• Title/Summary/Keyword: 전기신호측정

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Electrochemical Immunoassay based on the Dopamine-antigen Conjugate for Detecting Hippuric Acid (항원인 마뇨산에 결합된 도파민을 이용한 전기화학적 면역 분석법)

  • Choi, Young-Bong;Jeon, Won-Yong;Kim, Hyug-Han
    • Journal of the Korean Electrochemical Society
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    • v.17 no.3
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    • pp.172-178
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    • 2014
  • In this work, we describe an electrochemical immunosensor for simple, fast and quantitative detection of a urinary hippuric acid (HA). Urinary HA, of molecular weight 180 DA, is one of the major metabolites and biological indicators in toluene-exposed humans. Simple and ubiquitous monitoring of exposure to toluene is very important in occupational health care. We propose the electrochemical immunoassay based on the dopamine-antigen conjugate for detecting hippuric acid. Our electrochemical immunoassay system employs a conjugate of dopamine (DA) as an electrochemical active molecule and hippuric acid (HA) as an antigen. As an electrochemical aspect, dopamine (DA) containing two hydroxyl group can show excellent redox signal. Also, dopamine-tethered hippuric acid (DA-HA) shows the reversible redox signal in the immunoassay. The competition between HA and DA-HA generated electric signals proportional to HA concentration. The electrochemical immunoassay was performed with DA-HA on the screen printed carbon electrodes (SPCEs), and then applies the mixture antigen (HA) and HA-antibody. The electrical signals were proportional to HA in the range of 0.010~2.500 mg/mL which is enough range to be used for the point-of-care.

A geophysical survey result over a hydrocarbon contaminated site (물리탐사를 이용한 국내 유류오염지역 조사 사례)

  • Song Yoonho;Park Sam Gyu;Seol Soon Jn;Choi Seong-Jun;Chung Seung-Hwan
    • 한국지구물리탐사학회:학술대회논문집
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    • 2001.09a
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    • pp.122-140
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    • 2001
  • We have applied the geophysical survey, mainly electric and electromagnetic (EM) methods, to a test site contaminated by hydrocarbon waste disposal and local spill. The multi-frequency, moving source & receiver EM survey along with ground penetrating radar (GPR) showed a fairly good performance in detection of buried metal pipes and objects. Magnetic survey measuring vertical and horizontal gradients were so sensitive to the small metallic objects spread over the surface that it's hard to discriminate the buried pipe. We chose electrical resistivity, EM and GPR survey to examine the soil contamination. Depth slices of resistivity distribution as the results of the inversion of resistivity and EM data coincided each other and closely matched the contaminated area determined by chemical analysis of the soil samples. GPR images did not show the reflection events related with contamination plume since there are no distinct spill in this site. We inferred the contamination using the penetration depth of the GPR energy, which could be used as auxiliary information to the resistivity and EM results. We summarized the applicability of each survey methods based on this results and proposed a desirable survey scheme for the determination of hydrocarbon contaminated site.

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The Hearing Ability of Coralfish Chromis notatus to Low Frequency Sound 2. The Auditory Critical Ratio and Hearing Index (저주파음에 의한 자리돔의 청각 능력 2. 청각 임계비 및 청각능력지수)

  • 이창헌;서두옥
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.36 no.4
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    • pp.314-321
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    • 2000
  • In order to obtain the fundamental data on the auditory thresholds of fishes for catching method using low frequency sound, the auditory thresholds of coralfish Chromis notatus were measured in the presence of masking noise in the spectrum level range of 73~83dB re l$\mu$Pa/√Hz by heartbeat conditioning technique using pure tones coupled with a delayed electric shock. Critical ratios were about 23~41dB at measurement frequency, The critical ratio increased almost linearly with increasing frequency from 500Hz. The noise spectrum level at the start of masking was about 60~65dB. This suggests that hearing of coralfish is masked in the natural environment with the noise spectrum level above 60dB. The sound pressure level of which the signal sound of 300Hz is recognized by coralfish under the ambient noise is above 88dB and the critical ratio of them is above 23dB. The hearing index of coralfish with ambient noise was 81.

