• Title/Summary/Keyword: 중추

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Stress and Immune Function (스트레스와 면역기능)

  • Koh, Kyung-Bong
    • Korean Journal of Psychosomatic Medicine
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    • v.4 no.1
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    • pp.146-154
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    • 1996
  • The impact of stress on immune function is known to be associated with the interactions among the central nervous system(CNS), neuroendocrine system, and immune system. The main pathways between stress and immune system are wiring of lymphoid organs and neuroendocrine system. Immune system also produces neuropeptides, which modulate immune system. Mediators of psychosocial influences on immune function are found to be peptides released by the pituitry, hormones, md autonomic nervous system. Hypothalamus integrates endocrine, neural and immune systems. Particularly, paraventricular nucleus appears to play a central role in this integration. On the other hand, endocrine system receives feedback from the immune system. The major regulatory pathways which pituitary modulates include the hypothalamic-pituitary-adrenal-thymic(HPAT) axis, hypothalamic-pituitary-gonadal-thymic(HPGT) axis, pineal-hypothalamic-pituitary(PHP) axis. Bidirectional pathways such as feedforward and feedback pathways are suggested in the interaction between stress and immune system. It suggests that psychosocial inputs affect immune function, but also that immunological inputs affect psychosocial function. Thus, prospective studies for elucidating the relationship between stress and immune function should incorporate measures of immune function as well as measures of endocrine, autonomic, and brain activities at the same time.

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Development of the Central Nervous System in the Wolf Spider Arctosa kwangreungensis (Araneae: Lycosidae) (광릉늑대거미(Arctosa kwangreungensis) 중추신경계 발생에 관한 연구)

  • Yang, Sung-Chan;Moon, Myung-Jin
    • Applied Microscopy
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    • v.42 no.2
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    • pp.77-86
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    • 2012
  • The morphological and histologic differentiation of the central nervous system (CNS) in the wolf spider Arctosa kwangreungensis with respect to postembryonic development are studied using light and scanning electron microscopes. The organization of CNS which consisted of supraesophageal ganglion (SpG) and subesophageal ganglion (SbG) are established prior to the postembryo stage. The brain of first instar spiderling after a molt of the postembryo is also made up of supraesophageal ganglion and subesophageal ganglion. Although development of the optic nerve and optic lobe in SpG are not completed during the postembryoic stage, completion of whole neural system resemble to that of adult are established during the second instar stage. In particular, optic gangalion is developed from the undifferentiated cell clusters of the SpG, moreover four pairs of appendage ganglia and another pairs of abdominal ganglia are produced from the SbG. Nerve cells of the most developing stages are composed of typical monopolar neur1ons, and total three types of neurons can be identified through the histological and morphological basis of present study. These cell clusters are differentiated into neurons and grow dendritic fibers according to further development of the CNS.

Difference of Sensory Changes by Central and Peripheral Stimulation for Improving Life Care in Chronic Low Back Patients (만성 허리통증환자의 라이프 케어 증진을 위한 중추성과 말초성 자극에 따른 감각변화의 차이)

  • Kim, Kyung-Yoon;Park, Chi-Bok
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.8
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    • pp.221-230
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    • 2020
  • This study aimed to investigate the difference of sensory changes by central and peripheral stimulation for improving life care in chronic low back pain patients. Twelve chronic low back pain patients were randomly assigned to central stimulation (CS, n=6) and peripheral stimulation (PS, n=6). Quantitative sensory test (QST), pressure pain threshold (PPT) and Korean oswestry back pain disability index (KODI) were used to quantitatively measure and analyze. As a result, QST, PPT and KODI showed significant differences by period (p<.01) but did not showed any difference between the two groups (p>.05). Therefore, both stimulations had significant effects on increased sensory threshold and function improvement of the muscles that became sensitive due to pain. It is thought to be significant in improving life care for patients with chronic low back pain.

A case of Behcet's Disease with CNS Manifestations (중추 신경계 증상이 동반된 Behcet,씨 병 1예)

  • Shin, Dong-Gu;Ko, Myung-Ku;Yoon, Kyung-Woo;Kim, Chong-Suhl
    • Journal of Yeungnam Medical Science
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    • v.3 no.1
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    • pp.307-311
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    • 1986
  • Beh,cet's disease was originally described as a triple symptom complex of oral aphthous ulceration, genital ulceration, and hypopyon iritis. It is now known to have a wide systemic manifestations. Among them, the central nervous system involvement should be diagnosed earlier because of it's lethal potential. Recently the authors experienced a case of Behcet's disease with CNS involvement. A 51-year-old female patient was admitted due to deterioration of mentality and generalized ache since 2 years prior to admission. The findings on physical examination were compatible with Behcet's disease, but without cerebrospinal pleocytosis. The manifestations were improved with medications of prednisolone, chlorambucil, colchicine, but relapsed 2 months later during subsequent tapering of prednisolone and chlorambucil. The patient is now on medication again. A case of Beh,cet's disease with CNS manifestations is reported with review of literature.

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A Case of Incontinentia Pigmenti with Developmental Brain Malformation (중추 신경계 발달이상을 동반한 색소실소증 1례)

  • Kang, Suk Ho;Kim, Soon;Jung, Seung Hee;Lee, Sang Geel
    • Clinical and Experimental Pediatrics
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    • v.45 no.4
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    • pp.535-539
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    • 2002
  • Incontinentia pigmenti is a rare neurocutaneous syndrome characterized by vesiculobullous skin disease in neonates and infants, a noninfectious disease that should be distinguished from infectious diseases with the neonatal seizure or encephalopathy. This disease is X-linked dominant with Xq28 region abnormalities and often associated with developmental defects of the ocular, skeletal, dental, and central nervous system. Central nervous system involvement in the neonatal period, or complicated by encephalopathy, may cause severe neurologic impairment, retardation or even death. We experienced a case of incontinentia pigmenti in a three-day-old female patient who had characteristic papulovesicular skin lesions and partial seizures with secondary generalization. Histopathological examination favored the diagnosis of incontinentia pigmenti and a brain MRI showed undifferentiated white matters with periventricular nodular lesions.