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Bivalvation Valvuloplasty for Common Atrioventricular Valve Regurgitation in Functional Single Ventricle; Early and Mid-term Results (기능적 단심설에서 공통방실판 역류의 판막성형술; 판막 이분성형술(bivalvation)의 조기 및 중기 결과)

  • Chang, Yun-Hee;Sung, Si-Chan;Kim, Seon-Hee;Lee, Hyoung-Doo;Ban, Ji-Eun
    • Journal of Chest Surgery
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    • v.42 no.5
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    • pp.597-603
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    • 2009
  • Background: Atrioventricular valve regurgitation in pediatric patients with a functional single ventricles (FSV) - has been known as one of the important risk factors for death and unfavorable long-term results after a Fontan operation. We evaluated early and mid-term results of bivalvation valvuloplasty in FSV patients. Material and Method: We retrospectively evaluated 11 patients with a functional single ventricle who underwent bivalvationvalvuloplasty between 1999 and 2007. The degree of common atrioventricular valve regurgitation (CAVVR) was determined by color Doppler echocardiography (regurgitation grade scoring, trivial; 1, mild; 2, moderate; 3, severe; 4). Mean age at valve surgery was $6.9{\pm}7.0$ months (median 4 months, 24 days$\sim$21 months)and mean body weight was $6.2{\pm}2.8\;kg$ ($3.1{\sim}11.3\;kg$). Nine patients had isomerism heart and two of them had TAPVC. The concomitant procedures were performed in all but one patient. Additional commissural closure was performed in 3 patients and commissural annuloplasty in another 3 patients. Result: There was one hospital death after. surgery. A 32-day old patient who had been preoperatively dependent on a ventilator died of air way and lung problems 4.3 months after pulmonary artery banding and bivalvation valvuloplasty. Mean follow-up duration was 40 months ($4.3{\sim}114$ months). Mean preoperative CAVVR score was $3.3{\pm}0.6$, which decreased to $1.9{\pm}0.7$ postoperatively (p<0.0001). This residual regurgitation slightly increased to $2.2{\pm}0.4$ (no statistical significance) after a mean follow-up of 1.4.3 months. Six patients (60%) required re-operations for residual regurgitation at a subsequent bidirectionalcavopulmonary shunt or Fontan operation. One patient with Ebsteinoid malformation of the right sided atrioventricular valve required valve replacement due to stenoinsufficiency. Another patient required edge-to-edge repair at the right sided AV valve (between the right mural leaflet and the bridging leaflets). The remaining 4 patients required additional suture placements between bridging leaflets with or without commissural annuloplasty. All survivor had trivial or mild CAVVR at the latest follow-up. Conclusion: Bivalvation valvuloplasty for CAVVR in FSV patients is. an effective and safe procedure. However, significant numbers of the patients have small residual regurgitation and require additional valve procedures at subsequent operations. Long-term observations to monitor progression of the CAVVR is mandatory.

Growth and Quality of Muskmelon (Cucumis melo L.) as Affected by Fruiting Node Order, Pinching Node Order and Harvest Time in Hydroponics Using Coir Substrate (코이어 배지를 이용한 멜론(Cucumis melo L.) 수경재배 시 착과 절위, 적심 절위 및 과실 수확시기에 따른 멜론의 생육 및 품질 특성)

