• Title/Summary/Keyword: 정이식

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A Tools for Specification of Real-time Property centric Java Virtual Machine Components (실시간 속성 중심의 자바가상머신 명세도구의 설계 및 구현)

  • Ko, Jong-Won;Song, Young-Jae
    • Proceedings of the Korea Information Processing Society Conference
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    • 2004.05a
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    • pp.257-260
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    • 2004
  • 임베디드 시스템에 탑재될 자바가상머신을 기능별 모듈로 컴포넌트화 하여 이식될 플랫폼의 요구사항에 맞추어 재구성한다면 컴포넌트 기술의 장점인 소프트웨어의 재사용과 재구성을 통한 빠르고 신뢰성있는 자바가상머신 개발이 가능하다. 이러한 자바가상머신 컴포넌트 재구성을 위한 컴포넌트 모델의 정의 및 명세를 위한 지원도구가 필요하며, 명세도구의 지원 하에 보다 시각적인 컴포넌트 구성 및 각 명세요소 정의를 바탕으로 한 자바가상머신 컴포넌트의 재구성에 요구되는 여러 제약조건이나 각 컴포넌트 간의 관계정의 등이 명세 되어질 수 있다. 또한 임베디드 시스템이 가지는 실시간 속성에 대해서 정의하여 이를 명세도구를 통해서 속성명세 및 설계 시에 예측성을 지원하기 위한 WCET 계산이나 우선순위 정의 등을 명세할 수 있다. 따라서, 본 논문에서는 명세방법을 제안하고 실시간 속성 중심의 자바가상머신 컴포넌트 명세도구를 설계하고 구현하였으며, 기존에 제안된 내장형 실시간 컴포넌트 개발 도구와 비교하였다.

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Development of nuclear Transfer Embryos using Somatic Cell Nuclei from Korean Native Cattle (Hanwoo) with High Genetic Value (고능력 한우 종모우 체세포를 이용한 핵이식 배아의 발달에 관한 연구)

  • Park, S. W.;M. R. Shin.;Kim, Y. H. .;H Shim;Kim, N. H.
    • Korean Journal of Animal Reproduction
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    • v.25 no.1
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    • pp.51-61
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    • 2001
  • This study was conducted to determine developmental ability of reconstructed embryos by nuclear transfer using somatic cell of Korean bull with high genetic value. Fibroblast cells obtained from ear biopsy of the bull were cultured in Dulbecco's Modified Eagle's medium (DMEM) at 37$^{\circ}C$ in air containing 5% $CO_2$. The cummulus-oocyte complexes were collected from slaughterhouse and were matured in vitro for 20 h in TCM 199 culture medium and the oocytes were then enucleated in modified phosphate buffered saline with cytochalasin B. Matured bovine oocytes were enucleated by aspirating the first polar body and metaphase chromatin using a beveled pipette in modified phosphate buffered saline. The ear fibroblast cells were fused into enucleated oocyte by electrical stimulation. The reconstructed oocytes were activated with ionomycine and 6-dimethylaminopurine, and then cultured in CR1aa medium for 7.5 days. Out of 524 bovine eggs reconstructed by nuclear transfer 65.6%(277/422) embryos were cleaved, and 30.7% (85/277) cleaved embryos were developed to the morula to blastocysts. There was no difference of developmental ability in vitro of reconstructed embryos regardless of donor cell passages. In order to determine fate of foreign mitochondria of donor nucleus, the Mito Tracker stained cells were fused into enucleated oocytes. The donor mitochondria were detected early stage of embryos, but disappeared rapidly. The developmental ability of reconstructed embryos was not impaired by Mito Tracker treatments. The results indicate that viable reconstructed embryos can be producted by nuclear transfer using somatic cell of Korean bulls.bulls.

