• Clinical and Experimental Pediatrics
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• v.50 no.10
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• pp.959-964
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• 2007

Purpose : The purpose was to investigate the clinical considerations of patients affected by meconium aspiration syndrome (MAS) and the effect of suctioning through endotracheal intubation immediately after delivery on the prognosis of MAS. Methods : A total of 44 inpatients diagnosed as MAS in the Neonatal Intensive Care Unit (NICU) at Cheil Hospital were selected from January 2004 to June 2006. They were divided into two groups. In the early aspiration group (12 patients), suctioning through endotracheal intubation was performed according to the neonatal resuscitation program of the American Academy of Pediatrics and the American Heart Association because infants born through meconium-stained amniotic fluid (MSAF) were not vigorous after birth. In the early non-aspiration group (32 patients), endotracheal intubation was not performed because the infants born through MSAF were vigorous after birth. These two groups were analyzed retrospectively by medical records in the fields of clinical features, obstetric risk factors, complications, treatment, and duration of hospitalization. Results : There was no significant difference in mean gestational age, mean birth weight, sex, and delivery mode between the early aspiration group and the early non-aspiration group. Mean Apgar score of the early aspiration group both in 1 and 5 minute score was significantly lower than in the early non-aspiration group. Lengths of hospitalization and duration of mechanical ventilator care were longer in the early non-aspiration group, but there was no significant difference. Total duration of oxygen therapy was significantly longer in the early non-aspiration group than in the early aspiration group. Conclusion : In this study, the early non-aspiration group used surfactant more and had a longer duration of mechanical ventilator and hospitalization, but there was no significant difference. Total duration of oxygen therapy was significantly longer in the early non-aspiration group. Therefore, more detailed guidelines for vigorous infants born through MSAF are needed and we should study and follow up the long term prognosis of neurological complications of MAS.

• The korean journal of orthodontics
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• v.34 no.3 s.104
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• pp.205-218
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• 2004

The aims of this study were to investigate the differences in the early craniofacial morphology of Class III malocclusions with good, fair and poor occlusal stability and to elucidate a key determinant for distinguishing the cases. Lateral cephalograms of 30 subjects with Class III malocclusion in the mixed dentition were analyzed at the start of treatment (mean age of $8.58\pm1.47$). All subjects were reevaluated after a mean period of $7.50\pm1.94$ years comprising active treatment and retention. At this time, the samples were divided into three groups: good (10 subjects), fair (10 subjects) and poor (10 subjects) occlusal stability groups. According to the results of ANOVA, there were significant morphological differences in the early stage among the good, fair and poor occlusat stability groups, especially in variables that represented the vertical skeletal relationships. As well, there were already more dental compensations in the poor occlusal stability group. Stepwise discriminant analysis on the measurements at the time of first observation identified only one predictive variable: AB to mandibular plane angle(AB-MP). With this discriminant function, $83.3\%$of the original grouped cases were correctly classified and the canonical correlation coefficient was 0.857. In conclusion, AB-MP can be a possible predictor for the eventual prognosis of early Class III treatment. If it is below 60, the prognosis of early Class III treatment is expected to be poor, while if it is above 65, a good prognosis is expected.

• The Journal of the Korean dental association
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• v.25 no.6 s.217
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• pp.541-548
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• 1987

골수염은 조기에 적절한 치료를 하지않으면 중대한 후유증이 초래되므로 신속한 진단과 치료가 요구된다. 골수염을 진단하기 위해서는 구강검진, 방사선검사, 병리조직학적 검사, 혈액 및 세균배양검사와 골스캔등이 필요하다. 골수염의 감염과정은 골에 파괴적 및 재생적 변화의 양자를 모두 일으키지만 X선사진소견에서는 임상증상이 발현된 후 약 10내지 14일이 경과되어야만 골변화를 관찰할 수 있으며 그 이전에는 대체로 비특이적 연조직의 종창만을 보인단. 반면에 골스캔을 이용하면 급성염증기의 골질환을 감견하기가 용이하다. 골스캔제의 국소골섭취의 증가는 골의 어떤 부위에서 대사능이나 혈류가 증가된 경우에 일어나기 때문에, 실제로 임상증상이 발현된 후 24시간정도의 조기에 골스캔상은 양성반응을 보인다. 즉 골의 국소적 병변은 어느정도 신생골 형성과 골파괴가 같이 수반되어있고 이러한 신생골은 골스캔제와 친화력이 강하므로 골형성반응을 야기하는 어떠한 병변이라도 골스캔에 의하여 발견될 수 있다. 임상적으로 골수염에 대하여 골스캔을 시행하는 경우는 골수염의 조기진단, 골수염과 봉와직염과의 감별진단, 만성 공수염의 악화여부 및 치료에 대한 반응을 monitoring하기 위해서 시행된다.

• The Journal of the Korean dental association
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• v.43 no.5 s.432
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• pp.312-317
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• 2005

치아 우식증은 영유아기를 거쳐 학령기에 이르기까지 광범위하게 감염된 질환으로써 구강 위생 평가를 통한 적절한 대응과 조기 진단을 통한 조기 치료와 적절한 예방 프로그램을 통해 건강한 구강 건강관리를 도모할 수 있겠다. 우식 위험 평가에 대한 미국소아치과학회의 지침 내역을 정리해 보면 다음과 같다.

