• Title/Summary/Keyword: 조직등가물질

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Analysis of Tissue Equivalent Characteristics of Agar Phantom for Hyperthermia Therapy (온열종양치료 한천 팬텀의 조직등가 특성 분석)

  • Jeong-Geun Park;Kyeong-Hwan Jeong;Jeong-Min Seo
    • Journal of the Korean Society of Radiology
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    • v.17 no.6
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    • pp.985-991
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    • 2023
  • A tissue-equivalent phantom is necessary for quality control of hyperthermia therapy. However, since there is no phantom for this purpose, phantoms made from agar are being used in various studies. The tissue-equivalent properties of the agar phantom were confirmed by comparison with the tissue-equivalent material bolus in this study. CT images of the agar phantom and bolus were acquired, and tissue equivalent characteristics were analyzed with image analysis and dose calculation using a computerized radiation therapy planning system. The average pixel value was 96.960±10.999 in bolus, 108.559±8.233 in 3% agar phantom, and 111.844±8.651 in 4% agar phantom. Using the SSD technique, 100 cGy was prescribed at a depth of 1.5 cm and 6 MV X -ray was set to irradiated to 10x10 cm2, and the absorbed dose according to depth was calculated from the central axis of the beam. The intraclass correlation coefficient of dose distribution of bolus, 3% agar phantom, and 4% agar phantom was 0.979 (p<.001, 95%CI .957-.991). The density (g/cm3) at the point where the absorbed dose was calculated was 0.990±0.020 at the bolus, 1.018±0.020 at the 3% agar phantom, and 1.035±0.024 at the 4% agar phantom. In this study, the internal density distribution and uniformity of the agar phantom were confirmed to be appropriate as a tissue equivalent material by analysis of CT images and a computerized radiation therapy planning system.

A Study on the Efficiency Evaluation of Ultrasound Therapy Using Varicose Vein Simulated Tissue Phantom and Tissue Equivalent Phantom (하지정맥류 모사 생체조직 팬텀과 조직등가 팬텀을 이용한 초음파 치료효과 평가에 관한 연구)

  • Kim, Ju-Young;Jung, Tae-Woong;Shin, Kyoung-Won;Noh, Si-Cheol;Choi, Heung-Ho
    • Journal of the Korean Society of Radiology
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    • v.12 no.3
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    • pp.427-433
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    • 2018
  • Because of the expectation of the non-invasive treatment effect, Various studies on the treatment of varicose veins using focused ultrasound are reported. In this study, the bio-tissue phantom and tissue equivalent phantom that can be applied to estimation of ultrasonic varicose veins treatment effect. Each phantom was evaluated for its usefulness by evaluating the acoustic characteristics and the shrinkage rate according to the ultrasonic irradiation. A multi-layer structure phantom with three layers of skin, fat, and muscle was constructed considering the structure of the tissue where the varicose veins occurred. The materials constituting each layer were made to have characteristics similar to human body. In addition, the multi-layered phantoms with blood vessel mimic tube, with bovine blood vessel, and with animal tissue were fabricated. The degree of shrinkage of blood vessel mimic material and vascular tissue according to ultrasonic irradiation was evaluated using B-mode image. As the results of this study, it was thought that the proposed phantom could be used effectively in the evaluation of ultrasonic varicose veins treatment. In addition, it is thought that these phantoms could be applied to the development of varicose vein treatment device using the focused ultrasound and the verification of the therapeutic effect.

Dose Calculation of Heterogeneous Lung Tissue on 6MV X-ray Therapy (6MV X-선에 의한 폐조직의 심부선량변화와 임상응용)

  • 이경자;장승희;추성실
    • Progress in Medical Physics
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    • v.9 no.4
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    • pp.247-257
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    • 1998
  • For effective radiotherapy, it should always be considered that calculation of different dose distribution in heterogenous tissue is important particularly on lung which has low density and large volume. To take precise dose distribution of 6MV X-ray in the thoracic cage, the authors had made a tissue equivalent phantom for thorax, measured dose distribution by thermoluminescent dosimeter and mm dosimeter, and derived methmetical equation coincided with provided theoretical formula. In comparision with isodose curve on case of homogeneous soft tissue, dose of heterogeneous lung tissue had been shown increase about 4% per cm depth on one and multiportal field, less than 15% difference on rotation field for esophagus, and around 20% difference on rotation field for lung according to the degree of rotation angle that must be corrected by dose compensation.