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Capacitively-coupled Resistivity Method - Applicability and Limitation (비접지식 전기비저항 탐사 - 적용성과 한계)

  • Lee Seong Kon;Cho Seong-Jun;Song Yoonho;Chung Seung-Hwan
    • Geophysics and Geophysical Exploration
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    • v.5 no.1
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    • pp.23-32
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    • 2002
  • Capacitively-coupled resistivity (CCR) system is known to be very useful where galvanic contact to earth is impossible, such as the area covered with thick ice, snow, concrete or asphalt. This system injects current non-galvanically, i.e., capacitively to earth through line antenna and measures potential difference in a same manner. We derived geometric factor for two types of antenna configuration and presented the method of processing and converting the data obtained with CCR system suitable to conventional resistivity inversion analysis. The CCR system, however, has limitations on use at conductive area or electrically noisy area since it is very difficult to inject sufficient current to earth with this system as with conventional resistivity system. This causes low SM ratio when acquiring data with CCR system and great care must be taken in acquiring data with this system. Additionally the uniform contact between line antennas and earth is also crucial factor to obtain good S/N ratio data. The CCR method, however, enables one to perform continuous profiling over a survey line by dragging entire system and thus will be useful in rapid investigation of conductivity distribution in shallow subsurface.

Estimation of Causal Connectivity between Cortical Areas Using Near-Infrared Spectroscopy (NIRS) (근적외선 분광법을 이용한 대뇌피질영역 간 연관성 분석)

  • Lee, Seung-Deok;Go, Dal-Gwon;Jeong, Yeong-Jin;Kim, Do-Won;Im, Chang-Hwan;Kim, Beop-Min
    • Proceedings of the Optical Society of Korea Conference
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    • 2009.10a
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    • pp.151-152
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    • 2009
  • 최근 신경과학 분야에서 대뇌피질 영역 간 연관성 분석은 신경학적 질병 (자폐증, 간질, 정신 분열증)의 분석 및 진단에 적용되고 있다. 기존 대뇌피질 영역 간 연관성 분석은 뇌전도 (EEG), 기능적 자기공명영상 (fMRI), 뇌자도 (MEG)등이 이용되었지만, 뇌전도의 낮은 공간분해능, 기능적 자기공명영상의 낮은 시분해능 등은 영역 간 연관성 분석에 단점으로 작용되고 있다. 반면, 근적외선 분광법(NIRS)은 대뇌피질에서의 혈류변화(oxy-, deoxy-hemoglobin)를 비침습적이며 빠른 시분해능으로 측정할 수 있는 방법으로 최근 신경과학 분야에 응용되고 있다 [1-2]. 본 논문에서는 근적외선 분광법을 이용한 대뇌피질영역 간 연관성 분석의 효용성을 입증하기 위해, 쥐의 수염자극 시 대응되는 지역 (일차-, 이차 체감각피질, 일차 운동피질 영역)에서의 혈류변화 신호의 영역 간 연관성 분석을 하였다. 본 연구결과에 의하면 수염자극 시 일차-, 이차 체감각피질 영역에서의 방향성은 확인할 수 없었고, 일차-, 이차 체감각피질 영역에서 일차 운동피질영역으로의 방향성은 확인할 수 있었다. 본 결과는 기존 수염자극 시 활성화되는 전기신호의 패턴과 일치하며, 향후 신경과학적 질병의 분석 및 진단에 근적외선을 이용한 대뇌피질 영역 간 연관성 분석이 유용할 수 있음을 보여준다.

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A novel encoder of digital and analog hybrid type for servo control with high-precision resolution (디지털 아날로그 혼합형 고정도 엔코더 개발)

  • 홍정표;박성준;권순재
    • The Transactions of the Korean Institute of Power Electronics
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    • v.8 no.6
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    • pp.512-518
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    • 2003
  • Position controls are very important in semiconductor manufacturing devices, machine tools Precision measuring instruments, etc. To measure the distance of movement of moving objects in minute units and the accuracy of measurement for the moving distance in these devices affect the performance of the whole devices. Therefore, in those Precision instruments, a sensing device that can measure the distance of movement with high-precision resolution is required. In this paper, a novel encoder of digital and analog hybrid type is proposed. It is shown that from this experiment a high-resolution angle measurement device can be designed by a low cost incremental encoder.