• Journal of the Korean Arthroscopy Society
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• v.13 no.2
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• pp.149-154
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• 2009

Purpose: We evaluated the level of pain and clinical presentation of calcific tendinitis after treatment with conservative and early arthroscopic operation. Materials and Methods: We reviewed 30 patients with calcific tendinitis with the minimum of 6 months of follow up period, treated from February 2002 to May 2008. We implemented Constant-Murley score to evaluate the pain of calcification and improvement of range of motion at the 2nd week, 12th week and 24th week with the patients who had treatment with steroid injection in 15 cases and operation in the other 15 cases. Results: Evaluating the level of pain using Constant-Murley score, we found that conservative treatment group had the scale of 3.2 before treatment and 13.6, 14.5 and 14.7 at 2nd, 12th, and 24th week, respectively since started treatment. The operation group, on the other hand, had the scale of 3.3 preoperatively and 10.2, 13.0, and 14.3 at 2nd, 12th and 24th week postoperatively. The range of motion in the conservative treatment group showed 14.3 on average before the treatment and 21.7, 31.3 and 35.7 at 2nd, 12th and 24th week after treatment. The operation group had 14.4 on average preoperatively, and 33.1, 35.8 and 36.4 at 2nd, 12th and 24th week postoperatively. The operation group had statistically significant improvement compared to the conservative group at the 2nd and 24th week, but showed no difference between the two groups at the final follow up. Conclusion: Early arthroscopic treatment of calcific tendinitis seems to be an excellent option that can increase the level of satisfaction of the patients and an efficient way of putting the patients back to their normal life promptly.

• RED RIBBON
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• s.39
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• pp.42-43
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• 2001

최근 많은 에이즈 치료전문가들은 에이즈바이러스를 단번에 퇴치할 수 없다는 사실을 인식하고 가능한 한 조기에 공격적인 방법으로 에이즈를 퇴치하겠다는 입장에서 환자들에게 강력한 복합 약물치료를 처방하지 않기로 하는 등 치료에 대한 태도를 신중한 자세로 바꾸고 있다.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.12 no.2
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• pp.99-103
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• 2012

Tyrosinemia type I is an autosomal recessive inborn error of tyrosine metabolism that caused a mutation. Clinical symptoms include progressive liver damage with liver failure, coagulopathy, hypophosphataemic rickets, renal tubular dysfunction and a high risk of hepatocellular carcinoma. If left untreated, the affected infants may die from liver failure within the first year of life. PharmacoloIcal therapy with 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC) has offered an effective therapeutic option in addition to dietary restriction of tyrosine and phenylalanine. As prognosis of tyrosinemia type I is improving with early diagnosis and early treatments, it meets the criteria for a condition that would benefit from newborn screening. We report a case of tyrosinemia type I diagnosed by newborn screening and successive biochemical analysis of plasma and urine, treated by dietary restriction and NTBC.

• 건강소식
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• v.10 no.5 s.90
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• pp.28-31
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• 1986

일반적으로 소아기 영양 상태는 그 사람의 성인 이후의 건강과 관계가 있는 것으로서 소홀히 다루어서는 안 된다. 최근 각종 인스턴트식품이 개발되면서 소아기의 식생활에 있어 불균형이 되고 있다. 이런 점은 가정과 학교가 협조하여 공동으로 소아의 식생활을 바로 잡아주어야 한다.

• Proceedings of the KTCVS Conference
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• 1998.10a
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• pp.50-50
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• 1998

• Journal of Gastric Cancer
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• v.8 no.4
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• pp.198-203
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• 2008

Purpose: Multiple early gastric cancer (MEGC) accounts for between 4.5% and 11.7% of all early gastric cancers (EGC). We investigated the treatment of MEGC from the viewpoint of the clinicopathologic features of the disease. Materials and Methods: 2,281 patients with EGC underwent gastric resection at the Department of Surgery, Severance Hospital during the 11 years between January 1994 and December 2004 and we carried out a retrospective analysis of these patients. Results: There were 91 cases of synchronous MEGC (4.0%) according to the diagnostic criteria of Moertel: there were 81 double, 9 triple and 1 quadruple lesions. Of the 102 accessory lesions, 64 (62.7%) were less than 10 mm in diameter and 83 (81.4%) were located in the same region as the main lesion. The most frequent histologic type of main lesion was a well differentiated adenocarcinoma, which was found in 52 cases (57.1%). There were 49 mucosal main lesions and 42 submucosal main lesions. Lymph node metastasis was detected in 6 cases (6.6%): 1 in mucosal lesions and 5 in submucosal main lesions Conclusion: Solitary EGC and MEGC had very similar clinopathological features and a similar prognosis. Therefore, we believe that the general EGC treatment guidelines can be applied for multiple EGC. It is important to evaluate the whole stomach before and during the operation and then after examining the resected specimen.