• Title/Summary/Keyword: 제거효율평가

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Development and Preliminary Evaluation of a Leukocyte Removal Aptamer Filter (압타머를 이용한 백혈구제거필터의 개발 및 예비평가)

  • Lee, Yangwon;Jung, Eun-Suk;Choi, Kyoung Young;Kim, Myung Han;Kwon, So Yong;Cho, Nam Sun;Kim, Jin Sook;Park, Han Jeong;Han, Byoung Don;Yoon, Soo-Young
    • The Korean Journal of Blood Transfusion
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    • v.23 no.2
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    • pp.107-114
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    • 2012
  • Background: Leukocyte reduction filters are widely used to prevent transfusion reactions caused by leukocytes in blood components. Commercial filters are not sufficient for removal of leukocytes for prevention of transfusion associated graft-versus-host disease; therefore, irradiation of blood components was performed using expensive equipment. Techniques using an aptamer substituted for antibody have been developed and are available in clinical areas. The purpose of this study is to develop the aptamer filter system and to evaluate its efficiency and the possibility of its clinical application. Methods: Aptamers targeted to CD45 were selected by the Postech Aptamer Initiative. The aptamer filter in which aptamers attached to beads were bound to leukocytes and removed by magnetic field was developed. Filtration of 14 units of leukoreduction-red blood provided by Korean Red Cross Blood Services was performed using aptamer filters. Leukocyte removal rate and red cell recovery rate were evaluated and bacterial culture was performed. Results: After filtration using the aptamer filters, 45.6% of leukocytes were additionally removed and the red cell recovery rate was 92.8%. No growth in the bacterial culture was observed. Conclusion: In order to apply the cell depletion technique utilizing an aptamer to blood filter system, we developed and evaluated the aptamer filter system. Through improvement of the binding efficiency of the aptamer and the filtering process, and application of the various aptamers for other different cells, we suggest that this technique can be applied in the clinical area, such as a substitution for the irradiation process for TAGVHD prevention.

Phosphorus Removal Characteristic of the Aluminum (III)-loess Composite (알루미늄-황토 복합체의 인 제거 특성)

  • Shin, Gwan-Woo;Kim, Jin-Sik;Kim, Keum-Yong;Lee, Sang-Ill
    • Journal of Korean Society of Environmental Engineers
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    • v.33 no.7
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    • pp.530-535
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    • 2011
  • In this work, the adsorption characteristic of the composites by adding loess with aluminum ("Al-loess") and Loess with lanthanum ("La-loess") which have been developed to effectively remove phosphorus, the substance which causes the eutrophic lake has been evaluated. According to the result of the work, as the amount of aluminum or lanthanum put in 1g of loess increases, the combined amount also increases accordingly. When the loess with no aluminum or lanthanum attached was used, the rate of removing phosphorus was different in comparison with the case of using the composites of 0.5, 1 and 2 mg of aluminum and 0.5, 1 and 3 mg of lanthanum in each gram of loess. It was observed the amount required to remove 1 mg $PO_4^{3-}$-P/L of phosphorus completely is approximately 2 to 10 times less for the composite of Al-loess than loess alone. Also, in case of the composite of La-loess, the amount was decreased by about 1.5 to 10 times. In order to observe the rate of adsorption phosphorus with Al-loess and La-loess, the composites were used for the observation up to three times by water washing. As a result, the water washing of the composite did not affect phosphorus removal. According to the effect of pH, there is a high rate of removing phosphorus in the pH range of 5~8. It seems that the developed composite will effectively remove phosphorus when it is spread in the natural water system. Also, since Al-loess and La-loess composites are rapidly precipitated within 30 minutes, it is stabilized quickly at the bottom of the eutrophic lake and becomes responsible for the removal of phosphorus in water and eluted from the water and the sedimentary layer.

Estimation of Characteristics Treatment for Food Waste with Blast Volume and Preheating of Air using Bio-Drying Process (Bio-drying 공법 활용 공기 투입 및 예열에 따른 음식물류 폐기물 분해 특성 평가)

  • Park, Seyong;Lee, Wonbea
    • Journal of the Korea Organic Resources Recycling Association
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    • v.30 no.4
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    • pp.15-25
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    • 2022
  • In this study, the efficiency of treatment of moisture and organic matter in food waste was analyzed according to the air blast volume and preheating using the bio-drying method. Te mount of air blast volume and preheating were determined by the evaluation of temperature and CO2 during food waste treatment using the bio-drying method. As a results, the increase in the air blast volume increased the moisture removal efficiency and removal rate, but, lowered the temperature inside the bio-drying by the decease in microbial activity. In order to maintain the activity of microorganisms, it was estimated that it was necessary to inject an appropriate air blast rate according th the properties of the food waste. In this study, the injection of air blast volume at 15L/min was optimal. It was evaluated that the organic matter and water removal rates according to the presence or absence of air preheating, the organic matter removal rate and water removal rate increased by 3-5% when air preheating was not performed. Also, there was no internal aggregation caused by the generation of condensate inside the bio-drying. Therefore, for effective bio-drying of food waste, it is necessary to maintain an appropriate air blast volume to maintain microbial activity, and it is considered that injection through preheating of air is required.

