• Journal of Yeungnam Medical Science
• /
• v.18 no.2
• /
• pp.253-266
• /
• 2001

Background: The causes of ADHD(attention deficit hyperactivity disorder) are various, so it is impossible to understand the whole characteristics of ADHD, only with simple intelligence testing scales. We compared cognitive characteristics of ADHD group with normal controls with Korean Kaufman Assessment Battery for Children(K-ABC). It is well known to evaluate neuropsychological and cognitive aspects of the children. Materials and Methods: Age and sex matched 40 ADHD patients and 40 normal controls tested with the K-ABC. Each subscales compared between pre-treatment patients and controls, pre-treatment and post-treatment in patient group, post-treatment patients and controls. Results: Significant differences are observed in sequential processing, simultaneous processing, cognitive processing and achievement between pre-treatment patients and controls, and in gestalt closure between pre-treatment and post-treatment patients group. But there are no significant differences between pre-treatment patients and controls in gestalt closure and reading/decoding. Conclusions: Methylphenidate improved the scores of simultaneous scale, which means improvement of executive functions such as divided attention, analysis and organization. Methylphenidate also reduced distractibility.

• Journal of the Korean Society for Library and Information Science
• /
• v.52 no.1
• /
• pp.341-357
• /
• 2018

Due to the paradigm of open science and advanced digital information technology, data sharing and re-use have been actively conducted and considered data-intensive in a wide variety of disciplines. This study aims to investigate the intellectual structure portrayed by the research products re-using the data sets from ICPSR. For the purpose of this study, a total of 570 research products published in 2017 from the ICPSR site were collected and analyzed in two folds. First, the authors and publications of those research products were analyzed in order to show the trends of research using ICPSR data. Authors tend to be affiliated with university or research institute in the United States. The subject areas of journals are recognized into Social Sciences, Health, and Psychology. In addition, a network with clustering analysis was conducted with using co-word occurrence from the titles of the research products. The results show that there are 12 clusters, mental health, tabocco effect, disorder in school, childhood, and adolescence, sexual risk, child injuries, physical activity, violent behavior, survey, family role, women, problem behavior, gender differences in research areas. The structure portrayed by ICPSR data re-uses demonstrates that substantial number of studies in Medicine have been conducted with a perspective of social sciences.

• The Journal of Korea Assosiation for Disability and Oral Health
• /
• v.9 no.1
• /
• pp.42-45
• /
• 2013

De Grouchy syndrome or Distal 18q- is a genetic condition caused by a deletion of genetic material within chromosome 18, and the deletion involves the distal section of 18q. It causes a wide range of medical and developmental concerns. Congenital orthopedic anomalies, cleft lip and palate are relatively common. People with distal 18q- are often small for their age. Most individuals with distal 18q- fall in the mild to moderate range of intellectual disability. Strabismus and nystagmus, changes in the optic nerve as well as colobomas are also fairly common. People with distal 18q- frequently have conductive and/or sensorineural hearing loss. At present, treatment for distal 18q- is only symptomatic. This article presents a case report: Caries treatment of a 4-year-old female patient with de Grouchy syndrome under general anesthesia. The special considerations of dental care, especially caries treatment for the patient with de Grouchy syndrome are discussed.

• The Journal of the Korea Contents Association
• /
• v.14 no.12
• /
• pp.854-862
• /
• 2014

Attention deficit hyperactivity disorder (ADHD) students' intellctual defects, learning problems, and poor academic achievements seem to be due to significantly lower intelligence compared to the normal students, but rather the characteristic of inability to pay attention at a given time can be seen as the more attributing reason. In this study, a comparison between the ADHD students and the normal students will be performed using a fMRI analysis in order to differentiate the brain function between the two groups during a working memory task performance and to assess the difference in the activated regions of the brain. Clinical survey examinations and fMRI measurements were performed for a group of 26 elementary students from the Incheon area. The stimulus of fMRI was a working memory. Cartography statistically analyzed parameters and the Statistical Package of Social Sciences using single-sample t-test, two-sample t-test, were analyzed by multiple regression analysis, the statistical significance level was p<0.05 in, respectively. The disproportionate developments could be seen in the ADHD students group such as the frontal cortex, parietal cortex, thalamus, and caudate nucleus, among others. In addition, as some students felt the increase in the difficulty of working memory task performance, the orbitofrontal cortex and the hippocampus were activated, which seems to be the result of an effort for looking for an answer. More types of ADHD students needs to be secured as research subjects, and more stimulations for fMRI experiments should be considered as it would be useful in the overall evaluation of brain function.

