• Proceedings of the Korea Information Processing Society Conference
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• 2008.11a
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• pp.112-113
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• 2008

유방암은 유럽과 미국을 비롯해 전 세계적으로 증가하고 있으며 최근 우리나라에서도 가장 급속하게 늘고 있는 여성암중에 하나이다. 본 연구에서는 먼저 grey level co-occurrence matrix(GLCM)을 적용하여 유방영역을 분할한 후, median filter 를 적용하여 잡음을 제거하였다. 전처리 수행 후, 2차미분 행렬을 이용할여 미소석회화 부분을 강조한 후, 가우시안 정규분포도를 적용하여 미소석회화 후보군을 검출하였다. 검출된 후보군은 8 개의 feature 들을 적용하여 미소석회화를 최종 결정하였다. 본 연구를 통해서 조기 유방암 진단을 위한 발전된 미소석회화 검출 방법을 제안하였다.

• Korean Journal of Soil Science and Fertilizer
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• v.24 no.3
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• pp.165-170
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• 1991

Effects of liming and starch application on the soil pH and mineralization of organic nitrogen were compared to control at $30+/10^{\circ}C$ incubation for six weeks in two soil types(loam, sandy loam) adjusted with 80% of field moisture capacity. 1. While soil pH was increased abruptyl one week after incubation in loam applied with lime and lime+starch, it tended to decrease at control during incubation period. Liming on sandy loam increased soil pH, and application of lime+starch together showed high pH at first week of incubation which was lowered slowly after wards. Significant changes in soil pH was not detected at control or starch application only. 2. The content of $NH_3-N$ in loam started to increse three weeks after incubation, and was maximized at fifth week. Positive correlation was shown at control during incubation period between soil pH and $NO_3-N$ content. Level of $NO_3-N$ content applied with starch or lime+starch was low compared to control. 3. The $NH_4-N$ content was high when sandy loam was applied with lime+starch together. At the first week of incubation, the $NO_3-N$ content was high at control or lime application.

• Proceedings of the Korea Information Processing Society Conference
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• 2023.05a
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• pp.681-683
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• 2023

폐암은 전 세계적으로 사망률이 가장 높은 암 질환으로, 조기 발견 및 신속한 치료를 위해서는 흉부 X-ray 영상 내 악성 결절을 놓치지 않는 것이 중요하다. 그러나 흉부 X-ray 영상은 정밀도의 한계로 진단 결과에 대한 신뢰도가 낮아, 이를 보조하는 도구의 개발이 요구된다. 기존의 폐암 진단 보조 도구는 학습 기반의 기법으로, 진단 결과에 대한 설명성(explainability)이 없다는 위험성을 갖는다. 이에 본 논문에서는 통계 분석에 기반한 결절의 석회화 여부 진단 기법을 제안한다. 제안하는 기법은 결절과 해부학적 구조물의 밝기 차 분포로부터 석회화 여부를 판단하며, 그 결과 민감도 65.22%, 특이도 88.48%, 정확도 83.41%의 성능을 보였다.

• Journal of Chest Surgery
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• v.35 no.2
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• pp.94-101
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• 2002

All kinds of tissue valves must be pretreated for the inactivation of immunologic properties and the strengthening of tissue before implantation. However, the tissue valves are gradually denatured with the calcification process and they eventually lose their functions. Recent reports have shown the existence of specific calcium binding non collagenous proteins in the calcified area of implanted biomaterials. This experiment was intended to confirm the effect of pretreatment with RGDS(Arg-Gly-Asp-Ser) tetrapeptide on the calcification of subcutaneously implanted bovine pericardium in rats. RGDS tetrapeptide has the same amino acid sequence of attachment site of specific calcium binding non collagenous proteins. Material and Method: All bovine pericardial pieces were fixed with 0.6% glutaraldehyde. The pretreatments were done using 5 different methods, groupI, with normal saline for 60 minutes, groupII, with 0.5% GRSD(Gly-Arg-Scr-Asp) tetrapeptide solution for 60 minutes, group III : with 0.5% RGDS(Arg-Gly-Asp-Ser) tctrapeptide for 30 minutes, group IV ; with 0.5% RGDS for 60 minutes, and group V : with 0.5% RGDS for 120 minutes. The pretreated bovine pericardial pieces were implanted subcutaneously at the abdominal sites of rats. 30 days after the implantation, the implanted bovine pericardial tissue were examined radiologically, biochemically, and histologically to measure the severity of calcification. Result: On the radiological examination, group I ; 68.42$\pm$3.06, group II , 64.25$\pm$5.58 showed significant difference with group III: 48.00$\pm$3.57, group IV; 43.67$\pm$2.31, and group V ; 2.58$\pm$2.47(p<0.05). There was no difference between group I and II(p=0.105). On the biochemical examination, the amount of calcium in group I was , 33.09$\pm$6.59 mg, in group II ; 28.12$\pm$5.50mg, in group III ; 25.42$\pm$7.67mg, in group Ⅵ ; 20.51$\pm$5.11mg, and in group V : 15.43$\pm$4.25mg.