Enhancement of Coagulation and Flocculation Efficiencies by Ultrasonic Chemical Spray Nozzle I (초음파 약품분사노즐을 이용한 응집효율 향상 I)

  • Kim, Jin-Kook;Cho, Soon-Haing;Ha, Dong-Yun;Koh, Jae-Seok;Kim, Yong-Hyun;Choi, Seung-Chul
    • Journal of Korean Society of Environmental Engineers
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    • v.27 no.1
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    • pp.52-58
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    • 2005
  • To establish low-cost and high efficiency water treatment process, feasibility of applying ultrasonic spray nozzle for chemical injection was evaluated. Ultrasonic spray nozzle was manufactured using piezoelectric ceramics. Treatment efficiencies of contaminants by ultrasonic spray nozzle were compared with conventional chemical mixing such as back-mixing. It was found out that the rate of chemical diffusion rate by ultrasonic spray nozzle was faster than by back-mixing method. Removal efficiencies of various contaminants, such as turbidity, organics and microorganism by ultrasonic spray nozzle were also higher than by back-mixing method. By adapting ultrasonic spray nozzle in coagulant injection process, it can be prevented that the decline of treatment efficiency by coagulant overdose. The amount of coagulant can be reduced by applying ultrasonic spray nozzle in water treatment. Along with these advantages chemical mixing chamber is not required if ultrasonic spray nozzle is adapted. From these results, it can be concluded that chemical injection by ultrasonic spray nozzle is an economical and highly efficient device for coagulant mixing.

Evaluation of Physical Property on EM Media for Water Treatment (수처리용 EM 담체의 물리적 특성 평가)

  • Bae, Su-Hyun;Ra, Deog-Gwan
    • Journal of the Korean Society for Environmental Technology
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    • v.19 no.6
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    • pp.493-502
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    • 2018
  • The purpose of this study was to develop EM media for water treatment and to remove nitrogen and phosphorus which cause water algae boom in water system. The ideal mixing ratio of raw material such as clay: zeolite: vermiculite: activated carbon for manufacturing the EM media was 10: 2.5: 0.1: 2, and the calcination temperature was $700^{\circ}C$. The comparison of the physical properties of manufactures using distilled water and EM activated liquid as the material mixture are as follows. Porosity and density of EM media were 39.98 % and $1.13kg/m^3$, adsorption efficiencies of nitrogen and phosphorus were 69.3 % and 38.9 %. In contrast, porosity and density of distilled water media were 37.80 % and $1.11kg/m^3$, and adsorption efficiencies of nitrogen and phosphorus were 62.5 % and 37.8 %. The adsorption rate of nitrogen and phosphorus in the EM media was higher than that of the distilled water made one by 6.8 % and 1.1 %, respectively. The adsorption characteristics of the media to nitrogen and phosphorus could be expressed by the Freudlich adsorption isotherm. The change of calcination time did not affect the adsorption efficiency of phosphorus and nitrogen when EM media was formed, but it was considered that it affects the strength of media. Nitrogen removal efficiency was the best record in 4 hours of calcination time and 3 hours of calcination time in phosphorus removal efficiency.

Development of Automatic External Biphasic Defibrillator System II (Biphasic 자동형 제세동기 시스템 개발 II)

  • 권철기;정석훈;방경섭;채종필;변길호;김응주;박희남;김정국;김영훈
    • Proceedings of the IEEK Conference
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    • 2003.07c
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    • pp.2761-2764
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    • 2003
  • 본 논문에서는 개발된 biphasic 자동형 제세동기 시스템의 임상적 효용성을 동물실험을 통하여 검증하였다. 개발된 제세동기 시스템은 기존의 monophasic 제세동기와는 달리 낮은 에너지로 세동을 제거하는 biphasic 형으로, 이미 실험실 환경의 테스트를 통해 시스템의 안정성과 알고리즘의 탁월한 검출 능력이 확인되었다. 시스템의 임상적 안전성 및 효용성을 확인하기 위하여 8마리의 돼지를 사용하여 시스템의 적절한 세동 검출 및 세동제거능력을 실험하였고, 그 후 시스템의 효용성을 향상시키기 위한 연구로 같은 양의 에너지를 다른 전압 레벨에서 방전시켜 이에 따른 제 세동 효율을 조사하고, 또한 세동 신호의 규칙성과 방전시점에 따른 제 세동 효과를 평가하였다.