• Journal of Animal Environmental Science
• /
• v.8 no.1
• /
• pp.25-34
• /
• 2002

In view of increasing environmental pollution, the organic farming in animal production is becoming increasingly urgent. The problems of veterinary medicine have not diminished through the most dangerous epidemic diseases. Organic farming attempts to function in harmony with the environment. The first criterion of the organic farm is that the animal must be self-sustaining. Their food must be produced to a large extent on the farm. The position of ruminants in biological systems is determined by the fact that this group of farm animals is provided with a digestive system which optimizes the utilization of the products of gut microfloral fermentation. The cattle do not require large amounts of concentrate feeling nor gross ugly farm building for intensive rearing. The economic profitability of a cow depends. on the first instance, on the level of milk production and the number of lactations. The length of life is an important factor since the tilde to maturing is relatively high in a cow. The result is that dairy cows in organic farming have greater length of live, and produce more milk in their life time than the shorter lived high input cow. This paper. therefore, discussed the problems of modern cattle farming and development trends of organic farming in Germany and Korea.

• Journal of the Korea Convergence Society
• /
• v.7 no.2
• /
• pp.53-59
• /
• 2016

Epilepsy is a neurological disease characterized by recurrent seizures. Though the exact causes for epilepsy are unknown, genetic mutations, especially altered gene functions, have been implicated as key causative components of epilepsy. We recently identified a causing gene for the Miles-Carpenter syndrome (MCS). MCS patients have intellectual disability and epilepsy. MCS knockout (KO) zebrafish also show a seizure-like phenotype with hyperactivity of pectoral fin and jaw movement, resulting from loss of GABAergic interneurons. To evaluate MCS KO zebrafish as an epilepsy model, we tested the effects of retigabine, an anticonvulsant drug, on the movement of MCS KO zebrafish.

• Journal of Fisheries and Marine Sciences Education
• /
• v.6 no.2
• /
• pp.183-189
• /
• 1994

1970년 이후 우리나라는 산업화로 인하여 사회구조와 가정구조가 크게 변화 되었다. 도시집중화로 인한 각종 공해 발생, 교통난, 인구이동의 문제를 비롯하여 그리고 핵가족화로 인한 가부장적 권위상실 및 가정교육부재, 청소년 비행등 수 많은 문제가 야기되었다. 특히 핵가족화로 발생된 심각한 사회문제는 전통윤리의 붕괴와 가정교육의 부재현상을 발생 시켰다. 이와같은 문제발생에 관한 선행연구를 종합해보면 첫째, 핵가족화로 인해 발생한 가족규모의 축소현상으로 자녀들의 다면적 인격형성에 결손을 초래하여 성장후 독립심과 의지가 약하고 고집이 세며 이기적이고 자기중심적인 성향이 되어 사회생활에 부적응 현상을 초래하게 되었다고 한다. 그 이유는 다면적 인간관계의 결여로 상호 협조하고 사랑을 교환한 경험 부족과 외동자녀에 대한 부모의 관심이 자녀의 욕구에만 집중되어 자녀종속적인 태도가 크게 적용하였기 때문이다. 둘째는 산업화 사회에서의 부부동시 사회참여가 자녀양육에 어머니와의 애착형성이 결여되어 모성실조를 겪게 된 문제를 들 수 있다. 어머니와 자녀간의 애착형성이 결여 됨으로 발생되는 문제는 지적 정체현상과 정서발달의 장애가 주 원인이 되어 감정 통제력이 약해서 공격적 행동이나 반 사회적 행동으로 확대되어 청소년문제 발생의 원이 되고 있음을 시사하고있다. 세째로 산업화사회와 경쟁력 조장을 들 수 있다. 산업사회를 개방사회, 경재력사회 혹은 능력사회라하여 고학력위주의 선발형태가 입시경쟁을 부추기고 있으며 그에 따라 많은 청소년들과 학부모들이 상위 지향적인 심리가 작용하여 자녀들의 입시경쟁에만 집중하게 되었다. 이러한 원인으로 인하여 인간교육 즉 가정교육을 외면하여 반도덕적, 반사회적 문제를 야기하게 하였다. 특히 전통적 가정윤리가 붕괴되어 부모에 대한 효관의 약화, 부부간의 애정약화 및 물질지향적인 사고가 이혼률을 증가시켜 가정붕괴를 가져왔다. 이상에서 논의된 자녀교육의 부재가 자녀들의 지적 정서적 문제로 확대되어 산업화사회의 모순점을 노출시키고 있음을 알 수 있다. 이와같은 문제를 해결하기 위한 대안으로 연구자가 제시하는 방안은 훌륭한 가정교육을 위해서 우선되어야 하는것은 부모자신의 인격적 개인완성을 제안하였다. 인격의 완성은 양심과 행동이 일체하는 사람을 지칭한다. 다음은 서로 위하여 사는 삶을 영위하는 인격체가 되어 양심의 법에 따르는 삶, 타인을 위하여 사는 삶을 자녀들에게 보여줌으로서 반두라의 모델링 교육을 제안하였다. 마지막으로 오늘날과 같은 암기위주의 경쟁교육이 아니라 타고난 잠재성 개발에 주력하는 교육으로, 적성과 소질을 개발하는 창조적 산 교육장을 마련하여 주고 또한 그것을 뒷바침하는 가정윤리교육의 회복이 무엇보다도 이 시대가 절실히 요구하는 바람직한 교육이라 하겠다.