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Comparison of Multidetector Computed Tomography with Coronary Angiography for Evaluation of Coronary Artery Bypass Grafts (관상동맥조영술과 MDCT를 이용한 관상동맥 이식편의 비교평가)

  • Yoo, Byung-Su;Shin, Yoon-Cheol;Kim, Kun-Il;Kim, Eung-Jung;Chee, Hyun-Keun
    • Journal of Chest Surgery
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    • v.39 no.1 s.258
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    • pp.42-47
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    • 2006
  • Background: The new Multidetector Computed Tomography (MDCT) is useful in visualization of complex coronary artery anatomy. We investigated usefulness comparing of invasive coronary angiography with noninvasive MDCT in judgment of functional degree of coronary arteries grafts after coronary artery bypass graft operation. Material and Method: We analyzed the patency of 52 conduits from 15 patients whom consented to take both 32 Channel MDCT and coronary angiography from November 2003 to November 2004. Comparisons were performed for sensitivity, specificity, positive prediction value and negative prediction value between coronary angiography and 3 dimensional reconstruction image using MDCT. Result: The average graft used was 3.4 $\pm$ 0.8 per patient. Average heart rate during MDCT was 86/minute (Range, 60$\∼$110/minute) without administration of $\beta$-blocker. All patients could hold breath as much as necessary. The average graft patency obtained through corollary angiography was 96.2$\%$. In MDCT group, the sensitivity, the specificity, the positive predictive value and the negative predictive value for diagnosis was 100$\%$, 98.0$\%$, 100$\%$ and 66.6$\%$ respectively. Conclusion: The effectiveness of 32 Channel MDCT may be compared to coronary angiography in grasping about patency and bloodstream of graft conduits after coronary artery bypass graft. Also MDCT has the advantage of noninvasiveness and inexpensiveness compared to coronary angiography.

Compression Plate Fixation with Autogenous Bone Graft for Humerus Shaft Nonunion (상완골 간부 불유합에 대한 금속판 고정 및 자가골 이식술)

  • Cho, Chul-Hyun;Song, Kwang-Soon;Bae, Ki-Cheor;Kim, In-Kyoo;Kwon, Doo-Hyun
    • Clinics in Shoulder and Elbow
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    • v.12 no.1
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    • pp.33-37
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    • 2009
  • Purpose: To evaluate the results of the compression plate fixation and autogenous bone graft in the management of humerus shaft nonunion. Materials and Methods: Eighteen cases were treated for humerus shaft nonunion using compression plate fixation and an autogenous iliac bone graft. The mean follow-up period was 28 months. Bony union was confirmed from the serial radiographs and the clinical outcomes were assessed according to ASES scoring system. Results: In 12 cases of initial plate fixation, the causes of nonunion were 6 cases of inadequate plate length, 2 with a broken plate, 2 with screw loosening, 1 infection and 1 noncompliance of a psychiatric patient. In 3 cases of initial intramedullary fixation, the cause of nonunion was a distraction of the fracture site. In 3 cases of external fixation, the cause of nonunion was inadequate fixation. All cases showed bony union after an average of 24 weeks. The clinical outcomes were 11 excellent, 6 good and 1 fair. Conclusion: In the treatment for nonunion, compression plate fixation with autogeneous bone graft after complete removal of the fibrous and necrotic tissue is believed to give satisfactory results.

Changes of Kidney Injury Molecule-1 Expression and Renal Allograft Function in Protocol and for Cause Renal Allograft Biopsy (이식신 계획생검 및 재생검에서 Kidney Injury Molecule-1 표현과 이식신 기능 변화)