  • Lim, Mi Young;Choi, Su Hyun;Choi, Gyeong Lee;Kim, So Hui;Jeong, Ho Jeong
    • Journal of Bio-Environment Control
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    • v.29 no.4
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    • pp.406-413
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    • 2020
  • This study was conducted to find out optimum fruiting node order, pinching node order, and harvesting time in hydroponics using coir substrates to produce high quality melon (Cucumis melo L.) fruit. Three plants per coir slab (100 × 20 × 10 cm) were planted for each treatment. Yamazaki standard nutrient solutions for melon were supplied with 1.8, 2.0, and 2.3 dS·m-1 at the early, middle (fruit enlargement step), and late growth stages, respectively. Two cultivars of 'PMR Dalgona' and 'Earl's Aibi' were used for fruiting node order and pinching node order experiments. Fruiting node treatments were conducted three replications (8-10 th, 11-13 th, and 14-15 th nodes) and pinching node treatments treated with three replications (18 th, 21 th, and 24 th nodes). Two cultivars of 'PMR Dalgona' and 'Earl's Crown' were used for fruit harvesting time experiment and treated with in four replications (45, 50, 55, and 60 days after fruiting). In growth characteristics, the leaf width and leaf area of 'PMR Dalgona' were the greatest 28.2 cm and 10,845 ㎠. Respectively, 11-13 th fruiting nodes or more. The node length of 'Earl's Aibi' was the longest by 147.6 cm at 11-13 th fruiting nodes. For fruit quality characteristics, the fruit weight of 'Earl's Aibi' at 11-13 th fruiting node fruiting was the greatest by 2.0 kg. The soluble solids content (SSC) of 'PMR Dalgona' was the highest by 14.5 °Brix at 8-10 th nodes in fruiting node orders and 14.5 °Brix at the 24 th pinching node order, respectively with significant difference. The SSC tends to increase in the same for both cultivars of 'PMR Dalgona' and 'Earl's Aibi' as the position of fruiting node was lower. The SSC and fruit weight of melon harvested at 55-60 days after fruiting was the best. From the results of this study, most of SSC tends to increase in the lower position of fruiting node order and the higher pinching node order, whereas the fruit weight shows a tendency of increasing with higher fruiting node. In addition, the SSC of fruit increased as the number of days after fruiting increased, and further research is needed for more various cultivars. In melon hydroponics using coir substrates, it is needed to figure out the characteristics of each cultivar to determine optimum fruiting node order, pinching node order, and fruit harvest time.

STUDIES ON THE VARIATION OF MICROFLORA DURING THE FERMENTATION OF ANCHOVY, ENGRAULIS JAPONICA (멸치 젓갈 숙성에 따른 미생물상의 변화에 대하여)

  • LEE Jong-Gap;CHOE Wi-Kyune
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.7 no.3
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    • pp.105-114
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    • 1974
  • Identification and change of microflora during the fermentation of anchovy Engraulis japonica, under the halophilic circumstance were investigated. The change of salinity and pH in meat and juice which decide the environment for microorganism and decomposition of nitrogenous compound which functions as a nutrient source were also discussed by measuring the content of total-N, amino-N, nonprotein-N, TMA and VBN, The fresh anchovy was mixed with rock salt (20 percent w/w) and stocked for six months. Through the fermentation lag phase of viable cells extended for 20 days that was obviously larger compared with other circumstances, hereafter increased to reach the maximum value of $5\times10^4$ total count per gram at 35 day stock. The stationary phase proceeded for 25 days. 540 strains were isolated and among them 11 genus of bacteria, 3 genus of yeasts, were identified and other 2 yeast strains of unidentified. At the initial stage of fermentation, Pseudomonas, and Helobacterium prevalently grew, at the middle stage, they disappeared rapidly and Pediococcus and yeasts completely dominated, where they are assumed to get directly involved with fermentation of fish, The PH value tended to decrease in the progress of fermentation and at 100 day stock it showed the minimum value of 5.5 to 5.6 in both meat and juice. The highest salinity of meat decreased to 18 percent, while in juice it decreased to 28 percent since 50 days stock. The content of total-N in meat gradually decreased to 2.8 percent, while in juice it increased to 2.3 percent at 100 day stock, However nonprotein-N was 1.8 percent and amino-N was 1.1 Percent. Since 100 days stock, the increasing rate of amino-M is too low it could be judged to entered the final stage of fermentation, In the first 20 days stock, the increase of VBN and TMA can be explained by the growth of putrefactive bacteria such as pseudomonas on the meat before salts penetrate into the fish meat, while reincrement after 100 days stock, is explained by decomposition of free amino acid due to the reactions of bacteria and enzymes.

