• Journal of Korea Water Resources Association
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• v.40 no.9
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• pp.735-742
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• 2007

In this study, a methodology which is based on segments and minimum outsets to estimate the reliability of a real water distribution system efficiently and accurately is suggested. The current reliability assessment models based on minimum cutset consider a pipe as only area impacted by a pipe failure which incurs underestimation of pipe failure impact. In contrary, the suggested methodology adopts "segment" and "unintended isolation" with the hydraulic pressure failure area to define the actual service interruption area in a water distribution system due to a pipe failure, which is different from the Previous reliability estimating methodologies. In addition, a minimum cutset is defined as a single segment incurring abnormal operating conditions and the success mode approach is used to account for the probability of multiple failure combinations of minimum outsets. The model considers numbers and locations of on-off valves when the service interruption area is defined. Once the methodology is applied to a real water distribution system, it is possible to define actual service interruption areas and using the defined areas, the reliability of the water distribution system is estimated reliably, compared with the previous reliability assessment methodologies.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.6
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• pp.494-502
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• 2017

This study examined the change in the students' perception of infection after school education. A self-reported questionnaire was filled out by 300 dental hygiene students in Kangwon from December 3 to December 4, 2016. The contents of the questionnaire included the general characteristics (5 items), infection-related selection (2 items), infection control recognition (5 items), and infection control behavior (10 items). The data were analyzed by frequency analysis, t-test, one way ANOVA, Chi-square test, and hierarchical multiple regression analysis using SPSS 24.0. The Cronbach's Alpha was 0.941 and 0.658, respectively. The school year and hospital practice experience had some influence on the change in infection recognition. A total of 127 students (62.6%) who had experience in practicing in hospitals knew more about antibodies. Hand washing was the highest in personal protection, followed by masks. The selection of the infectious control education method showed that the practical training class was high irrespective of the hospital practice experience, and the perceptions of patient-related infections were the greatest explanatory factor in perception after education.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.4
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• pp.423-432
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• 2018

The purpose of this study was to provide basic data to promote health in middle-aged Koreans (40-59 years old) by understanding health behaviors that affect high-density lipoprotein (HDL) cholesterol level among various health behaviors. In a national health and nutrition survey, raw data combined on a total of 7,406 persons, IV-3 (2009), V-1 (2010), V-2 (2011), V-3 (2012), and VI-1 (2013), were selected as the final analysis subjects. HDL cholesterol was divided into two groups: less than 40 mg/dl and more than 40 mg/dl. The results of multiple logistic regression analysis were as follows: OR=3.916 for males, OR=3.439 for normal than low weight, OR=7.336 for obesity than low weight, OR=1.629 for alcohol consumption, OR=1.498 for smokers, OR=1.426 for don't practice moderate physical activity, OR=1.264 for no walking exercise, OR=1.510 for carbohydrates normal intake than low intake, OR 1.787 for carbohydrates over intake than low intake when HDL cholesterol increased from 40 mg/dl to less than 40 mg/dl. Korean middle-aged high-density lipoprotein (HDL) cholesterol levels should be increased to maintain proper health through aerobic exercise, smoking cessation, proper drinking habits, obesity relief, healthy eating out, and healthy food choices. This requires continuous publicity and education within the community, and a social environment should be built that enables health behavior to be practiced in daily life.

• Proceedings of the Korea Water Resources Association Conference
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• 2011.05a
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• pp.433-433
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• 2011

