparing with those of the untreated control, while either addition(0.5, 1.0%) of methanol extract from sancho or administration(10, 20mg/kg) of hyperoside significantly reduced(p<0.001, p<0.05) serum AST activities in $CCl_{4}$-treated mice. $CCl_{4}$ treatments showed significant increases(p<0.001) in serum ALT activities comparing with those of the untreated control, while either addition(0.5, 1.0%) of methanol extract from sancho or administration (10, 20mg/kg) of hyperoside showed moderate decreases(p<0.01, p<0.001) serum ALT activities in $CCl_{4}$-treated mice.

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Optimum Stocking Density of Juvenile Abalone (Haliotis discus hannai) Fed the formulated Diet or Macroalgae (Undaria) (실험 배합사료 및 미역 공급시 참전복 치패의 적정 사육밀도)

  • KIM Byong-Hak;LEE Sang-Min;GO Chang-Soon;KIM Jae-Woo;MYEONG Jeong-In
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.31 no.6
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    • pp.869-874
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    • 1998
  • A feeding trial was carried out to investigate the optimum density of juvenile abalone (Haliotis discus hannai) fed the formulated diet or macroalgae ( Undaria). Abalone with initial average shell length of 8.41 mm were stocked into three replicate tanks at four different densities of 1430, 2860, 4290, and 5720 individual/$m^2$ for 15 weeks. The formulated diet produced higher body weight and shell growth, soft body weight and survival rate than Undaria in abalone. Abalone fed the formulated diet have significantly (P<0,05) higher lipid and ash, and lower moisture and protein in soft body. Higher density resulted in lower growth and survival (P<0.05). Whereas shell growth, survival rate and weight gain were not significantly (P>0.05) different within the abalone stocked at stocking densities of 1430 and 2860 individual/$m^2$ in each diet group. Body composition of abalone was not affected by increasing density. These study indicate that the number of abalone (shell length ranges of between 8 mm and 17 mm) below 2860 individual/$m^2$ were predicted to effective density in the indoor tank culture system.

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The Effect of Nutrition Education and Excercise Program on Body Composition and Dietary Intakes, Blood Lipid and Physical Fitness in Obese Women (2) - Relationship between Participation Rates and Effectiveness of Obesity Management Program - (영양교육과 운동중재 프로그램이 성인비만여성의 신체성분과 식이섭취, 혈중지질 및 기초체력에 미치는 효과 (2) - 비만관리 프로그램의 참여율과 프로그램 효과와의 상관성 -)

  • Lee, Hee-Seung;Lee, Ji-Won;Kim, Ji-Myung;Chang, Nam-Soo
    • Journal of Nutrition and Health
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    • v.43 no.3
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    • pp.260-272
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    • 2010
  • This study examined how the participation rates contribute to subjects' outcomes after a nutrition education (once/week) and exercise (3 times/week) intervention program for 12 weeks in 44 obese female subjects. The subjects were divided into two groups: high-participator (HP) or low-participator (LP) groups according to their participation levels based on the median visit value (30 visits out of a total of 48 visits). Daily nutrient intakes assessed by a 24-hour recall, body composition, blood lipid profiles and physical fitness were measured at baseline and after 12 weeks. After the intervention, weight, BMI, percent body fat, and the waist-hip ratio were significantly decreased in the HP group. In addition, the HP group had a greater rates of changes in weight (HP group: -6.6% and LP group: -3.1%, p < 0.01), BMI (-7.0% and -3.2%, p < 0.01), percent body fat (-7.8% and -4.2%, p < 0.05), and waist-hip ratio (-3.1% and -0.4%, p < 0.01) compared to the LP group. Energy-adjusted protein, fiber, potassium, vitamin $B_1$, vitamin $B_6$, and vitamin C were significantly increased in the HP group. The HP group showed a significant increase in HDLcholesterol and a decrease in blood pressure, total cholesterol, LDL-cholesterol, triglycerides, and atherogenic index (AI). While the muscle endurance, muscle strength, power, agility and flexibility were significantly increased in the HP group, agility and balance were improved in the LP group. In addition, dietary behavior score was significantly increased and stress score decreased in the HP group compared to the LP group. High participation rates were correlated with the improvement of the nutrient density (protein, fiber, potassium, Vitamin $B_1$, Vitamin $B_2$, Vitamin $B_6$ and folate), anthropometric parameters (body weight, BMI and percent body fat), serum lipid profiles (HDL-cholesterol, Triglyceride, and AI) and physical fitness (muscle endurance) adjusted for age, menopausal status, alcohol drinking, nutritional supplement use and baseline BMI. Our results suggest that high participation in nutrition education and exercise program was effective not only for weight reduction but also for the improvement of physical fitness in obese women.