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Short-term Variations in Community Structure of Phytoplankton and Heterotrophic Protozoa during the Early Fall Phytoplankton Blooms in the Coastal Water off Incheon, Korea (인천 연안의 초가을 식물플랑크톤 대증식기에 식물플랑크톤과 종속영양 원생동물 군집의 단주기 변동)

  • Yang, Eun-Jin;Choi, Joong-Ki
    • Ocean and Polar Research
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    • v.29 no.2
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    • pp.101-112
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    • 2007
  • In order to examine the short-term variations of phytoplankton and heterotrophic protozoa community structures with bloom events, water samples were collected every other day at one site in the coastal water off Incheon, Korea, from August 15-September 30, 2001. $Chlorophyll-{\alpha}$ concentrations varied widely from 1.8 to $19.3\;{\mu}g\;l^{-1}$ with the appearances of two major peaks of $Chlorophyll-{\alpha}$ concentration during the study period. Size-fractionated $Chlorophyll-{\alpha}$ concentration showed that net-size fraction ($>20\;{\mu}m$) comprised over 80% of total $Chlorophyll-{\alpha}$ during the first and second bloom periods, nano-size fraction ($3{\sim}20\;{\mu}m$) comprised average 42% during the pre- (before the first bloom) and post-bloom periods (after the second bloom), and pico- size fraction ($<3\;{\mu}m$) comprised over 50% during inter-bloom periods (i.e. between the first and second bloom periods). Dominant phytoplankton community was shifted from autotrophic nanoflagellates to diatom, diatom to picophytoplankton, picophytoplankton to diatom, and then diatom to autotrophic nanoflagellates, during the pre-, the first, the inter, the second, and the post-bloom periods, respectively. During the blooms, Chaetoceros pseudocrinitus and Eucampia zodiacus were dominant diatom species composed with more than 50% of total diatom. Carbon biomass of heterotrophic protozoa ranged from 8.2 to $117.8\;{\mu}gC\;l^{-1}$ and showed the highest biomass soon after the peak of the first and second blooms. The relative contribution of each group of the heterotrophic protozoa showed differences between the bloom period and other periods. Ciliates and HDF were dominant during the first and second bloom periods, with a contribution of more than 80% of the heterotrophic protozoan carbon biomass. Especially, different species of HDF, thecate and athecate HDF, were dominant during the first and the second bloom periods, respectively. Interestingly, Noctiluca scintillans appeared to be one of the key organisms to extinguish the first bloom. Therefore, our study suggests that heterotrophic protozoa could be a key player to control the phytoplankton community structure and biomass during the study period.

Surgical outcome of severe pulmonary arterial hypertension secondary to left-to-right shunt lesions (심한 폐동맥 고혈압을 동반한 좌우 단락 질환 환자의 수술 후 경과)

  • Lee, Cha Gon;Jeong, Su-In;Huh, June;Kang, I-Seok;Lee, Heung Jae;Yang, Ji-Hyuk;Jun, Tae Gook
    • Clinical and Experimental Pediatrics
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    • v.53 no.2
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    • pp.195-202
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    • 2010
  • Purpose : Despite recent advances in pulmonary hypertension management and surgery, appropriate guidelines remain to be developed for operability in congenital heart disease with pulmonary artery hypertension (PAH). Our aim was to evaluate clinical outcomes of patients with severe PAH who underwent surgical closure of left-to-right shunt lesions (LRSL) on the basis of pulmonary reactivity. Methods : We retrospectively reviewed 21 patients who underwent surgical closure of LRSL with severe PAH (${\geq}8$ Wood unit) from January 1995 to April 2009. The median age at operation was 26 years. Atrial septal defect, ventricular septal defect (VSD), VSD and patent ductus arteriosus (PDA), and PDA was present in 11, 4, 4, and 2 patients, respectively. Results : Operability was based on vasoreactivity of PAH. Of the 21 patients, 5 showed response to pulmonary vasodilator therapy and 8 showed vasoreactivity after balloon occlusion of defects. The remaining 8 patients were considered operable because of significant left-to-right shunt (Qp/Qs ${\geq}1.5$). Five patients underwent total closure of defects and 16 were left with small residual shunts. The median follow-up duration was 32 months. There was no significant postoperative mortality or morbidity. Systolic pulmonary artery pressure (PAP) decreased in all but 2 patients. All patients except 1 showed improvement of New York Heart Association functional class. Conclusion : Closure of LRSL in patients with severe PAH on the basis of pulmonary vasoreactivity seems reasonable. PAP and clinical symptoms improved in most patients. Further research is needed for the evaluation of long-term results.