수자원 계획 및 관리를 위한 지표 자료로서 일유량은 매우 유용하기 때문에 정확한 일유량 산정의 문제는 매우 중요하다. 그러나 우리나라의 경우 조석이나 배수 갑문 혹은 보 등에 의한 배수 영향으로 인해 수위-유량관계곡선식만으로 정상적인 유량산정이 어려운 지점이 다수 존재한다. 특히, 한강대교 지점과 같이 조석영향 구간에서 수위-유량관계곡선식에 의해 산정된 일유량은 자료에 대한 곡선식의 적합도 문제로 그 정확도가 매우 낮았다. 최근 자동유량측정에 의해 시간단위 이하의 실시간 유량이 생산되고 있고 이를 이용하여 일유량을 환산하고 있어 과거에 비해 보다 정확한 일유량 산정이 가능해 졌다. 그러나 신뢰도 있는 일유량을 안정적으로 제공하기 위해서는 보다 다양한 조건을 고려한 비교 검증 연구가 요구되는 실정이다. 이러한 배경에서 본 연구에서는 한강대교 지점과 같이 조석영향을 받는 지점의 일유량 산정방법 및 산정개념에 따른 유황의 차이와 적정성을 평가하여 보았다. 각 산정방법 및 산정개념 별로 산정된 일유량을 통해 유황을 산정하여 한강대교 지점의 일유량 산정방법에 대한 적정성을 평가하고 적절한 유황산정을 위한 목적별 대안을 제시하였다. 산정방법 별로는 기존의 수위-유량관계 곡선식으로 변환된 자료, 자동유량측정자료, 그리고 자동유량측정자료에서 조석성분을 제거한 순수 유출성분자료를 이용하여 일유량을 산정하였고, 이를 이용하여 산정된 유황에 대한 비교 분석을 실시하였다. 수위-유량관계곡선식에 의한 일유량은 수문조사연보의 자료를 이용하였고 자동유량자료를 이용한 일유량은 시자료를 평균하여 일유량으로 환산하는 방법을 사용하였다. 자동유량 자료에서 조석성분을 제거한 순수 유출성분의 추출은 웨이블릿 변환(wavelet transform)을 이용하였다. 각 방법별로 산정된 일유량을 비교한 결과 수위-유량관계곡선식에 의해 산정된 일유량이 자동 유량자료로 산정된 일유량에 비해 전반적으로 크게 나타났고, 2009년 한해 동안의 유출용적을 비교해 본 결과 18%정도 더 크게 산정되었다. 산정개념에 따른 비교에서는 조석성분 유량의 유효성 여부에 따른 유황을 비교하였으며, 조석성분 유량도 실효적 유량으로 간주한 경우 이론적 확률 분포형에 적합시켜 산정한 평균 갈수량은 15.7 ��/s(동절기 이상 거동기간인 2009년 11월 17일-12월 12일 기간을 제외하고 산정된 결과이나 불확실성은 잔존)에서 $53.2m^3/s$로 증가하였다. 따라서 유지유량의 목적상 경관용수나 생태용수가 중요한 지점으로 조석성분 유량이 이에 유효하다면, 유황산정을 위한 한강대교 지점의 일유량 산정방법은 다양한 목적에 비추어 추가적인 분석 검토가 필요할 것으로 판단된다.

• Journal of Veterinary Clinics
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• v.32 no.3
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• pp.231-234
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• 2015

This study measured the tibial plateau angle (TPA), a value that predicts cranial cruciate ligament rupture (CCLR) and a prerequisite for dynamic stabilization, in small breed dogs. The cadavers of 32 skeletally mature small breed dogs without CCLR were used to measure TPA. Differences were evaluated between males and females, left and right limbs, and among breeds. The mean TPA of all dogs was $26.13^{\circ}{\pm}2.33^{\circ}$. The mean TPAs of left and right limbs were $26.00^{\circ}{\pm}2.23^{\circ}$ and $26.26^{\circ}{\pm}2.45^{\circ}$, respectively, which was not a significant difference. The mean TPAs of male and female dogs were $26.01^{\circ}{\pm}1.57^{\circ}$ and $26^{\circ}.22{\pm}2.80^{\circ}$, respectively, which was also not significant difference. The mean TPAs in Maltese, Poodle, Shih Tzu, and Yorkshire terrier were $26.06^{\circ}{\pm}2.96^{\circ}$, $25.21^{\circ}{\pm}1.38^{\circ}$, $26.65^{\circ}{\pm}2.96^{\circ}$, and $26.27^{\circ}{\pm}1.61^{\circ}$, respectively. Differences in these means were not statistically significant. The TPA measured from this study could provide important information for further investigation of the pathogenesis of and surgical techniques for CCLR in small breed dogs.

