• Title/Summary/Keyword: 중심분사

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상한(傷寒) 의학사(醫學史)에 관(關)한 연구(硏究) (III) - 상한학파(傷寒學派)의 형성과 발전시기(명${\sim}$청)(明${\sim}$淸)를 중심으로 -

  • Kim Gi-Uk;Park Hyeon-Guk;Jeong Seong-Chae
    • Journal of Korean Medical classics
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    • v.13 no.1
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    • pp.146-183
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    • 2000
  • 통과이상적연구(通過以上的硏究), 장상한학술적성숙기(將傷寒學術的成熟期), 칙지명대여청대관여상한의학사적내용정리(則至明代與淸代關與傷寒醫學史的內容整理) 여하(如下). 1. 명청시대적시대배경사상한학적내용갱풍부(明淸時代的時代背景使傷寒學的內容更豊富), 촉진상한학술적발전(促進傷寒學術的發展) 병차출현료흔다관여상한적저작(幷且出現了?多關與傷寒的著作), 단실제상야출현료상한론내용적중복여지론술일반부분(但實際上也出現了傷寒論內容的重複與只論述一般部分), 혹저자립안조잡적처방지폐단(或著者立案粗雜的處方之弊端). 차기우출현각종상한학파적리유(此期又出現各種傷寒學派的理由), 시인위당시류행적사조(是因爲當時流行的思潮), 칙정주리학적영향여명대문단부고(則程朱理學的影響與明代文壇復古), 의고적추향(擬古的趨向), 환유금원시대적백가쟁오등(還有金元時代的百家爭嗚等), 성료형성상한학파적기초(成了形成傷寒學派的基礎). 2. 위료불실거상한론적본래의식(爲了不失去傷寒論的本來意識), 주장정리화고정원문회부왕숙화이전모양적착간중정파시왕안도기료개단(主張整理和考訂原文恢復王叔和以前模樣的錯簡重訂派是王安道起了開端), 방유집확대료기의식(方有執擴大了其意識). 유창여침명종시대표저학파학자(喩昌與沈明宗是代表這學派學者), 장로(張?) 정응모(程應?) 주양준(周揚俊) 오겸등수료저학설(吳謙等隨了這學說). 3. 주장(主張)'존왕(尊王)(숙화(叔和))찬성(贊成)(무기(无己))'적유호구론파(的維護舊論派), 주장료불능수변개상한론삼음삼양편적배렬여순서(主張了不能隨變改傷寒論三陰三陽篇的排列與順序), 문자(文字), 구문(句文), 문장(文章), 고세식(高世?), 진념조등인(陳念祖等人). 4. 주장상한론적정수재어변증론치(主張傷寒論的精髓在於辨證論治), 선우운용칙능득상한핵심리론적학파시변증론치학파(善于運用則能得傷寒核心理論的學派是辨證論治學派). 저학파분사개계통(這學派分四?系統), 이처방수집증상적의가유허굉(以處方收集證狀的醫家有許宏), 가금(柯琴), 서대춘(徐大椿); 이치법수집증상적의가유오인구(以治法收集證狀的醫家有吳人駒), 우이(尤怡); 이분유륙경찰증상적의가유진념조(以分有六經察證狀的醫家有陳念祖), 포성(包誠); 이증상분류증후적의가유류순(以證狀分類證候的醫家有劉純), 왕긍당(王肯堂), 진지정(秦之楨), 침금오등인(沈金鰲等人). 5. 회통파유량종류형(?通派有兩種類型), 일시수통상한여온병적학파(一是誰通傷寒與溫病的學派), 간칭회통파(簡稱?通派), 대표의가유도화(代表醫家有陶華), 오정(吳貞), 유근초등인(兪根初等人), 령일개유회통중의여서의적립장상해석상한적의가당종해(?一?有?通中醫與西醫的立場上解釋傷寒的醫家唐宗海). 6. 경전학파시이상한론위보귀적경전래인식(經典學派是以傷寒論爲保貴的經典來認識), 병차지유숭상차경여사상적학파(幷且持有崇尙此經與思想的學派), 차리분량개편우원문적고증래연구적경전고증파(此里分兩?偏于原文的考證來硏究的經典考證派), 화인위지유상한론(和認爲只有傷寒論), 재능총괄치료외감병(才能總括治療外感病), 부정온병학설병배척적경전림상파(否定溫病學說幷排斥的經典臨床派).

