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Study on the Amendment of Standard Regulations of Food Additives and Contaminants for Infant Formulas in Korea (우리나라 영.유아용 조제식의 식품첨가물과 오염물질 기준 개선방안 연구)

  • Moon, Ji-Hea;Lee, Heon-Ok;Shim, Jae-Young;Kim, In-Hye;Shin, Hye-Seoung;Won, Sun-Im;Paik, Min-Kyoung;Shin, Hyoung-Soo;Om, Ae-Son
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.37 no.9
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    • pp.1214-1221
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    • 2008
  • The aim of this study is to propose suggestions for establishing Korean regulatory standards of infant formula. Accordingly, the regulatory standards for food contaminants and additives in Korean infant formulas were compared and analyzed with those in CODEX, EU, Australia and New Zealand. Several suggestions for regulations were found from different countries. Firstly, it is advisable that additives for nutrient supplement of infant formula be classified as types of nutrients. Secondly, it is proposed that guidelines should be set on the maximum amount of additives in infant formula. Thirdly, pathogens such as Staphylococci and Salmonella of infant formula should be regulated. Finally, present regulations need to establish the maximum permissible levels of some pesticides, Pb and Al, that other countries are already regulating. These proposed recommendations would broaden the scope of infant formula regulatory standards needed for infants' health.

Use-friendly Active Packaging of Powdered Infant Formula in Single-serve Portion Augmented with Anti-oxidative Function (산화억제 가능성과 사용편의성을 가진 일회성 조제분유 포장)

  • Lee, Hye Lim;An, Duck Soon;Lee, Dong Sun
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.25 no.3
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    • pp.95-99
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    • 2019
  • In the modified atmosphere packaging of powdered infant formula, the oxygen inside the package may cause its quality deterioration and needs to be minimized for quality preservation. A way of oxygen scavenger inclusion in the single-serve package without contacting the product was devised for removing oxygen residing initially and permeating through the seal layer during the storage. A polyethylene/pulp multi-layer porous filter bag of 5 × 7 cm containing 13 g of powdered infant formula was packaged in an 8 × 9 cm size aluminium laminated film package with a Fe-based oxygen scavenger of 1.8 g. After nitrogen flushed packaging, the active packages were stored at 30℃ for 254 days with periodical quality measurement. The active package could remove the initial residual oxygen of 1.4% completely and maintain absence of oxygen for the whole storage, which contributed to reduced oxidation observed in lower product peroxide value compared to that of the product in the control package. There was no influence of packaging treatment on content of 5-hydroxymethylfurfural, reaction product of initial nonenzymatic browning. The devised oxygen-scavenging single-serve package showed a potential to improve the preservation of infant formula powder and extend the shelf life.

Hand Exposure of Operator to Chlorpyrifos during Mixing/loading and Risk Assessment (유기인계 살충제 Chlorpyrifos 유제 살포액 조제 시 농작업자의 손 노출량 측정 및 위해성 평가)

  • Kim, Eunhye;Lee, Hyeri;Jeong, Mihye;Hong, Soonsung;Kim, Jeong-Han
    • The Korean Journal of Pesticide Science
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    • v.16 no.4
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    • pp.391-394
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    • 2012
  • Exposure and risk assessment during mixing/loading of chlorpyrifos emulsifiable concentrate (EC, 20%) were carried out. Limit of detection and limit of quantitation were 0.02 and 0.1 ng, respectively. Calibration curve linearity and reproducibility were excellent. Recovery of chlorpyrifos from gloves was 72.3-103.4%. During mixing/loading procedure, average hand exposure amount of chlorpyrifos was 3.9 mg which is corresponding to 0.004% of total active ingredient in the prepared spray mixture. In calculation of MOS (Margin of Safety) for risk assessment, male Korean average body weight and AOEL (Acceptable Operator Exposure Level) were used. Nine events of mixing/loading procedure were assumed per day. And 75 percentile of 30 repetition (4.6 mg) was used as for the worst case. MOS was more than 1 for total repetition, indicating mixing/loading work was of least risk. However, MOS of individual repetition was examined, two cases were less than 1 suggesting careful work habit is essential in mixing/loading procedure.