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A Study of Radiation Dose Reduction using Bolus in Medical Radiation Exam (볼루스를 이용한 방사선영상검사 피폭선량저감 연구)

  • Jeong-Min Seo
    • Journal of the Korean Society of Radiology
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    • v.17 no.6
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    • pp.1001-1007
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    • 2023
  • Dose limits are not applied to medical radiation exposure therefore justification and optimization should be essential for protecting radiation. This study explores methods to reduce exposure dose undergoing general radiation exam by bolus(tissue equivalent material) with keeping image quality. Hand PA projection with 50 kVp, 5 mAs, SID 100 cm, and 8×10 inch is referred by covered bolus of thickness 0, 3, 5, 8, and 10 mm for evaluation entrance dose and SNR. The entrance dose (μGy) to the hand by bolus thickness was 125.41±0.288, 106.85±0.255, 104.97±0.221, 91.68±0.299, and 90.94±0.106 showing a significant reduction in radiation exposure depending on if the bolus was used and bolus thickness. The SNR of the image was 13.997, 13.906, 12.240, 12.538, and 12.548 at each bolus thickness, showing no significant difference. It was confirmed that if appropriate thickness and size of bolus is used depending on the type of radiological imaging exam and the body site, a significant radiation dose reduction effect can be achieved without deteriorating image quality.

Skin Dose Distribution with Spoiler of 6 MV X-ray for Head and Neck Tumor (두경부암 치료를 위한 6 MV X-선 산란판의 제작과 산란분포 측정)

  • Lee Kyung-Ja;Chu Sung Sil
    • Radiation Oncology Journal
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    • v.14 no.4
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    • pp.339-345
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    • 1996
  • Purpose : This study was performed for adequate irradiating tumor area when 6 MV linear accerelator photon was used to treat the head and neck tumor. The skin surface dose and maximum build-up region was measured by using a spoiler which was located between skin surface and collimator. Methods : A spoiler was made of tissue equivalent material and the skin surface dose and maximum build-up region was measured varing with field size, thickness of spoiler and interval between skin and collimator. The results of skin surface dose and maximum build-up dose was represented as a build-up ratio and it was compared with dose distribution by using a bolus. Results : The skin surface dose was increased with appling spoiler and decreased by distance of the skin-spoiler separation. The maxium build-up region was 1.5 cm below the skin surface and it was markedly decreased near the skin surface. By using a 1.0-cm thickness spoiler, Dmax moved to 5, 10.2, 12.3 13.9 and 14.8 mm from the skin surface by separation of the spoiler from the skin 0, 5, 10, 15. 20 cm, respectively. Conclusion : The skin surface dose was increased and maximum build-up region was moved to the surface by using a spoiler. Therefore spoiler was useful in treating by high energy photon in the head and neck tumor.

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Comparative Analysis of Bone Mineral Contents with Dual-Energy Quantitative Computed Tomography (이중에너지광자선의 전산화단층촬영술을 이용한 정량적 골무기물함량의 비교분석)

  • Choi, Tae-Jin;Yoon, Seon-Min;Kim, Ok-Bae;Lee, Sung-Moon;Suh, Soo-Jhi
    • Radiation Oncology Journal
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    • v.15 no.2
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    • pp.153-158
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    • 1997
  • Purpose : The Dual-Energy Quantitative Computed Tomography(DEQCT) was compared with bone equivalent $K_2HPO_4$ standard solution and ash weight of animal cadaveric trabecular bone in the measurement of bone mineral contents(BMC). Method and Materials : The attenuation coefficient of tissues highly depends on the radiation energy density and effective atomic number of composition, The bone mineral content of DEQCT in this experiments was determined from empirical constants and mass attenuation coefficients of bone,fat and soft tissue equivalent solution in two photon spectra. In this experiments, the BMC of DEQCT with 80 and $120kV_p$ X rays was compared to ash weight of animal trabecular bone. Results : We obtained the mass attenuation coefficient of 0.2409 0.5608 and 0.2206 in $80kV_p$, and 0.2046, 0.3273 and $0.1971cm^2/g$ in $120kV_p$ X-ray spectra for water bone and fat equivalent materials, respectively. The BMC with DEQCT was acomplished with empirical constants $K_1=0.3232,\;K_2$=0.2450 and mass attenuation coefficients has very closed to ash weight of animal trabecular bone The BMC of empirical DEQCT and that of manufacturing DEQCT were correlated with ash weight as a correlation r= 0.998 and r= 0.996, respectively. Conclusion : The BMC of empirical DEQCT using the experimental mass attenuation coefficients and that of manufacture have showed very close to ash weight of animal trabecular bone.

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