• Title/Summary/Keyword: 전이성

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Fabrication of Nano-sized Core-Shell Transition Metal/Oxides by Selective Oxidation (선택적 산화에 의한 코어-쉘 구조의 전이금속/산화물 나노 입자 제조)

  • Choe, U-Seong;Choe, Seung-Mok
    • Proceedings of the Korean Institute of Surface Engineering Conference
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    • 2017.05a
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    • pp.99.2-99.2
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    • 2017
  • 전이금속 산화물은 비교적 높은 용량 (700~1000 mAh/g)을 갖기 때문에 차세대 리튬전지용 음극으로서 많은 연구가 진행되어 왔다. 나노 코어-쉘 구조의 다공성 전이금속/전이금속 산화물 구조는 높은 비 표면적의 산화물과 높은 전기전도성을 가지는 금속 코어로 구성되어 고효율 리튬전지에 적용가능하다. 본 연구에서는 구리 소재 상에 나노코어구조의 구리/코발트 입자를 전기화학적으로 석출시킨 후 구리의 산화가 일어나지 않는 전해질/전위 조건에서 코발트만 선택적으로 산화시켜 코어-쉘 구조의 다공성 전이금속/전이금속 산화물 구조를 얻을 수 있었다. 제조된 나노 코어-쉘 구조의 다공성 전이금속/전이금속 산화물 입자를 리튬전지의 음극으로 사용하여 매우 우수한 충/방전 안정성을 나타냄을 확인할 수 있었다.

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Whole Lung Irradiation for Metastatic Lung Malignancy (전이성 폐암의 전폐 방사선치료)

  • Chung, Tae-Soo
    • Radiation Oncology Journal
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    • v.2 no.1
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    • pp.87-92
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    • 1984
  • The author reviewed four cases of multiple lung metastases who were treated by whole lung irradiation alone for palliation. All patients tolerated the treatment well without complication. Two patients who had symptoms from pulmonary metastases had subjective relief of symptoms and all four patients had objective regression of lung metastases on repeat chest X-rays. Present report and review of literature support that some selected patients with multiple lung metastases can be benefited by whole lung Irradiation. However, systemic chemotherapy should be main modality of treatment for this kind of disseminated disease whenever possible.

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Expression of DNA-dependent Protein Kinase and Its Relationship with Epidermal Growth Factor Receptor Signaling in Metastatic Cancer Cell Lines (DNA-PK 및 표피성장인자수용체의 신호전달이 암전이에 미치는 영향)

  • Hwang Jee Young;Kim Sun Hee;Kang Chi Dug;Yoon Man Soo
    • Journal of Life Science
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    • v.15 no.3 s.70
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    • pp.406-414
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    • 2005
  • The genetic instability of cancer cells may be related to inappropriately activated DNA repair pathways. In present study, the modulated expression of DNA-dependent protein kinase (DNA-PK), a major DNA repair protein, in human cancer metastatic cells was tested. The expressions of Ku70/80, regulatory subunit of DNA-PK, and the Ku DNA-binding activity in various highly metastatic cell lines were higher than those in each parental cell line. Also, the expression of DNA-PKcs, catalytic subunit of DNA-PK, and the kinase activity of the whole DNA-PK complex in highly metastatic cells were significantly increased as compared to those of parental cells, suggesting that the enhanced DNA repair capacity of metastatic cells could be associated with aberrant use of DNA repair, which may mediate tumor progression and metastatic potential. Increased EGFR (epidermal growth factor receptor) signaling has been associated with tumor invasion and metastasis, and the linkage between EGFR-mediated signaling and DNA-PK has been suggested. This study showed that PKI166, the new EGFR tyrosine kinase inhibitor, modulated the expressions of Ku70/80 and DNA-PKcs and also revealed the chemosensitization effect of PKI166 against metastatic cells may be in part due to inhibition of Ku70/80. These results suggest that interference in EGFR signaling by EGFR inhibitor resulted in the impairment of DNA repair activity, and thus DNA-PK could be possible molecular targets for therapy against metastatic cancer cells.