Investigation of the Transfer Rate of Zearalenone in Herbal Medicines to Their Decoction (한약재 중 제랄레논의 탕액으로 이행률 조사)

  • Shim, Won-Bo;Song, Jeong-Eon;Kim, Jeong-Sook;Chung, Young-Chul;Chung, Duck-Hwa
    • Korean Journal of Food Science and Technology
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    • v.45 no.3
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    • pp.312-316
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    • 2013
  • The objective of this study was to establish an analytical method to detect zearalenone (ZEA) in herbal medicines and their decoctions and investigate the ZEA transfer rate from raw materials of herbal medicines to their decoctions. Herbal medicines (Trichosanthis Semenm, Eucommiae Cortex, Rubi Fructus) spiked with a known concentration of ZEA were presoaked or unsoaked (as a pretreatment) and boiled for 3 h at $100^{\circ}C$ or autoclaved for 1 h at $121^{\circ}C$. The decoction and the remnants were separated, cleaned up with an immunoaffinity column, and analyzed using HPLC. Recoveries for decoctions and remnants were 68.39-83.68% and 72.91-80.25%, respectively. ZEA was not detected in the decoction, whereas it was found in the remnants. Although ZEA in the raw material of herbal medicines was not transferred into the decoction during heating and autoclaving, the continuous monitoring for ZEA in raw herbal medicines should be carried out for the safe ingestion and utilization of herbal medicines.

Effects of Activator on Rubber Characteristics for Gasket to Lithium Ion Battery (리튬 이온 전지용 개스킷 고무 물성에 미치는 가교조제의 영향)

  • Kang, Dong-gug;Kim, Hye-young;Kang, Young-im;Hur, Byung-ki;Seo, Kwan-ho
    • Applied Chemistry for Engineering
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    • v.22 no.4
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    • pp.395-399
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    • 2011
  • Material of the gasket for lithium ion battery requires the chemical resistance, the electrical insulting property, the compression set, the anti-contamination level and the low temperature resistance. We compounded ethylene propylene diene monomer (EPDM), which showed widely different solubility parameter index, with adjusting the amount of metal oxide as an activator. We did long-term test and compression set against an electrolyte with consideration for operating conditions in lithium-ion battery. In these tests, we checked the physical, chemical characteristics and the effect to lithium ion battery with different kinds of activators. In case of rubber with ZnO as an activator, through 1000 h depositing test in propylene carbonate which is one of representative solvents, we could get the satisfying characteristics and result. However, $Zn^{2+}$ had eluted in the ion elution test. So, ZnO should be limited in EPDM compound for the gasket material in lithium-ion battery.

Improvement of Analysis Methods for Fatty Acids in Infant Formula by Gas Chromatography Flame-Ionization Detector (GC-FID를 이용한 조제유류 중 지방산 분석법 개선 연구)

  • Hwang, Keum Hee;Choi, Won Hee;Hu, Soo Jung;Lee, Hye young;Hwang, Kyung Mi
    • Journal of Food Hygiene and Safety
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    • v.36 no.1
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    • pp.34-41
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    • 2021
  • The purpose of this research is to improve analysis methods of determining the contents of fatty acids in infant formulas and follow-up formulas. A gas chromatography (GC) method was performed on a GC system coupled to flame ionization detector, with a fused silica capillary column (SP2560, 100 m×0.25 mm, 0.20 ㎛). The method was validated using standard reference material (SRM, NIST 1849a). Performance parameters for method validation such as specificity, linearity, limits of detection (LOD) and quantification (LOQ), accuracy and precision were examined. The linearity of standard solution with correlation coefficient was higher than 0.999 in the range of 0.1-5 mg/mL. The LOD and LOQ were 0.01-0.06 mg/mL and 0.03-0.2 mg/mL, respectively. The recovery using standard reference material was confirmed and the precision was found to be between 0.8% and 2.9% relative standard deviation (RSD). Optimized methods were applied in sample analysis to verify the reliability. All the tested products had acceptable contents of fatty acids compared with component specification for nutrition labeling. The result of this research will provide efficient experimental information and strengthen the management of nutrients in infant formula and follow-up formula.