• The Journal of Internal Korean Medicine
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• v.25 no.4
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• pp.18-24
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• 2004

연구배경 : 플라스미노겐 활성 억제인자-1 (plasminogen activator inhibitor-1; PAI-1)은 허혈성 뇌경색의 발생의 원인이 되는 섬유소 용해작용의 저하를 매개하는 인자로서, PAI-1의 작용이 촉진되면 섬유소 용해기능이 저하되어 관상동맥 및 뇌혈관질환의 발생을 증가시키게 된다. PAI-1 유전자의 촉진자(promoter) 영역에는 -675 4G/5G (4G/5G)와A -844G (A/G)의 두 개의 유전자 다형성이 존재하며, 이는 PAI-1의 유전자 전사과정에 영향을 미쳐 혈청 PAI-1의 농도를 증가시키고 결과적으로 허혈성 뇌경색의 발생확률을 높이는 작용을 하게 된다. 연구방법 : 허혈성 뇌경색으로 진단 받은 167명의 환자와 173명의 건강인의 말초혈액에서 DNA를 분리한 후 PAI-1의 4G/5G와 A/G 유전자 다형성에 대한 연쇄중합반응 및 제한효소 절편길이 다형성 (polymerase chain reaction-restriction fragment length polymorphism; PCR-RFLP) 방법을 이용하여 허혈성 뇌경색 발생과 유전자 다형성과의 관계를 비교 분석하였다. 결과 : 허혈성 뇌경색 환자에서의 4G/4G의 유전자형의 빈도는 15.0%으로 정상 대조군의 33.5%에 비해 현저하게 낮게 나타났다 (P < 0.0001). 각각의 유전자형과 허혈성 뇌경색의 발생 위험도 (odd ratio ; OR)와의 관계를 분석했을 때 4G/4G 유전자형을 가질 경우 위험도는 0.35배로 현저하게 낮아졌으며, (P < 0.0001), 5G/5G 유전자형을 가질 경우 위험도는 4.49배 로 현저하게 높아졌다 (P < 0.0001). 그러나, A/G 유전자 다형성과 허혈성 뇌경색의 발생과는 유의한 연관성을 발견하지 못하였다. 결론 : 이상의 결과로 볼 때 PAI-1 유전자의 4G/4G 유전자형은 허혈성 뇌경색의 발생 비율을 감소시키는 작용을 하는 것으로 여겨진다.

• Korean Journal of Head & Neck Oncology
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• v.21 no.2
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• pp.151-157
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• 2005

목적: 다양한 발생부위에서 발생한 두경부종양을 대상으로 3차원 입체조형치료를 시도하여 표적체적 내 선량균일성과 주변장기의 선량분포변하를 알아보고자 하였다. 대상 및 방법: 1995년 1월부터 1996년 12월까지 3차원 입체조형치료를 시행 받은 38명에 분석을 시행하였다. 3차원 입체조형 치료는 동일평면 또는 비동일평면상에서 4개에서 14개의 조사면 수로 시행되었다. 3차원 입체조형치료계획시 표적 체적에 $50{\sim}82Gy$의 선량을 처방하였고, 이하선 안구, 척수, 측두하악관절 등을 보호하고자 하였다. 3차원 입체조형치료 계획을 기존의 2차원 치료계획과 비교하기 위하여 표적체적과 주변정상자기의 선량체적히스토그램, 평균선량, 표적체적 내에서 처방선량의 $95{\sim}105%$의 선량이 분포하는 체적을 비교하였다 치료계획에서 실제 치료시까지 소용되는 비용효과를 비교하였다. 대상환자의 평균추적기간은 34개월이었다. 결 과: 3차원 입체조형시료는 2차원 치료에 비해서 표적체적내 평균선량이 평균 10% 증가하였고, 주변정장기에 조사되는 방사선량이 현저히 감소됨을 관찰할 수 있었고 표적체적에 대한 등선량 곡선 분포가 우수함을 관찰할 수 있었다. 결 론: 3차원 입체조형치료는 두경부종양에서 표적체적의 선량 균일성이 증가하였고, 주변장기의 보존이 가능할 것으로 생각되었다. 따라서 본 저자들은 3차원 입체조형치료가 두경부종양에서 국소제어율과 무질병생존율 향상에 기여할 것으로 생각하였다.

