• Mood & Emotion
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• v.10 no.1
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• pp.13-21
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• 2012

Suicide is a complex behavior associated with various neurobiological and psychosocial factors. It is considered that genetic polymorphism combined with environmental stress such as child-adolescent trauma make differences in neurobiological systems, which cause psychiatric disorders or pessimistic personality, impulse-aggressive behaviors, lack of judgment, and finally result in suicidal behavior. Much progress in the neurobiology of suicide has been made over the several decades. There seems to be a hereditary disposition to suicide independent of psychiatric disorder. The changes in neurotransmitters, neurohormones, neurotrophic factors, cytokines, lipid metabolisms related with their genetic polymorphism can contribute to disturbance of signal transductions and neuronal circuits vulnerable to suicide. It is likely that the main factors are dysfunctions of serotonin (5-HT) and hypothalamus-pituitary-adrenal (HPA) axis. Our understanding about the neurobiology of suicide is still limited. However, clinical practice could be assisted by neurobiological findings capable of making the detection of risk populations with higher sensitivity and the development of new treatment interventions. The settlement of biological markers in suicidal behaviors and their relationships is required.

• Korean Journal of Psychosomatic Medicine
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• v.27 no.1
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• pp.42-49
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• 2019

Objectives : Living donor liver transplantation (LDLT) is a life-saving therapy for patients with terminal liver disease. Many studies have focused on recipients rather than donors. The aim of this study was to assess the emotional status and personality characteristics of LDLT donors. Methods : We evaluated 218 subjects (126 male, 92 female) who visited Daegu Catholic University Medical Center from August 2012 to July 2018. A retrospective review of their preoperative psychological evaluation was done. We investigated epidemiological data and the Minnesota Multiphasic Personality Inventory-2 questionnaire. Subanalysis was done depending on whether subjects actually underwent surgery, relationship with the recipient, and their gender. Results : Mean age of subjects was $32.19{\pm}10.91years$. 187 subjects received LDLT surgery (actual donors) while 31 subjects didn't (potential donors). Donor-recipient relationship included husband-wife, parent-children, brother-sister etc. Subjects had statistical significance on validity scale L, F, K and all clinical scales compared to the control group. Potential donors had significant difference in F(b), F(p), K, S, Pa, AGGR, PSYC, DISC and NEGE scales compared to actual donors. F, D and NEGE scales were found to be predictive for actual donation. Subanalysis on donor-recipient relationship and gender also showed significant difference in certain scales. Conclusions : Under-reporting of psychological problems should be considered when evaluating living-liver donors. Information about the donor's overall psychosocial background, mental status and donation process should also be acquired.

• Journal of The Korean Society of Integrative Medicine
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• v.2 no.4
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• pp.29-40
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• 2014

Purpose : Analyze the types of hospitalization for mental illness of mental health law, and the contents of hospitalization for legal guardians. Method : Review the previous studies from the provisions and academia of the current legislation such as the Mental Health law and the Habeas Corpus law conducting research. Result : Mental health law and habeas corpus law appears the problem in terms of current legislation. The problem of the scope and priorities of legal guardians, and the period of hospitalization, and economic issues appear in the mental health laws. Conclusion : must a lively discussion for the development of hospitalization for legal guardians. also necessary to switch the social awareness for mental illness patient.

• Electronics and Telecommunications Trends
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• v.19 no.3 s.87
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• pp.107-116
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• 2004

지금까지의 정보통신 서비스는 사용자에게 필요한 정보를 제공하거나 사용자와 사용자를 연결해주는 통로로서의 서비스를 제공하여 왔으나, 유비쿼터스 컴퓨팅과 유비쿼터스 네트워크 기술을 기반으로 한 유비쿼터스 서비스는 사용자가 처한 상황에 기반하여 정보 제공은 물론 필요한 행위까지도 제공하여 사용자의 욕구에 가장 근접한 서비스 제공에 초점을 두는 컨시어지형 서비스가 될 것이다. 이러한 서비스는 사용자의 기호 및 상태, 또는 상황 등의 다양한 정보에 근거하여 서비스를 제공할 수 있어야 하며, 이를 위한 효과적인 접근 방법으로는 사용자의 다양한 정보를 각각의 대리자에게 처리를 하게 하는 멀티 에이전트 기술일 것이다. 본 연구에서는 음악이나 그림을 활용하여 신체적, 정신적 질환을 치료하는 음악 치료나 그림 치료인 Art-Therapy를 유비쿼터스 서비스의 구현 사례로 기술한다. 사용자의 신체적 또는 정신적 상태 및 환경 정보를 센서를 활용하여 측정하고 그 측정된 데이터에 근거하여 사용자의 상태를 판단하고 이에 따라 음악 및 미술 작품을 시청각으로 제공함으로써 치료 효과를 얻는다. 본 연구에서의 Art-Therapy 서비스는 FIPA에서 제안한 멀티 에이전트 기반 구조인 에이전트 플랫폼을 기반으로 구현하였다.