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A Study on the Enhanced Time Domain Aliasing Cancellation Transform of the AC-3 Algorithm (AC-3오디오 알고리듬의 시간축 영역 에일리어징 제거 변환부 성능향상에 관한 연구)

  • 김준성;강현철;변윤식
    • The Journal of the Acoustical Society of Korea
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    • v.19 no.2
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    • pp.13-18
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    • 2000
  • This paper presents the result of a technique to enhance TDAC in the AC-3 algorithm. To reduce block boundary noise without decreasing the performance of transform coding, We propose new special windows which improve the defect of the AC-3 algorithm that could not properly cancel aliasing in the transient period. In addition, a fast MDCT calculation algorithm based on a fast Fourier transform, is adopted.

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유류 오염 토양 복원을 위한 Biopile 적용성 연구

  • 조미영;김무훈;이두명;최우진;최진규
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 2003.04a
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    • pp.326-329
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    • 2003
  • 본 연구에서는 유류 오염 토양의 복원에 효율적인 것으로 나타난 Biopile 공법을 오염 토양에 적용하였을 경우, 토양의 생물학적 복원이 가능한지 여부를 평가하고자 하였다. 45일간 의 Biopile 실험 결과, 공기 주입 및 영양분 주입 후 TPH의 감소율이 최대 64.75 %까지 나타났다. 또한 공기만을 주입하였을 경우에도 제거율이 약 33 %를 나타내었다. TPH가 6,000 mg/kg인 인공 오염 토양을 사용하여 Biopile 공법을 적용하였을 경우에는 30일 반웅 후 43.46 %의 높은 제거율을 나타내었다. 오염 토양의 균주를 순화/분리 하였을 때 오염 토양 내에 고 활성의 유류 분해 미생물이 확인되었으며, 이들의 유전자 역시 확인되어 자체적으로 생물학적 분해능을 가지고 있는 토양으로 나타났다.

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Performance Analysis of Equalizer for Next Generation DSRC with OFDM System (OFDM 방식의 차세대 단거리 전용통신시스템에서 등화기의 성능 분석)

  • Kim Man-Ho;Kang Heau-Jo
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2006.05a
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    • pp.145-148
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    • 2006
  • 본 논문에서는 지능형 교통망 시스템 서비스에 사용되는 5.8GHz 대역에서 OFDM을 이용한 단거리 전용 통신 시스템을 제안하고 제안 시스템의 성능을 평가하고 이를 분석하였다. 무선 다중경로 채널에서 데이터를 고속으로 전송할 경우, 신호는 페이딩, ISI(inter-symbol interference) 등의 영향으로 높은 에러율을 가지게 된다. OFDM 방식은 보호구간을 사용해 채널의 ISI를 제거하므로 일반적으로 등화가가 필요 없으나, OFDM 각 심볼 주기마다 보호구간의 사용은 채널 사용 면에서 매우 비효율적이 된다. 따라서 채널의 지연화산이 커질 경우, 보호구간만으로는 ISI를 완전히 제거할 수 없으며, 성능 개선을 위하여 등화기가 필요하게 된다. 본 논문에서 제안된 시스템에서는 ITS 권고 주파수 대역인 5.8GHz에서 국제 표준화 규격인 IEEE 802.11a 근거하여 OFDM 시스템을 모델링 하였으며, 단일 탭 등화기를 적용하여 제안 시스템을 시뮬레이터 기법에 의하여 성능을 비교 분석하였다.

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A Study on Memory Deduplication for Improvement of Memory Efficiency in Virtualization Environment (가상화 환경에서 메모리 효율성 향상을 위한 메모리 중복제거 연구)

  • Cho, Youngjoong;Lee, Seho;Eom, Young Ik
    • Proceedings of the Korea Information Processing Society Conference
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    • 2013.11a
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    • pp.21-22
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    • 2013
  • 가상화 기술은 하드웨어 위에서 여러 운영체제를 동작시키면서, 시스템의 활용률을 극대화 시키는 기술이므로 여러 분야에서 각광받고 있다. 가상화는 시스템 위험성 전파 등을 줄임으로써, 보안 노출을 막는 등 여러 장점들이 있다. 하지만, 게스트머신에서 하이퍼바이저로의 잦은 스위치는 가상화 성능을 떨어트린다. 또한, 다수의 가상머신에서 공유될 수 있는 페이지들에 대한 메모리 중복 문제도 존재한다. 우리는 가상화 환경에서 VMEXIT를 줄이고, 메모리를 절약할 수 있는 메모리 중복제거 기술을 제안하고, 이를 정성적으로 성능 평가를 진행하였다.