• Title/Summary/Keyword: 주기적 상관성

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Neutropenia & Nutritional status during Chemotherapeutic cycle in Acute Myeloid Leukemia (급성골수성백혈병환자의 항암화학요법 주기내의 호중구감소증과 영양상태)

  • Kim, Myung-Hee;Kang, In-Soon;Jo, Ho-Yoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.10 no.2
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    • pp.438-446
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    • 2009
  • This study aims to investigate chemotherapy-induced neutropenia, nutritional status and both relation of patients with acute myeloid leukemia during 1st consolidation chemotherapy and the therapy-related cytopenic phase in order to determine more effective nutritional support. We review medical records of total 54 cases received first consolidation chemotherapy on P hospital in Busan. The duration of neutropenia(Absolute Neutrophil Count<$1000/{\mu}{\ell}$) is mean 14.78 days, neutropenia occur on mean 10th(9.54) day of chemotherapy(D10). The nutritional parameters of total protein, body weight, BMI showed no significant interval change during chemotherapeutic cycle except albumin, cholesterol. The neutropenia wasn't dependent on general factor of gender, age, comorbidities, Body Surface Area(BSA). The correlation wasn't revealed between neutropenia and nutritional status. In conclusion, although nutritional status didn't affect neutropenia, this study provides detailed information on the neutropenic response of acute myeloid leukemia patients during induction chemotherapy.

Efficient Successive Transmission Technique in Event Based OS for Sensor Network (센서네트워크를 위한 이벤트 기반 운영체제에서 효율적인 연속적 전송 기법)

  • Lee, Joa-Hyoung;Lim, Hwa-Jung;Seon, Ju-Ho;Jung, In-Bum
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.12 no.1
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    • pp.205-214
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    • 2008
  • To transfer large amount of packets fast in sensor network, it is necessary that the delay between successive packet transmissions should be minimized as possible. In Sensor network, since the Operating Systems are worked on the event driven, the Timer Event is used to transfer packets successively. However, since the transferring time of packet completely is varies very much, it is very hard to set appropriate interval. If interval is too long, delay also becomes too long but if interval is too short, the fail of transfer request would increase. In this paper, we propose ESTEO which reduces the delay between successive packet transmissions by using SendDone Event which informs that a packet transmission has been completed. In ESTEO, the delay between successive packet transmissions is shortened very much since the transmission of next Packet starts at the time when the transmission of previous packet has completed, irrespective of the transmission time. Therefore ESTEO could provide high packet transmission rate given large amount of packets.

Fear of Falling and Related Factors in Elderly Living Alone Based on Fall Experience (독거여성노인의 낙상경험에 따른 낙상두려움과 관련요인)

  • Lee, Myungsuk;Lee, Yunbok
    • Journal of agricultural medicine and community health
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    • v.38 no.4
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    • pp.243-256
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    • 2013
  • Objectives: This study was to investigate fear of falling and related factors in elderly living alone based on fall experience. Methods: Participants were 404 elderly women(faller=148, non-faller=256) over 65 years who were homebound living alone in Jeollanam-do Province. Face-to-face interviews were conducted using questionnaires from April $23^{th}$ to June $9^{th}$ 2013. The questionnaires consisted of demographic variables, fall experience, Fear of falling questionnaire(FOFQ), Falls Efficacy Scale(FES) and Center for Epidemiologic Studies Depression(CES-D). The collected data were analyzed using the SPSS version 14.0. Results: The fear of falling and the influential factors were different according to fall experience. Regression model for fear of falling in fallers significantly accounted for 46.1%(F=6.71, p<0.001); difficulty of performing activity, depression, fall-efficacy, static balance and assistive devices. Regression model for fear of falling in non-fallers significantly accounted for 55.2%(F=15.16, p<0.001); fall-efficacy, environmental hazards, difficulty of performing activity, risk of nutrition, housing type, dizziness and assistive devices. Conclusion: Results demonstrate that fall is an important health problem for elderly women living alone, and show fall experience for factors influencing fear of falling. These results could be used in the developing fall prevention programs.

Reactor Neutron Noise Analysis using AR Spectral Estimation (AR 스펙트럼 추정법을 이용한 원자로 중성자 잡음 신호 해석)

  • Sim, Cheul-Muu;Hwang, Tae-Jin;Baik, Heung-Ki
    • The Journal of the Acoustical Society of Korea
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    • v.16 no.5
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    • pp.83-91
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    • 1997
  • A reactor vibration monitoring has been performed using neutron noise obtained from excore detectors for the safety operation, Traditionally, the spectral estimator based on Fourier analysis has been widely used in the noise analysis of the reactor system. If the bias is too severe, the resolution would not be adequate for a given application. One major motivation for the current interests in the parametric approach to spectral estimation is the apparent higher resolution achievable with these modern techniques. In considering an unbias, a consistency, an efficency, and a minimum lower bound of the statictic estimation, an AR model is appropriate for noise spectral estimation with sharp peaks but not deep valley. In order to select an appropriate model order, the lag value of autocorrleaton function is applied. Burg method to trace the vibration mode of RPV internal is the most sucuessful.