Antioxidant activities, production of reactive oxygen species, and cytotoxic properties of fractions from aerial parts of glasswort (Salicornia herbacea L.) (퉁퉁마디 지상부 분획의 산화방지 활성, 활성산소종 생성과 세포독성 조절작용)

  • Kang, Smee;Hong, Jungil
    • Korean Journal of Food Science and Technology
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    • v.48 no.6
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    • pp.574-581
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    • 2016
  • Glasswort (Salicornia herbacea L.) is an edible halophyte that grows in salt marshes. In the present study, anti- and pro-oxidant activities and cytotoxic properties of glasswort were investigated. Solvent fractions, including fractions of hexane, ethylether (Fr.E), ethylacetate (Fr.EA), butanol and water, were prepared from a 70% methanol extract of glasswort aerial parts. Fr.EA contained the highest levels of total polyphenols and flavonoids, showing the strongest scavenging activities against DPPH and ABTS radicals, and nitrite. In addition Fr.EA showed the most potent cytotoxic effects on HCT-116 colon cancer cells and INT-407 normal intestinal cells, followed by Fr.E. Most fractions also decreased the level of reactive oxygen species in the treated cells, but generated $H_2O_2$ in the medium. The cytotoxic activity of Fr.EA was more pronounced in the presence of ascorbic acid or N-acetylcysteine. These results indicate that the fractions from aerial parts of glasswort exhibit both anti- and pro-oxidant activities, and these activities modulate cytotoxic properties.

Processing and quality stability of precooked frozen fish foods : (I) Processing of sardine burger (조리냉동식품의 가공 및 저장중 품질안정성 : (I) 정어리버어거의 가공)

  • Ihm, Chi-Won;Kim, Jin-Soo;Joo, Dong-Sik;Lee, Eung-Ho
    • Applied Biological Chemistry
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    • v.35 no.4
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    • pp.254-259
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    • 1992
  • The processing conditions and food components of meaty textured sardine burgers were studied to develope a new form of burger, The separated sardine meat was chopped, mixed with 14.1% emulsion curd, 1.5% table salt, 2.0% sugar, 0.4% sodium bicarbonate, 0.2% polyphosphate, 0.1% monosodium glutamate, 8.0% bread powder, 0.4% onion powder, 0.1% garlic powder, 0.1% ginger powder and 3.0% soybean protein by remodeled stone mortar. This seasoned sardine meat was fried in soybean oil $(165{\pm}2^{\circ}C,\;3min)$. The main fatty acids of sardine burger were palmitic acid, oletic, acid, linoleic acid, eicosapentaenoic acid and docosahexaenoic acid. Amino acid composition of sardine burger were mainly consisted of histidine, glutamic acid, leucine and lysine. The major taste compounds in the product were revealed nucleotides and their related compounds $(11.19{\sim}11.96\;{\mu}mole/g)$ such as IMP and free amino acids (1824.8 mg/100g) such as histidine, glutamic acid, leucine and lysine. Total creatinine, betaine and trimethylamine oxide were seemed to act an auxiliary role in taste of product.

