• Title/Summary/Keyword: 주기조절

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The Effect of Microbending on Photonic Crystal Fiber (광자결정 광섬유의 마이크로벤eld 영향)

  • 문대승;김진채;엄주범;백운출;이병하
    • Proceedings of the Optical Society of Korea Conference
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    • 2002.07a
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    • pp.168-169
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    • 2002
  • 일반적인 광섬유가 실리카로 만들어진 클래딩과 이보다 약간 굴절률이 높은 코어로 구성되어 있는 것과는 달리 광자결정 광섬유(photonic crystal fiber 또는 다공성 광섬유(holey fiber))는 코아와 클래딩이 순수 실리카로 구성되어 있다 클래딩의 효과를 주기 위해 광섬유 축을 따라서 규칙적인 공기구멍 다발을 형성하여 준다. 광자결정 광섬유는 특이한 광학적 특성 때문에 최근에 활발히 연구되어 지고 있다. 공기구멍의 구조를 조절함으로써 넓은 파장 영역에서 단일 모드로 진행하고(1), 아주 큰 분산을 갖게 할 수 lT고, hem 반경을 조절 할 수 있으며, 특이한 분산 특성과 이의 조절이 가능하다. (중략)

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New Installation Method of House Bend (하우스 밴드의 설치방법 개발)

  • 김진한;김형준;유복상
    • Proceedings of the Korean Society for Bio-Environment Control Conference
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    • 1999.11a
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    • pp.86-88
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    • 1999
  • 비닐하우스에 있어서 외피복 비닐은 매년 혹은 몇 년에 한번씩 갈아 씌우게 된다. 이때에는 하우스 밴드를 풀어서 다시 매야 하는데 현재로서는 적당한 방법이 없다. 돌, 피트병을 묶어 던지거나 장갑 속에 돌을 넣고 던지는데 이때에 하우스에 상처를 주기 쉽고 반대편의 사람이 맞으면 해를 입으며 무게를 조절할 수 없어서 넘기는데 애로가 많다. 그러므로 힘이 적게 들고 간편하며 작업속도가 빠른 방법을 찾고자 본 실험을 실시하였다. (중략)

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The COP9 Signalosome Network in Eukaryotic Microorganisms (진핵 미생물에서의 COP9 signalosome의 역할)

  • Cheon, Yeongmi;Lee, Soojin
    • The Korean Journal of Mycology
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    • v.41 no.1
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    • pp.1-8
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    • 2013
  • COP9 signalosome (CSN), which is originally identified as the regulator of the photomorphogenic development in plant, is highly conserved protein complex in diverse eukaryotic organisms. Most eukaryotic CSN complex is composed of 8 subunits, which is structurally and functionally similar to the lid subunit of 26S proteasome and eIF3 translation initiation complex. CSN play important functions in the regulation of cell cycle and checkpoint response by controlling Cullin-Ring E3 ubiquitin ligases (CRL) activities. CSN exhibits an isopeptidase activity which cleaves the neddylated moiety of cullin components. In fission yeast, S-phase cell cycle progression was delayed and the sensitivity to g-ray or UV was increased in CSN1 and CSN2 deletion mutants, indicating that yeast CSN is also involved in the checkpoint regulation. CSN in fungal system more closely resembles that of the higher organisms in the structure and assembly of their components. Functionally, CSN is associated with the regulation of conidiation rhythms in Neurospora crassa and the sexual development in Aspsergillus nidulans. Recent studies also revealed that CSN functions as an essential cell cycle regulator, playing key roles in the regulation of DNA replication and DNA damage response in Aspergillus. Overall, CSN of microorganisms, such as fission yeast and fungi, share functionally common aspects with higher organisms, implying that they can be useful tools to study the role of CSN in the CRL-mediated diverse cellular activities.

Some Aspects of Physiology of Estrous Cycle in Goats (산양의 발정주기의 생리에 관한 고찰)

  • 박충생
    • Journal of Embryo Transfer
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    • v.1 no.1
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    • pp.59-68
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    • 1986
  • 산양의 발정주기의 생리와 조절에 관한 최근 연구 보고들과 한국 재래산양의 대한 이들 연구 결과를 모아 고찰하였다. 온대지역에서 산양의 번식계절은 분명하나 한국재래산양의 경우는 비번식계절이 비교적 짧거나 계절적 무발정율이 낮은 편이며, 비번식계절에는 기능적 황체가 유지되지 않는다. 한국재래산양의 발정주기와 발정지속기간은 타품종과 비슷하며, 발정지속기간의 반복력은 매우 낮으며, 발정주기중의 progesterone과 estradiol-17$\beta$의 소장을 규명하였다. 한국재래산양의 경우 황체기에 PGF2 1-3mg을 투여하면 항체퇴행을 유기할 수 있으나 주기중의 투여시기에 따라 투여후 발정개시 시간에 차이가 있었다. 그리고 pro-gesterone priming후 PGF$\alpha$를 투여함으로써 효과적인 발정동기화를 이룰 수 있었다. 분만후 1개월경과 유상후 12일경에 발정이 재귀되었으며, 첫 발정 후 80%의 산양에서 5-7일의 단발정주기를 나타냈으며, 대부분의 과배란유기 산양에서도 단발정주기를 나타냈는데 이는 황체의 조기퇴행 때문이었다. 초발정후 3-5일에 GnRH를 연속 주사하면 단발정주기의 발생율이 유의적으로 감소되었다.