• The Journal of Korean Academy of Prosthodontics
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• v.49 no.1
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• pp.16-21
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• 2011

Purpose: The purpose of this study was to investigate the bioactivity of precalcified nanotubular $TiO_2$ layer on Ti-6Al-7Nb alloy. Materials and methods: Anodic oxidation was carried out at a potential of 20 V and current density of 20 mA/$cm^2$ for 1 hour. The glycerol solution containing 1 wt% $NH_4F$ and 20 wt% deionized water was used as an electrolyte. Precalcification treatment was obtained by soaking in $Na_2HPO_4$ solution at $80^{\circ}C$ for 30 minutes followed by soaking in saturated $Ca(OH)_2$ solution at $100^{\circ}C$ for 30 minutes, followed by heat treatment at $500^{\circ}C$ for 2 hours. To evaluate the activity of precalcified nanotubular $TiO_2$ layer, specimens were immersed in a simulated body fluid with pH 7.4 at $36.5^{\circ}C$ for 10 days. Results: 1. Nanotubular $TiO_2$ layer showed the highly ordered dense structure by interposing small diameter nanotubes between large ones, the shape of nanotubes was enlarged as going down. 2. The mean length of nanotubes was $517.0{\pm}23.2\;nm$ innm glycerol solution containing 1 wt% $NH_4F$ and 20 wt% $H_2O$ at 20 V for 1 hour. 3. The bioactivity of Ti-6Al-7Nb alloy was improved with formation of nanotubular $TiO_2$ layer and precalcification treatment in $80^{\circ}C$ 0.5 M $Na_2HPO_4$ and saturated $100^{\circ}C$ $Ca(OH)_2$ solution. Conclusion: Bioactivity of precalcified nanotubular $TiO_2$ layer on Ti-6Al-7Nb alloy was improved.

• Journal of the Institute of Convergence Signal Processing
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• v.13 no.1
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• pp.6-11
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• 2012

Digital mammogram is effective for detecting the micro-calcification that is early symptom of breast cancer. In the digital mammogram, many image processing techniques have been studied for accurate diagnosis and efficient treatment of micro-calcification lesion. The wavelet based multi-scale method was mainly used to enhance the image contrast. This paper presents an advanced mammography enhancement method which is based both on the brightness and the contrast enhancement in the wavelet domain. The proposed method normalizes a dynamic range using histogram of the image. The brightness is enhanced by modifying coefficients of low frequency components, and the contrast is enhanced by coefficients of high frequency component based on the multi-scale contrast measure. The experiment results show that the proposed method yields better performance of the image enhancement over the existing methods.

• Proceedings of the Korean Society of Organic Agriculture Conference
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• 2009.12a
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• pp.285-285
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• 2009

벼 유기재배에 있어서 녹비작물을 이용하여 화학비료를 대신하고 있으나 녹비를 이용하기 위해서는 월동 전에 파종하고 이듬해 벼 이앙 전에 토양에 환원을 해야 하는 번거로움이 있다. 따라서 벼 재배 직전에 유기자재를 이용하여 화학비료를 대신하고자 했을 경우 유기자재를 전층시비와 표층시비의 차이에 따른 토양중의 이화학적 특성과 벼의 수량특성의 변화를 구명하였다. 벼 유기재배시 토양양분공급용으로 이용되고 있는 유기자재 4종을 공시하여 유기자재의 질소 성분량(7kg/10a)을 기준으로 하여 이앙 20일전에 시비방법별로 전층시비와 표층시비 2처리로 구분하여 전량 기비시비하고 경운한 다음 동진1호를 시험품종으로 하여 2년 연속 시비처리와 벼를 재배하면서 일어나는 토양의 이화학적 특성과 벼 생육 및 특성의 변화를 시기별로 조사하였다. 시험 전 토양의 화학성은 표층시비구의 염류농도, 가리와 석회의 함량이 다소 높아서 염류농도가 전층 시비구 보다 높은 조건의 토양이었다. 유기자재별 무기화 정도는 전층시비보다 표층시비를 할 때 약 20~30일 정도 빨랐다. 토양 중의유기물 잔존함량은 시비방법간의 큰 차이는 없었으나 표층시비를 할 경우 후기로 갈수록 다소 증가되는 경향이었으나, 전질소 잔존함량은 감소되었다. 토양 액상과 공극율은 전층시비>표층시비였으며, 입단 형성력도 같은 경향이었다. 토양 효소활성은 PME의 활성은 유기자재를 전층처리하였을 때 촉진되었으며, $\beta$-Glucosidase의 활성은 전층보다 표층처리시 활성이 높았다. 시비방법에 따른 벼의 수량 특성은 시비방법별로는 표층시비를 할 경우 전층시비보다 4~7%의 높은 특성을 보였으며, 관행대비 1년차에는 3~9%의 낮았으나, 2년 연속처리를 할 경우 대조구와 비슷해 지는 경향이었다.