• Journal of the korean academy of Pediatric Dentistry
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• v.31 no.4
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• pp.701-704
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• 2004

In this case, we would like to discuss about the single rooted deciduous mandibular first molar. The deciduous mandibular molar of a five years old boy was shown to have a single root, bilaterally. Ordinarily, the maxilary molars have three roots and the mandibular molars have two roots. However, when the hertwig's epithelial root sheath do not invaginate properly during tooth development, root fusion can occur from the absence of root separation. Molars with fused roots not only have unfavorable crown to root ratio, but also according to many reports, have higher probability of having multiple congenitally missing teeth or dens invaginatus in the maxillary incisors, consequently requiring preventive dental treatment In addition, disorders such as ectodermal dysplasia, syndactyly, clinodactyly, bluish sclera can also be related to this condition. Root fusion is known to be of autosomal recessive inheritance. Up to date, single rooted molars have been reported several times in permanent dentitions but hardly in deciduous dentition, which is the motive for this paper.

• Korean Journal of Environmental Biology
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• v.27 no.1
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• pp.73-81
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• 2009

Population viability analysis of a Gold-spotted pond frog (Rana chosenica) population at Cheongwon-gun, Chungbuk, in South Korea was conducted and we proposed several suggestions for effective conservation and re-introduction of the species. Simulating a developed model over 1,000 times predicted that the population will exist over 30 years with a relatively low growth rate of 0.113, but with a high probability of extinction as 81.1%. Population growth and extinction probability were the most greatly depended on the rate of successful metamorphosis. In the case of outbreak of amphibian diseases such as Chytridiomycosis and Ranavirus, the population will be easily extinct within 4 years with 100% probability. In a habitat of which carrying capacity is 200, to successfully re-introduce an extinct population, it is initially needed to put 100 individuals of which 83% is males and its age structure is normal-distributed. If we additionally conducts artificial supplementation of 10% individuals every 2 years from 4 years to 10 years after initial reintroduction, the population will become a stable with 0.297 growth rate and 0.290 extinction rate. Our results are the first case of amphibian population viability analysis in Korea and could be used to develop effective conservation and re-introduction plans for endangered Gold-spotted pond frog.

• 대한방사선치료학회:학술대회논문집
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• 2005.06a
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• pp.23-26
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• 2005

Introduction: To evaluate whether modified MUPIT applicator can effectively eradicate recurrent tumor in uterine cervix cancer and reduce rectal complication after complete radiation treatment. Methods and Materials: Modified MUPIT applicator basically consists of an acrylic cylinder with flexible brain applicator , an acrylic template with a predrilled array of holes that serve as guides for interstitial needles and interstitial needles. CT scan was performed to determine tumor volume and the position of interstitial needles. Modified MUPIT applicator was applied to patient in operation room and the accuracy for position of interstitial needles in tumor volume was confirmed by CTscan. Brachytherapy was delivered using modified MUPIT applicator and RALS (192-Ir HDR) after calculated computer planning by orthogonal film. The daily dose was 600cGy and the total dose was delivered 3000cGy in tumor volume by BID. Rectal dose was measured by TLD at 5 points so that evaluated the risk of rectal complication. Result: The application of modified MUPIT applicator improved dramatically dose distributions in tumor volume and follow-up of 3 month for this patient was clinically partial response without normal tissue complication, Rectal dose was measured 34.1cGy, 57.1cGy, 103.8cGy, 162.7cGy, 165.7cGy at each points, especially the rectal dose including previous EBRT and ICR was 34.1cGy, 57.1cGy Conclusion: Patients with locally recurrent tumor in uterine cervix cancer treated with modified MIUPIT applicator can expect reasonable rates of local control. The advantages of the system are the fixed geometry Provided by the template and cylinders, and improved dose distributions in irregular tumor volume without rectal complication