Multiple Pulmonary Benign Metastasizing Leiomyoma

다발성 폐 양성 전이성 평활근종

  • Sa, Young-Jo (Department of Thoracic and Cardiovascular Surgery, St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Sim, Sung-Bo (Department of Thoracic and Cardiovascular Surgery, St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Yoon, Hyung-Gue (Department of Internal Medicine, St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Yoo, Chang-Young (Department of Pathology, St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Moon, Young-Kyu (Department of Thoracic and Cardiovascular Surgery, St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Park, Jae-Kil (Department of Thoracic and Cardiovascular Surgery, St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Lee, Sun-Hee (Department of Thoracic and Cardiovascular Surgery, St. Mary's Hospital, The Catholic University of Korea College of Medicine)
  • 사영조 (가톨릭대학교 의과대학 성모병원 흉부외과학교실) ;
  • 심성보 (가톨릭대학교 의과대학 성모병원 흉부외과학교실) ;
  • 윤형규 (가톨릭대학교 의과대학 내과학교실) ;
  • 유창영 (가톨릭대학교 의과대학 성모병원 병리학교실) ;
  • 문영규 (가톨릭대학교 의과대학 성모병원 흉부외과학교실) ;
  • 박재길 (가톨릭대학교 의과대학 성모병원 흉부외과학교실) ;
  • 이선희 (가톨릭대학교 의과대학 성모병원 흉부외과학교실)
  • Published : 2008.12.05

Abstract

Benign metastasizing leiomyoma is a rare disease that histologically shows features of a benign tumor; however it can metastasize to the lung or other organs. We report here on a case of a 53-year-old Woman with benign metastasizing leiomyoma, and she was admitted to the hospital with symptoms of coughing for 2 months; she showed multiple diffuse nodular opacities of both lungs on a chest radiograph. She had undergone hysterectomy for leiomyoma of the uterus 13 years previously. Thoracoscopic lung biopsy was performed to rule out metastatic lung cancer. The pulmonary nodules appeared benign with a very low mitotic rate and they consisted of smooth muscle cells. The pathologic findings of the pulmonary nodules were consistent with benign metastasizing leiomyoma. The patient has been followed up closely without any specific therapy.

양성 전이성 평활근종은 조직학적으로 양성 종양의 소견을 보이나 임상적으로 폐나 다른 장기로 전이하는 매우 드문 질환이다. 저자들은 2개월간 지속된 기침을 주소로 입윈한 53세의 여자환자에서 좌우 다발성으로 퍼져 있는 폐결절들을 가진 전이성 평활근종 1예를 경험하였다. 증례는 과거력상 13년전 자궁근종으로 전자궁적출술을 받았으며, 자궁근종은 병리조직 검사상 평활근종으로 진단되었었다. 환자는 전이성 폐암 의심 하에 흉강경 폐 조직검사를 실시하였다. 폐 결절들은 낮은 세포 분열을 보이는 양성 종양의 소견을 보이며, 평활근 세포의 다발성 결절들로 이루어져 병리학적으로 양성 전이성 평활근종과 일치하는 소견을 보였다. 환자는 현재 별다른 치료 없이 추적 관찰 중이다.

Keywords

References

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