A Multilinear LDA Method of Tensor Representation for ECG Signal Based Individual Identification (심전도 신호기반 개인식별을 위한 텐서표현의 다선형 판별분석기법)

  • Lim, Won-Cheol;Kwak, Keun-Chang
    • Smart Media Journal
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    • v.7 no.4
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    • pp.90-98
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    • 2018
  • A Multilinear LDA Method of Tensor Representation for ECG Signal Based Individual Identification Electrocardiogram signals, included in the cardiac electrical activity, are often analyzed and used for various purposes such as heart rate measurement, heartbeat rhythm test, heart abnormality diagnosis, emotion recognition and biometrics. The objective of this paper is to perform individual identification operation based on Multilinear Linear Discriminant Analysis (MLDA) with the tensor feature. The MLDA can solve dimensional aspects of classification problems in high-dimensional tensor, and correlated subspaces can be used to distinguish between different classes. In order to evaluate the performance, we used MPhysionet's MIT-BIH database. The experimental results on this database showed that the individual identification by MLDA outperformed that by PCA and LDA.

Image enhancement in ultrasound passive cavitation imaging using centroid and flatness of received channel data (수신 채널 신호의 무게중심과 평탄도를 이용한 초음파 수동 공동 영상의 화질 개선)

  • Jeong, Mok Kun;Kwon, Sung Jae;Choi, Min Joo
    • The Journal of the Acoustical Society of Korea
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    • v.38 no.4
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    • pp.450-458
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    • 2019
  • Passive cavitation imaging method is used to observe the ultrasonic waves generated when a group of bubbles collapses. A problem with passive cavitation imaging is a low resolution and large side lobe levels. Since ultrasound signals generated by passive cavitation take the form of a pulse, the amplitude distribution of signals received across the receive channels varies depending on the direction of incidence. Both the centroid and flatness were calculated to determine weights at imaging points in order to discriminate between the main and side lobe signals from the signal amplitude distribution of the received channel data and to reduce the side lobe levels. The centroid quantifies how the channel data are distributed across the receive channel, and the flatness measures the variance of the channel data. We applied the centroid weight and the flatness to the passive cavitation image constructed using the delay-and-sum focusing and minimum variance beamforming methods to improve the image quality. Using computer simulation and experiment, we show that the application of weighting in delay-and-sum and minimum variance beamforming reduces side lobe levels.

Effect of Measuring Method on the Evaluation of Piezoelectric and Dielectric Properties of PMN-PT Single Crystal (PMN-PT 단결정의 압전 및 유전 특성 평가에 미치는 측정 방법의 영향)

  • Kim, Yong Soo;Park, Jae Hwan;Lee, Jeongho;Lee, Sang Goo
    • Journal of the Microelectronics and Packaging Society
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    • v.26 no.4
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    • pp.69-74
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    • 2019
  • The influence of measuring fixtures on the measurement of dielectric and piezoelectric properties of PMN-PT single crystal specimens was investigated. As the pressure of the jig pin which applied the AC electrical signal to the sample decreased, the lower resonance resistance was measured and the higher mechanical quality factor was calculated. The mechanical quality factor was 418 when the spring tension of the jig pin was 20grf, and the value of the quality factor was reduced by half when the spring tension was 200grf. The 4-probe fixture method is unsuitable for measuring piezoelectric properties, but it was suitable for the measurement of dielectric loss. In order to accurately evaluate the piezoelectric properties of PMN-PT, it is necessary to lower the spring tension of the jig pin as much as possible.