  • Kim, Yonhee;Lee, A-Lan;Kim, Myoung Soo;Joo, Dong Jin;Kim, Beom Seok;Huh, Kyu Ha;Kim, Soon Il;Kim, Yu Seun;Jeong, Hyeon Joo
    • Korean Journal of Transplantation
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    • v.28 no.3
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    • pp.135-143
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    • 2014
  • Background: Kidney injury molecule-1 (KIM-1) is known as a good ancillary marker of acute kidney injury (AKI) and its expression has also been observed in acute rejection and chronic graft dysfunction. We tested usefulness of KIM-1 as an indicator of acute and chronic renal graft injury by correlating KIM-1 expression with renal graft function and histology. Methods: A total of 133 zero-time biopsies and 42 follow-up biopsies obtained within 1 year posttransplantation were selected. Renal tubular KIM-1 staining was graded semiquantitatively from 0 to 3 and the extent of staining was expressed as the ratio of KIM-1 positive/CD10 positive proximal tubules using Image J program. Results: KIM-1 was positive in 39.8% of zero-time biopsies. KIM-1 positive cases were predominantly male and had received grafts from donors with older age, deceased donors, and poor renal function at the time of donation, compared with KIM-1 negative cases. KIM-1 expression showed correlation with delayed graft function and acute tubular necrosis. In comparison of KIM-1 expression between stable grafts (n=23) and grafts with dysfunction (n=19) at the time of repeated biopsy, the intensity/extent of KIM-1 staining and renal histology at zero-time did not differ significantly between the two groups. Histologically, KIM-1 expression was significantly increased with both acute and chronic changes of glomeruli, tubules and interstitium, peritubular capillaritis, and arteriolar hyalinosis. Conclusions: KIM-1 can be used as an ancillary marker of AKI and a nonspecific indicator of acute inflammation and tubulointerstitial fibrosis. However, KIM-1 expression at zero-time is not suitable for prediction of long-term graft dysfunction.

Sex Determination of Biopsied Hanwoo Embryos by Polymerase Chain Reaction and Embryo Transfer with Sexed Blastocysts (한우 체외수정란 Biopsy 후 PCR 기법을 이용한 성 판정과 성감별 수정란의 이식)

  • 김용준;정구남;이해이;조성우;김용수;유일정
    • Journal of Embryo Transfer
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    • v.15 no.3
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    • pp.219-230
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    • 2000
  • This study was carried out to determine the factors on achieving good viability of embryos biopsied fur sexing, to investigate pregnancy rate following embryo transfer(ET) with sexed embryos, and to confirm the accuracy for the calves bort following ET with sexed embryos by polymerase chain reaction(PCR). To investigate viability of Hanwoo embryos after biopsy for sexing, fresh and frozen/thawed embryos were biopsied according to different developmental day of blastocysts, different stage of blastocysts, and different biopsy grade and the embryos themselves were incubated for 2 hours in TCM199 after microsection to be evaluated morphologically for recovery as blastocyst. The results obtained were as follows : 1. The rate of oocytes cleaved in vitro and the rate of blastocyst of the cleaved oocytes were 52.5% and 21.6%, respectively. The rate of blastocyst on day 8 was 11.2%, denoting the highest rate during whole culture period posterior to in vitro fertilization(IVF) 2. After biopsy for sexing, the viability rate of blastocyst on day 7, 8 and 9 was 75.0%, 88.4%, and 100.0%, respectively and the viability of early, mid, and expanded blastocyst after biopsy was 75.0%, 88.9%, and 91.1%, respectively The viability rate of fresh and frozen/thawed embryos was 89.9%, 71.4%, respectively. And the viability of expanded, hatching, and hatched blastocyst of frozen/thawed embryos was : 75.0%, 75.0%, and 50.0%, respectively. The viability of embryos according to biopsy grade of 10∼20%, 21∼30%, and 31∼40% was 85.7%, 91.5%, and 71.4%, respectively. 3. Pregnancy rate after transfer with biopsied embryo between flesh and frozen/thawed embryos was 22.6% and 20.0%, respectively. 4. In comparison between sex by PCR method and sex of calves born after embryo transfer, the accuracy of sex deterimination was 92.3% (12/13).

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A Case of Nonclassifiable Interstitial Pneumonia after Allogeneic Hematopoietic Stem Cell Transplantation (동종 조혈모세포이식 후 비분류성 간질성 폐렴으로 사망한 1예)