Short Term Result of Total en Bloc Spondylectomy in Spine Tumor (원발성 및 전이성 척추종양에 대한 전 척추 절제술의 단기 추시 결과)

  • Kim, Jae-Do;Jang, Jae-Ho;Park, Chan-Jae;Chung, Jae-Yoon
    • The Journal of the Korean bone and joint tumor society
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    • v.13 no.1
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    • pp.37-42
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    • 2007
  • Purpose: Because of the anatomical characteristics, it is difficult to perform radical operation in spinal tumor. Numerous operations on primary and metastatic spinal tumor have been performed and among those total en bloc spondylectomy has produced decent clinical result. Clinical and radiological results have been analyzed based on five total en bloc spondylectomy on primary and metastatic spinal tumor. Materials and Methods: Patients included in this study were one with primary and four with metastatic spinal tumors, from June 1997 to January 2006. Two of the four were originated form kidney. One was from breast and the other one was not identified. McAfee's 4 point scale, VAS and Frankel's classification have been used as clinical assessment of pain and neurological symptoms. Clinical assessment have been conducted for every 3 months after operation including local recurrence, bone union and complications. Results: Assessment of pain decreased from average of 3 before operation to 1.6 after operation in McAfee's scale and VAS decreased from average of 9.2 to 1.6. Neurological deficit after operation improved from C to D in Frankel's category. Local recurrence has been detected on metastatic adenocarcinoma of L4 during follow up. Conclusion: Total en bloc spondylectomy is evidently useful operational method for primary and metastatic spinal tumor since it completely decompresses spinal nerves, decreases axial pain immediately and improves the quality of remaining life.

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Clinical Analysis of Metastatic Tumors of Bone - Survivorship Analysis after Bony Metastasis - (전이성 골종양에 대한 임상적 분석 - 골전이 후의 생존분석 -)

  • Kim, Kyung-Je;Kang, Ho-Seong;Kim, Yon-Il;Shin, Byung-Joon
    • The Journal of the Korean bone and joint tumor society
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    • v.7 no.4
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    • pp.133-138
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    • 2001
  • Purpose : To analyze the clinical behaviors and survivorship of metastatic bone tumors. Materials and Methods : One hundred and ninty-eight metastatic bone tumors had been diagnosed from January 1982 to December 1998. Age and sex distribution, primary cancer types. metastatic sites, duration from diagnosed of primary tumors to bony metastases and survivorship were analysed. Results : Mean age was 57(24~86) years old. Lung(32.3%) and breast(16.2%) cancers were two most common primary foci. The spines was the most common site of metastases especially lumbar region(38%). Survivorship analysis was done in one hundred and fifteen patients who had been followed up. The mean survival period was 15.3 months. The survivorship of hepatoma(7.1 Mons), lung(8.72 Mons) and renal cell(4.8 Mons)cancers was relatively shorter and breast cancer(54.1 Mons) longest. Conclusion : The mean age of metastatic bone tumors of this study was older than the past reports. The axial skeletons especially spine was predominant metastatic site. The survivorship of metastatic bone tumor decreased sharply as time goes by, so early diagnosis is clue for longer survival after bony metastases.

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A Design of a Web-based IPv6 Migration Support System (웹 기반 IPv6 전이 지원 시스템 설계)

  • 연제길;이길섭;이승종
    • Proceedings of the Korean Information Science Society Conference
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    • 2004.10c
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    • pp.346-348
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    • 2004
  • 현재, 인터넷이 정보화 사회의 핵심 인프라로 자리를 매김에 따라 사용자가 폭발적으로 증가하게 되었고, 이로 인한 주소 부족 현상이 심화되고 있다. 한편, 국방정보통신망에서도 통신대상의 증가 및 서비스 품질보장, 전술통신체계의 이동성 및 생존성 보장을 요구하고 있다. 이러한 변화는 주소부족 문제 해결, 이동성, 보안성, QoS 보장 서비스 등 다양한 기능 지원이 가능한 IPv6의 도입이 요구된다. 이에 따라 국방정보통신망에서의 IPv6 도입 전략에 대한 연구가 진행되었다. 이미 시작된 IPv6 도입 전략과 연계하여 본 논문에서는 우리 군에 IPv6로의 전이를 효과적으로 지원하기 위해 웹 기반 IPv6 전이 지원 시스템을 설계하고자 한다. 그리고 설계된 체계를 활용하여 국방정보통신망 시스템 자원을 기반으로 IPv6 전이 지원 절차에 따라 점검 자원 DB를 구축한다. 웹 상에서 IPv6로의 전이 요청 부대 실무자가 전산자원에 대한 전이절차 정보 및 예산산출 정보를 지원 받음으로써 IPv6로의 전이를 체계적이고 신속하게 지원하게 된다.

