• Title/Summary/Keyword: 지방 괴사

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Concurrent Liposarcoma and Fat Necrosis in an Encapsulated Mass: Report of a Case (지방괴사와 동반된 지방육종 - 증례 보고 -)

  • Kang, Hyun-Guy;Min, Hye-Sook;Cho, Hwan-Seong
    • The Journal of the Korean bone and joint tumor society
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    • v.14 no.2
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    • pp.187-191
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    • 2008
  • Encapsulated fat necrosis is a degenerative process involving various mature adipose tissues. Liposarcoma may also occur in any body fat area but it is quite different from lipoma and fat necrosis. Moreover, sarcoma does not derive from lipoma. We present a case of liposarcoma accompanying extensive fat necrosis in an well-encapsulated mass.

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Epipericardial Fat Necrosis in a Pediatric Patient Diagnosed Using Contrast-Enhanced MRI Findings: A Case Report and Literature Review (소아 심장막 주위 지방 괴사 환자에서의 조영증강 자기공명영상 소견: 증례 보고 및 문헌고찰)

  • Seong Ju Kim;Byoung Hee Han;Youngjong Cho;Dae Shick Ryu;Ga Young Yoon;Wooyul Paik;Young Rae Kim
    • Journal of the Korean Society of Radiology
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    • v.83 no.5
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    • pp.1160-1167
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    • 2022
  • Epipericardial fat necrosis (EPFN) is a relatively rare cause of acute chest pain, with only five pediatric cases having been reported in the English-language medical literature to date. EPFN can be diagnosed based on the clinical symptoms of acute pleuritic chest pain and classic CT features of typically ovoid fatty lesions surrounded by a rim or capsule in the mediastinal or pericardial areas. Previous studies have reported that contrast-enhanced MRI can detect typical fat signal changes in adults with EPFN. We report a pediatric EPFN case diagnosed using gadolinium-enhanced MRI. Thus, contrast-enhanced MRI may be used to confirm EPFN in the differential diagnoses of the causes of acute chest pain.

Effects of Protaetia Orientalis (Gory et Perchlon) Larva on the Lipid Metabolism in Ethanol Administered Rats (굼벵이의 섭취가 에탄올 투여 흰쥐의 지질대사에 미치는 영향)

  • 강일준;김하경;정차권;김수진;오덕환
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.29 no.3
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    • pp.479-484
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    • 2000
  • 흰쥐에 에탄올을 투여해 간 손상을 유도한 후 굼벵이를 투여해 굼벵이가 혈청과 간의 지진대사에 어떠한 영향을 미치는가를 조사하였다. 혈청지질 중 에탄올에 의해 증가된 triglyceride, 총 cholesterol은 굼벵이를 섭취시킴으로써 이의 수치를 감소시켰으며 HDL-cholesterol은 굼벵이의 섭취로 triglyceride 함량은 감소되었다. GOT와 GPT의 활성은 에탄올 투여시 정상식이에 비해 유의적인 증가를 보인 반면, 굼벵이의 섭취로 유의적인 감소를 나타내었다. (p<0.05). 에탄올 추여군의 간조직 세포는 세포질에 지방소적의 축적으로 세포질의 부분적인 괴사현상이 나타났으며 조면소포체와 mitochondria의 형태적 변형이 관찰되었다. 에탄올과 굼벵이의 병용투여군은 지방소적의 크기 및 양적 감소와 세포질의 괴사현상이 약간 회복 되었으나 조면소포체와 mitochondria의 수적인 증가는 미미하였다.

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Morphologic Change of Rat Liver Induced by Repeated Administration of Carbon Tetrachloride and Dimethylnitrosamine (사염화탄소와 Dimethylnitrosamine의 반복투여가 백서간의 형태학적 변화에 미치는 영향)

  • Lee, Tae-Sook
    • Journal of Yeungnam Medical Science
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    • v.4 no.1
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    • pp.89-96
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    • 1987
  • Carbon tetrachloride and Dimethylnitrosamine, both potent hepatotoxic agents, affect the hepatic lobules with fatty changes and central necrosis, and hemorrhagic necrosis. To study the effects on morphologic changes of the hepatic lobules in cases of single and repeated treatment of both hepatotoxins, sublethal doses of carbon tetrachloride, 0.4ml/kg, and dimethylnitrosamine, 40mg/kg of rats were given intraperitoneally single, twice and triple. With interval of 3 days, and the results were as follows : 1. The fatty changes and central necrosis of the hepatic lobules were milder and more quickly disappeared in the rats with twice or triple treatment than single administration of carbon tetrachloride, and regenerative changes of hepatic and sinusoidal cells achieved fater in the rats with repeated administration of carbon tetrachloride than those with single treatment. 2. The hemorrhagic necrosis of the hepatic lobules was not significantly influenced by the times of DMN treatment, but the hyperplastic changes showed more active to animals, with multiple administration of DMN.

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Preventive Effect of Lamprey Oil and Corn Oil on the Experimental Atherosclerosis in Rats (랫트의 실험적 동맥경화증에 대한 칠성장어유 및 옥수수유의 예방적 효과)

  • 이범준;이영순;미끼도꾸타로
    • Journal of Food Hygiene and Safety
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    • v.4 no.2
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    • pp.133-153
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    • 1989
  • The present study was carried out to investigate the preventive effects of lamprey oil and corn oil on atherosclerotic rats induced by oral administration of cholesterol and vitamin $D_2$. The obtaind results were summarized as fellows; 1. The group, fed only the mixture of cholesterol and vitamin $D_2$ showed the significant increase of total lipid, total cholesterol phospholipid, LDL&HDL-cholesterol in the serum, triglyceride and cholesterol in the heart and the aorta, but the significant decrease of triglyceride in the liver, as comparing with normal control group (p<0.05). The aorta showed the severe damage of disorganization, calcification, necrosis and lipid deposition in the aortic wall. 2. The group, adminstered the mixture of cholesterol and vitamin $D_2$ and fed 15% lamprey oil diet, showed the significant decrease of total lipid, triglyceride, total cholesterol, phospholipid and LDL&VLDL-cholesterol in the serum, triglyceride and cholesterol in the heart and the aorta, but the significant increase of cholesterol in the liver, as comparing with atherogenic control group (p<0.05). The aorta showed slight calcification and no lipid deposition in the aortic wall as comparing with atherogenic control group. 3. The group, administerd the mixture of cholesterol and vitamin $D_2$ and fed 15% corn oil diet, showed the decrease of total lipid, triglyceride and VLDL-cholesterol in the serum, and triglyceride in the heart and the aorta, as comparing with atherogenic control group (p<0.05). The aorta showed calcification and no lipid deposition in the aortic wall. In reviewing above results it was concluded that lamprey oil and corn oil in polyunsaturated fatty acids had the preventive effect on atherosclerotic rats induced by cholesterol and vitamin $D_2$. And the effect of lamprey oil in n-3 polyunsaturated fatty acids was higher than that of corn oil rich in n-6 polyunsturated fatty acids.

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