Effect of Fertigation with Indigenous Microorganism and EM on Soil Chemical and Microbial Properties and Growth of Cherry Tomatoes (토착미생물과 EM 활용 액비 처리가 방울토마토의 토양 화학성과 미생물상 및 생장에 미치는 영향)

  • Choi, Hyun-Sug;Jung, Ji-Sik;Kuk, Yong-In;Choi, In-Young;Jung, Seok-Kyu
    • Journal of the Korea Organic Resources Recycling Association
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    • v.27 no.4
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    • pp.15-24
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    • 2019
  • The study was compared for soil chemical and microbial properties as well as growth of the cherry tomato (Lycopersicon esculentum var. cerasiforme) plants environmentally friendly gown for 3 years and 5 years, which had been fertigated with homemade liquid fertilizer (LF) with indigenous microorganism as an additional fertilizer. Treatment included LF with indigenous microorganism for 3 years (3-year IM-LF) and for 5 years (5-year IM-LF), with an effective microorganism for 10 years (EM-LF), which had been applied with 1,000 times of dilution in the farmhouse. IM-LF and EM-LF materials had increased pH pattern for 16 weeks, in particular for increase of 1.2 for EM-LF. IM-LF material contained slightly higher EC but similar level of 0.2 dS/m to EM-LF. For a pot experiment in the greenhouse, IM-LF treatment increased root dry weight of the cherry tomato plants. In the farmhouse experiment, IM-LF treatment increased to 7.5 of soil pH and 8.4 dS/m of EC, indicating high salt accumulation. EM-LF treatment increased to 62 g/kg of soil OM, which would have affected concentrations of macro essential nutrients, including T-N in the soil. However, the optimum soil chemical levels for growth of cherry tomato plants were observed on the IM-LF plots. EM-LF treatment increased number of bacteria and actinobacteria in the soil. EM-LF treatment increased concentrations of macro essential nutrients in the plants, except for P, with similar nutrient concentrations observed between 3-year IM-LF and 5-year IM-LF-treated plants. Leaf SPAD and PS II levels decreased in the plants treated with 3-year IM-LF. EM-LF treatment increased leaf width and length, number of leaves, canopy area, plant height, and stem diameter in the mid-term stage of growth, which were not significantly different between the treatments. EM-LF treated-plants had two times higher leaf dry weight than those of values observed on the IM-LF plants, which was the opposite result observed on the number of fruit.

Studies on Restoration of Forest-Floor Vegetation Devastated by Recreational Trampling (I) -Seeding, Fertilizing and Soil Surface Treatment Effect on Restoration of Forest-Floor Vegetation- (답압(踏壓)으로 훼손(毁損)된 임간나지(林間裸地)의 임상식생복원(林床植生復元)에 관한 연구(硏究)(I) -임상식생복원(林床植生復元)에 미치는 파종(播種), 시비(施肥) 및 표토처리효과 (表土處理效果)-)