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Application of DNA microarry : Comparative functional genomic approach

  • Chu In-Sun
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2006.02a
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    • pp.109-114
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    • 2006
  • 최근 Human 지놈 프로젝트를 포함한 다양한 종의 지놈 프로젝트가 수행되고 수많은 지놈정보가 생산되고 있으며 이를 해석하고 서로 연관성를 찾기 위한 다양한 연구가 진행되고 있다. 즉 최신 생명공학과 관련된 연구방향이 DNA의 구조적 해석에서 기능 해석과 유전자들의 상호연관성을 규명하는 방향으로 변화하고 있으며 이를 위한 강력한 도구로서 DNA microarray (DNA chip)는 방대한 양의 지놈 정보를 이용하여 단시간에 대량으로 고속처리하여 효율적으로 유전자 기능을 분석할 수 있는 주목받고 있는 방법이다. DNA microarray 실험과 분석에 있어 데이터분석, 재현성, 종간의 비교, 확인실험 및 비용 등의 문제가 있지만 유전자발현양상 데이터로부터 정확한 환자의 예후를 예측할 수 있는 비교적 적은 유전자 그룹의 진단마커를 찾거나, 하나의 유전자가 아니라 mouse 전체 지놈의 유전자발현 패턴을 인간의 암을 위시한 각종 질병 연구를 위한 발현 신호나 변화 등을 발견하여 신약개발 등에 활용하고자 하는 시도가 활발히 진행되고 있다. 서로 다른 종간에 비슷한 phenotype의 유전자발현도 진화적으로 보존되었다는 전제 하에서 지놈 sequence의 비교연구가 가능하고 DNA microarray 발현 데이터에 근거하여 독립적으로 각 종간의 유전자발현패턴을 비교함으로써 난치병 등을 새롭게 분류할 수 있다. 즉, 암세포 등에서 유전자발현 양상은 유전학적, 환경적 alteration들이 잘 반영되어 있다고 간주하고, 이러한 양상을 바탕으로 인간의 암을 위시한 다양한 질병 연구를 위한 최적의 mouse 모델을 찾을 수 있고, 이는 결국 새로운 치료 방법 개발이나 맞춤의학 실현에 중요한 역할을 할 것으로 기대된다. 특히 pathway 타겟으로 하는 치료를 위해서는 Human-mouse 비교를 통한 발현 신호를 찾는 것이 진단에서는 매우 유용한 방법이다. 이를 위한 고성능의 분석방법이나 시스템의 개발이 중요하게 된다.. 관류의 정도와 조영증강정도를 중심으로 관류 MR 영상소견과 조직학적 소견을 관련지어 분석하였다. 결과: 조영증강 T1강조MR영상에서 환상조영증강을 보이는 다형성 교보세포종 2예에서는 변연부 외륜이 고관류를, 중심부의 괴사부위는 저관류로 나타났다. 저등급 교종은 경계가 불분명한 저관류부위로 보였다. 뇌농양 2예는 변연부 외륜이 경도의 고관류를, 중심부는 저관류로 나타났다. 뇌수막종은 미만성의 균일한 중등도 혹은 고도의 고관류로 보였으며, 임파종과 배아종은 경계가 명확한 저관류부위로 나타났다. 신경세포종은 종괴\ulcorner 일부에 중등도 혹은 고도의 고관류부위가 관찰되었고, 전이암은 다수병변중 일부에서 중등도의 고관류를 보였다. 방사선괴사는 저관류부위내에 국소적 고관류부위를 보였다. 결론: 관류 MR영상은 뇌종양의 관류상태를 비교적 잘 반영하며, 조직학적 특성을 예측하는데에 도움을 주 수 있을 것으로 기대된다. 뇌종야에서의 관류MR영상의 분명한 역할을 규명하기 위해서는 앞으로 더 많은 임상적 연구가 필요할 것으로 생각된다.조증 환자의 자극성 전타액내 lactobacilli양은 peroxidase system을 함유한 세치제를 사용한 군에서 대조군에 비해 상대적으로 낮게 나타났으나(p = 0.067) 통계학적 유의성은 없었다.같은 예에서 찾아 볼 수 있다. 첫째, 발음상으로 동사의 변화형에서 "porte[$p{\jmath}rte$](들다: 현재형), porte[$p{\jmath}rte$](과거분사형), porta[$p{\jmath}rte$](단순과거형)"등이 대립되며, 이휘 "Porto[$p{\jmath}rte$](포르토)"와도 대립된다. 둘째, 어휘적 대립 "le haut[$l{\partial}o$](위)/l'eau[lo](물)"와 형태론적 대립 "le[$l{\partial}$](정관사, 남성단수)/l

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A Study on the Atomizing Mechanism for the Swirl Nozzle (와권(渦卷) 노즐의 무화기구(霧化機構)에 관(關)한 연구(硏究))

  • Lee, Sang Woo;Sakai, Jun;Ishihara, Akira
    • Korean Journal of Agricultural Science
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    • v.14 no.1
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    • pp.81-97
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    • 1987
  • Two nozzles with different size (Figure 2) were particularly designed to supply air through the swirl core into the central part of the liquid stream in the same parallel direction to produce a well-mixed air and water in the whirl chamber as spray liquid in bubble formation. Atomization was attempted to improve by using both the preliminary break-up process with less viscosity and less surface tension in the whirl chamber and the effects of increased frequency of the band of drops with the raised ambient air density in front of the nozzle orifice. The volumetric ratio between spray liquid and air on four levels was used to investigate the effects of air as a component of the mixture on atomization. The results of the experiment were summarized as follows; Droplet size became progressively finer as the operating pressure was increased in the range of $0.70kg/cm^2$ to $6.33kg/cm^2$, which was similar to the previous works. The new atomizing mechanism so-called 'air-center nozzle' gave a narrower range in droplet size distribution with smaller volumetric median diameter (VMD) than that of the existing spray system at a given pressure, which showed the possibility of improvement of atomization in a certain limit. The volumetric median diameter produced by the new atomizing mechanism was decreased from the central region toward the exterior edges across the spray pattern.