  • Jung, Ki Hwan;Sung, Hwa Jung;Lee, Ju-Han;Han, Jungho;Shin, Chol;Park, Hyung Joo;Kim, Je Hyeong
    • Tuberculosis and Respiratory Diseases
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    • v.66 no.2
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    • pp.122-126
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    • 2009
  • Despite the improvements in supportive care, early and late hematopoietic stem cell transplantation-related complications still remain a significant cause of morbidity and mortality. Pulmonary complications occur in 40-60% of patients who undergo allogeneic hematopoietic stem cell transplantation. Late-onset noninfectious pulmonary complications can occur months and even years after transplantation. Interstital lung disease has also been reported to be a late post-transplant complication. Exposure to cytotoxic drugs and/or irradiation has been implicated as a cause of pulmonary toxicity including pulmonary fibrosis. We report a case of an 18-year-old female with non-classifiable interstitial pneumonia that manifested eight and a half years after allogeneic hematopoietic stem cell transplantation. The condition worsened rapidly and the patient eventually died.

Influence of Seedling Weight on Agronomic Characters and Their Relation with Bolting in Angelica gigas Nakai (참당귀 묘 중양별 생육특성과 추대와의 관계)

  • 안상득;유창연;조동하
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.39 no.5
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    • pp.426-430
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    • 1994
  • To establish the proper size of seedling of A. gigas, different weight of seedlings were used for this study. Agronomic characters including plant height, number of leaf, leaf length, number of inflorescence, fresh weight and rate of bolting of the aerial parts, root length, root diameter, number of lateral root and root weight of the underground parts were determined and correlation coefficients among them were estimated. Growth of A. gigas showed the significant vigor for all the characters of the aerial parts along with increasing of seedling weight, but root weight in yield decreased in proportion to increasing of seedling weight due to lignification of the root tissue. When the smaller seedlings were transplanted, bolting rates decreased to about 16% as compared with the traditional size of seedlings. Correlation coefficients between aerial and root characters in A. gigas were negative, and the characters such as plant height, number of leaf, number of inflorescence and fresh weight per plant showed highly significant correlation with the rate of bolting which is one of the characters having great influence on yield.

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IMPACTION OF MANDIBULAR CANINES (매복된 하악 견치의 치험례)

  • Jung, Young-Jung;Kim, Young-Jae;Kim, Jung-Wook;Jang, Ki-Taeg
    • Journal of the korean academy of Pediatric Dentistry
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    • v.32 no.2
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    • pp.278-283
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    • 2005
  • Impaction of mandibular canine is not common, and transmigration of mandibular canine is rare. Treatment of impacted canine can be removal of physical obstacle and periodic observation, surgical exposure of impacted tooth and orthodontic traction, autotransplantation, surgical extraction. Management of impacted canine depends on existence of physical obstacle, position and direction of impacted tooth, space available for canine eruption, stage of root development. Of the two case in this report, one case involved impaction of lower canine with odontoma and dentigerous cyst that is treated by surgical exposure and orthodontic traction. The other case involved transmigration of lower canine with supernumerary teeth. It was thought difficult to treat only by orthodontic treatment, so the impacted canine was transplanted to its normal position and orthodontic treatment was conducted.

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Development and Application of Wireless Power Transmission Systems for Wireless ECG Sensors (지속적인 심장질환 모니터링을 위한 인체 삽입형 생체 센서의 무선전력전송 시스템)

  • Heo, Jin-Chul;Lee, Jong-Ha
    • Journal of the Institute of Convergence Signal Processing
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    • v.20 no.2
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    • pp.111-117
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    • 2019
  • We investigated the variations in the magnetic-field distribution and power transmission efficiency, resulting from changes in the relative positions of the transmitting and receiving coils, for electromagnetic-induction-type wireless power transmission using an elliptical receive coil. Results of simulations using a high-frequency structure simulator were compared to actual measurement results. The simulations showed that the transmission efficiency could be maintained relatively stable even if the alignment between the transmitting and receiving coils was changed to some extent. When the centre of the receiving coil was perfectly aligned with the centre of the transmitting coil, the transmission efficiency was the maximum; however, the degree of decrease in the transmission efficiency was small even if the centre of the receiving coil moved by ± 10mm from the centre of the transmitting coil. Therefore, it is expected that the performance of the wireless power transmission system will not be degraded significantly even if perfect alignment is not maintained. The results suggested a standardized application method of wireless transmission in the utilization of wireless power for implantable sensors.