• Title/Summary/Keyword: 주름깊이

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Anti Photoaging Effects of Hyaluronic Acid following Oral Administration in SKH-1 Hairless Mice (SKH-1 Hairless Mice에서의 히알루론산 경구 투여를 통한 피부 광노화 개선 효과)

  • Lee, Sung-jin;Seo, YoonHee;Yun, Min-kyu;Yu, Heui-jong;Choe, Soo-Young
    • The Korean Journal of Food And Nutrition
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    • v.28 no.6
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    • pp.941-946
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    • 2015
  • Photoaging is the main extrinsic aging factor that is induced due to UVB. Many studies have revealed that application of hyaluronic acid to the skin is effective in healing photoaging. However, the effect of hyaluronic acid through oral administration is unclear. The aim of this research was to investigate the effect on skin photoaging after oral administration of hyaluronic acid. During a ten week study, hyaluronic acid was fed to hairless mice, which were illuminated by UV radiation. After ten weeks, wrinkle indicator and histological changes were determined. Compared with the control group, the sample group had a decrease in wrinkle depth, thickness, and number. Especially, the HA 160 mg/kg group had a similar value of wrinkle depth ($19.44{\pm}0.75{\mu}m$), number ($654.00{\pm}98.34$), and thickness ($1.35{\pm}0.08mm$), when compared with the RA (retinoic acid) group ($19.28{\pm}0.95{\mu}m$, $653.57{\pm}83.54$, and $1.34{\pm}0.07mm$ respectively). Also, the treated group showed improved elastosis and decreased collagen degradation resulting from UV irradiation. Thus, we can conclude that hyaluronic acid has a positive effect in improving skin photoaging induced by UV radiation. Hyaluronic acid therefore has the potential to be an ingredient in skin health function foods.

Verification of wrinkle improvement effect by animal experiment of suture for skin wrinkle improvement by applying CO2 gas and RF radio frequency (CO2 gas와 RF 고주파를 적용한 피부 주름 개선용 봉합사 동물 실험에 따른 주름 개선 효과 검증)

  • Jeong, Jin-Hyoung;Shin, Un-Seop;Song, Mi-Hui;Lee, Sang-Sik
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.13 no.3
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    • pp.226-234
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    • 2020
  • As the average life expectancy of human beings is extended in addition to the entry of the aging society, there is a tendency for the interest in the appearance of men and women in modern society to increase. The most external judgment of human aging is the wrinkles on the facial skin. People are undergoing various procedures to have clean, wrinkled, and resilient healthy skin. Many thread lifting procedures are being implemented because they tend to want simple and effective procedures during the procedure. In this study, in order to improve lifting effect in thread lifting, animal experiments were conducted to confirm the improvement of wrinkles by injecting RF high frequency and CO2 gas into existing PDO suture procedures. The experimental groups consisted of natural aging groups, PDO treatment groups, groups with RF high frequency in PDO procedures, groups with CO2 gas injected into PDO procedures, and groups with CO2 gas and RF injected simultaneously into PDO procedures. The individuals in the natural aging group had an average wrinkle depth of 0.408mm before the procedure, and the average wrinkle depth of the 10th week was 0.68mm. The depth of wrinkles in the PDO treatment group averaged 0.384mm before the procedure, and 0.348mm on the 10th week after the procedure. The average crease depth of pre-procedure objects injected with RF high frequency in PDO was 0.42mm, and the average crease depth for 10 weeks was 0.378mm. The average crease depth of the CO2 gas injected into the PDO was 0.4mm before the procedure, and the average crease depth was reduced to 0.332mm in the 10th week after the procedure. On average, the number of objects injected with CO2 gas and RF high frequency in the PDO procedure decreased to 0.412mm before and 0.338mm in the 10th week after the procedure. The procedure of injecting CO2 gas and RF into the PDO suture showed the highest reduction rate of 17.96%.

A Study on Development of Wrinkle Evaluation Software and Verification of Skin Wrinkle Improvement of Cog Suture (주름 평가 소프트웨어 개발과 Cog형 봉합사의 피부 주름 개선 검증에 관한 연구)

  • Jeong, Jin-Hyoung;Lee, Sang-Sik
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.12 no.4
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    • pp.336-342
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    • 2019
  • With the entry of an aging society, the average life span of accreditation has been extended. Therefore, interest in the appearance of men and women in modern society has increased. It is the wrinkles of the face that can judge the most outwardly. People tend to have various kinds of treatments to have a clean, wrinkle-free and resilient healthy skin regardless of sex. There is a lot of practice of lifting procedures in one of the procedures. A suture using a melting thread is a method of lifting by squeezing it into the skin as a non-incision type centering on a region where the thread can be fixed in the skin by injecting it into the subcutaneous fat layer. To evaluate the lifting efficacy of Cog - type suture for the improvement of skin wrinkles, preclinical experiments were conducted. We developed a wrinkle evaluation program using Labview. Data from preclinical experiments were used at 8 weeks after suturing. The average wrinkle depth was 415.6 mm in the control group. At 8 weeks, the depth of wrinkles was deepened to 888.3mm due to the aging process of the control group. On the other hand, the depth of the wrinkles before surgery was 640.3 mm in the suture group. It was confirmed that the depth of wrinkles decreased to 566.5mm at 8th week after the suture operation.