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A Study on the Buddhist Stone Arts of Mt. Bukhan (북한산 불교 석조미술 연구)

  • Lee, Seohyun
    • Korean Journal of Heritage: History & Science
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    • v.52 no.1
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    • pp.90-119
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    • 2019
  • The purpose of this study is to investigate the significance of Buddhist stone art in the cultural zone of Mt. Bukhan. Mt. Bukhan witnessed the prevalence of Buddhist culture in and around it since the introduction of Korean Buddhism and served as the center of Buddhist culture in the nation, where new Buddhist temples continued to be built from the Three Kingdoms Period to the Joseon Period. Of the characteristics of its Buddhist culture, it is very noteworthy that the construction of military temples in and around it in the latter half of Joseon supported the function of Buddhist temples as basic places of worship. These military temples were closely related to the mountain's geopolitical location, traffic routes, and position in the national defense system-- its mountain fortress was an important defense facility. The stone art works of Mt. Bukhan can be categorized into various types, including stone stupas, stone pagodas, rock-carved Buddhas, stone Buddhas, towers and monuments (stone monuments), stone lanterns, flagpole supports, and rock-carved sarira pagodas. There are diverse types of stone art left on the mountain. As for its period characteristics, it is clear that the Buddhist art of Silla spread even to the Gyeonggi region, and that most of the works of stone art were created during the first half of Goryeo and the latter half of Joseon. Starting in Goryeo, the Buddhist temples of the mountain maintained close relations with the royal court by operating as the royal buddhist shrine for the royal family. In the latter part of Joseon, the construction of the Bukhan mountain fortress became the most important opportunity to produce stone art. As for the distribution of the stone artwork, it was usually created in the west part of the mountain from Unified Silla to the first half of Goryeo and in the southern and eastern parts of the mountain from the latter half of Goryeo to the latter half of Joseon. It is estimated that central Buddhist temples of the mountain changed due to Silla's military goal of advancing toward the west coast along the Han River in its early days and the construction of the Bukhan mountain fortress in the latter half of Joseon to protect the capital city. Finally, the stone art of Mt. Bukhan holds very high significance in art history because various types of stone art continued to be created on and around the mountain, the stone artwork of the mountain reflected representative styles for each period, and e rare and ofthe works produced on the mountain exemplified rare and unique styles.

An Exploratory Study on the Success Factors of Silicon Valley Platform Business Ecosystem: Focusing on IPA Analysis and Qualitative Analysis (실리콘밸리 플랫폼 기업생태계의 성공요인에 관한 탐색적 연구: IPA 분석과 질적 분석을 중심으로)

  • Yeonsung, Jung;Seong Ho, Lee
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.18 no.1
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    • pp.203-223
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    • 2023
  • Recently, the platform industry is rapidly growing in the global market, and competition is intensifying at the same time. Therefore, in order for domestic platform companies to have global competitiveness in the platform market, it is necessary to study the platform business ecosystem and success factors. However, most of the recent platform-related studies have been theoretical studies on the characteristics of platform business status analysis, platform economy, and indirect network externalities of platforms. Therefore, this study comprehensively analyzed the success factors of Silicon Valley's business ecosystem proposed in previous studies, and at the same time analyzed the success factors extracted from stakeholders in the actual Silicon Valley platform business ecosystem. And based on these factors, an IPA analysis was conducted as a way to propose a success plan to stakeholders in the platform business ecosystem. As a result of the analysis, among the success factors collected through previous studies, manpower, capital, and challenge culture were identified as factors that are relatively well maintained in both importance and satisfaction in Silicon Valley. In the end, it can be seen that the creation of an environment and culture in which Silicon Valley can use it to challenge itself based on excellent human resources and abundant capital contributes the most to the success of Silicon Valley's platform business. On the other hand, although it is of high importance to Silicon Valley's platform corporate ecosystem, the factors that show relatively low satisfaction among stakeholders are 'learning and benchmarking among active companies' and 'strong ties and cooperation between members', and it is analyzed that interest and effort are needed to strengthen these factors in the future. Finally, the systems and policies necessary for market autonomous competition, 'business support service industry', 'name value', and 'spin-off start-up' were important factors in literature research, but the importance and satisfaction of these factors were lowered due to changes in the times and environment. This study has academic implications in that it comprehensively analyzes the success factors of Silicon Valley's business ecosystem proposed in previous studies, and at the same time analyzes the success factors extracted from stakeholders in the actual Silicon Valley platform business ecosystem. In addition, there is another academic implications that importance and satisfaction were simultaneously examined through IPA analysis based on these various extracted factors. As for academic implications, it is meaningful in that it contributed to the formation of the domestic platform ecosystem by providing the government and companies with concrete information on the success factors of the platform business ecosystem and the theoretical grounds for the growth of domestic platform businesses.

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