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Internal Tidal Oscillations of Temperature off Jukbyun on the East Coast of Korea (동해 죽변 연안해역에서 조석주기의 내부수온변동)

  • 이홍재;신창웅
    • 한국해양학회지
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    • v.27 no.3
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    • pp.228-236
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    • 1992
  • Internal temperature oscillations of tidal periods were studied using data observed by a thermistor chain in summer of 1980 off Jukbyun on the mid-east coast of korea. The vertical stratification was well established during the observation period. The spectral energy was found to be predominant in the semidiurnal tidal band and its energy increased with depth with maximum near the bottom. The coherence in the semidiurnal band between different depths is high with a small phase difference. The results suggest the existence of the internal tide of semidiurnal period. The amplitude of internal tide was of the order of 10 m and the largest just before the disappearance of the internal tide signal.

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Benzo[a]pyrene-induced Modification on p53 and Related Proteins (벤조피렌에 의한 p53 및 관련 단백질 변화)

  • Lee Sun-Mi;Ye Sang-Kyu;Choi Jinhee
    • Environmental Analysis Health and Toxicology
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    • v.20 no.1
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    • pp.23-28
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    • 2005
  • PAH 위해성 평가의 생체지표 개발을 위하여, benzo[a]pyrene을 인체 간암 세포주인 HepG2세포에 처리하여 암 억제 단백질인 p53 및 관련 단백질의 발현 양상에 대하여 연구하였다. HepG2 세포의 생존력은 benzo[a]pyrene을 노출시킨 군에서 농도가 증가할수록 감소하였다. p53과 인산화 p53의 발현 양상은 benzo[a]pyrene 농도 의존적으로 증가하는 경향을 보였으며, 반면에 아세틸화 p53은 benzo[a]pyrene의 농도가 증가할수록 감소하는 경향을 나타내었다. 세포 주기 조절에 관련된 p21 단백질은 화학 물질 처리에 의해서 p53과 마찬가지로 증가하였으나, CdK4와 Rb 단백질의 발현에는 변화가 없었다. 상관분석 결과 Benzo[a]pyrene 노출, 세포 생존력, p53, 인산화 p53, p21이 서로 높은 상관성을 보였다. 본 연구의 결과는 p53 단백질의 축적이 benzo[a]pyrene 독성에 있어 매우 중요한 현상이며, 이는 선택적인 지표와 함께 p53 이 benzo[a]pyrene과 같은 PAH 계열의 물질의 위해성 평가를 위한 민감한 생체 지표로써 개발될 수 있음을 시사한다.

Statistical Characteristics of Groundwater Level Time Series at Groundwater Monitoring Wells in Korea (국내 지하수 관측소의 지하수위 시계열자료의 통계적 특성)

  • Hwang, Chan-Ik;Hwang, Tae-Wong;Kim, Gyoo-Bum
    • Proceedings of the Korea Water Resources Association Conference
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    • 2020.06a
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    • pp.287-287
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    • 2020
  • 2016년말 우리나라의 지하수 관측망은 국가지하수관측망, 지역지하수관측망, 수질전용측정망, 해수침투 관측망 등 다양한 목적하에 약 5,790개가 운영되고 있으며, 평균적으로 약 10년 정도의 관측 기간을 보유하고 있다. 이들 중에서 일 1회 이상 자동관측이 이루어지는 679개를 대상으로 지하수위 시계열자료의 특성을 분석하였다. ARIMA 분석 결과, AR(p) 모델은 전체의 56.8%인 386개, MA(q) 모델은 90.7%인 616개, Integration(d) 모델은 96.5%인 655개로 나타났다. AR(p) 모델중 가장 많은 경우를 보인 것은 AR(1), AR(2), AR(3) 등의 순이며, MA(q) 모델중 가장 많은 경우를 보인 것은 MA(2), MA(1), MA(3) 등의 순이며, Integration(d) 모델은 I(1), I(2)의 순으로 나타났다. AR(1) 모델이 가장 많은 것은 강우에 대한 지하수위의 교차상관의 lag time이 1 ~ 2일인 경우가 가장 많으므로 이전 시점의 지하수위에 의하여 현재 지하수위가 결정된다는 점을 의미한다. Integration이 많이 나타난 이유는 주기적 또는 지속적인 변동성이 지하수위에 나타나고 있음을 보여준다. 지하수위의 시계열 특성의 분류 및 그 원인을 평가하여 각 관측소별 지하수위 변동성을 정의함으로써 추후 지하수위 시계열자료의 분석 목적에 부합하는 자료 선별에 기여하고자 한다.