Nonlinear Goal Programming for Optimizing Rice Conditioning and Storage Systems : Part I…Modeling (벼 조제(調製) 및 저장(貯藏)시스템의 최적화(最適化)를 위한 비선형(非線型) 골 프로그래밍(I))

  • Chang, D.I.;Chung, D.S.;Hwang, C.L.
    • Journal of Biosystems Engineering
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    • v.8 no.2
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    • pp.69-85
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    • 1983
  • Nonlinear Goal Programming(NGP)이 Multiple Objective Decision Making(MODM) 문제(問題)를 적정화(適正化)할 수 있는 방법(方法)으로 소개(紹介)가 되었다. 그리고 6 가지의 벼 조제(調製) 및 저장시설(貯藏施設)을 분석(分析)한 후, NGP에 의(依)하여 적정시설설계(適正施設設計)를 하기 위하여 Model Systems를 개발(開發)하고 그에 의(依)하여 MODM의 수학적(數學的) 모형(模型)을 개발(開發)하였다.

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The assessment of fat absorption rate and Ca bioavailability in rats fed high sn-2 palmitate formula diet (sn-2 팔미틴산 강화유지를 섭취한 흰쥐의 지방흡수율 및 칼슘 체내이용성 측정)

  • 강은영;이연숙
    • Proceedings of the KSCN Conference
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    • 2003.05a
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    • pp.136-136
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    • 2003
  • 중성지방(TG)은 모유와 조제분유의 주요에너지원이며 전체에너지의 50%까지 제공한다. 그러나, 일반 조제분유와 모유의 TG구조는 상당히 다르며, 이러한 구조적 차이로 인해 지방 및 칼슘흡수에 차이가 생긴다. 즉, 모유지방산의 1/4정도를 구성하는 팔미틴산은 이것의 70%정도가 glycerol 의 두 번째 탄소에 결합되어 있는 sn-2(middle)position으로 되어 있으며, 이러한 위치의 팔미틴산은 일반적으로 췌장지방분해 효소에 의해 분해되지 않고 2-monoglyceride로 존재한다. (중략)

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Developing an RFID Application Solution for Detecting Human Errors in Filling Prescriptions (처방약 조제 오류방지를 위한 RFID 응용솔루션 개발)

  • Hong, Min-Sun;Rim, Suk-Chul
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 2005.05a
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    • pp.100-105
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    • 2005
  • 최근들어 RFID기술은 향후 바코드를 대체할 자동인식기술로 주목받고 있으며, 특히 유통물류분야의 응용이 기대되고 있다. 그러나 비용을 고려할 때 RF tag를 단품마다 적용하기에는 앞으로도 상당한 기간이 필요할 것으로 보인다. 오히려 인간의 생명과 안전을 다루는 의료분야에서 RFID를 사용하여 인간의 실수를 방지하는 응용시스템은 비용이 정당화되는 유용한 적용사례가 될 수 있다. 본 연구에서는 병원이나 약국의 처방약 조제과정에서의 인간의 오류를 방지할수 있는 RFID 응용시스템을 소개하고, 그 구조 및 개발사례를 소개한다.

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Eye Irritation Test of New Contact Lens Cleaner

  • Oh, Se-Woong;Ha, Jong-Ryul;Hong, Seong-Jin;Park, Kun-Hyock
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1996.04a
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    • pp.274-274
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    • 1996
  • 1차적인 제형의 조제를 위해서 비이온성 계면활성제인 poloxamer 류, Tween 류, octylphenylether와 양심 계면활성제인betaine 류와 방부제인 croquat 류에 대한 시험을 실시하여 자극을 나타내지 않은 성분을 선별하였다. 이를 근거로 isotonic sodium borate 용액을 완충액으로 사용하여, 최종제형을 조제하여 시험한 결과 자극반응을 나타내지 알았으며, 본 제형을 실온과 4$0^{\circ}C$에서 2, 4, 6개월간 안정성 시험을 거친 후 시험시에도 전혀 자극반응을 나타내지 않았다.

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