Improving Over-segmentation of Skin Wrinkle Detection by Watershed Algorithm (Watershed 알고리즘의 피부 주름 과분할 개선에 관한 연구)

  • Lee, Kyung-Seung;Choi, Young-Hwan;Hwang, Eenjun
    • Proceedings of the Korea Information Processing Society Conference
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    • 2010.11a
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    • pp.697-700
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    • 2010
  • 피부 이미지의 여러 가지 특징들 중 주름은 피부의 상태를 판단하는 중요한 요소이다. 따라서 주름을 추적하기 위해 확대경으로 촬영된 원본 이미지에서 질감 대비 증가, 노이즈 제거 등의 전처리 과정을 수행한 후 Watershed 알고리즘을 이용하여 주름을 선분으로 표현하였다. 이렇게 생성된 주름의 깊이, 너비, 길이 등은 피부 분석 시 특징 정보로 이용할 수 있다. 또한 주름과 주름이 연결되어 이루는 다각형을 논문에서는 셀(Cell)이라고 정의하는데 그것의 크기나 개수 같은 정보도 추출할 수 있게 된다. 그러나 주름으로 만들어진 셀들은 실제와 다르게 과분할 되는 경향을 보인다. 과분할 된 셀들은 잘못된 정보를 제공하기 때문에 피부 상태를 판단하는 결과의 정확도를 떨어뜨린다. 본 논문에서는 이러한 문제점을 인지하고 차후 정확한 셀 정보를 획득하기 위한 확장성 측면에서 각 셀들을 개체화시키고 과분할 된 셀을 검출하는 방법을 제안한다.

A Low Cost 3D Skin Wrinkle Reconstruction System Based on Stereo Semi-Dense Matching (반 밀집 정합에 기반한 저가형 3차원 주름 데이터 복원)

  • Zhang, Qian;WhangBo, Taeg-Keun
    • Journal of Internet Computing and Services
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    • v.10 no.4
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    • pp.25-33
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    • 2009
  • In the paper, we proposed a new system to retrieve 3D wrinkle data based on stereo images. Usually, 3D reconstruction based on stereo images or video is very popular and it is the research focus, which has been applied for culture heritage, building and other scene. The target is object measurement, the scene depth calculation and 3D data obtained. There are several challenges in our research. First, it is hard to take the full information wrinkle images by cameras because of light influence, skin with non-rigid object and camera performance. We design a particular computer vision system to take winkle images with a long length camera lens. Second, it is difficult to get the dense stereo data because of the hard skin texture image segmentation and corner detection. We focus on semi-dense stereo matching algorithm for the wrinkle depth. Compared with the 3D scanner, our system is much cheaper and compared with the physical modeling based method, our system is more flexible with high performance.

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Development of Non-contact Image Measuring Technique for Evaluating Micro-relief (미세주름 측정을 위한 비접촉식 영상측정기술의 발전)

  • Kim, Nam-Soo;Kim, Yong-Min
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.31 no.3 s.52
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    • pp.253-257
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    • 2005
  • Assurance of the objectivity and reproducibility is a major key point in wrinkle measurement used for evaluating the degree of skin aging. The measurement of relief is quickly converted to a non-contact method, of which tools or instruments do not come in contact with skin directly, to minimize the artificial effects which influence the shape or depth of the relief. Here, we showed how wrinkle measurement techniques have been changed briefly and compared PRIMOS and replica method in the point of view of measurement principle and features, the former is non-contact fringe projection tool and the latter is contact type of the method.

The Uplift Capacity of Plane and Corrugated Piles for Pipe Frame Greenhouse (파이프 골조온실의 민말뚝과 주름말뚝의 인발저항력)

  • Yong Cheol Yoon;Won Myung Suh;Jae Hong Cho
    • Journal of Bio-Environment Control
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    • v.10 no.3
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    • pp.148-154
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    • 2001
  • The uplift capacity of a pile for improving the wind resistance of the 1-2 W type plastic film pipe on greenhouses was tested using the plane and corrugated piles with various shapes and diameters. First, the resistant uplift capacity was measured by using the uplift loading on plane piles. As the uplift loading on plane piles increased, the resistant uplift capacity also increased until the loading was reached to ultimate uplift capacity. After ultimate uplift capacity was appeared the uplift displacement, the uplift capacity was decreased gradually. Secondly, the resistant uplift capacity was measured by using the uplift loading on corrugated piles. After the uplift capacity was reached the uplift displacement, the uplift capacity was continually increased or decreased. In general, the ultimate uplift capacity was independent of pile shapes, pile diameter length, and embedded pipe depth. However, the ultimate uplift capacity of a corrugated pile was twice more than that of a plane pile without regard to its diameter and embedded depth. The ultimate uplift capacity per unit pile area was increasing in deeper embedded depth. However, the longer a pile diameter was, the less ultimate uplift capacity. The uplift capacity of a plane pile, used in conjunction with the design wind velocity (26.9m.s$^{-1}$ ) of the project area, was unsatisfiable without regard to diameters and embedded depths of piles, while most of corrugated piles were well appeared uplift capacity under various experimental conditions.