  • Oh, Koo Kyoon;Woo, Bo Myeong
    • Journal of Korean Society of Forest Science
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    • v.81 no.1
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    • pp.53-65
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    • 1992
  • For elucidating effective methods of restoration of forest recreational sites where management goals are maintaining naturalness and conserving natural ecosystem, seeding, fertilization and soil surface treatment were used for four years at the devastated forest-floor. For restoration of forest-floor vegetation, factorial experiment was used with a split plot design(main plot : fertilization, subplot : soil surface${\times}$seeding) and a randomized complete block design (fertilization${\times}$seeding) at the Kwanaksan Aboretum, Anyang, Kyonggido. Results were summarized as follows : Soil surface softening with tipping and ripping and straw-mat mulching (70% coverage) treatment was effective on germination, survival and growth of seeded vegetation at devastated forest-floor. Especially, straw-mat mulching treatment was effective on soil surface stabilization and seedling's survival at eroded soil surface, while complete soil surface softening treatment was effective on germination, survival and early growth of tree species of late-successional series. Introducing seeds of native species of pioneer or early-successional series, with good growth capability in barren soil was effective on rapid restoration in devastated forest-floor with its soil surface previously compacted and its surviving seeds washed away. When the seeding and straw-mat mulching after partial soil surface softening with tipping and ripping treatment were employed, it took about three years to restore the devastated forest-floor where surface erosion had been undertaken for an extended period of time and where naturally surviving seeds of native species had been washed away. Softening treatment of soil surface was effective for about two years, and seeding and soil surface treatment increased number of seedlings and improved soil surface environment through fixing of movement of the fallen leaves. Fertilizing effect was not oberserved, mainly due to seeding exposure and poor physical condition including soil surface erosion, low soil water potential and drought, etc, at the field experimental site. However, application of nitrogen and phosphate fertilizers was effective on seedling survival of the species in late-successional series, while lime application adversely affected the seedling survival.

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Effect of Reused Cocopeat Substrate on Growth and Yield of Summer-cultivated Paprika in EC-based Recycling Hydroponic Cultivation (EC기준 순환식 수경재배에서 코크피트배지 재사용이 여름작형 파프리카의 생육 및 수량에 미치는 영향)

  • Jang, Dong-Cheol;Choi, Ki-Young;Yeo, Kyung-Hwan;Kim, II-Seop
    • Journal of Bio-Environment Control
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    • v.26 no.2
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    • pp.100-107
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    • 2017
  • This experiment was carried out to analyze the effects of substrate reuse on the growth and yield of summer paprika in cyclic hydroponics. The test group was divided into a new coco slab, one year reused coco slab two year reused coco slab based on 30% nutrient solution reuse, and was performed from April 18 to November 31, 2016 for 30 weeks. As a result, plant height of early growth was that the 2 year reused slab was longer than the new slab but the final growth period was 56.58 cm shorter. First group flower position was that reused slab was shorter by 2.92 cm than the new slab and the second group flower position was 0.31 cm long. The relative internode length of early growth, when the reused slab was used, the imbalance in the late growth stage was increased compared with the use of the new slab. The number of growth nodes in the 1 and 2 year reused slab was the smallest with 27.4 nodes. However, the number of harvested nodes did not show the difference in the test group, and the ratio of harvested that the 2 year reused slab was the highest at 26.8%. The ratio of unmarketable fruit tended to increase as the growth progressed. Fresh weight was 227.7g for new slab, 219.2g for 2 year reused slab and 21.2g for 1 year reused slab. The dry weight of the new slab increased with the reuse of the slab. It was 17.13g for new slab, 18.26g for 1 year reused, and 19.28g for 2 year reused. The average water content of the entire growth period was smaller as the slab was reused, and the 1 year reused slab was about 20g less than the 2 year reused slab. This trend was steadily occurring throughout the entire growing season. Especially, the reused slab for 1 year was less than 60g after 3 groups compared to other test groups. In conclusion, If will control seriously occurrence of unmarketable fruits by weakening after medium growth in summer-cultivated paprika in EC-based recycling hydroponic cultivation with reused cocopeat substrate, It is not what I have to worry that decrease of the yield and deterioration of the quality due to the change of physical and chemical properties of the slab and the pathogenic bacteria infection.

