• Clinical and Experimental Pediatrics
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• v.52 no.6
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• pp.655-660
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• 2009

Purpose : To compare birth weight between infants with a single umbilical artery (SUA) and normal infants, investigate the associated anomalies of infants with SUA and isolated SUA (no abnormality of external appearance on birth, except SUA), and determine the prognosis of infants with isolated SUA. Methods : Live-born infants with SUA (n=59) detected by physical examination from among 15,193 live births in seven university hospitals in Korea between January 1, 2004, to August 1, 2007, were reviewed retrospectively, with 236 normal infants serving as the control group. Results : A statistical difference was observed between the groups in birth weight and in vitro fertilization. The incidence of infants with SUA was 0.37%. Congenital malformations were observed in 21 infants with cardiovascular (n=15, 25.4%), gastrointestinal (n=2, 3.4%), genitourinary (n=9, 15.3%), neuromusculoskeletal (n=6, 10.2%), central nervous system (n=1, 1.7%), chromosomal (n=1, 1.7%), and other (n=3, 5.1%) abnormalities. There were 49 (83.1%) infants with isolated SUA in this study population; among them, the associated congenital malformations were cardiovascular (n=6, 12.2%) and genitourinary (n=6, 12.2%) abnormalities. Two infants with cyanotic heart disease were operated and four infants with acyanotic heart disease showed improvements without any treatment. Six infants with genitourinary abnormalities on renal ultrasound had mild hydronephrosis without further consequences. Conclusion : The incidence of structural abnormalities in the cardiovascular and genitourinary systems is high and the genitourinary anomalies associated with isolated SUA have relatively good prognosis.

• Clinical and Experimental Pediatrics
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• v.51 no.8
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• pp.848-855
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• 2008

Purpose : The objective of this study was to ascertain the incidence of congenital heart disease in the western part of Gyeongnam Province in Korea. Methods : We enrolled 849 children (M:F=390:459) who were diagnosed with congenital heart disease (CHD) and received echocardiography during January 1997 to December 2005 in Gyeongsang National University Hospital. The subjects were limited to patients born from 1997 to 2004. The CHDs were classified into acyanotic types and cyanotic type. Further, acyanotic type CHDs were divided into shunt type and valvular types. Results : Numbers of initially diagnosed patients from 1997 to 2004 were as follows: 113, 128, 116, 104, 129, 97, 84, and 78. The median age of initially diagnosed CHD patients was 1 month in the acyanotic type and 0.5 months in cyanotic type. Also, an annual frequency among CHD types and gender ratio were no significant difference in every year. Incidences of CHD from 2000 to 2004 in the western part of Gyeongnam Province were 8.9, 12.7, 10.9, 10.0, and 9.7 per 1,000 live births, respectively. Conclusion : From 1997 to 2001, 100-130, and from 2002 to 2004, less than 100 patients were diagnosed with CHD. This showed a decrease in the numbers of CHD patients in the last three years. However, the Incidence of CHD was 0.89-1.24% during the last five years. Therefore, the decrease in the annual frequency of CHD was due to the recent decline in birth rate in Korea.

• 한국해양학회지
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• v.18 no.1
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• pp.55-63
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• 1983

The study on the periodic and correlation analysis between water temperature and air temperature has beenconducted by oceanographic data obtained from 1923 to 1979 (For 16-51 years) in 6 ststions in the Korean Waters. The periodic and correlation analyses has been examined by method of he Schuster's and the quadratic formula of least squares method, respectively. The results pbtained from the study are as follows; 1. Periodic analysis 1) The yearly difference between max. and mini. fo surface water temperature was 12.77-17.99$^{\circ}C$ (computed value : 11.67-16.64$^{\circ}C$) in offshore waters, and was 15.72-26.33$^{\circ}C$ (computed value : 15.13-25.29$^{\circ}C$) in inshore waters, and that of air temperature was 21.71-28.60$^{\circ}C$ (computed value : 10.50-27.22$^{\circ}C$). 2) The yearly mean of water temperature by station was 11.25-18.78$^{\circ}C$, and that of air temperature was 11.39-16.16$^{\circ}C$. 3) The annual compnent amplitrde of water temperature was 5.72-12.54$^{\circ}C$, and that of air temperature was 10.04-13.49$^{\circ}C$. 4) The semi-annual component amplitude of water temperature was 0.83-1.30$^{\circ}C$, and that of air temperature was 0.72-1.26$^{\circ}C$. 5) The annual component phase of water temperature was 215-228$^{\circ}C$ (max. temperature shall be in the first and in the middle ten days of August) in inshore waters and 138-244$^{\circ}C$ (max. temperature shall be in the first and in the middle ten days of August) in offshore waters, and that of air temperarture was 212-221$^{\circ}C$ (max. temperature shall be in the first and in the middle ten days of July and in the first tin days of August). 6) The semi-annual component phase of water temperature was 87-110$^{\circ}C$ in offshore waters, and 167-212$^{\circ}C$ in inshore waters, and that of air temperature was 156-189$^{\circ}C$. 2. Correlation analyses of water temperature and air temperature before one month. 1) When the water temperature is in rising time, the quadratic constant of correlation formual was the gradual inreasing type ( constant; 0.010-0.026) in offshore waters, and the gradual decreasing or proportional type (constant; -0.020-0.001) in inshore waters. 2) when the water temperature is in descending time, the quadratic constant of correlation formula was the gradual increasing type (constant: 0.012-0.021) 3) the determination coefficient was 0.964-0.992 at rising time and 0.982-0.999 at descending time of water temperature.

• Tuberculosis and Respiratory Diseases
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• v.62 no.2
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• pp.98-104
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• 2007

Background: Although there is an increasing incidence of Mycobacterium abscessus pulmonary disease in Korea, the optimal therapeutic regimen has not yet been established and there are no reports of the long-term treatment outcomes. This study examined the long-term treatment outcomes of M. abscessus pulmonary disease. Methods: Twenty-nine patients diagnosed with M. abscessus pulmonary according to the American Thoracic Society criteria and treated from January 1996 to December 2003 were enrolled in ghis study. The clinical characteristics, radiological findings, treatment outcome, and follow up data were analyzed retrospectively. Results: The mean age of the 29 patients was 56.1 (${\pm}13.6$) years and there was a female (22/29) dominance. The chest radiography revealed the nodular bronchiectatic type to be dominant (69%, 20/29). Twenty-seven (93.1%) were prescribed clarithromycin-containing regimens, and injectable drugs, mainly aminoglycosides, were included in the regimen of nineteen patients. The most predominant regimen (48.3%) consisted of clarithromycin and amikacin. The treatment success, failure, and default were achieved in 19(65.5%), 9(31.0%), and 1(3.4%), respectively. The median duration to culture conversion was 42 days (range 15-362) and the median duration of treatment in the success group was 543 days (range 176-1,160). An adjunctive surgical resection was performed in five patients, which resulted in treatment success in two patients. After the completion of treatment, nineteen patients were followed up for a median duration of 931 days (range 230-2,294). Only one (5.3%) patient relapsed 45 days after completing treatment. Conclusion: Treatment with clarithromycin-containing regimens resulted in a successful treatment in approximately two thirds of patients with M. abscessus pulmonary disease. The long-term relapse rate was also quite low.