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Identification of Mariner-Like Element(MLE) Gene from Nombyx mori. (누에에서의 Mariner 유사 전이인자유전자의 동정)

  • Lee, Jin-Sung;Hwang, Jae-Sam;Kim, Yong-Sung;Suh, Dong-Sang;Kwon, O-Yu
    • Journal of Life Science
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    • v.8 no.3
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    • pp.285-293
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    • 1998
  • We have cloned an internal fragment of the putative transoisase gene of MLE in the silkworm, Bombyx mori, using PCR method with degenerative oligonucleotide primers designed to represent regions of amino acids encoding transposase. The resulting PCR clone, designed as BmoMAR, cords a partial ORF(152 a.a.) of MLE in which interrupted by five stop codons, and the sequence of its deduced amino acids showed 37% homology with Mos1, an active mariner, from Drosophila mauritiana. Furthermore, the BmoMAR exhibits nucleotide and amino acid homology with 59% and 37% from Apis mellifera and D. mauritiana 7.9 clone, respectively. This result strongly that a MLE is present in the genome of B. mori.

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Metastasizing Pleomorphic Adenoma in Right Lung -A case report - (우측 폐로 전이된 전이성 다형태 선종 -증례 보고-)

  • Chung, Won-Sang;Nam, Seung-Hyuk;Kang, Jeong-Ho;Kim, Young-Hak;Kim, Eung-Soo;Kim, Hyuck
    • Journal of Chest Surgery
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    • v.40 no.2 s.271
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    • pp.143-146
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    • 2007
  • A metastasizing pleomorphic adenoma originating from the parotid gland is a rare form of neoplasm. The neoplasm is a histologically benign, but clinically controversial entity. Herein, a case report of a pleuro-pneumonectomy of a metastasizing pleomorphic adenoma in the right lung is described. A 57-year-old man, who underwent resection of parotid gland due to a pleomorphic adenoma, presented with multiple metastases on the right lung, mediastinum, pericardium and intercostal muscle. The metastatic lesions were composed of a benign pleomorphic structure.

비즈니스 인사이드 - (주)디디피스토리, 저 전이성 잉크 세미나 개최

  • Im, Nam-Suk
    • 프린팅코리아
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    • v.13 no.10
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    • pp.84-85
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    • 2014
  • (주)디디피스토리(대표이사 박정훈)는 지난 8월 27일부터 30일까지 일산 킨텍스 전시자에서 열린 ' K-PRINT WEEK 2014'에서 '식품 및 의약품 패키징을 위한 저 전이성 잉크 세미나'를 개최했다. 이날 세미나는 Helmuth Munter Durst Phototechnik AG 라벨&패키지인쇄부문 매니저가 진행됐다.

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Multiple Pulmonary Benign Metastasizing Leiomyoma (다발성 폐 양성 전이성 평활근종)

  • Sa, Young-Jo;Sim, Sung-Bo;Yoon, Hyung-Gue;Yoo, Chang-Young;Moon, Young-Kyu;Park, Jae-Kil;Lee, Sun-Hee
    • Journal of Chest Surgery
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    • v.41 no.6
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    • pp.777-781
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    • 2008
  • Benign metastasizing leiomyoma is a rare disease that histologically shows features of a benign tumor; however it can metastasize to the lung or other organs. We report here on a case of a 53-year-old Woman with benign metastasizing leiomyoma, and she was admitted to the hospital with symptoms of coughing for 2 months; she showed multiple diffuse nodular opacities of both lungs on a chest radiograph. She had undergone hysterectomy for leiomyoma of the uterus 13 years previously. Thoracoscopic lung biopsy was performed to rule out metastatic lung cancer. The pulmonary nodules appeared benign with a very low mitotic rate and they consisted of smooth muscle cells. The pathologic findings of the pulmonary nodules were consistent with benign metastasizing leiomyoma. The patient has been followed up closely without any specific therapy.