• Korean Journal of Psychosomatic Medicine
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• v.26 no.2
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• pp.188-193
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• 2018

Objectives : Clozapine is a widely prescribed antipsychotic drug for schizophrenia and is known to increase the risk of cardiovascular disease due to its metabolic side effects. However, little is known about the effect of clozapine on the platelet activation, another important factor in the development of cardiovascular disease. In this study, we tried to investigate the effect of clozapine on platelet activity in patients with schizophrenia by comparing the mean platelet component (MPC) values before and after the clozapine administration. Methods : A retrospective review of medical records of patients with schizophrenia, who newly started clozapine treatment from September 1st, 2003 to April 30th, 2007 at the Department of Psychiatry, Konyang University Hospital in Republic of Korea was performed. The final statistical analysis included 14 participants. Bayer ADVIA $120^{(R)}$ system was used to measure MPC. Results : Among the 14 participants, five subjects were males (28.60%), and ten subjects were females (71.40%). The mean age of participants was $37.50{\pm}11.64years$. Average of duration of illness was $91.00{\pm}93.96months$, with the mean dosage of clozapine taken by participants at the time of the last blood test was $337.50{\pm}109.52mg$. The mean MPC measurement before and after receiving clozapine was $26.12{\pm}2.22g/dL$ and $25.14{\pm}2.08g/dL$ respectively. Wilcoxon signed rank test showed that there was a statistically significant decrease in MPC levels after clozapine administration (V=16, p=0.024). Conclusions : Decreased MPC levels after clozapine administration implies that clozapine may increase platelet activation which could have an adverse effect on the occurrence of thromboembolic disease. Our findings also suggest that careful monitoring of the risk factors of cardiovascular diseases, such as platelets activity, is necessary when administering clozapine.

• Proceedings of the Korea Information Processing Society Conference
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• 2008.11a
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• pp.137-140
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• 2008

현대 사회는 육체적·정신적 활동을 많이 요구하게 되며 이러한 현상으로 스트레스의 증가와 이유없는 증후군의 발병이 점차 확대되고 있다. 특히 스트레스로 인한 피로의 누적으로 인체의 혈액 농도 및 순환에 영향을 끼치게 되며 이로 인해 신장의 상태가 악화될 수 있다. 따라서 신장의 이상 유무를 조기에 판단하여 적절한 조치를 취하는 것이 무엇보다 중요하다. 이를 위해 본 논문에서는 신장 질환을 앓고 있는 환자와 정상인을 대상으로 피실험자 집단군을 각각 구성하고 음성 정보의 형태학적 분석과 수치학적 분석을 실험으로 출력하고 결과값에 대해 비교·분석을 행하고자 한다. 최종적으로 실험을 통해 신장과 음성과의 관계를 정립하고자 한다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.7 no.2
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• pp.203-212
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• 1996

In this thesis, we investigate the psychosocial variables within the family environments of Attention Deficit Hyperactivity Disorder with (ADHD+CD/ODD) or without (ADHD) externalizing symptoms. The subjects in this research were 86 boys and girls(aged range 6 to 14 years) consisted of 20 ADHD, 22 comorbid ADHD(ADHD+CD/ODD) and 44 normal control group(NC). We have collected data on children and their mothers. The psychosocial variables included in the analysis are socioeconomic status, parent's educational level, life stress event, and the rate of psychiatric disorders in relatives. The self-reported questionnaires marital discord(MAS), parenting stress(PSI), and parenting attitute(MBRI) completed by mothers. The results indicated that ADHD+CD/ODD is supposed to have higher level of family adversity suggested by the lower SES, lower parental educational level, higher life stress events, and more psychic disorders in relatives compared with ADHD or normal control group. In MAS, ADHD+CD/ODD group has significantly the lowest scores on each factor of the measure of marital adjustment. Parents of ADHD+CD/ODD are much more likely to have positive parenting stress when compared with the parents of ADHD. Especially, mothers of ADHD+CD/ODD have the lowest tendency in the mean score on affective, accepted attitudd. In an inapropriate parenting attitude perceived by children, father of ADHD+CD/ODD have the most negative, contradictory attitude and mothers of ADHD+CD/ODD have the most restrictive, negative and contradictory attitude.