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Usefulness of Gated RapidArc Radiation Therapy Patient evaluation and applied with the Amplitude mode (호흡 동조 체적 세기조절 회전 방사선치료의 유용성 평가와 진폭모드를 이용한 환자적용)

  • Kim, Sung Ki;Lim, Hhyun Sil;Kim, Wan Sun
    • The Journal of Korean Society for Radiation Therapy
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    • v.26 no.1
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    • pp.29-35
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    • 2014
  • Purpose : This study has already started commercial Gated RapidArc automation equipment which was not previously in the Gated radiation therapy can be performed simultaneously with the VMAT Gated RapidArc radiation therapy to the accuracy of the analysis to evaluate the usability, Amplitude mode applied to the patient. Materials and Methods : The analysis of the distribution of radiation dose equivalent quality solid water phantom and GafChromic film was used Film QA film analysis program using the Gamma factor (3%, 3 mm). Three-dimensional dose distribution in order to check the accuracy of Matrixx dosimetry equipment and Compass was used for dose analysis program. Periodic breathing synchronized with solid phantom signals Phantom 4D Phantom and Varian RPM was created by breathing synchronized system, free breathing and breath holding at each of the dose distribution was analyzed. In order to apply to four patients from February 2013 to August 2013 with liver cancer targets enough to get a picture of 4DCT respiratory cycle and then patients are pratice to meet patient's breathing cycle phase mode using the patient eye goggles to see the pattern of the respiratory cycle to be able to follow exactly in a while 4DCT images were acquired. Gated RapidArc treatment Amplitude mode in order to create the breathing cycle breathing performed three times, and then at intervals of 40% to 60% 5-6 seconds and breathing exercises that can not stand (Fig. 5), 40% While they are treated 60% in the interval Beam On hold your breath when you press the button in a way that was treated with semi-automatic. Results : Non-respiratory and respiratory rotational intensity modulated radiation therapy technique absolute calculation dose of using computerized treatment plan were shown a difference of less than 1%, the difference between treatment technique was also less than 1%. Gamma (3%, 3 mm) and showed 99% agreement, each organ-specific dose difference were generally greater than 95% agreement. The rotational intensity modulated radiation therapy, respiratory synchronized to the respiratory cycle created Amplitude mode and the actual patient's breathing cycle could be seen that a good agreement. Conclusion : When you are treated Non-respiratory and respiratory method between volumetric intensity modulated radiation therapy rotation of the absolute dose and dose distribution showed a very good agreement. This breathing technique tuning volumetric intensity modulated radiation therapy using a rotary moving along the thoracic or abdominal breathing can be applied to the treatment of tumors is considered. The actual treatment of patients through the goggles of the respiratory cycle to create Amplitude mode Gated RapidArc treatment equipment that does not automatically apply to the results about 5-6 seconds stopped breathing in breathing synchronized rotary volumetric intensity modulated radiation therapy facilitate could see complement.

Effects of Histone Deacetylase Inhibitor, Trichostatin A, on the Differentiation of C2C12 Myoblasts and the Expression of Cell Cycle Regulators (히스톤 탈아세틸화 효소 억제제 trichostatin A가 C2C12 myoblast 세포 분화와 세포주기 조절인자의 발현에 미치는 영향)

  • Lee, Won-Jun
    • Journal of Life Science
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    • v.17 no.7 s.87
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    • pp.976-982
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    • 2007
  • The purpose of this study was to determine the modulating effects of histone deacetylase inhibitor, trichostatin A, on the differentiation of mouse C2C12 myoblasts. We demonstrated that trichostatin A induced morphological changes of C2C12 myoblasts into smooth muscles and significantly increased the gene expression of smooth muscle markers including smooth muscle ${\alpha}-actin$ and transgelin. These results were due to the change in the expression level of cell cycle regulators in trichostatin A-treated C2C12 cells. Real-time PCR data revealed that cyclin dependent kinase inhibitor, p21, mRNA expression was significantly increased in trichostatin A-treated C2C12 cells. However, trichostaDn A rapidly decreased cyclin Dl mRNA expression necessary for cell cycle progression in 24hr after treatment. In conclusion, the strong inhibitory effects of trichostatin A on histone deacetylation induced transdifferentiation of C2C12 myoblasts into smooth muscle cells and these results are partly due to the changes in the expression of cell cycle regulators such as p21 and cyclin D1.