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Assessment of Site Environmental Factors on the Structure of Forest Vegetation in Naejang-san National Park Using Canonical Correlation Analysis (정준상관분석을 통한 내장산국립공원 산림식생구조의 입지환경 평가)

  • Kim, Tae-Geun;Cho, Young-Hwan;Oh, Jang-Geun
    • Korean Journal of Ecology and Environment
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    • v.46 no.4
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    • pp.561-569
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    • 2013
  • This study examines locational environment factors that may affect the vegetation structure in the forests of Naejang National Park. To that end, we selected LAI (Leaf Area Index), diameter at breast height, and tree height as structural variables as well as altitude above sea level, gradient, slope direction, soil moisture, topographic location, and amount of solar radiation as locational environment factors, using the method of canonical correlation analysis in order to find out correlation between them. As to the simple correlation between the locational environment factors and structural variables, the correlation coefficient was relatively low (0.6). The values of LAI, measured along the ridge with higher altitudes, decreased as the soil moisture and solar radiation increased. However, LAI increased as the gradient increased and the slope direction faced the north (farther from the east). In respect of the diameter at breast height, the diameter decreased as the altitude and gradient increased. But the diameter increased as the moisture and solar radiation increased. The tree height decreased as the moisture increased and the site was closer to the ridge. These various correlations show a variety of locational environment factors in the national park, implying that the structural variables are affected by complex locational environment factors. This study conducted a canonical correlation analysis on locational environment factors which may affect the vegetation structure, and the result showed that LAI increased and tree height & diameter at breast height decreased as the solar radiation & moisture decreased and altitude increased. Although more factors that may affect vegetation structure (e.g. climate) should be taken into account, this study is significant in that the vegetation structure, which can adapt to more unfavorable conditions in terms of solar radiation, moisture, and higher altitudes, could be inferred in a statistical way. The results of this study, especially the locational environment factors based on DEM, can be used for assessing diversity of vegetation structure in a forest and for monitoring the structure in a national park on a regular basis so as to establish more effective maintenance plans of a park.

Prediction of replacement period of shield TBM disc cutter using SVM (SVM 기법을 이용한 쉴드 TBM 디스크 커터 교환 주기 예측)

  • La, You-Sung;Kim, Myung-In;Kim, Bumjoo
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.21 no.5
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    • pp.641-656
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    • 2019
  • In this study, a machine learning method was proposed to use in predicting optimal replacement period of shield TBM (Tunnel Boring Machine) disc cutter. To do this, a large dataset of ground condition, disc cutter replacement records and TBM excavation-related data, collected from a shield TBM tunnel site in Korea, was built and they were used to construct a disc cutter replacement period prediction model using a machine learning algorithm, SVM (Support Vector Machine) and to assess the performance of the model. The results showed that the performance of RBF (Radial Basis Function) SVM is the best among a total of three SVM classification functions (80% accuracy and 10% error rate on average). When compared between ground types, the more disc cutter replacement data existed, the better prediction results were obtained. From this results, it is expected that machine learning methods become very popularly used in practice in near future as more data is accumulated and the machine learning models continue to be fine-tuned.

Prediction of Pregnancy Outcomes by Uterine Artery Impedances on the Day of Embryo Transfer in Human IVF (인간 체외수정술에서 배아 이식일의 자궁동맥 임피던스에 따른 임신의 예측)

  • Jeong, Ju-Eun;Jo, Moo-Sung;Kim, Seung-Chul;Joo, Jong-Kil;Choi, Jong-Ryeol;Lee, Kyu-Sup
    • Clinical and Experimental Reproductive Medicine
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    • v.36 no.4
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    • pp.293-300
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    • 2009
  • Objective: This study was aimed to investigate whether uterine blood flow on the day of embryo transfer can be a predictor of pregnancy outcome in human IVF. Methods: Fifty-one patients undergoing IVF program were included in this study. Serum estradiol levels were measured on the day of hCG administration and uterine pulsatility index (PI) and resistance index (RI) was examined for at embryo transfer of day 3. Results: Of 51 cycles, 22 cycles were clinically pregnant (43.1%) and the implantation rate was 14.7%. Uterine PI and RI had a significant inverse correlation with serum estradiol levels (p<0.05). These uterine blood flows were not significantly different between pregnant and nonpregnant groups. The pregnancy rate was slightly higher in patients with PI more than 3.0 compared to those with PI of 3.0 or less, but there was no significant difference. Conclusion: These results suggest that uterine PI and RI at the day of embryo transfer could not be a good predictor of pregnancy in IVF treatment. But they had an inverse correlation with serum estradiol levels on the day of hCG administration.