• Proceedings of the Korea Information Processing Society Conference
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• 2019.10a
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• pp.1151-1152
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• 2019

발달 장애는 신체 및 정신이 해당하는 나이에 맞게 발달하지 않은 상태로, 다른 아동에 비해 신경정신과적 질환 발생 확률이 높기 때문에 발달장애 아동의 치료는 매우 중요하다. 그러나 주관적 판단에 의해 이루어지는 기존 작업치료의 경우, 정량적 성과 지표를 확인하기 힘들고 대상자 스스로 지속적으로 진행하기에 한계가 있다. 본 연구에서는 치료 모델을 가상 공간상에 구현하여 공간에 구애받지 않고 치료를 진행할 수 있으며, 수행 결과에 대한 자료를 정확하고 지속적으로 기록하며 확인할 수 있도록 하였다. 또한, AI 스피커를 통해 치료에 대한 피드백을 줌으로써, 대상자 스스로 실시하여 치료자의 개입을 줄여 심리적 부담을 덜어 더욱 정확한 수행이 이루어지도록 하였다.

• Korean Journal of Health Psychology
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• v.14 no.3
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• pp.579-596
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• 2009

This study aimed to develop the Korean tool of competency to consent to psychiatric treatment and to analyze the reliability and validity of this tool. Also the developed tool's efficiency in determining whether a patient possesses treatment consent competence was checked using the Receiver Operating Characteristic curve and the relevant indices. A total of 193 patients with mental illness, who were hospitalized in a mental hospital or were in community mental health center, participated in this study. We administered a questionnaire consisting of 14 questions concerning understanding, appreciation, reasoning ability, and expression of a choice to the subjects. To investigate the validity of the tool, we conducted the K-MMSE, insight test, estimated IQ, and BPRS. The tool's reliability and usefulness were examined via Cronbach's alpha, ICC, and ROC analysis, and criterion related validation was performed. This tool showed that internal consistency and agreement between raters was relatively high(ICC .80~.98, Cronbach's alpha .56~.83)and the confirmatory factor analysis for constructive validation showed that the tool was valid. Also, estimated IQ, and MMSE were significantly correlated to understanding, appreciation, expression of a choice, and reasoning ability. However, the BPRS did not show significant correlation with any subcompetences. In ROC analysis, full scale cutoff score 18.5 was suggested. Subscale cutoff scores were understanding 4.5, appreciation 8.5, reasoning ability 3.5, and expression of a choice 0.5. These results suggest that this assessment tool is reliable, valid and efficient diagnostically. Finally, limitations and implications of this study were discussed.

• Journal of Korean Academy of Nursing
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• v.27 no.4
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• pp.727-739
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• 1997

The purpose of this study was to present an effective nursing intervention for helping the patients of mental illness by determining the effect of nursing-logotherapy on purpose in life and finding meaning, and hope of the patients of mental illness by developing and applicating program of nursing-logotherapy The data was collected from March to September in 1995, and its subjects were the patients of mental illness who was appropriate to the standard of this study among the patients of mental illness who hospitalized into Neuro-Psychiatric ward of M. and B. hospital located in Pusan area. They were all 60 subjects, thirty of them for an experimental group and the rest for a control group. The research design was an equivalent control group pre-test and post-test design as an quasi-experimental research and the conceptual frame- work was an interpersonal model. The data analysis was computerized by using SP-SS/PC$^{+}$ and hypothesis testing was done with 2-way ANCOVA and simple correlation. Results were summarized as follows : 1. There were significant changes of purpose in life and finding meaning in an experimental group be-fore and after treatment and a control group be-fore and after. 2. There were significant changes of hope in an experimental group before and after treatment and a control group before and after. 3. The positive correlation between purpose in life and finding meaning and hope of the patients of mental illness were observed. Consequently, nursing-logotherapy could significantly increase the purpose in life and finding mean-ing, and of hope, so it could be said an effective nursing intervention for helping the healing of the patients of mental illness.s.