Physical Vapor Deposition공정 시, Substrate 온도에 따른 X-선 검출용 비정질 셀레늄의 성능평가

  • Kim, Dae-Guk;Gang, Jin-Ho;Kim, Jin-Seon;No, Seong-Jin;Jo, Gyu-Seok;Sin, Jeong-Uk;Nam, Sang-Hui
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.08a
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    • pp.210.2-210.2
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    • 2013
  • 현재 국내의 상용화된 디지털 방식 X-선 영상장치에서 간접변환방식은 대부분 CsI를 사용하고 있으며, X-선 흡수에 의해 전기적 신호를 발생시키는 직접변환방식은 Amorphous Selenium(a-Se)을 사용한다. a-Se은 진공 중에 녹는점이 낮아 증착시 substrate의 온도에 따라 민감한 변화를 보인다. 본 연구에서는 간접변환방식에 비해 높은 영상의 질을 획득할 수 있는 직접변환방식의 a-Se기반 X-선 검출기 제작 시 substrate에 인가된 온도에 따른 특성을 연구하여 최적화 된 substrate의 온도를 알고자 한다. 본 실험에서는 glass에 투명한 전극물질인 Indium Tin Oxide (ITO)가 electrode로 형성된 substrate를 사용하였으며 그 상단에 a-Se을 Physical Vapor Deposition (PVD)방식을 거쳐 X-선 검출기 샘플을 제작하였다. PVD 공정 시 네 개의 보트에 a-Se 시료를 각각 100g씩 총 400g을 넣고, $5{\times}10-5Torr$까지 진공도를 낮추었다. 보트의 온도는 $270^{\circ}C$에서 40분 $290^{\circ}C$에서 90분으로 온도를 인가하여 a-Se을 기화시켜 증착하였다. 증착 시 substrate 온도를 각각 $20^{\circ}C$, $40^{\circ}C$, $60^{\circ}C$, $70^{\circ}C$ 네 종류로 나누어 실험을 진행하였다. 끝으로 증착된 a-Se 상단에 Au를 PVD방식으로 electrode를 형성시켜 a-Se기반의 X-선 검출기 샘플 제작을 완료하였다. 제작된 a-Se기반의 X-선 검출기 샘플의 두께는 80에서 $85{\mu}m$로 온도에 따른 차이가 없었다. 이후에 전기적 특성을 평가하기위해 electrometer와 oscilloscope를 이용하여 Dark current와 Sensitivity를 측정하여 Signal to Noise Ratio(SNR)로 도출하였으며 Scanning Electron Microscope(SEM) 표면 uniformity를 관찰하였다. 또한 제작된 a-Se기반 X-선 검출기 샘플의 hole collection 성능을 확인하고자 mobility를 측정하였다. 측정결과 a-Se의 work function을 고려한 $10V/{\mu}m$기준에서 70kV, 100mA, 0.03sec의 조건의 X-선을 조사 하였을 때 Sensitivity는 세 종류의 검출기 샘플이 15nC/mR-cm2에서 18nC/mR-cm2으로 비슷한 양상을 나타내었지만, substrate온도가 $70^{\circ}C$때의 샘플은 10nC/mR-cm2이하로 저감됨을 알 수 있었다. 그리고 substrate온도 $60^{\circ}C$에서 제작된 검출기 샘플의 전기적 특성이 SNR로 환산 시, 15.812로 가장 우수한 전기적 특성을 나타내어 최적화 된 온도임을 알 수 있었다. SEM촬영 시 온도상승에 따라 표면 uniformity가 우수하였으며, Mobility lifetime에서는 $60^{\circ}C$에서 제작된 검출기 샘플이 deep trap 수치가 높아 hole이 $0.04584cm2/V{\cdot}sec$$0.00174cm2/V{\cdot}sec$의 electron보다 26.34배가량 빠른 것을 확인하였다. 본 연구를 통해 a-Se증착 시, substrate에 인가된 온도는 균일한 박막의 형성 및 표면구조에 영향을 미치며 온도가 증가할수록 안정적인 전기적 특성을 나타내지만 $70^{\circ}C$이상일 시, a-Se층의 결정화가 생겨 deep trap을 발생시켜 전기적 특성이 저하됨을 확인 할 수 있었다. 따라서 증착 시의 substrate의 온도 최적화는 a-Se기반 X-선 검출기의 안전성 및 성능향상을 위해 불가피한 요소가 된다고 사료된다.

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