• Journal of Preventive Medicine and Public Health
• /
• v.26 no.4 s.44
• /
• pp.628-649
• /
• 1993

This study was conducted to investigate the factors related to the poor school performance of the elementary school children. Two schools in Taegu, one in the affluent area and the other in the poor area, were selected and a total of 175 children whose school performance was within low 10 percentile (poor performers) and 97 children whose school performance were within high 5 percentile (good performers) in each class of 2nd, 4th and 6th grades were tested for the physical health, behavioral problem and family background. Each child had gone through a battery of tests including visual and hearing acuity, anthropometry (body weight, height, head circumference), intelligence (Kodae Stanford-Binet test), test anxiety (TAI-K), neurologic examination by a developmental pediatrician and heavy metal content (Pb, Cd, Zn) in hair by atomic absorption spectrophotometry. A questionnaire was administered to the mothers for prenatal and prenatal courses of the child, family environment, child's developmental history, and child's behavioral and learning problems. Another questionnaire was administered to the teachers of the children for the child's family background, arithmatic & language abilities and behavioral problem. The poor school performance had a significant correlation with male gender, high birth order, broken home, low educational and occupational levels of parents, visual problem, high test anxiety score, attention deficit hyperactivity disorder (ADHD), poor physical growth (weight, height, head circumference) and low I.Q. score. The factors that had a significant correlation with the poor school performance in multiple logistic regression analysis were child's birth order (odds ratio=2.06), male gender(odds ratio=5.91), broken home(odds ratio=9.29), test anxiety score(odds ratio=1.07), ADHD (odds ratio=9.67), I.Q. score (odds ratio=0.85) and height less than Korean standard mean-1S.D.(odds ratio=11.12). The heavy metal contents in hair did not show any significant correlation with poor school performance. However the lead and cadmium contents were high in males than in females. The lead content was negatively correlated with child's grade(P<0.05) and zinc was positively correlated with grade (P<0.05). among the factors that showed a significant correlation with the poor school performance, high birth order, short stature and ADHD may be modified by a good family planning, good feeding practice for infant and child, and early detection and treatment of ADHD. Also, teacher and parents should restrain themselves from inducing excessive test anxiety by forcing the child to study and over-expecting beyond the child's intellectual capability.

• Journal of The Korean Society of Inherited Metabolic disease
• /
• v.18 no.3
• /
• pp.99-106
• /
• 2018

Mucolipidosis type III (pseudo-Hurler polydystrophy) is a mucolipids degrading disorder caused by a mutation in the GNPTAB gene and is inherited by autosomal recessive. It is diagnosed by examining highly concentrated mucolipids in blood and the diagnosis can be confirmed by genetic testing. Mucolipidosis type III is a rare and progressive metabolic disorder. Its initial signs and symptoms usually occur around 3 years of age. Clinical manifestations of the disease include slow growth, joint stiffness, arthralgia, skeletal abnormalities, heart valve abnormalities, recurrent respiratory infection, distinctive facial features, and mild intellectual disability. Here, we are presenting two siblings of mucolipidosis type III, a 4-year-old female and a 2 years and 7 months old male with features of delayed growth and coarse face. The diagnosis was confirmed by [c.2715+1G>A(p.Glu906Leufs*4), c.2544del(p.Glu849Lysfs*22)] mutation in targeted gene panel sequencing. In this case, c.2544del is a heterozygote newly identified mutation in mucolipidosis type III and was not found in the control group including the genome aggregation database. And it is interpreted as a pathogenic variant considering the association with phenotype. Here, we report a Korean mucolipidosis type III patients with novel mutations in GNPTAB gene who have been treated since early childhood. Owing to recent development of molecular genetic techniques, it was possible to make early diagnosis and treatment with pamidronate was initiated appropriately in case 1. In addition to these supportive therapies, efforts must be made to develop fundamental treatment for patients with early diagnosis of mucolipidosis.

• The Journal of Korean Academy of Sensory Integration
• /
• v.17 no.1
• /
• pp.54-64
• /
• 2019

Objective : The purpose of this study is to study the effects of multisensory environment interventions, to provide information about clinical applications, and to aid South Korean research on the multisensory environment. Methods : PubMed, Cochrane, and Google Scholar were used to search for papers published from 2008 to 2018. The main search terms were "multisensory environment" and "snoezelen", a total of 10 foreign research articles were selected. And they were summarized according to Patient, Intervention, Comparison, Outcome (PICO). Results : Among the 10 papers, 6 included participants with dementia. The other studies examined patients with intellectual disabilities, patients with schizophrenia, and pregnant women. The study periods ranged from 3 weeks to 10 months. Most of the interventions included 2 or 3 sessions per week. The duration of each intervention session was 30 to 60 minutes. The dependent variables were psychological factors (such as anxiety and depression), social factors (such as quality of life), and cognitive and physical domains. The multisensory environment used for the interventions in the studies consisted of visual, auditory, and tactile senses, as well as additional olfactory and taste sensations, and vestibular sensations. Conclusion : In the future, the research should be applied to various target groups, especially children, who are interested in multisensory environmental intervention in South Korea.