An Effect of the Selection of Excellent Design Product on the Business Performance in the Start-up: Focusing on 2013, 2014 and 2015 Design Awarded Companies (우수디자인제품 선정이 창업기업 경영성과에 미치는 영향: 2013년, 2014년, 2015년 우수디자인제품 선정기업들 중심으로)

  • Yoo, joung houn;Bae, byung Yun;Jeon, Ki suk
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.13 no.4
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    • pp.211-216
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    • 2018
  • This study was intended to analyze the effects of the selection of excellent design product by the KIDP(Korea Institute of Design Promotion) on the business performance of the company focused on the start-up with relatively low competitiveness. According to the statistics of KIDP in 2013, a design accounted for 27.53% of the factors affecting the sales of products and a design was the most important factor among the factors affecting the sales of products for the small sized company in terms of the scale of company. In addition, looking at the trend by industry in the data collected for this study, the technology-based industry showed a relatively higher growth rate than the retail industry and other industries. In this study, the author surveyed 186 companies of the companies that recognized the importance of design in difficult management conditions and received excellent design product certificate from KIDP(2013, 2014 and 2015) and empirically verified whether there was any difference in business performance between the start-ups with a business history of less than 7 years and the ongoing firms with a business history of more than 7 years. To evaluate the value of design, we used analytical method of measuring related values by comparison between groups. In addition, we also analyzed the difference in business performance(sales) between manufacturing companies, where the role of design was relatively large, and non-manufacturing companies among companies that received the excellent design product certificate. We have established a study hypothesis that the selection of excellent design product by the KIDP would have more positive effect on the business performance(sales) of the start-up compared to the ongoing firm, and conducted an empirical analysis by comparing both the year before and the year after the selected year. As a result, we found that the selection of excellent design product by the KIDP has a positive effect on the business performance of the start-up, and the selection of excellent design product has a significant effect on the difference in business performance between manufacturing and non-manufacturing companies. This study was conducted in the hope that the government actively supports the design-related policies so that the selection of excellent design product become an important indicator of the business performance of the start-up, and thus the design management will be a way to enhance the competitiveness of the start-up.

Cord blood IL-10, IL-12 in preterm newborns as predictors of respiratory distress syndrome and bronchopulmonary dysplasia (호흡곤란증후군과 기관지폐이형성증 예측 인자로서의 미숙아 제대혈 IL-10, IL-12)

  • Park, Jee Yoon;Kim, Ji Young;Cho, Soo Jin;Kim, Young Ju;Park, Hye Sook;Ha, Eun Hee;Park, Eun Ae
    • Clinical and Experimental Pediatrics
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    • v.50 no.3
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    • pp.248-254
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    • 2007
  • Purpose : Inflammation plays a major role in the pathogenesis of RDS and BPD in the immature lung. We investigated the possible role of IL-10 and IL-12 in the cord blood of preterm newborns with RDS or BPD. Methods : Forty preterm newborns whose mothers received antenatal care at Ewha Womans University Mokdong Hospital between January 2003 to June 2005, and agreed to testing their cord blood samples were enrolled. The gestational ages were below 34 weeks. Cord blood level of IL-10 and IL-12 were determined by ELISA. We separated the patients into 2 groups (RDS group and non-RDS group, BPD group and non-BPD group) and compared the cytokine levels and clinical records of the groups. Results : Cord blood IL-10 level showed a significant inverse correlation with gestational age and birth weight (P=0.001, P=0.005). Preterm infants with RDS showed higher IL-10 level (1.0 vs 0.1 pg/mL; P=0.001) in the cord blood than those without RDS. The differences remained statistically significant after correction for the effect of gestational age between both preterm groups. Despite similar cord blood IL-10 levels, preterm infants with BPD showed no significant difference with those without BPD. Conclusion : Cord blood IL-10 levels are increased in preterm infants which may be due to the immuno-suppression occurring during pregnancy and to fetal immaturity because these levels are inversely correlated with the gestational age. So, Cord blood IL-10 level can be used as the predictor of RDS.