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Variations of Mechanical Properties of Hallasan Trachyte with respect to the Degree of Weathering (풍화진행에 따른 한라산조면암의 역학적 특성변화)

  • Cho, Tae-Chin;Lee, Sang-Bae;Hwang, Taik-Jean;Won, Kyung-Sik
    • Tunnel and Underground Space
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    • v.19 no.4
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    • pp.287-303
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    • 2009
  • Rock mass in Baekrokdam at the summit of Hallasan in Jeju island is composed of two volcanic rock types: Baekrokdam trachybasalt at the eastern region and Hallasan trachyte at the western region. On-going rockfall and subsequent collapse of Baekrokdam wall rock are closely linked to the weathering of trachyte distributed in the western region of Baekrokdam. Samples of Hallasan trachyte showing different weathering grades had been collected and the polarizing microscopic observation, X-ray diffraction analysis and analysis for chemical weathering had been conducted. Formation of secondary minerals, especially clay minerals, by chemical weathering has not been identified, but the change of chemical weathering indices indicated that chemical weathering process had been proceeded to the degree for increasing and decreasing the contents of some chemical components. Changes in physical and mechanical rock properties due to weathering has also been examined. Artificial weathering test of freezing-thawing reveals that the process of crack initiation and propagation deteriorated the mechanical characteristics of Hallasan trachyte and $D_B$ = 1.5 or porosity = $20{\sim}21%$ would be the ultimate limiting value induced by the mechanical weathering processes.

Investigation on Agricultural Land Use and Soil Characteristics along Bonghwang-cheon Watershed in Milyang (밀양 봉황천 수계지역의 토지이용현황과 토양특성)

  • Lim, Dong-Kyu;Kang, Hang-Won;Jung, Yeun-Tae;Park, Kyeong-Bae;Park, Moo-Eon
    • Korean Journal of Soil Science and Fertilizer
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    • v.30 no.3
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    • pp.280-287
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    • 1997
  • This study was carried out to investigate agricultural status and soil fertility of Bonghwang-cheon watershed area which is located at Chodong-myeon, Milyang-si. The acreage of arable land was about 1,209ha, and the population was 3,706 people. Out of total arable land, paddy was 64.4%, upland 19.6% and orchard 16.0%. Chicken was the largest in the number of livestock and poultry, but pig seems to contribute most severly to water pollution. The geology in the lower stream was alluvium but andesite and derivated materials from it were occupied most upland areas. Tuff was scattered in the small area near by the alluvium of Nakdong river, and diorite and granodiorite were located at the low hill and mountains respectivately. The principal paddy soils in the area were Geumgog, Jisan and Imgog series etc of fine loamy on sloped valleys and fans. The Pyeongtaeg series, fine silty family of imperfectly drained on plain was irrigated by Chodong reservoir. The clayey Honam series on alluvium was distributed along the low hill while Gyuam series, coarse silty alluvial soil way close to Nakdong river. In chemical properties of soils, the vinyl house soils were higher in EC, and orchard soils in OM, $P_2O_5$, exchangeable canons than other soils.

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Studies on Biological Activity of Wood Extractives(IV) - Antimicrobial and Antioxidative Activities of Extractives from the Heartwood of Morns bombycis and Synthesized Congeneric Stilbenoids - (수목추출물의 생리활성에 관한 연구(IV) - 산뽕나무 심재 추출성분과 유연 합성 stilbenoid의 항균 및 항산화활성 -)

  • Lee, Sung-Suk;Lee, Hak-Ju;Choi, Don-Ha;Hishiyama, Shojiro;Kato, Atsushi
    • Journal of the Korean Wood Science and Technology
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    • v.28 no.3
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    • pp.70-77
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    • 2000
  • Among four compounds such as oxyresveratrol, resveratrol, morin and afzelechin isolated from the heartwood of Morns bombycis, oxyresveratrol and resveratrol which belong to stilbenoid indicated high antioxidative and antimicrobial activity, respectively. Based on this result, this experiment was carried out to elucidate the relationship between biological activities of stilbenoids and their chemical structures using two isolated and six synthesized ones prepared by Wittig reaction. Antimicrobial activity of 3,5-dihydroxystilbene(pinosylvin) devoid of hydroxyl group of B-ring was the best among the tested stilbenoids. Antimicrobial activities of the stilbenoids showed negative dependency on the number of hydroxyl groups of B-ring, that is, the fewer number of hydroxyl groups of B-ring, the higher antimicrobial activity. On the other hand, antioxidative activities of the stilbenoids indicated a positive relationship with the number of hydroxyl groups of B-ring. In tetrahydroxystilbenoids, antioxidative activities of the compounds possessing ortho-diphenol structure, 2',3,3',5- and 3,3',4',5-tetrahydroxystilbene, were superior to the others. As a result, it was concluded that resveratrol and oxyresveratrol isolated from the heartwood of M. bombycis had antimicrobial and high antioxidative activities, and these activities of stilbenoids were also dependent on the number and position of hydroxyl groups of B-ring.