• Applied Biological Chemistry
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• v.17 no.1
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• pp.31-41
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• 1974

This study was conducted to determine the effects of soybean cultivation on yield and other characters in a newly reclaimed soil. Four factois - (1) plant density (2) compost application (3) innoculation of nodule bacteria (Rhizobium japonicum) combined with lime application (4) NPK application-were examined in a 24 factorial experiments arranged in randomized complete block design with 4 replicates. Kangio variety was used and the results obtained are summarized as follows; (1) Dense plant population, Application of Compost and application of fertilizer (NPK) gave the yields 1.7, 1.4 and 2.1 times the check respectively. The Combinations of, dense $population{\times}compost$, dense $compost{\times}fertilizer$ (NPK), $population{\times}compost{\times}fertilizer$ (NPK), and dense $population{\times}compost{\times}nodule$ bacteria with $lime{\times}fertilizer$ (NPK) increased the yields by 2.0, 3.0, 2.6 and 5.4 times than the check respectively. But little effect on yield was noted in the treatment inoculated with nodule bacteria with lime. (2) In the case of higher yield, the increased weight of 100 seeds was found. (3) A markedly increased PH was observed in all of the plots under study after the completion of experiment. (4) The compost treatment and the ferttilizer (NPK) treatment greatly increased the organic matter, total nitrogen and the available phosphorus in the soil. (5) The variation in the grain yield appeared to have a close correlation with the content of available $P_2O_5$ in the soil.

• Journal of Chest Surgery
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• v.41 no.2
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• pp.170-176
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• 2008

Background: Bioprosthetic devices for treating cardiovascular diseases and defects may provide alternatives to autologous and homograft tissue. We evaluated the mechanical and physical conditions of a porcine pericardial bioprosthesis treated with Glutaraldehyde (GA), Ethanol, or Sodium dodecylsulfate (SDS) before implantation. Material and Method: 1) Thirty square-shaped pieces of porcine pericardium were fixed in 0.625%, 1.5% or 3% GA solution. 2) The tensile strength and thickness of these and other bioprosthesis, including fresh porcine pericardium, fresh human pericardium, and commercially produced heterografts, were measured. 3) The tensile strength and thickness of the six treated groups (GA-Ethanol, Ethanol-GA, SDS only, SDS-GA, Ethanol-SDS-GA and SDS-Ethanol-GA) were measured. Result: 1) Porcine pericardium fixed in 0.625% GA the thinnest and had the lowest tensile strength, with thickness and tensile strength increasing with the concentration of GA solution. The relationship between tensile strength and thickness of porcine pericardium increased at thicknesses greater than 0.1mm (correlation-coefficient 0.514, 0<0.001). 2) There were no differences in tensile strength or thickness between commercially-produced heterografts. 3) Treatment of GA, ethanol, or SDS minimally influenced thickness and tensile strength of porcine pericardium, except for SDS alone. Conclusion: Porcine pericardial bioprosthesis greater than 0.1 mm thick provide better handling and advantageous tensile strength. GA fixation did not cause physical or mechanical damage during anticalcification or decellularization treatment, but combining SDS-ethanol pre-treatment and GA fixation provided the best tensile strength and thickness.

• Journal of agriculture & life science
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• v.46 no.2
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• pp.83-89
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• 2012

This study was performed to determine the effect of topdressing on maintaining the quality and density of zoysiagrass. An increase in the topdressing height from 2 mm to 16 mm (2, 4, 8, and 16 mm) led to an increase in the plant heigh, fresh and dry weight of shoots, roots, and stolons. The number of shoots, stolons and concentrations of chlorophyll and carotenoid also increased with increasing topdressing height. Moreover, total concentrations of nitrogen, phosphoric acid, potassium, magnesium, and lime in shoots and roots were enhanced as topdressing height increased. Acidity and the concentrations of organic matters, total nitrogen, and exchangeable cations ($K^+$, $Na^+$, $Ca^{2+}$, $Mg^{2+}$) of topdressed soil was higher than not topdressed soil, while the amount of available phosphoric acid in topdressed soil was lower than not topdressed. The topdressed soil enhanced the growth and density of zoysiagrass, while it was a crucial factor to affect the chemical property of the soil. Optimum topdressing height was thought to be 8 mm since topdressing the soil with topdressing height of 8 mm not only improved the growth of zoysiagrass but also resulted in the highest concentration of nitrogen and organic matters in the soil.