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Ultrasound Imaging for Position of the Sciatic Nerve Division in Korean Female (한국 여성에서 좌골 신경 분지 위치에 대한 초음파 영상)

  • Nam, Il Hyun;Yeo, Eui Dong;Yu, Ji Soo;Lee, Jun Ho;Lee, Young Koo
    • The Journal of Korean Orthopaedic Ultrasound Society
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    • v.7 no.1
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    • pp.28-32
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    • 2014
  • Purpose: We aim to determine sciatic nerve bifurcation location and depth at the level of the popliteal fossa in Korean female. Materials and Methods: Thirty three subjects were enrolled in Korean female. M-turbo ultrasound system (SonoSite, bothell, WA, USA)with 38 mm high frequency linear array transducer, 13-6 MHz probe was used for ultrasound measurements. With subject lying prone, the location of the sciatic nerve in relation to the popliteal crease and skin to nerve distance were assessed via ultrasound. Analyses were performed with SAS version 9.3 using multiple linear regression. Results: Thirty three subjects were enrolled. Distance from the popliteal crease to the sciatic nerve was 4.5-7.5 (mean 5.7 cm), and the depth of the sciatic nerve from the skin was 1.8-3.2 (mean 2.4 cm). Multiple linear regression for the usefulness of the model has a p value of 0.036, shows between weight and depth. Conclusion: We show that variability exists for sciatic nerve bifurcation location in Korean female, The success rate is creased if consider the relations between weight and depth when performs sciatic nerve block in Korean female. In our study, a sciatic nerve block is recommend that performed 7.5 cm proximal to the crease in the popliteal fossa.

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Evaluation of Age-dependent Crow′s Feet in Korean Women (한국여성의 연령별 눈가 주름의 정량 분석)

  • 이미영;김은정;이희경;서영경;이민선;고재숙
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.30 no.1
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    • pp.85-91
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    • 2004
  • In this study, we evaluated the crow's feet of 152 Korean women by using visual assessment established by our research group and mechanical assessment, Skin Visiometer SV 600. The volunteers were divided into 3 groups according to age; the group I of 30's was 43, the group II of 40's was 75, the group III of 50's was 34. The wrinkle score by visual assessment showed tendency to increase according to age and was statistically significant different among those three age groups (P 〈 0.05). But there was no significant difference between the left and the right of crow's feet. The 5 wrinkle parameters (RI, R2, R3, R4, R5) of mechanical assessment varied as age and the Rl, R4, and R5 showed statistically significant difference among three age groups (P 〈 0.05). However there was no significant difference between the left and the right of crow's feet. The volunteers were divided into 3 groups according to wrinkle score; (0-3 grade for group A, 4-6 grade for group B, 7-9 grade for group C). Only R4 and R5 showed significant difference between group A and group C (P 〈 0.05). It was suggested that visual scoring criteria applied in this study was related to R4 and R5 and was useful in investigating in fine wrinkles.

Development of Anti-Aging Products (Anti-Wrinkle) like Epidermal Growth Factor(EGF) Materials using Supercritical Heat-Treated Extract Radish (초임계 열처리된 무 성분을 이용한 상피세포성장인자(EGF) 유사소재 개발 및 광노화(주름개선) 효과)

  • Kim, Hyun Kyoung
    • The Journal of the Convergence on Culture Technology
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    • v.4 no.3
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    • pp.197-207
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    • 2018
  • The radish skin and radish greens (mucheong) are an edible part of the radish. But they are removed before eating the radish and used as a byproduct or an animal feed material because of their tough and rough texture. This study was conducted to investigate the effect of supercritical heat-treated radish-extract on UV-induced Hos: HRM-2 wrinkled mouse animal model on anti-aging wrinkles. Supercritical heat-treated radish-extract was applied on the back of seven-weeks old HRM-2 mice. The effect of HRE on skin thickness, elasticity and wrinkle formation of the mice was observed by using UVB lamp to induce melanogenesis and wrinkle formation. As the result, increased depth of wrinkles was observed in the negative control group in comparison to the normal group. In contrast, decreased depth of wrinkles was observed in the radish-extract-free group compared to the negative control group. In the study of the effect of radish-extract on wrinkle-formation related gene expression and protein what protein expression, MMP-2 and MMP-2 gene expression significantly increased in the negative control group compared to the normal group. The gene expression reduced independence to the mass of radish-extract treated. Similar to quantitative results of mRNA expression, the expression of MMP-2 protein increased as a result of UVB-irradiation. The MMP-2 expression was inhibited in dependence to the mass of radish-extract treated. In conclusion, the supercritical heat-treated radish-extract has an effect on improving skin wrinkles not only when it is applied to the skin but also when orally ingested. Thus, it can be effectively used as a composition to health functional products. Thereafter, we can also conclude that radish, a food that does not show any side-effects even upon long-term intake, can reduce wrinkle formation as well as improve skin elasticity when taken regularly for a long period.