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Criteria and Index of Social and Economic Evaluation in River Restoration (하천복원사업의 사회.경제성 평가 기준 및 지표에 관한 연구)

  • Kim, Chong-Won;Yi, Jung-Hun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.470-474
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    • 2007
  • 본 논문에서는 하천복원사업으로부터 발생하는 사회 경제적 편익의 측정 및 평가를 위한 기준 및 지표를 다루고자 한다. 하천복원사업의 목적 및 하천의 기능 및 사업의 영향을 기초로 선정된 평가 기준은 크게 생태적 측면과 사회 경제적 측면으로 나눌 수 있다. 본 연구에서 생태적 측면이 강조되는 것은 하천 생태의 다양한 측면을 파악하는 것이 사회 경제성 연구에 있어 풍부한 논의의 가능성을 제공해주는 측면이 있기 때문이다. 이는 하천복원사업이 가지는 복합적인 성격으로 인해 사업의 사회적, 경제적, 생태적 영향이 서로 고립되지 않고 영향을 주고받는 것에서 연유한다. 첫 번째 평가 기준인 생태적 측면에서는 세부기준으로 생태계 및 수문부문 등의 변화를 포함하며, 복원사업 전후의 서식처 및 생물 종 다양성의 변화, 하상의 다양화 등을 지표로 고려할 수 있다. 나머지 큰 평가 기준인 사회 경제적 측면에서는 홍수방지 효과나 수질개선 효과와 같은 우리가 생태계로부터 제공받는 직접적인 서비스나 토지 이용의 변화 및 그 변화에서 야기되는 영향(하천의 친수 기능이나 학습효과 등), 복원사업의 관리 및 비용 측면 등을 세부기준으로 고려할 수 있다. 하천복원사업의 구체적인 평가를 위해, 각 세부기준에 대한 지표는 현 복원사업에서 실시되는 평가기법, 하천복원관련 문헌조사 및 사례조사를 통해 검토하여 일차적으로 선정한다. 각 지표는 고려하고자 하는 특성에 따라 정량화가 용이한 지표와 정성적 측면이 강한 지표로 나뉜다. 이렇게 선정된 지표는 전문가 조사를 통해 지표에 대한 의견을 수렴하여 확정한다.한 치즈곤죽에서는 쓴맛 펩타이드가 형성되었다가 사라짐을 관찰할수 있었다. 한편 지질분해효소를 침가할 경우 총 휘발성산이 4일 이후에 급격히 증가함을 통해 사용한 효소는 유지방을 잘 분해함을 알 수 있었으며 GLC에 의한 유리 지방산의 분석 결과는 Cheddar치즈곤죽은 시판Cheddar 치즈와 비슷하고 Italian형 치즈곤죽은 시판 Italian치즈보다 약간 떨어졌다. Cheddar치즈의 중요한 품미성분인 활성 SH기는 glutathione을 첨가한 치즈곤죽에서 발효 4일부터 증가하였으며 단백질분해효소를 함께 첨가할 경우 그 증가현상이 현저하였다. 단백질분해요소의 첨가유무에 따라 점도 변화는 다른 두 가지 양상으로 나타나 효소를 첨가할 경우 단백질이 분해됨에 따라 점도가 급격히 감소하였다.>${\pm}0.36$) %, 0.34(${\pm}0.27$) %, 0.34(${\pm}0.18$) % 의 오차를 보였다 중간에 6 cm 의 PP 을 위치한 경우에는 에너지별로 1.15(${\pm}1.86$) %, 0.90(${\pm}1.43$)%, 0.86(${\pm}1.01$)% 의 오차를 나타내었다. 이 경우에는 PCD 10 cm 의 경우에 비교적 큰 오차를 보였으며 PCD 10 cm 인 경우를 제외하면 에너지별로 0.47(${\pm}1.17$) %, 0.42(${\pm}0.96$) %, 0.55(${\pm}0.77$0.

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